The Trans-border Economic Cooperation Zone is a future-oriented crossborder cooperation model in which China and neighboring countries provide and share some territories, and promote cooperation not only in economic cooperation but also in non-economic fields such as justice and security. China has already built 12 cooperative districts with neighboring countries, promoting Belt & Road initiatives. Although US-NK talks about denuclearization are currently in a difficult situation, economic cooperation issues at the border among two Koreas and China may become important if North Korea’s reform and opening are realized. We can refer to the cross-border economic cooperation zone model that China is promoting with neighboring countries to jointly establish a special unification economic zone or to design a test bed for regional integration between two Koreas. In addition, the Trans-border Economic Cooperation Zone may be established in the Dandong or Hunchun areas of NK-China border (or China-unified Korea border) in the process of North Korea’s reform and reunification. Therefore, it is necessary to trace and research the development process of China’s trans-border economic cooperation zones such as Horgos, which is already developing considerably, to draw implications for Korea.