Integrated Research Program Research Articles

Impacts of Climate Change on Vector-Borne Diseases of Animals and Humans with Special Emphasis on Afghanistan

Vectors are organisms that transmit pathogenic microorganisms among animals and humans. Infections transmitted by the bites of blood-sucking arthropods are called vector-borne diseases (VBDs). This review highlights the impacts of climate change on the distribution, seasonal variation, and socioeconomic effects of VBDs in affected countries, especially Afghanistan. There is good enough evidence indicating that recent climate change has affected the interaction of the vector-pathogen-host cycle in many parts of the world. The emergence and re-emergence of bluetongue virus (BTV), Rift Valley Fever (RVF), lumpy skin disease (LSD), West Nile Virus (WNV), and malaria in new areas previously considered free of the diseases, and shift of seasonal occurrence of many VBDs in endemic areas, are the clear examples of climate change impacts on VDBs. Although significant progress has been made regarding VBD surveillance systems, diagnostic capacity, vaccine development, and vector control programs in resource-rich countries, failure in adaptation programs and ineffective mitigation strategies against VBDs in developing countries, especially in low and middle-income countries (LMICs), including Afghanistan facilitate widespread distribution of VBDs in these regions. Furthermore, developing drug resistance among the pathogens and their vectors makes the conditions more suitable for VBDs wide dispersion. Such situations cause severe health and socio-economic burdens to affected countries. Developing early-warning systems for detecting VBDs, identifying and developing resistant livestock species and breeds, and applying interceptive measures based on integrated research programs are crucial to effectively reduce the harmful impacts of VBDs on human and animal populations.

Special Issue on ICoE Taipei Integrated Research on Disaster Risk

Established in 2010 as an integrated research program for disaster risk reduction, the IRDR ICoE Taipei is co-sponsored by the International Science Council (ISC) and the United Nations Office for Disaster Risk Reduction (UNDRR). In the past decade, the IRDR ICoE Taipei has received hundreds of participants around the world to the more than a dozen international training workshops (AI, Advanced Institute) it has organized. These workshops focused mostly on the capacity building program for disaster risk reduction. Bearing this in mind, one important motivation for this Special Issue was to encourage the participants of each Advanced Institute, in particular those who were awarded Seed Grants to conduct one-year projects following each workshop, to publish the results of their studies on the topics related to disaster risk reduction. In this Special Issue, the first paper provides a brief review of the capacity building program of the IRDR ICoE Taipei, followed by three research articles. Viola van Onselen and her co-workers in Taiwan present a methodology of strategies of ecosystem-based disaster risk reduction, with several case studies in coastal environments of Taiwan. Shyamli Singh of India proposes an integrated system for sustainable rice economics linking from farm to market, a case study on one of the largest rice production fields on the Indo-Gangetic plain. From the engineering perspective, Wen-Yi Huang and his colleagues in Taiwan and Australia present a paper dealing with the reinforcement of soil walls to prevent geohazards on the roads. This is the first special issue produced as a collaboration between the IRDR ICoE Taipei and the JDR, with great support from the National Science and Technology Center for Disaster Reduction (NCDR) and Academia Sinica of Taiwan. We hope there will be more Special Issues to come in the next few years.

Assessment of the applicability of a model for aviation-related ultrafine particle concentrations for use in epidemiological studies

