In this paper, we report a methodology, developed in the context of Smart Energy Efficient Middleware for Public Spaces European Project, aimed at exploiting ICT monitoring and control services to reduce energy usage and CO2 footprint in existing buildings. The approach does not require significant construction work as it is based on commercial-off-the-shelf devices and, where present, it exploits and integrates existing building management systems with new sensors and actuator networks. To make this possible, the proposed approach leverages upon the following main contributions: (a) to develop an integrated building automation and control system, (b) to implement a middleware for the energy-efficient buildings domain, (c) to provide a multi-dimensional building information modelling-based visualisation, and (d) to raise people’s awareness about energy efficiency. The research approach adopted in the project started with the selection, as case studies, of representative test and reference rooms in modern and historical buildings chosen for having different requirements and constraints in term of sensing and control technologies. Then, according to the features of the selected rooms, the strategies to reduce the energy consumptions were defined, taking into account the potential savings related to lighting, heating, ventilation, and air conditioning (HVAC) systems and other device loads (PC, printers, etc.). The strategies include both the control of building services and devices and the monitoring of environmental conditions and energy consumption. In the paper, the energy savings estimated through simulation, for both HVAC and lighting, are presented to highlight the potential of the designed system. After the implementation of the system in the demonstrator, results will be compared with the monitored data.