Interface Bioactive Bone Cement Technique Research Articles

Radiological evaluation of cemented acetabular component in primary total hip arthroplasty with or without interface bioactive bone cement technique

PurposeWe evaluated the medium-term radiological outcomes of the interface bioactive bone cement (IBBC) technique used in the acetabular component in primary cemented total hip arthroplasty (THA). MethodsIn total, 79 patients (88 hips) who underwent primary THA at our hospital between January 2004 and April 2009 were divided into the non-IBBC (NIBBC; n ​= ​39 patients, 44 hips) and IBBC (n ​= ​40 patients, 44 hips) groups. A clear zone (CZ) at the cement-bone interface around the cup was evaluated 5 and 10 years postoperatively. The CZ score, which indicates the spread of the CZ, and loosening of the cup (CZ ​> ​2 ​mm on all sides or movement of the cup >4°) were also evaluated. ResultsNo patient had loosening of the cup. The mean patient age at surgery was 66.5 ​± ​9.2 years in the NIBBC group and 61.9 ​± ​7.7 years in the IBBC group (p ​= ​0.012). At 5 years postoperatively, the incidence of CZ was 36.4 ​% in the NIBBC group and 18.2 ​% in the IBBC group (p ​= ​0.056). At 10 years postoperatively, the incidence of CZ was 36.4 ​% in the NIBBC group and 20.1 ​% in the IBBC group (p ​= ​0.098). Age at surgery (p ​= ​0.045) significantly affected the incidence of CZ at 5 years but not at 10 years. The IBBC technique (p ​= ​0.042) and age at surgery (p ​= ​0.028) significantly affected the CZ score at 5 years. The IBBC technique (p ​= ​0.036) significantly affected the CZ score at 10 years. ConclusionsThe IBBC technique resulted in a significantly lower CZ score than the NIBBC technique in patients undergoing THA.

Risk factors for a radiolucent line around the acetabular component with an interface bioactive bone cement technique after primary cemented total hip arthroplasty

AimsThe main aims were to identify risk factors predictive of a radiolucent line (RLL) around the acetabular component with an interface bioactive bone cement (IBBC) technique in the first year after THA, and evaluate whether these risk factors influence the development of RLLs at five and ten years after THA.MethodsA retrospective review was undertaken of 980 primary cemented THAs in 876 patients using cemented acetabular components with the IBBC technique. The outcome variable was any RLLs that could be observed around the acetabular component at the first year after THA. Univariate analyses with univariate logistic regression and multivariate analyses with exact logistic regression were performed to identify risk factors for any RLLs based on radiological classification of hip osteoarthritis.ResultsRLLs were detected in 27.2% of patients one year postoperatively. In multivariate regression analysis controlling for confounders, atrophic osteoarthritis (odds ratio (OR) 2.17 (95% confidence interval (CI), 1.04 to 4.49); p = 0.038) and 26 mm (OR 3.23 (95% CI 1.85 to 5.66); p < 0.001) or 28 mm head diameter (OR 3.64 (95% CI 2.07 to 6.41); p < 0.001) had a significantly greater risk for any RLLs one year after surgery. Structural bone graft (OR 0.19 (95% CI 0.13 to 0.29) p < 0.001) and location of the hip centre within the true acetabular region (OR 0.15 (95% CI 0.09 to 0.24); p < 0.001) were significantly less prognostic. Improvement of the cement-bone interface including complete disappearance and poorly defined RLLs was identified in 15.1% of patients. Kaplan-Meier survival analysis for the acetabular component at ten years with revision of the acetabular component for aseptic loosening as the end point was 100.0% with a RLL and 99.1% without a RLL (95% CI 97.9 to 100). With revision of the acetabular component for any reason as the end point, the survival rate was 99.2% with a RLL (95% CI 97.6 to 100) and 96.5% without a RLL (95% CI 93.4 to 99.7).ConclusionThis study demonstrates that acetabular bone quality, head diameter, structural bone graft, and hip centre position may influence the presence of the any RLL.Cite this article: Bone Joint Open 2021;2(5):278–292.

