Development Of Innovative Strategies Research Articles

Influenza A as a True Zoonotic Pathogen: Transmission through Reservoir Hosts

Influenza A virus (IAV) represents a considerable global health threat due to its rapid mutation rates and broad host range, facilitating cross-species transmission and enabling the virus to evade immune defenses. This review explores the molecular mechanisms underlying IAV's pathogenicity, focusing on its zoonotic potential through reservoir hosts, such as wild birds and swine. The virus's ability to undergo antigenic shift and drift allows it to continually adapt to new hosts and environments, posing challenges for control and treatment. Current antiviral therapies are limited by the emergence of resistant strains, underscoring the necessity for innovative vaccine development and treatment strategies. By examining IAV's molecular evolution, immune evasion tactics, and transmission dynamics, this review highlights the critical need for enhanced surveillance, improved therapeutic options, and international cooperation to mitigate future outbreaks. A deeper understanding of these processes is essential to inform public health efforts and combat the persistent threat of IAV.

Radiation-Induced Macrovessel/Microvessel Disease.

Radiation therapy (RT) is a cornerstone in cancer treatment (used in 50% of cases), yet challenges persist because damage to normal tissue through direct impact of radiation or bystander effects is inevitable. Injury of macrovessels by RT manifests as obstructive disease, which is akin to atherosclerotic disease. Historically observed in coronary arteries of patients treated for breast cancer and lymphoma, it also affects patients receiving contemporary therapy for lung and chest cancers. Moreover, radiation at various sites can lead to peripheral vascular disease. An aspect of radiation-induced injury that has received little attention is microvascular injury, which typically results from damage to the endothelium and is considered the primary driver of RT-induced toxicity in the skin, kidney, and brain. This review delves into the clinical manifestations of RT-induced vascular disease, signaling pathways, cellular targets affected by radiation injury, and preclinical models of RT-induced vascular injury. The goal is to inspire the development of innovative strategies to prevent RT-related cardiovascular disease.

CONCEPT AND CHARACTERISTICS OF CUSTOMS AUTHORITIES’ COMPETENCE IN THE CONTEXT OF INNOVATIVE PROCESSES IN UKRAINIAN CUSTOMS AFFAIRS

This article analyzes the concept and characteristics of customs authorities’ competencies in Ukraine within the context of ongoing innovations in customs practices. As Ukraine pursues its Euro-integration goals — aimed at modernizing economic infrastructure, overcoming technological lag, attracting foreign investments, and enhancing international competitiveness — customs authorities play a pivotal role in ensuring the effective functioning of foreign economic activities. The focus of the article is on the necessity to modernize the competencies of customs authorities in line with global standards and to implement advanced innovative technologies, as outlined in Ukraine’s Innovation Development Strategy up to 2030. It examines the impact and significance of innovations such as the ‘Single Window’ system, ‘Smart Customs’ initiatives, pre-arrival cargo information technologies radio-frequency identification (RFID), and blockchain for enhancing customs control, management, and interactions with external partners. A central issue discussed in the article is the development of new competencies required for the effective implementation of these innovations by customs authorities. Specifically, it addresses the need to cultivate digital, intellectual, partnership, and security skills. The article also explores the effects of economic and political instability, particularly the wartime conditions in Ukraine, on the implementation of innovations in customs operations. Key challenges are identified, such as difficulties in exporting high-tech goods, granting incentives for importing innovative equipment, and applying non-tariff regulatory measures, including certification, quotas, and licensing. Recommendations are provided for improving the organizational structures of customs authorities and updating the legal and regulatory framework to adapt to modern requirements and standards. The article advocates for the development of a new, intelligent customs system that can swiftly and effectively respond to changes by employing cutting-edge digital technologies and security methods. Emphasis is placed on the importance of enhancing the qualifications of customs professionals, which is essential for the successful implementation of innovations in customs control.

