Organizations are relying more on database servers as storage for important information. This makes it imperative for strong measures against cyber-attack to safeguard sensitive data. The study focusses on some advanced ways of protecting database servers from cyber-crime and these are: SQL injection prevention, role-based access control, data encryption techniques, and insider threat mitigation. It also looks into the latest developments in the area such as machine learning based abnormality detection, Zero Trust architecture, and multi-factor authentication. Such practices make it possible to establish a multi-layered defensive mechanism that enhances data protection by considering the outside as well as inside dangers. Besides compliance with regulations, maintaining visibility and patch management is vital so as to remain ahead of changing cyberspace dangers. Therefore, this research presents an array of recommendations to address the entire security landscape for resilient database platforms against sophisticated assaults. The conclusions point out that there is need to amalgamate these practices towards ensuring safety in terms of risks related with contemporary database server setups. Key Words: Database Security, SQL Injection, Role-Based Access Control, Data Encryption, Insider Threat, Zero Trust Architecture.
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