Background and objectivesIn recent years it has been shown that aircraft emissions are a dominant source of ultrafine particles in the surroundings of airports. However, health effects of long-term (monthly to yearly) exposure to these particles are unknown. As part of an integrated research program into the health risks of ultrafine particles around Schiphol Airport, the applicability of the dispersion model STACKS+ to assess long-term exposure to ultrafine particles from aviation was assessed. MethodologyA detailed comparison between modelled and measured particle number concentrations (PNC) due to aircraft emissions was carried out at ten locations in the surroundings of Schiphol Airport during two six-month periods in 2017 and 2018. In order to deduce the contribution of aviation to measured PNC, we applied a fitting method of the sum of the modelled contributions from aviation, the modelled contributions from traffic on main roads and the contributions from outside the study area estimated from the measurements, to the measured total PNC. The analysis yielded scaling factors and uncertainty estimates for each of the main contributions. We then subtracted the estimated background and modelled contributions of road traffic from the total measured PNC and took the remainder as an approximation of the measured contribution from aviation to PNC. We compared it to the modelled contribution from aviation, based on the averaged values for the six-month periods. ResultsBoth six-month averaged modelled and measured PNC due to aircraft emissions (i.e., adjusted for background) showed a large range at the monitoring locations representative for population exposure (from close to zero to 10 000 particles/cm3). Spearman and Pearson correlation coefficients between model and measurement results were high (>0.83). ConclusionsThe applied approach enabled us to obtain a robust estimate of the contribution of aviation to the measured PNC. The dispersion model is able to determine the spatially varying average concentrations due to aircraft emissions in residential areas over periods of 6 months, allowing for application in epidemiological studies into long-term exposure.

Managing and Governing Integrated Research Programmes: Lessons from Theory and Practice

Researchers are increasingly working in large, integrated science programmes. This is supposed to lead to several benefits, including creating and enhancing synergies amongst projects, improving collaboration and knowledge exchanges amongst researchers from different disciplines, and generating a higher return on investments in R&D. In practice, though, these benefits are often not fully realised, and large-scale integrated programmes can become frustrating for researchers. Additionally, they can result in insufficient integration and collaboration, and incur high overhead costs. In the present paper, the authors share their experience and insights on how to structure, manage and govern integrated programmes more competently. They do so by reflecting on their own practical experience in designing an integrated programme, and by drawing valuable insights from the literature on governance, management studies and organisational economics. The authors suggest that many problems can be linked to the implementation of programme management systems and coordination mechanisms that are poorly aligned with the unique characteristics of integrated programmes. They provide guidelines for programme managers to use systems that are a better fit, which can help researchers collaborate in a more engaging and productive manner while reducing the overhead costs associated with programme administration.

Impacts of Early Holocene environmental dynamics on open‐air occupation patterns in the Western Mediterranean: insights from El Arenal de la Virgen (Alicante, Spain)

ABSTRACTOpen‐air sites represent a fundamental proxy of the Early Holocene adaptive systems in the Iberian Peninsula. However, its research potential for the study of human–environmental interactions has been minimally explored. In this work, we present the results of an integrated research programme focused on open‐area excavations at the Mesolithic site of Arenal de la Virgen (Alicante, Spain). Novel multi‐scalar geoarchaeological and archaeo‐stratigraphic studies, coupled with featured‐based palaeobotanical analysis, were used to design an extensive radiocarbon dating programme and produce different Bayesian chronological models. Our results distinguish two different Mesolithic occupation phases, dating to 9.3–9.1 and 8.6–8.3k cal a bp respectively, consisting of combustion features and lithic scatters. The comparison of occupational dynamics with the nearby palaeoecological records of Salines and Villena indicated that both Mesolithic phases occurred under relatively stable environmental conditions. The second Mesolithic phase, however, ended during the onset of the 8.2k cal a bp climatic event, when sedimentation processes shifted from soil formation to accretion of aeolian sands. We demonstrate that the end of the Mesolithic occupations at Arenal de la Virgen coincides with the cessation of radiocarbon‐dated activity in other open‐air Postglacial sites in the central Mediterranean region of Iberia.