Customs competencies in ukraine: embracing innovation for enhanced efficiency

This article provides a comprehensive analysis of the concept and features of the competencies of Ukrainian customs authorities considering ongoing innovations in the customs sector. As Ukraine follows its Euro-integration path, aimed at modernizing its economic infrastructure, addressing technological gaps, attracting foreign investments, and enhancing its international competitiveness, the role of customs authorities becomes vital in facilitating effective foreign economic activities. The article underscores the critical need to update the competencies of customs authorities to meet global standards and incorporate advanced innovative technologies, as envisioned in Ukraine’s Innovation Development Strategy up to 2030. It explores the impact and relevance of innovations such as the ‘Smart Customs’ initiatives, ‘Single Window’ system, pre-arrival cargo information systems, radio-frequency identification, and blockchain technology in improving customs control, management, and interactions with external partners. A major focus of the article is on the new competencies required by customs authorities to successfully implement these innovations. It highlights the importance of developing digital, intellectual, partnership, and security skills. Furthermore, the article examines the effects of economic and political instability, particularly the ongoing conflict in Ukraine, on the innovation processes within customs operations. It identifies significant challenges such as the difficulties in exporting high-tech goods, offering incentives for the import of innovative equipment, and the application of non-tariff regulatory measures, including certification, quotas, and licensing. The article provides detailed recommendations for enhancing the organizational structures of customs authorities and calls for updating the legal and regulatory framework to align with current demands and standards. It advocates for the creation of a modern, intelligent customs system that can rapidly and effectively adapt to changes using state-of-the-art digital technologies and security methods. Emphasis is placed on the necessity of enhancing the qualifications of customs professionals, which is deemed essential for the successful integration of innovations in customs control.

Development and activation of the innovative potential of the Russian economy: regional features, structural priorities, levels of implementation

Relevance. The idea of developing and implementing innovative solutions in various spheres of society implies the existence of ways to find such solutions, their active use and improvement. For this reason, the essence of innovative thinking on the scale of both a single enterprise and the state as a whole requires appropriate provision.The purpose of the research is a comprehensive analysis of the chronological cross-section of the level of innovative development of the subjects of the Russian Federation in the context of multiple global economic and political crises and the internal activation of strategic innovative trends in the formats of lawmaking and modernization.Objectives. To achieve this goal, within the framework of this study, the current legislative situation regarding the state's innovation policy and its projected consequences were considered; the factors of growth in the level of innovative development of the regions of the Russian Federation in the context of statistical dominants were studied; the complex results of regional innovation activity and the all-Russian state of the innovative sphere of development, production, export and import of goods and services were analyzed.Methodology. The methodological basis of this study is the method of chronological extrapolation analysis of trends with constant adjustment in conditions of the selective nature of the analytical data bank; in addition, a theoretical generalization of the indexed result and a priori trend forecasting within the observation period are used.Results. The general principles of the innovation segment development are the same for the whole state, but their applicability in different regions depends on the degree of their convergence with border territorial entities — the basis of the innovation development strategy is the assessment of regional potential in the sum of all indicators. Nevertheless, there is always the possibility of finding a thematic statistical trend.Conclusions. It is fundamentally important for the innovative development of the state to take into account the specifics of each individual region. With all the variety of means and methods of innovative development at all levels of management, priority is given to only a few. In this case, rating systems are an auxiliary element of management structures.

The Impact of Innovation, Circular Economy and Sustainable Development Strategies Aimed at Low-carbon Economy on Brazilian Business Performance

The Impact of Innovation, Circular Economy and Sustainable Development Strategies Aimed at Low-carbon Economy on Brazilian Business Performance

Mesoporous cerium oxide nanoenzyme for Efficacious impeding tumor and metastasis via Conferring resistance to anoikis

Tumor cells can survive when detached from the extracellular matrix or lose cell-to-cell connections, leading to a phenomenon known as anoikis resistance (AR). AR is closely associated with the metastasis and proliferation of tumor cells, enabling them to disseminate, migrate, and invade after detachment. Here, we have investigated a novel composite nanoenzyme comprising mesoporous silica/nano-cerium oxide (MSN-Ce@SP/PEG). This nanoenzyme exhibited satisfactory catalase (CAT) activity, efficiently converting high levels of H2O2 within tumor cells into O2, effectively alleviating tumor hypoxia. Furthermore, MSN-Ce@SP/PEG nanoenzyme demonstrated high peroxidase (POD) activity, elevating reactive oxygen species (ROS) levels and attenuating AR in hepatocellular carcinoma (HCC) cells. The MSN-Ce@SP/PEG nanoenzyme exhibited satisfactory dual bioactivity in CAT and POD and was significantly enhanced under favorable photothermal conditions. Through the synergistic effects of these capabilities, the nanoenzyme disrupted the epithelial-mesenchymal transition (EMT) process in detached HCC cells, ultimately inhibiting the recurrence and metastasis potential of anoikis-resistant HCC cells. This study represents the first report of a novel nanoenzyme based on mesoporous silica/nano-cerium oxide for treating AR in HCC cells, thereby suppressing HCC recurrence and metastasis. The findings of this work offer a pioneering perspective for the development of innovative strategies to prevent the recurrence and metastasis of HCC.

