In this piece of communication, a theoretical investigation of two dimensional boundary layer flow of Magnetohydrodynamics (MHD) Carreau nanofluid axisymmetric flow past unsteady radially stretching porous disk is made. The investigation includes the effects of viscous dissipation, Joule heating, thermal radiation, suction/injection, Darcy–Forchheimer porosity model and binary chemical reaction with activation energy, etc. To examine the impacts of the aforementioned effects, the conservation laws are formulated with strongly nonlinear partial differential equations (PDEs), which are then transformed into a system of initial value problems (IVPs) using appropriate similarity transformations and techniques. The 5th order Runge–Kutta with the shooting technique is used to find numerical solutions aided by Python programming with built in program “fsolve”. The method is validated with other published articles under common assumptions and it agrees nicely. The impacts of the pertinent parameters on velocity, temperature, concentration, skin friction coefficient and the rates of mass and heat transfers with in the flow regime are displayed using graphs and tables. The main outcomes include the motivation of local Nusselt and Sherwood numbers for shear thickening (n=1.5) than shear thinning (n=0.5) cases of the Carreau nanofluid. The momentum boundary layer of the Carreau nanofluid gets thinner with an increase in Forchheimer number, unsteady and suction parameters. A dual nature is observed for concentration of the Carreau nanofluid with a rise in Eckert number, i.e increasing in concentration around the wall and decreasing far away from the wall. The rise in destructive and constructive chemical reaction parameters disperse and accumulate the concentration of the system, respectively.