Minimum 5year follow-up of clinical and radiographic results of cemented acetabular components with an interface bioactive bone cement technique in primary cemented total hip arthroplasty.

A well-fixed cement-bone interface is a crucial factor for acetabular and femoral components in cemented total hip arthroplasty (THA). The aim of the present study was to evaluate the middle-term clinical and radiological results of fixing the acetabular component with an interface bioactive bone cement (IBBC) technique in primary cemented THA. We undertook a retrospective review was undertaken of 193 primary cemented THAs in 174 patients using acetabular components cemented with an IBBC technique and followed for a minimum of 5years (mean 8.3years; range 5-17years). Baseline data, clinical and radiological outcomes were evaluated. Japanese Orthopedic Association hip score and modified Harris hip scores demonstrated significant clinical improvement in all patients (p < 0.001). Radiolucent lines were detected in 15 hips (7.8%) at the first year and 24 hips (12.4%) at the final post-operative follow-up. The Kaplan-Meier survivorship with radiographic loosening as the end point was 97.8% [95% confidence interval (CI) 95.2-100]. With revision of the acetabular component for aseptic loosening as the end point, component survival was 99.0% (95% CI 97.5-100). With revision of the acetabular component for any reason as the end point, component survival was 97.0% (95% CI 93.9-100). Clinical and radiological results of the acetabular component with the IBBC technique in primary cemented THA were excellent.

Total Hip Arthroplasty around the Inception of the Interface Bioactive Bone Cement Technique.

BackgroundTo augment cement-bone fixation, Dr. Hironobu Oonishi attempted additional physicochemical bonding through interposition of osteoconductive crystal hydroxyapatite (HA) granules at the cement-bone interface in 1982. He first used the interface bioactive bone cement (IBBC) technique in 12 selected patients (12 hips) in 1982 (first stage) and followed them for 2 years. In 1985, the technique was applied in 25 total hip arthroplasty (THA) patients (second stage) and the effects were investigated by comparing the side with the IBBC technique and the other side without the IBBC technique. He has employed this technique in all THA patients since 1987 (third stage).MethodsIn the IBBC technique, HA granules (2 to 3 g) were smeared on the bone surface just before the acetabular and femoral components were cemented. In the first stage, 12 hips were operated using the IBBC technique in 1982. In the second stage, THA was performed without the IBBC technique on one side and with the IBBC technique on the other side within 1 year in 25 patients. In the third stage, THA was performed with the IBBC technique in 285 hips in 1987.ResultsIn the first stage patients, implant loosening was not detected at 30 years after operation. In the second stage patients, revision was required in 7 hips without the IBBC technique due to cup loosening (5 hips) and stem loosening (2 hips), whereas no hip was revised after THA with the IBBC technique at 26 years after operation. In the third stage patients, the incidence of radiolucent lines and osteolysis was very few at 25 years after operation.ConclusionsThe long-term follow-up of THA performed around the inception of the IBBC technique has revealed low incidences of radiolucent lines, osteolysis, and revision surgery.

A Long Term Histological Analysis of Effect of Interposed Hydroxyapatite between Bone and Bone Cement in THA and TKA

The standard cementing technique for total hip and knee arthroplasty (THA, TKA) was modified by interposing osteoconductive porous polycrystalline hydroxyapatite (HA) granules at the cement-bone interface to augment cement-bone bonding. Twenty-one specimens from the acetabulum and two specimens from the femur containing well-fixed bone-cement interface were retrieved five months to twenty-two years after THA and TKA with an interface bioactive bone cement technique. Histological findings were evaluated in terms of the retrieved sites, the interval between index operation and revision, patient age at retrieval and bone pathology. Dense bone ingrowth was observed in all specimens retrieved from the superior wall of the acetabulum. Cancellous bone ingrowth was observed in specimens retrieved from the infero-medial wall of the acetabulum. Connective tissue interposition and osteolysis were observed at the sites where hydroxyapatite granules were absent. Findings of bone ingrowth for the HA interposed retrievals were similar regardless of the interval between index operation and revision, patient age at retrieval, and bone pathology. Longer survivability of the bone-cement bonding was attributed more to the interposed HA granules. In spite of various degrees of aging, postmenopausal osteoporosis, and pathological bone condition the histological findings were not affected by the bone pathology. There was long-term direct contact between the bone and hydroxyapatite granules. Thus, the interface bioactive bone cement technique can ensure longevity of bone-cement bonding even after the onset of osteoporosis and for pathological bone conditions.