Functional analyses of dopamine receptors involved in virus transmission and reproduction in the small brown planthopper Laodelphax striatellus

Dopamine (DA) is the most abundant biogenic amine present in the insect central nervous system, and regulates multiple functions in physiology and behaviors through dopamine receptors (DARs). The small brown planthopper Laodelphax striatellus is an important agricultural pest and causes serious damage by transmitting diverse plant viruses, such as rice stripe virus (RSV). However, DARs have not yet been molecularly characterized in planthoppers, and their roles in virus infection and transmission remain largely unknown in insect vectors. In this study, we cloned four LsDARs (LsDOP1, LsDOP2, LsDOP3 and LsDopEcR) from L.striatellus. LsDARs share considerable sequence identity with their orthologous DARs, and cluster nicely with their corresponding receptor groups. The transcript levels of LsDARs varied in different developmental stages and adult tissues, with the highest expressions in the egg stage and in the brain. The expression levels of LsDARs were significantly higher in RSV-viruliferous L.striatellus. Knockdown of LsDOP2 and LsDOP3 significantly downregulated the expressions of viral genes of capsid protein (CP) and RNA3 segment (RNA3), while LsDOP1 knockdown upregulated their expressions. Silencing LsDopEcR upregulated and then downregulated CP and RNA3 expressions. Moreover, LsDOP2 and LsDOP3 knockdown significantly decreased the vertical transmission rates of RSV. Meanwhile, DA injection promoted RSV transmission and accumulation. We further demonstrated that silencing of LsDARs significantly altered the expressions of vitellogenin (LsVg) and Vg receptor (LsVgR). Furthermore, the reproduction performance of L.striatellus was reduced by LsDOP2 and LsDOP3 knockdown, but increased by LsDopEcR knockdown, and not affected by LsDOP1 silencing. These results provide critical information concerning the roles of DARs in virus transmission and reproduction in L.striatellus, and open the way for the development of innovative strategies for planthopper control.

Innovative potential of business environment development in the virtual market at the digitalization stage

Subject. The article discusses the innovation potential of business environment development. Objectives. The aim is to explore the innovative capacity of business environment development in the virtual market at the stage of digitalization. Methods. The study employs research methods, like comparative, dialectical cognition, scientific abstraction, morphological analysis, synthesis, and theoretical generalization. Results. We systematized preferential characteristics of the virtual market, which consist in large-scale opportunities for promoting marketing innovations in the market of goods and services. The paper defines the role of the virtual market, foundations of the formation of business environment, characterizes innovations of virtual markets, considers the main aspects of digitalization of virtual markets, strategies for innovative development, technologies for the development of innovative capacity of business environment in the virtual market. Conclusions. The digitalization of virtual markets changes the way of doing business, delivering products, and interacting with customers. It requires companies to be flexible, able to adapt quickly to new technologies, and remain competitive. Depending on the degree of readiness, companies need to create and implement various strategies that include transferring customers to the digital space, as well as digital transformation strategies.