Long-term evolution of a carbonate reservoir submitted to fresh, saline and thermal waters interactions – Jurassic carbonates in the coastal area of the Gulf of Lion margin (southern France)

Securing and managing underground water resources requires a good knowledge of the structure, texture and connections of the reservoir, in order to develop realistic and reliable hydrogeological models. On the coastline of the Gulf of Lion Margin (S. France), the Balaruc-les-Bains deep karst reservoir is subjected to interactions between fresh, marine and deep thermal waters, respectively. Water resource usage for drinking, spa resort, and fish-farming raises important economic and social issues. These were addressed by an integrated research program, involving drilling of an exploratory borehole across the Jurassic carbonate reservoir. This contribution analyses the 750 m cores, in order to (i) characterise the architecture and evolution of the karst reservoir and (ii) investigate the paleo-fluids circulations, witnessed by calcite and dolomite mineralization in the fractures, karst cavities, and as cement of tectonic beccia. The structure of the reservoir is characterised by the superposition of several aquifers separated by marly intervals. At shallow level, the initial grainstone is incompletely dolomitized in metre-thick intervals, while limestone in the 210–340 m interval was completely dolomitized at an early stage. Dolomite has been subjected to penetrative extensional cataclastic deformation, while the preserved limestone is affected by normal faulting, resulting from NNE–SSW extension. Distinct types of karsts have been documented, from the top of the reservoir (paleo-lapiaz filled with Burdigalian marine marls), down to 500 m depth (paleo-endokarst filled with continental silts). The upper reservoir (75–150 m) is intensely karstified, and includes 0.1 to 1 m-wide cavities, where present day water fluxes are documented. Analyses of calcite and dolomite crystallisation under natural light and cathodoluminescence indicate precipitation from distinct fluids: formation water in chemical equilibrium with the host rock, water rich in oxides and hydroxides, ascending hydrothermal fluid and corrosive water of meteoric origin. Alternate dolomitization and calcitization observed in the upper reservoir suggests alternate flows of karstic freshwater and marine salt-water. Vertical, metre-long and centimetre wide open cracks are presently used for large water flows; several generations of syntaxial calcite growth provide evidence for varying chemistry of the circulating fluids. Structural cross cutting relationships allowed us to establish a relative chronology of events, which can be correlated with the regional geodynamic evolution. The study reveals that the present-day reservoir architecture results from the superimposition of structures formed during the Early Cretaceous extension, Maastrichtian-Eocene Pyrenean shortening, and Oligocene rifting of the Gulf of Lion. The reservoir was also shaped by successive karstification episodes and marine transgressions. Although the present-day hydrological system is controlled by, and reactivates structures inherited from a long-term evolution, it is characterised by frequent turn-overs of the water flow, tuned by high-frequency external forcings such as sea-level changes driven by Pleistocene glacio-eustasy, or varying precipitation rates.

Comments on effective use of numerical modelling and extended classical shell buckling theory

This paper argues that in the understandable enthusiasm to use the now readily available high-fidelity numerical software allowing the analysis of the complexities of shell buckling, and especially the notorious case of the axially loaded cylinder, there has been insufficient consideration of classical shell buckling theory and its more recent reduced stiffness extension. If future design is to be able to effectively exploit the potential benefits of the use of advanced composite materials and/or the use of rib reinforcement, it is suggested that these numerically driven research programmes would benefit from more explicit integration within the framework of classically extended buckling theory. This suggestion is reinforced in what follows by highlighting the results from a longstanding research programme in which classically extended buckling theory has been demonstrably enhanced through its integration with reliable numerical experimentation. This enhancement has helped to resolve a number of important issues including: identification of the most critical forms of imperfection affecting the buckling loads; how the most critical knockdown factors are influenced by changes in the shells' geometric and material characteristics and how safe design might be more explicitly related to the prescribed levels of geometric tolerances. Recommendations are made as to how such integrated research programmes could in the future further enhance our ability to design materially efficient shells against buckling.

Multidisciplinary care in chronic airway diseases: the Newcastle model.

