This study analyzed how the level of change in China’s industrial structure affected the technological innovation of companies. After China’s accession to the WTO (2001) and the global financial crisis in 2008, the internal and external economic environment has changed, and the subject of rapid economic growth and the level of change in China’s industrial structure and its accompanying impact has become the subject of research by scholars at home and abroad.
 This study classified industrial structure changes into industrial structure rationalization and industrial structure advancement, and then verified the degree of optimization of industrial structure changes. Industrial structure rationalization is an indicator that measures the level of aggregation between industries. It reflects the degree of balanced development among industries and the degree of rational allocation of resources, and evaluates the degree of balance between factor input and output. Industrial structure upgrading is an indicator that evaluates the degree of optimization of industrial structure restructuring. Both industrial structure rationalization and industrial structure upgrading affect and are influenced by economic growth and ripple effects between industries, as well as being influenced by the local economy.
 In this study, a Stata regression analysis was conducted using panel data from 30 provinces, municipalities and autonomous regions in China during the period 2009-2020. In this study, general effect model, mixed effect model, fixed effect model, random effect model, and 2SLS test were compared and analyzed, and the results were compared and analyzed by dividing the region into eastern and coastal regions and inland regions. In addition, verification was conducted by adding variables as key factors influencing technological innovation.
 As a result of the study, it was found that the level of industrial structure rationalization did not have a significant impact on the technological innovation of companies in the eastern and coastal areas, and in the inland area, technology content was relatively low or small and medium-sized enterprises were mainly distributed, so only specific industries affected only technological innovation. appeared to affect As for the level of advanced industrial structure, there is a lot of input into innovative technologies for leading industries in the eastern and coastal regions, which are relatively developed regions, but all of these innovative technologies have not been achieved in sales output or the effects due to the time lag have not yet appeared. appeared to be There are many industries with low technology content in Banman and inland areas, and it is found that technological innovation of companies leads well to sales output.