THE ROLE OF INNOVATION STRATEGY IN ENSURING SUSTAINABLE DEVELOPMENT OF THE ENTERPRISE

The article discusses the role of innovation strategy in ensuring sustainable development of the enterprise. At this stage of economic development, organizations are provided with a huge number of opportunities that can be used to develop entrepreneurial activity. Rapid changes in the external and internal environment contribute to the fact that enterprises have to adapt to new conditions, as well as develop strategies for innovative business development. In this regard, the ability to develop innovative strategies is becoming a key competency that allows you to competently manage an enterprise. Competition between companies is becoming more intense, only enterprises that can develop the most effective innovative strategies will be able to take and maintain leadership positions. The role of innovation is manifested in ensuring the success of business in the long term. Innovations contribute to increasing the competitive position of the organization. Innovative strategy allows companies to take their business to a new level. It defines promising areas of development of the company, assesses its innovative potential and level of investment attractiveness, allows you to establish new areas of cooperation, helping the business to remain competitive. The development of an effective innovation strategy will allow the company to take a leadership position that will allow it to stay in today's highly competitive world. Industrial development is a priority sector for any state. Industry ensures the country's independence from a number of imported goods, provides jobs, and promotes economic stability. Any developed state will take measures to develop industry. But the industrial sector is quite complex for doing business, because it requires significant resources at the start of work, a set of skills and knowledge, and a high level of technical equipment. Against the background of the importance of the industrial sector for the life of the state as a whole and the complexity of implementing entrepreneurial tasks in this area, the formation of a concept for the sustainable development of industrial enterprises is of particular relevance. The constituent components of the sustainable development of industrial enterprises should be ensured both at the macro and micro levels. Financial and economic components of the sustainable development of industrial enterprises at the macro level imply the presence of the following factors. Ensuring the investment attractiveness of the country. Attracting foreign investors is one of the ways to ensure the sustainable development of industrial enterprises, as well as the growth of the state's economy. Development of an appropriate monetary and credit policy. A number of factors influence the sustainable development of industrial enterprises: the level of inflation, the availability of credit resources, the volume of money circulation. In the absence of effective mechanisms for maintaining stability in the monetary and credit sphere, the implementation of the directions of the concept of sustainable development of industrial enterprises is also impossible. Thus, sustainable development of industrial enterprises is one of the most important areas of work of the state authorities. The concept of sustainable development of industrial enterprises includes a number of components, some of which are already being actively implemented. Also, the concept of sustainable development of industrial enterprises should include a number of measures that contribute to increasing the profitability of the company's activities and take into account the specifics of its activities. Keywords: innovation, innovation process, innovative development, innovation strategy, enterprise, strategic management, competitiveness.

Enterprise Innovation and Sustainable Development Strategy in the Era of Digital Economy

Enterprise Innovation and Sustainable Development Strategy in the Era of Digital Economy

Some issues of public administration of education and science

Problem setting. The essential globalization changes require new approaches to the management of the educational sphere, which is an integral set of educational structures, relations, activities and consciousness that ensures the reproduction and development of the intellectual potential of society. At the same time, it is necessary to ensure an optimal ratio of newly introduced elements with traditional ones intended for the management of an educational institution. Analysis of recent researches and publications. The article mainly analyzes the provisions of Ukraine’s regulatory legal acts. Among domestic scholars, attention is drawn to the works of: V. E. Khoustova, O. I. Reshetnyak, V. A. Zinchenko, M. V. Kryvanych, I. V. Borisov. Purpose of research is to examine the legal regulation of the system of public administration of education and science at the conceptual level. Article’s main body. The draft Strategy of Innovative Development of Ukraine for 2010-2020 in the context of globalization challenges envisaged the need to reform the management of science and innovation and the need to create a new government body the Ministry of Science and Innovative Development, which would play a coordinating role in the scheme of innovation development management. The newly created ministry would have to formulate state scientific, technological and innovation programs that would be implemented in the interests of all ministries and departments, control and direct budget funds to the scientific, technological and innovation sphere, organize an examination of the effectiveness of scientific teams. Conclusions and prospects for the development. The state has experience in the establishment and functioning of an independent central executive body directly accountable to the Cabinet of Ministers of Ukraine, so the proposal for the functioning of such a specialized body is considered to be worthy of support and is quite possible to implement (using this experience with appropriate adaptation to current global challenges and improvement of certain provisions). In our opinion, the main drawback that contributed to the liquidation of the state committee was the lack of a systematic combination of the powers of the committee and the NAS of Ukraine in the field of science. 2. Specialized bodies for the development of science and innovation in Europe play a crucial role in the development of scientific research, technology and innovation, provide funding and support for scientific and technological projects, contributing to economic growth and social progress, so it is important to adopt this experience to ensure optimization of the management of science and education in Ukraine.

Initial insights from Innovation Strategy development in Wales

This paper presents insights from emerging work to support the development of a Culture of Innovation in Wales. The region has been subject of much public policy debate, not least for Innovation Policy during the 20 years since a previous Welsh Government Innovation Strategy. This work focuses on how innovation culture intersects with government policy to develop and implement the Innovation Strategy across all sectors of WG responsibility. The co-production approach adopted by WG presents an open approach to public policy, informed through written submissions, public events, and other stakeholder-specific fora. Drawing upon themes from academic literature and those identified and explored through the consultation, the paper explores the level of alignment between stakeholders and the potential actions to enhance conditions for innovation within Wales. The Wellbeing of Future Generations (Wales) Act 2015 provides a unique context for this work, which resonates with the United Nations Sustainable Development Goals. It forms part of a broader and longer-term study intended to support the refinement and delivery of the Innovation Strategy.