29 to 24 Year-Clinical Results of Total Hip Arthroplasty Cemented with HA by Interface Bioactive Bone Cement (IBBC)

To improve the fixation of bone and bone cement in THA we used Interface Bioactive Bone Cement technique (IBBC) since 1982. For prostheses 28 mm-alumina head with polyethylene socket (Kyocera Co.) were used. In IBBC not-resorbable pure crystalline HA granules (0.3– 0.5 mm) were smeared on the bone surface in one to three layers just before packing bone cement. Group 1: IBBC was used in six joints in 1982. Group 2: In 25 patients, conventional bone cement technique (non-IBBC) in the one hip (in 1985 to 1986) and IBBC technique in the other hip (in 1986) were performed in the same patients. Group 3: In 65 patients (71 joints) IBBC were performed. Neither radiolucent line nor osteolysis appeared in all case in group 1. In group 2 in Non-IBBC the appearance rate of radiolucent line and osteolysis were rather high, however in IBBC they were extremely low. In Non-IBBC loosening were seen in 5 joints in the acetabulum and in 2 joints in the femur. However, in IBBC there was no loosening. In group 3 the radiolucent line and the osteolysis appeared extremely low. There was no loosening. In Non-IBBC the appearance rate of radiolucent line and the osteolysis was very high and the rate of loosening was 20%. However, in IBBC, radiolucent line and osteolysis will be prevented eternally.

Bipolar migrationに対するImpaction bone graftingを併用した人工股関節再置換術

Bipolar migrationに対するImpaction bone graftingを併用した人工股関節再置換術

THA with Hydroxyapatite Granules at Cement-Bone Interface

To augment cement-bone bonding, we interposed hydroxyapatite granules at the cement-bone interface (bioactive bone cement technique). Hydroxyapatite granules (2-3 g) were smeared on the bone surface of the acetabulum and femur just before cementing. We used porous hydroxyapatite granules 300 to 500 microm in diameter from 1986 to 1988 (first generation) and granules 100 to 300 microm in diameter from 1989 to 1991 (second generation). We followed 151 patients (222 hips) in the first generation and 170 patients (252 hips) in the second generation. The minimum followup was 15 years (mean, 17.3 years; range, 15-20 years). Radiolucent lines or spaces less than 1 mm were observed in four hips (1.8%) in the first generation and in 15 hips (6.2%) in the second generation. Osteolysis was observed in one hip (0.5%) in the first generation and six hips (1.6%) in the second generation. We observed loosening in two cups (0.8%) in the second generation. The long-term clinical results suggest the interface bioactive bone cement technique combined with our other techniques results in low incidences of radiolucent lines (spaces) and osteolysis, and may increase the longevity of cemented THA. The data suggest the larger hydroxyapatite granules performed better than smaller ones. Level III, therapeutic retrospective cohort series. See the Guidelines for Authors for a complete description of levels of evidence.

A short-term result of total hip arthroplasty for young patients less than 50 years old using interface bioactive bone cement technique

A short-term result of total hip arthroplasty for young patients less than 50 years old using interface bioactive bone cement technique

Monitoring of blood pressure during total hip arthroplasty using interface bioactive bone cement technique

Monitoring of blood pressure during total hip arthroplasty using interface bioactive bone cement technique

Radiological Evaluation of the Femoral Component Fixed with Interface Bioactive Bone Cement in Revision Total Hip Arthroplasty

Thirty cases whose femoral side was operated with interface bioactive bone cement technique in revision total hip arthroplasty for aseptic loosening and followed for more than 6 years were evaluated. The present study includes 2 men and 28 women with an average age at operation of 60 years. Mean postoperative follow-up period was 9 years. Rerevision of femoral component was not found. Possible loosening was observed in 1 case, using the criteria of Harris. Among 21 cases whose cementing grade was assessed as B or C in postoperative x-ray, radiolucent line at bone-cement interface has disappeared before last follow-up in 11 cases. The present study revealed that the good result was obtained using the interface bioactive bone cement technique for reconstruction of aseptic femoral loosening.