Chronic airway diseases including asthma and COPD are prevalent and high-burden conditions with the majority of patients successfully managed in the primary care setting. However, for some patients with more complex disease such as difficult-to-treat or severe asthma, or complex COPD, tertiary care is required. This review provides an overview of the successful tertiary care multidisciplinary respiratory service that operates in Newcastle, New South Wales, Australia, which has been integrated into the tertiary care outpatient clinics for almost three decades. The service is multifaceted in terms of the clinical care it provides; it includes an “Inpatient Service”, “Asthma Management Service”, “Difficult Airways Clinic”, “Drug Administration Clinic”, “Rapid Access Clinic” and “Pulmonary Rehabilitation”, and has an integrated research programme. The core of the multidisciplinary approach to airway diseases is a person-centred model of care, the “Treatable Traits” approach. The staffing of this service comprises consultant physicians, respiratory advanced trainees, respiratory scientists, physiotherapists, speech pathologists, nurse specialists and a nurse consultant. Patients that present to this service undergo an initial assessment and clinical review by team members, synthesis of relevant data, and development of a diagnosis and management plan. Based on this clinical review, specific interventions are determined according to the traits identified. Over time the service has evolved to accommodate the increasing numbers of patients requiring access to the Difficult Airways Clinic assessment and therapies. This has been facilitated by partnering with the Centres of Excellence in Severe Asthma and Treatable Traits to develop educational and practice management tools.

Phosphorylation analysis of the Hippo-YAP pathway using Phos-tag

Phosphorylation is an essential regulatory mechanism in cells that modifies diverse substrates, such as proteins, carbohydrates, lipids, and nucleotides. Protein phosphorylation regulates function, subcellular localization, and protein-protein interactions. Protein kinases and phosphatases catalyze this reversible mechanism, subsequently influencing signal transduction. The dysregulation of protein phosphorylation leads to many diseases, such as cancer, neurodegenerative diseases, and metabolic diseases. Therefore, analyzing the phosphorylation status and identifying protein phosphorylation sites are critical for elucidating the biological functions of specific phosphorylation events. Unraveling the critical phosphorylation events associated with diseases and specific signaling pathways is promising for drug discovery. To date, highly accurate and sensitive approaches have been developed to detect the phosphorylation status of proteins.In this review, we discuss the application of Phos-tag to elucidate the biological functions of Hippo pathway components, with emphasis on the identification and quantitation of protein phosphorylation under physiological and pathological conditions. SignificanceWe here provide a comprehensive overview of Phos-tag technique-based strategies to identify phosphorylated proteins at the cellular level in the Hippo-YAP pathway that comprises a major driving force for cellular homeostasis. We clarify the links of applying Phos-tag in elucidating the biological functions of the Hippo pathway components with particular attention to the identification and quantitation of protein phosphorylation under physiological and pathological conditions.We believe that our paper will make a significant contribution to the literature because these detailed phosphorylation modifications and functional diversity of the Hippo pathway components in physiological and pathological processes are only beginning to come to the fore, highlighting the potential for discovering new therapeutic targets.Moreover, this line of research can provide further insight into the inextricable link between phos-tag applications as a molecular tool and cellular signaling modality, offering new directions for an integrated research program toward understanding cellular regulation at the molecular level. Given the broad research and practical applications, we believe that this paper will be of interest to the readership of your journal.

Optimising function and well-being in older adults: protocol for an integrated research programme in Aotearoa/New Zealand

BackgroundMaintaining independence is of key importance to older people. Ways to enable health strategies, strengthen and support whanāu (family) at the community level are needed. The Ageing Well through Eating, Sleeping, Socialising and Mobility (AWESSOM) programme in Aotearoa/New Zealand (NZ) delivers five integrated studies across different ethnicities and ages to optimise well-being and to reverse the trajectory of functional decline and dependence associated with ageing.MethodsWell-being, independence and the trajectory of dependence are constructs viewed differently according to ethnicity, age, and socio-cultural circumstance. For each AWESSoM study these constructs are defined and guide study development through collaboration with a wide range of stakeholders, and with reference to current evidence. The Compression of Functional Decline model (CFD) underpins aspects of the programme. Interventions vary to optimise engagement and include a co-developed whānau (family) centred initiative (Ngā Pou o Rongo), the use of a novel LifeCurve™App to support behavioural change, development of health and social initiatives to support Pacific elders, and the use of a comprehensive oral health and cognitive stimulation programme for cohorts in aged residential care. Running parallel to these interventions is analysis of large data sets from primary care providers and national health databases to understand complex multi-morbidities and identify those at risk of adverse outcomes. Themes or target areas of sleep, physical activity, oral health, and social connectedness complement social capital and community integration in a balanced programme involving older people across the ability spectrum.DiscussionAWESSoM delivers a programme of bespoke yet integrated studies. Outcomes and process analysis from this research will inform about novel approaches to implement relevant, socio-cultural interventions to optimise well-being and health, and to reverse the trajectory of decline experienced with age.Trial registrationThe At-risk cohort study was registered by the Australian New Zealand Clinical Trials registry on 08/12/2021 (Registration number ACTRN 12621001679875).