Innovation meets modest fashion-based localism: A systematic literature review

Research on innovation, localism, and modest fashion has garnered significant scholarly attention in recent years. However, existing studies have not produced conclusive results regarding the link between innovation in modest fashion and localism. This systematic literature review aims to identify research trends, theories, and innovations in modest fashion and determine factors related to innovation in modest fashion on the basis of localism. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method was used to analyze 24 articles on innovation, localism, and modest fashion from the Scopus, Web of Science, and ProQuest databases. The results indicate a growing trend in the themes of innovation, localism, and modest fashion over the last decade. Additionally, six main factors have emerged to answer the research question regarding the determinants of innovation: design-driven, market-driven, technology-driven, localism-driven, culture-driven, and sustainability-driven. These factors emphasize the significance of considering localism and sustainability in shaping future innovations in the modest fashion industry. The study concludes that the combination of these driving factors can greatly influence the development of innovative strategies that align with consumer preferences and global market trends. Moreover, the findings of this review contribute to the growing body of knowledge on the relationship between innovation and localism, offering practical insights for business leaders and policymakers. By understanding how localism can drive innovation in the modest fashion industry, businesses can better position themselves to create sustainable and competitive advantages. Future research should focus on further exploring these factors to provide more in-depth insights into the role of localism in promoting innovation and business performance in the modest fashion sector.

Formation of Nanofibrillar Self-Healing Hydrogels Using Antimicrobial Peptides.

The rise of drug-resistant microorganisms has prompted the development of innovative strategies with the aim of addressing this challenge. Among the alternative approaches gaining increased attention are antimicrobial peptides (AMPs), a group of peptides with the ability to combat microbial pathogens. Here, we investigated a small peptide, KLVFF, derived from the Alzheimer's amyloid-β (Aβ) protein. While Aβ has been associated with the development of neurodegenerative diseases, the core part of the Aβ protein, namely the Aβ 16-20 fragment, has also been exploited to obtain highly functional biomaterials. In this study we found that KLVFF is capable of self-assembling into a fibrillar network to form a self-healing hydrogel. Moreover, this small peptide can undergo a transition from a gel to a liquid state following application of shear stress, in a reversible manner. As an AMP, this material exhibited both antibacterial and antifungal properties while remaining highly biocompatible and noncytotoxic toward mammalian cells. The propensity of the KLVFF hydrogel to rapidly assemble into highly ordered macroscopic structures makes it an ideal candidate for biomedical applications necessitating antimicrobial activity, such as wound healing.

The Future Possible Distribution of Kasnak Oak (Quercus vulcanica Boiss. & Heldr. ex Kotschy) in Anatolia under Climate Change Scenarios

The deterioration of natural habitats for oak species has steadily occurred as a consequence of both climate change and human pressure. Therefore, detailed and reliable information about the geographic distribution of oak species under changing climate conditions is needed for diverse ecological and conservation practices. This study examined the habitat suitability of endemic Kasnak oak, Quercus vulcanica Boiss. & Heldr. ex Kotschy, an endemic that ranges across the Central Anatolia Region and surrounding mountains in Türkiye. The occurrence data were gathered through fieldwork, and new records were identified. Next, we applied ecological niche modeling to assess the past, present-day, and future potential geographic range of the species in Anatolia. Projections for the Last Glacial Maximum indicate that most of the suitable areas for Kasnak oak were in southern Anatolia. However, present-day estimates suggest projections estimate suitable habitats in northern Anatolia and around the Anatolian Diagonal. According to future projections, the distribution of the species seems to decrease by 2100, with habitat suitability reduction ranging from 3.27% to 7.88%. Projections suggest a decrease in habitat suitability for the species, particularly in the western and southern Türkiye in the future. Moreover, the projections indicated that suitable habitats for the northern range of the species would likely persist until 2100, although they would diminish towards the northeast. The results can be effectively applied to enhance biodiversity conservation planning and management, leading to the development of innovative strategies.

Immunotherapeutic advances in glioma management: The rise of vaccine-based approaches.