Histologic Findings at 14 and 18 Years After Cemented Total Hip Arthroplasty With Interface Bioactive Bone Cement Technique

To augment cement-bone bonding in total hip arthroplasty, we interposed hydroxyapatite (HA) granules at the interface. We report the histologic findings of 2 cases 14 and 18 years after cemented total hip arthroplasty with this technique. We found that a thick bony layer was observed where rich layers of HA granules existed. In areas without HA granules, the trabeculae did not form a thick bony layer. These bony layers around HA granules were observed at the interface of non–weight-bearing and weight-bearing areas in 2 acetabula after long-term follow-up.

Preliminary Result of THA Using Interface Bioactive Bone Cement Technique Combined with Third Generation Cementing Technique

29 cases of primary total hip arthroplasty (THA) using interface bioactive bone cement technique (IBBC) combined with third generation cementing technique were evaluated clinically and radiologically. The present study includes 2 men 2 cases and 24 women 27 cases with an average age at operation of 63 years old (ranging 42 to 81). Mean postoperative follow up period was 17.3 months (ranging 12 to 23 months). Pre- and postoperative (1 year) evaluation using Japan Orthopaedic Association (JOA) hip score were 36.0, and 85.0 points, respectively. Postoperative cementing grade using Barrack’s classification was A in every case. At one year, radiolucent line at bone-cement interface was not observed, except one case of rheumatoid arthritis patient at zone 3 (Delee and Charnley) in the acetabular side. Neither osteolysis nor loosening was observed in every case. No major complications, such as infection, dislocation, pulmonary embolization, were observed. The present study revealed excellent short-term result was obtained by IBBC technique combined with third generation cementing technique for primary THAs.

Alumina Versus Polyethylene in Total Knee Arthroplasty

The cementless alumina total knee prosthesis, which uses alumina in the portions coming in contact with the bone and a combination of alumina and ultra-high molecular-weight polyethylene (UHMWPE) in the sliding portions, is referred to as a total condylar. Alumina total knee arthroplasty was performed on 137 patients, including 103 rheumatoid arthritis (RA) and 34 osteoarthrosis (OA) patients, from January 1982 to February 1985. The follow-up period was seven years 11 months and four years ten months, respectively. At follow-up evaluation, 108 patients were available for clinical and roentgenographic examinations, amounting to a 79% follow-up rate. At follow-up examination, 67 joints (62%) were completely pain free and 28 joints (26%) caused slight pain on bearing weight. Walking ability was recovered moderately in RA and markedly in OA. In RA, 14 of 84 knees were cemented and one knee was treated with loosening. Of 72 cementless implantations, 55 sustained displacing distally and one sustained loosening in the tibia, whereas 31 sustained displacing proximally and six sustained loosening in the femur. In OA, 21 cementless knees had 17 displacings in the tibia, and ten displacings and two loosenings in the femur. Scanning electron microscopy (SEM) observation of the UHMWPE surface in tibial plates revealed smoothing and burnishing. Alumina is far superior to metal for the sliding part, although it is not always best for the portion in contact with the bone. To resolve these problems, for cementless fixation, anchoring portions of Ti alloy and alumina implants were covered with beads and coated with hydroxyapatite. For cement fixation, "the interface bioactive bone cement technique" interposing hydroxyapatite granules between bone and cement was performed.

The direct lateral approach to the hip.

A direct lateral approach to the hip is described which allows adequate access for orientation of the implant, for the insertion ofthe cement and for the correction ofdiscrepancy in leg length. An anatomical observation was made that the gluteus medius muscle is inserted into the greater trochanter by a tendon and that the axis of the shaft of the femur lies anterior to the main bulk of the muscle which was left