The Role of Federal Research Centers in Implementing the Strategic Priorities of Scientific and Technological Development of Russia

The image of Russian science will change with the adoption of the new state program: Scientific and technological development of the Russian Federation. This paper discusses the reasons for such a significant transformation of science, and defines the tasks of federal research centers in the new system. Three federal centers of the European North of Russia were chosen as the objects of the study including Karelian, Kola and Komi Federal Research Centers. The paper briefly describes the history of the creation of a regional network of scientific organizations and their tasks. It also gives some examples of successful complex interdisciplinary cooperation between these three scientific organizations during the Soviet period. The attention is focused on the challenges facing the scientific organizations at present and the tools proposed for solving these. The tools primarily include a project approach and mechanisms for organizing complex interdisciplinary research, such as federal scientific and technical programs, integrated research programs, scientific educational centers at the international level, and the strategic academic leadership program Priority-2030. These aim to concentrate the efforts of researchers on the priority tasks of developing science and the most important sectors of the country’s economy. Federal research centers have a number of advantages over ordinary scientific organizations when science begins to concentrate in large ‘regions of knowledge’. Due to redistribution of internal reserves, they can initiate new research trends, points of growth, and joint research within the framework of integration projects.
 Keywords: federal research centers, project management, grand challenges, networking tools

Developing a Personalized Integrative Obesity-Coaching Program: A Systems Health Perspective.

Current obesity management strategies are failing to achieve sustainable and favorable long-term results. We propose a more personalized, dynamic, and systemic perspective on the interactions of key determinants and coaching advice on obesity. The aim of this study was to use a systems view on overweight, complexity science, and a transdisciplinary process to develop a five-year personalized integrative obesity-coaching and research program. Managers, medical specialists, clinical psychologists, dieticians, physical- and psychomotor therapists, and lifestyle coaches aligned their perspectives and objectives with experts in systems thinking and systems biology. A systems health model of obesity was used to identify the causal relations of variables with the most influence on obesity. The model helped to align and design a personalized integrative obesity-coaching program and to identify the key variables to monitor the progress and to adjust the personalized program, depending on the goals and needs of the participant. It was decided to use subtyping of participants by a systems biologist, based on traditional Chinese medicine symptoms, as a novel method to personalize the intervention. The collaborative transdisciplinary approach based upon a systems view on obesity was successful in developing a personalized and adaptive five-year obesity-coaching and research program.

Estudos de biodiversidade marinha e costeira, 60 anos de financiamento à pesquisa da FAPESP, o que aprendemos e desafios futuros

