The Euro-American Consortium for Promoting the Application of Mathematics in Technical and Natural Sciences organized its 15th annual conference of the series AMiTaNS (Application of Mathematics in Technical and Natural Sciences). The event took place during June 21-26, 2023 in the Congress Centre of Black-Sea resort of Albena, Bulgaria. Its aim was to foster existing and new personal contacts, scientific discussion as well as to provide a forum for the exchange of ideas and experience between specialists in the fields of Mathematics, Physics, Biology, Ecology, Economics, Computer Science and Technology. The event became a world conference covering 15 time zones between Chile and Nebraska through Texas, Indiana, Alabama, Florida, the UK, Europe, Cyprus, Russia, and China. The conference was managed from the Congress Centre in Albena where 40 participants and delegates were present in person and the other 40 attended the event via Zoom video platform.Interest in this conference is growing year by year. This year we registered 70 talks and scientific reports, more than 80 participants – contributors and delegates from 16 countries around the world, representing the continents of Europe, North and South America, and Asia. About 18% of them attended the conference for the first time, with 50% of them being young scientists. The accepted talks were delivered and attended both on-location at the big hall and Corolla hall in Flamingo Grand hotel and on-line. Every day the morning sessions started by plenary lectures followed by contributed sessions on the following topics: Applied Analysis, Biomathematics, Continuum Mechanics, Mathematical Physics, Numerical Methods, Scientific Computing. As part of the program, leaders of their respective fields organized three special sessions: Statistics & Modeling, Mathematical Methods in Reliability Theory, Algebraic and Geometric Aspects of Integrable Systems. A number of very interesting presentations were delivered, which sparked stimulating scientific discussions both on- and off-line. The reader can find comprehensive and detailed information about the talks and reports including their records on the conference website at http://2023.eac4amitans.eu.All contributed manuscripts were reviewed by anonymous independent referees via Morressier platform, and the approved revised manuscripts were accepted for publication in the present volume. The continued success of AMiTaNS in defiance of the extraordinary circumstances and challenges faced in the last few years undoubtedly enhances its reputation as an established annual meeting with an eminent and continuously growing core of contributors. Yet, the hybrid format turned out very flexible both for the organizers and contributors. It makes the conference accessible to all those who wish to attend either in person or remotely. We would like to thank the plenary speakers, who accepted our invitation and contributed to the conference through their elucidating lectures. We would also like to thank the special sessions organizers, hosts and co-hosts for the high scientific quality of the talks they selected, and for ensuring the smooth running of the conference in hybrid format. We are deeply indebted to the scores of anonymous referees all over the world, who approached their duties very professionally and thoroughly, and helped us to maintain high scientific standards. We highly appreciate the involvement of the members of the Program Committee and Steering Committee, who supported AMiTaNS from its inception, and worked tirelessly throughout the intensive labors of advertising, arranging, organizing, and reviewing. Special thanks go to our colleagues from the University of Essex at Colchester, UK, who worked with dedication so that parallel Zoom conference sessions could be held completely on-line.We are very grateful to our publisher Institute of Physics, Bristol, UK for the helpful cooperation during the preparation of this volume.List of Program Committee, Organizer, Sponsor, Participants are available in this Pdf.