A reliable prediction of event soil loss at the plot scale can be obtained by Universal Soil Loss Equation (USLE)-type models. For the Sparacia site (South Italy), the USLE-MB model was recently developed, in which the effect of the erosive agent is modeled using the rainfall erosivity index of the USLE by a power b1 > 1 of the runoff coefficient QR. In this investigation, the model is parameterized separately using plot data collected for rill and interrill events that occurred in the Sparacia experimental area. The values b1 = 1.406 and b1 = 1.012 were obtained for the interrill and rill databases, respectively, which revealed a different effect of the runoff coefficient on soil loss due to the two erosive processes. Different relationships expressive of topographic factors were also deduced. The USLE-MB estimation performance significantly improved when operating the distinction between the two databases compared with the model parameterized on the complete database. The model was particularly reliable in estimating the highest event soil loss values, which were associated with the occurrence of rills. Finally, the proposed parameterization procedure lends itself to being tested in the framework of empirical soil loss modeling.