Gliomas, particularly glioblastoma multiforme (GBM), are highly aggressive brain tumors that present significant challenges in oncology due to their rapid progression and resistance to conventional therapies. Despite advancements in treatment, the prognosis for patients with GBM remains poor, necessitating the exploration of novel therapeutic approaches. One such emerging strategy is the development of glioma vaccines, which aim to stimulate the immune system to target and destroy tumor cells. This review aims to provide a comprehensive evaluation of the current landscape of glioma vaccine development, analyzing the types of vaccines under investigation, the outcomes of clinical trials, and the challenges and opportunities associated with their implementation. The goal is to highlight the potential of glioma vaccines in advancing more effective and personalized treatments for glioma patients. This narrative review systematically assessed the role of glioma vaccines by including full-text articles published between 2000 and 2024 in English. Databases such as PubMed/MEDLINE, EMBASE, the Cochrane Library, and Scopus were searched using key terms like "glioma," "brain tumor," "glioblastoma," "vaccine," and "immunotherapy." The review incorporated both pre-clinical and clinical studies, including descriptive studies, animal-model studies, cohort studies, and observational studies. Exclusion criteria were applied to omit abstracts, case reports, posters, and non-peer-reviewed studies, ensuring the inclusion of high-quality evidence. Clinical trials investigating various glioma vaccines, including peptide-based, DNA/RNA-based, whole-cell, and dendritic-cell vaccines, have shown promising results. These vaccines demonstrated potential in extending survival rates and managing adverse events in glioma patients. However, significant challenges remain, such as therapeutic resistance due to tumor heterogeneity and immune evasion mechanisms. Moreover, the lack of standardized guidelines for evaluating vaccine responses and issues related to ethical considerations, regulatory hurdles, and vaccine acceptance among patients further complicate the implementation of glioma vaccines. Addressing the challenges associated with glioma vaccines involves exploring combination therapies, targeted approaches, and personalized medicine. Combining vaccines with traditional therapies like radiotherapy or chemotherapy may enhance efficacy by boosting the immune system's ability to fight tumor cells. Personalized vaccines tailored to individual patient profiles present an opportunity for improved outcomes. Furthermore, global collaboration and equitable distribution are critical for ensuring access to glioma vaccines, especially in low- and middle-income countries with limited healthcare resources CONCLUSION: Glioma vaccines represent a promising avenue in the fight against gliomas, offering hope for improving patient outcomes in a disease that is notoriously difficult to treat. Despite the challenges, continued research and the development of innovative strategies, including combination therapies and personalized approaches, are essential for overcoming current barriers and transforming the treatment landscape for glioma patients.

Performance Research of Chinese Patent Medicine Enterprises to Innovative Medicine Research and Development Strategy Transformation

Performance Research of Chinese Patent Medicine Enterprises to Innovative Medicine Research and Development Strategy Transformation

Personalized Dendritic-cell-based Vaccines Targeting Cancer Neoantigens.

Cancer immunotherapy activates the host immune system against tumor cells and has the potential to lead to the development of innovative strategies for cancer treatment. Neoantigens are non-self-antigens produced by genetic mutations in tumor cells that induce a strong immune response against tumor cells without central immune tolerance. Along with advances in neoantigen analysis technology, the development of vaccines focusing on neoantigens is being accelerated. Whereas there are various platforms for neoantigen vaccines, combined immuno-therapies are being developed simultaneously with the clinical application of synthetic long peptides and mRNA and dendritic-cell (DC)-based vaccines. Personalized DC-based vaccines not only can load various antigens including neoantigens, but also have the potential to elicit a strong immune response in T cells as antigen-presenting cells. In this review, we describe the properties of neoantigens and the basic characteristics of DCs. We also discuss the clinical applications of neoantigen vaccines, focusing on personalized DC-based vaccines, as well as future research and development directions and challenges.

The Analysis of Electric Phase Separation and Common Technical Issues of High-speed Railway System in China

The electric railway, as a vital economic transportation artery, offers high efficiency and effectiveness compared to other modes of transportation. The characteristics of efficient transport, comfortable ride and environmental friendliness have effectively driven regional economic construction and industrial economy along the route, which has significantly enhanced cultural and economic exchanges between different regions, becomes the preferred mode of transportation for medium-distance and long-distance travel, and plays an irreplaceable role in China’s current transportation system. Under the increasing demand for passenger flow, the high-speed and high-density tracking operation of trains has become the new normal of high-speed railway operation management. In the background of national science and technology innovation development strategy, how to further shorten the train tracking interval to improve transportation efficiency and further reduce the energy consumption of train operation to improve the energy utilization level of the railway industry is the focus of the current electric railway construction and operation management department. The electric phase separation is a special and intricate part of the traction power supply system in China’s electric railway, and it is an indispensable component. The article describes that some main techniques relating to electrical phase separation are utilized extensively in China’s high-speed railway, by studying the technologies of electric phase separation, a few new methods were given and shared, which will solve the issues of high energy consumption, increased breakdowns, large equipment loss, and the lower speed, to better serve economic and social development and people’s travel.