Abstract In this study we survey and analyze 300 projects related to marine biodiversity funded by FAPESP from 1972 to 2021, of which 46 were nested in the BIOTA Program. From a unique project in the 1970’s, the number gradually increased until 2009, when BIOTA promoted a call on marine biodiversity, which led to a boost in the number of funded projects in the subsequent years. The geographical range of the projects expanded over the years and, from studies based on the coast of São Paulo State, the focus gradually shifted to broader areas of the Brazilian coast, then to other areas of the Atlantic, and eventually became global. The majority of projects focused on coastal benthic organisms living on hard-bottom. In terms of taxa, six groups accounted for about 60% of the projects (viz. Crustacea, Actinopterygii, Mollusca, Chondrichthyes, Cnidaria, and Rhodophyta), but it is observed an increase in the number of groups studied over the decades. The 300 projects refer to a set of 82 different topics, of which the top five are taxonomy, phylogeny, community, “omics”, and pollution. The analyses show a long-standing effort in marine biodiversity surveys, with ongoing updated approaches regarding scope and methods. Research on strategic areas is discussed, including deep-sea and marine microbiota. Climate change and the increasing pressure of human activity on the ocean, including pollution, acidification and invasive species, are among the main challenges for the future. Projects producing and using basic research data in an integrative and transdisciplinary way offer multiple perspectives in understanding changes in ecosystem functioning and, consequently, are essential to support public policies for the conservation and sustainable use of marine biodiversity at different scales. UNESCO’s Decade of Ocean (starting 2021) is a window of opportunity to strengthen marine research, to promote national and international collaboration, to build up networks involving the public and private sector, but particularly to draw society’s attention to the importance of knowing marine environments and using ocean resources in a sustainable way. The advancement of ocean literacy is one of the main legacies for future generations promoted by integrated research programs such as BIOTA-FAPESP.

Region as a Territory in the Management Practices of Interaction With Sociocultural Senters

The key research interest of this paper is focused on identifying the presence and nature of opportunities for interaction between the region as an integral entity and its urban territories, represented by specific socio-cultural centers in the field of management practices. The author identifies the conceptual components of interactions of the region as a whole and its urban settlements, at the institutional level and in the views of the leaders: “moral region”, “neighborhood effect”, “cultural potential of the city”, which allow to identify contradictions in the studied object and outline further research prospects. Transformation of basic social institutions – family, education, culture, religion at the level of the region makes this property is transitive, which requires the use of nonlinear analysis approach to study its Genesis, identify the key approaches to understanding that in the future will allow us to build an integrated research program. The methodological model of the study is based on the integral approach of the founder of American urban sociology R. Park and the Russian urban scientist V.L. Glazychev. This allows us to generalize the existing data on the issue of interest to us and to find common patterns in the development of urban socio-cultural centers, as well as to analyze management practices. The empirical basis of the research is based on (1) semi-structured interviews with the heads of socio-cultural centers of urban settlements (libraries, museums, galleries, theaters, etc.) (n=10) conducted by the author in 2020; (2) data from the territorial body of the Federal state statistics service for the Kursk region for 2019; (3) secondary data from studies conducted in the socio-cultural centers of the Tobolsk, Ulyanovsk regions, the North Caucasus and Yakutia. As auxiliary methods, the study uses such General scientific methods as comparative analysis and comparative analysis of secondary sociological data. A descriptive method was also used to determine the degree of knowledge of management practices in the development of urban socio-cultural centers. For a comprehensive assessment of regional urban communities as an object of management influence, the analysis of statistical data for recent years was used.The author’s conclusions can be formulated as follows: first, the interaction of urban territorial entities with the region as an integral system is currently presented as an institutionalized reserve for the development of its socio-cultural potential, establishing intra-and interregional relations; second, the main contradictions found in the results of the study were recorded in the twentieth century, and still remain unresolved: at the regional level and at the level of individual territories, managers measure the effectiveness of their work by heating up resources, increasing volumes and formalizing activities, while the population prefers a qualitative transformation of reality with elements of innovation and filling existing voids in the architectural and symbolic sense.

Evolution, Homology, and Development of Tetrapod Limb Muscles

Since the early 1900s, researchers have attempted to unravel the origin and evolution of tetrapod limb muscles using a combination of comparative anatomy, phylogeny, and development. The methods for reconstructing soft tissues in extinct animals have been refined over time as our ability to determine muscle homology and phylogenetic relationships between tetrapods has improved. Since many muscles do not leave osteological correlates, muscle reconstruction in extinct animals is largely based on anatomy and development in extant animals. While muscle anatomy in extant tetrapods is quite conservative, the homologies of certain muscles between taxonomic groups are still uncertain. Comparative developmental studies can help to resolve these controversies, as well as revealing general patterns of muscle morphogenesis across tetrapod groups. We review the methods, results, and controversies in the muscle reconstructions of early members of the amniote, mammalian, and lissamphibian lineages, including recent attempts to reconstruct limb muscles in members of the tetrapod stem group. We also review the contribution of recent comparative developmental studies toward understanding the evolution of tetrapod limb muscles, including morphogenic gradients, the origin of paired fins, and the evolution of morphological complexity. Finally, we discuss the role of broad, comparative myological studies as part of an integrative research program on vertebrate evolutionary biology.

