Insecticides In Tissues Research Articles

Selenium, cadmium and diazinon insecticide in tissues of rats after peroral exposure

The concentrations of selenium (Se), cadmium (Cd) and diazinon (DZN) in selected tissues of rats after an oral administration in various combinations were analyzed. Male rats were orally dosed with diazinon (40 mg.L-1), diazinon (40 mg.L-1) +selenium (5 mg.L-1), diazinon (40 mg.L-1) +cadmium (30 mg.L-1), and diazinon (40 mg.L-1) +selenium (5 mg.L-1) +cadmium (30 mg.L-1) in drinking water. After 90 days of per oral administration of compounds, the samples of liver, kidney, muscle tissue (m. quadriceps femoris), and adipose tissue were collected. The content of DZN was analyzed using Gas Chromatography - Mass Spectrometry (GC-MS), Cd was analyzed using an Electrothermal Atomic Absorption Spectrometry (ETAAS) and Se using a Hydride Generation Atomic Absorption Spectrometry (HG-AAS) methods. Cadmium significantly increased in liver and kidney after DZN +Cd and DZN +Se +Cd administration. Se significantly increased in liver of DZN +Se, DZN +Se +Cd and DZN +Cd exposed rats, in kidney of DZN +Se and DZN +Se +Cd and DZN +Cd, and in muscle of DZN +Se +Cd group. Highest DZN content was found in the adipose tissue in DZN, DZN +Cd and DZN +Se +Cd but not in combined exposure with Se. Anyway, the differences between the control and experimental groups were not significant. The results indicate that cadmium and selenium accumulate mainly in liver, kidney and selenium also in muscle after p.o. administration but diazinon concentrations increases were not signifcant. The co-administration of diazinon, Se and Cd affects the content of these compounds in the organism and the accumulation rate depends on the combination of administered compounds. Diazinon and cadmium could contribute to the selenium redistribution in the organism after the peroral intake.

ACCUMULATION of insecticides in tissues and excretion in milk.

ACCUMULATION of insecticides in tissues and excretion in milk.

Detection and determination of organophosphorus insecticides in tissues by thin-layer chromatography

The toxicological analysis of 12 common organophosphorus insecticides is described. Suitable methods for the extraction of organophosphorus insecticides from tissues are proposed. The detection, identification and estimation of these insecticides by thin-layer chromatography is described for 25 solvent systems and a series of chromogenic reagents. The distribution of insecticides in human body tissues in five cases of poisoning by ethyl parathion, malathion, dimethoate, sumithion and phosphamidon has also been studied.

Aldrin and dieldrin uptake in insecticide-resistant and susceptible mosquitofish (Gambusia affinis).

Insecticide-resistant and susceptible mosquitofish (Gambusia affinis) were exposed to14C-aldrin and14C-dieldrin for timed intervals. Whole body and tissue levels of the two organochlorine insecticides were compared between the two populations. At the 10 ppb aldrin and dieldrin treatment levels there were no significant insecticide level differences between resistant and susceptible fish. However, at 80 ppb aldrin and 30 ppb dieldrin there were significant differences. There was 8.5 times as much aldrin in whole body samples of susceptible fish as in whole body samples from resistant fish. There was only 1.24 times as much dieldrin in susceptible as in resistant fish, but it was significant (P<0.05). There were significantly higher amounts of both insecticides in tissues (muscle, liver, and brain) examined from susceptible fish, with the exception of the liver in which dieldrin levels were essentially the same for both populations. Insecticide level comparisons were also made on the basis of whether the fish were exhibiting symptoms of poisoning or not exhibiting symptoms of poisoning. Within the susceptible population there was no difference in the aldrin whole body levels between those fish not exhibiting symptoms and those exhibiting symptoms of poisoning. However, there was a higher level of dieldrin in fish exhibiting symptoms as compared to those not exhibiting symptoms. There were no differences in the insecticide levels in tissues. In comparisons between populations there were significantly higher levels in both whole body and tissue samples of susceptible fish as compared to resistant fish. This was true regardless of whether susceptible fish were exhibiting symptoms or not exhibiting symptoms of poisoning.

Residues of Dursban® Insecticide in Tissues from Turkeys Confined on Soil Treated for Chigger Control12

Studies were conducted to provide data on the extent of residues of Dursban®insecticide (O, O-diethyl 0-(3,5,6- trichloro-2-pyridyl) phosphorothioate) in turkey tissues following confinement on soil treated with either an emulsify able, granular, or wet table powder formulation of the insecticide at 4.5 pounds active chemical per acre. Electron-capture gas chromatography with silicic acid cleanup was used for analysis of samples. Low-level residues of the insecticide were detectable in the skin and fat tissue samples at each sacrificing interval, ranging from 0.01-0.07 ppm at 7 days, and dropping to <0.01-0.02 ppm after 14 days. Residues in mixed muscle and liver tissues were less than 0.01 ppm, the sensitivity level, at each sampling period from turkeys confined on each treated soil.

Depletion of DDT from Commercial Layers ,

INTRODUCTIONTHE use of DDT and other pesticides to control flies, insects, etc., in poultry houses is a common practice. In addition, DDT and other pesticides are recommended for use in feed grain production (U.S.D.A., 1965). Unless the most careful application of these chemicals is accomplished, some will inadvertently get into the feed and/or water, and will result in a residual buildup in the eggs and meat. Various workers (Naber and Ware, 1961; Liska, et al., 1964; Stadelman et al., 1965) have reported residues of chlorinated insecticides in tissues and eggs of chickens exposed to these insecticides.Recent attention focused on DDT residues in eggs has resulted in condemnation of several lots of eggs by government agencies in the midwest and other areas of the U.S. Though pesticide residues in meat and eggs may be a potential human health hazard, no tolerance level has as yet been set by the …

Persistence of Chlorinated Hydrocarbon Insecticide Residues in Chicken Tissues and Eggs

INTRODUCTIONVARIOUS research workers Naber and Ware (1961), Draper et al. (1950, 1952) Ivey et al. (1961) and Liska et al. (1964) have reported residues of chlorinated insecticides in tissues and eggs of chickens exposed to these insecticides. This exposure can occur through spraying of the environment or through consumption of feed which contains insecticide residues.The producer has direct control over the use of sprays in the environment of the chickens. He may, however, purchase considerable amounts of feed of unknown history. Liska et al. (1964) reported that small residues present in feed caused significant residues in tissues and eggs. More information is needed on the persistence of chlorinated insecticides in the tissues and eggs of chickens consuming low levels of insecticides for a short period of time as might be the case from a shipment of contaminated feed.This research was performed to determine the length of time…