In recent years, the escalating effects of climate change on surface water bodies have underscored the critical importance of analyzing streamflow trends for effective water resource planning and management. This study conducts a comprehensive regional investigation into the streamflow rate trends of 18 rivers across the United Kingdom (UK). An enhanced Mann-Kendall (MK) test was employed to meticulously analyze both rainfall and streamflow trends on monthly and annual scales. Additionally, the Innovative Trend Analysis (ITA) method was applied to elucidate the variability of streamflow rates, providing a more nuanced understanding of hydrological changes in response to climatic shifts. MK test reveals statistically significant positive trends in streamflow rates, particularly for rivers in south-central Scotland and northern England. Specifically, in January, rivers such as the Tay at Ballathie, Tweed at Peebles, and Teviot at Ormiston showed Z-scores above 2. Annually, similar positive trends were observed, with the Tay at Ballathie (Z = 3.42) and Nith at Friars Carse (Z = 3.35) exhibiting the highest increases in streamflow rates. The ITA method showed no relevant trends for the lowest values of streamflow, except for the Thames at Kingston, while considerable variability was observed for the highest streamflow rates, with several rivers showing positive trends and, however, some England rivers, like Bure at Ingworth, Test at Broadlands, and Trent at Colwick, showing negative trends. From this perspective, a more in-depth analysis of the extreme streamflow trends was carried out. In particular, the flood frequency of the maximum annual streamflow was assessed, based on the fitting of the Generalized Extreme Value (GEV) distribution on the annual maxima. Increasing location parameter (μ) and return period trends were observed for several rivers across the UK. In particular, the Tay at Ballathie (Scotland) showed the most marked increase, with μ that ranged from about 730 m3/s to more than 900 m3/s. At the same time, slight decreasing trends were observed for the Trent River (μ from 378 m3/s to 341 m3/s). The critical comparison of the MK test, ITA, and GEV distribution fitting revealed both agreements and discrepancies among the methods. While the analyses generally aligned in detecting significant trends in streamflow rates, notable discrepancies were observed, particularly in rivers with negligible trends. These inconsistencies highlight the complexity of hydrological responses and the limitations of individual methods. Overall, the study provides a comprehensive view of how streamflow dynamics are evolving in UK rivers, highlighting regional variations in the impact of climate change. This understanding can improve water resource management strategies by integrating diverse analytical approaches.