Elevation, oxygen, and the origins of viviparity.

Research focused on understanding the evolutionary factors that shape parity mode evolution among vertebrates have long focused on squamate reptiles (snakes and lizards), which contain all but one of the evolutionary transitions from oviparity to viviparity among extant amniotes. While most hypotheses have focused on the role of cool temperatures in favoring viviparity in thermoregulating snakes and lizards, there is a growing appreciation in the biogeographic literature for the importance of lower oxygen concentrations at high elevations for the evolution of parity mode. However, the physiological mechanisms underlying how hypoxia might reduce fitness, and how viviparity can alleviate this fitness decrement, has not been systematically evaluated. We qualitatively evaluated previous research on reproductive and developmental physiology, and found that (1) hypoxia can negatively affect fitness of squamate embryos, (2) oxygen availability in the circulatory system of adult lizards can be similar or greater than an egg, and (3) gravid females can possess adaptive phenotypic plasticity in response to hypoxia. These findings suggest that the impact of hypoxia on the development and physiology of oviparous and viviparous squamates would be a fruitful area of research for understanding the evolution of viviparity. To that end, we propose an integrative research program for studying hypoxia and the evolution of viviparity in squamates.

Research effort devoted to regulating and supporting ecosystem services by environmental scientists and economists.

The economic valuation of ecosystem services in part reflects the desire to use conventional economic tools (markets and economic instruments) to conserve ecosystem services. However, for regulating and supporting ecosystem services that depend on ecosystem structure and function, estimation of economic value requires estimates of the current level of underlying ecological functions first. This primary step is in principle, the job of environmental scientists, not economists. Here, we provide a coarse-level quantitative assessment of the relationship between the research effort expended by environmental scientists (on the biophysical values) and economists (on the monetary values) on 15 different regulating and supporting services in 32 ecosystem types using peer-reviewed article hits retrieved from bibliographic databases as a measure of research effort. We find a positive, moderately strong (r = 0.69) correlation between research efforts in the two domains, a result that, while encouraging, is likely to reflect serendipity rather than the deliberate design of integrated environmental science-economics research programs. Our results suggest that compared to environmental science research effort economic valuation is devoted to a smaller, less diverse set of ecosystem services but a broader, more diverse, set of ecosystem types. The two domains differed more with respect to the ecosystem services that are the major focus of research effort than they did with respect to the ecosystem types of principal research interest. For example, carbon sequestration, erosion regulation, and nutrient cycling receive more relative research effort in the environmental sciences; air quality regulation in economic valuations. For both domains, cultivated areas, wetlands, and urban/semi-urban ecosystem types received relatively large research effort, while arctic and mountain tundra, cave and subterranean, cryosphere, intertidal/littoral zone, and kelp forest ecosystem types received negligible research effort. We suggest ways and means by which the field of sustainability science may be improved by the design and implementation of a searchable database of environmental science and economic valuation literature as well as a global ecosystem service research network and repository that explicitly links research on the estimation and prediction of biophysical ecosystem functions with that of the social sciences and other knowledge systems. These suggestions would, at least in principle, facilitate a more efficient research agenda between economists and environmental scientists and aid management, regulatory and judicial decision-makers.

