This paper investigates the adaptive fixed-time stabilization problem for a class of uncertain high-order nonlinear systems with unknown measurement sensitivities and unknown control magnitude. Compared to existing practical fixed-time control approaches, our control strategy is capable of driving all states of uncertain high-order systems to the origin within a fixed time, rather than just ensuring their boundedness. Additionally, this study relaxes the restrictions on the nonlinear functions of the system, while overcoming challenges such as unknown control magnitude and unknown measurement sensitivity without prior boundaries. To achieve the control objectives, our control strategy consists of two main steps. Firstly, we divide the initial value of the high-order system into two cases, and construct adaptive controllers separately for each case by adding a power integral technique and backstepping method. Subsequently, the reliance of the stability time of the closed-loop high-order system on the initial value is eliminated by designing an appropriate controller switching mechanism. Finally, we provide a simulation example to validate the effectiveness of our control strategy.