Global Governance in Complex Times: Exploring New Concepts and Theories on Institutional Complexity

This article, and the special issue it introduces, seek to contribute to the emerging and much-needed dialogue between the study of global governance and the study of social complexity. We hold that, while there is wide acceptance that global governance is becoming increasingly complex, studying this complexity still faces significant challenges in terms of concepts, theory, and methodology.The article outlines why that dialogue is needed, and how the complexity sciences can help us address some of these challenges. It then introduces key questions central to such an integrated research programme, for instance: under what conditions can a global governance system be regarded as complex? Which methods can help us recognize and assess patterns of stability, iteration, and change in global governance? How can a theory-driven analysis take into account that complexity may influence spaces for political agency, i.e. that it may alter key aspects of legitimacy, accountability, transparency, technocracy, and power and ultimately the strategical options of certain actors? Finally, the article looks ahead to the special issue and summarizes how the authors contribute crucial conceptual, theoretical, and methodical ideas for addressing these and other questions.

Socio‐ecological lessons from the multiple landfalls of Hurricane Georges

AbstractOver the course of 16 d in the fall of 1998, Hurricane Georges made landfall on five Caribbean Island nations, two U.S. states, and two territories. Along its path, it impacted nearly every type of built environment and terrestrial and marine ecosystem found in the Caribbean and the southeastern United States. We reviewed ecological and sociological research related to Georges in order to demonstrate the potential power of regional synoptic networks despite notable gaps that existed at the time. Most studies examined various effects and responses within four years of the storm, though a few reported longer‐term results. Reduction in forest stem density was the most reported ecological effect and ranged from 7% to 51% among sites in different forest types. Forests previously impacted by Hurricane Hugo in 1989 showed lower mortality from Georges than forests with longer hurricane‐free intervals. Rivers in the storm's path exported heavy loads of sediment to marine systems. For example, 5–10 million tons of sediment was transported to marine systems from Puerto Rico, and suspended sediments increased tenfold in coastal Louisiana. Economic costs directly related to Hurricane Georges ranged from 5% to 200% of annual GDP in the year after the storm. Sociological research indicated that children and college students exposed to Hurricane Georges experienced elevated effects on mental health such as anxiety and depression for up to 2.5 yr. Established research areas and longitudinal studies were valuable in understanding hurricane effects in the context of long‐term trends but fragmented research capacity reduced both local and regional synthetic efforts. Georges provides a template of how future integrated research programs could provide a deeper understanding of how nature, urbanization, human culture, and societal norms interact, respond, and recover from a major hurricane. However, future studies should avoid using the Saffir‐Simpson scale as a shorthand indicator or predictor of storm effects because topographic, historical, ecological, political, infrastructural, and societal factors interact to alter storm effects. The breadth of topics addressed in the research produced after Georges shows the potential for transformative, regionally synthetic research that spans whole watersheds and nearshore areas while integrating ecological and social sciences.

The conservation of arboreal marsupials in the Albury‐Wodonga region of south‐eastern Australia

SummaryUrban expansion is a major cause of land use change and presents a significant threat to biodiversity worldwide. Agricultural land is often acquired by local councils and developers to expand urban growth boundaries and establish new housing estates. However, many agricultural landscapes support high biodiversity values, especially farmlands that feature mosaics of native vegetation and keystone habitat such as hollow‐bearing trees. In south‐eastern Australia, many arboreal marsupials including the threatened Squirrel Glider (Petaurus norfolcensis) have populations within peri‐urban zones of expanding rural cities. A key challenge to planners, developers and conservation organisations is the need to maintain habitat for locally rare and threatened species as land undergoes changes in management. Critical to the sustainable development of peri‐urban landscapes is a thorough understanding of the distribution, habitat requirements and resources available to maintain and improve habitat for species dependent on limited resources such as tree cavities. In this management report, we present background information on an integrated research programme designed to evaluate potential impacts of urban development on fauna in the Albury Local Government Area, NSW. We mapped hollow‐bearing trees, erected nest boxes and monitored arboreal marsupials. Information presented in this report provides a blueprint for monitoring arboreal marsupials, including threatened species in other developing regions, and will assist the Albury‐Wodonga local governments in future planning of sustainable living environments.