Abstract This study uses fixed buoy time series to create an algorithm for sea surface temperature (SST) cooling underneath a tropical cyclone (TC) inner core. To build predictive equations, SST cooling is first related to single variable predictors such as the SST before storm arrival, ocean heat content (OHC), mixed layer depth, sea surface salinity and stratification, storm intensity, storm translation speed, and latitude. Of all the single variable predictors, initial SST before storm arrival explains the greatest amount of variance for the change in SST during storm passage. Using a combination of predictors, we created nonlinear predictive equations for SST cooling. In general, the best predictive equations have four predictors and are built with knowledge about the prestorm ocean structure (e.g., OHC), storm intensity (e.g., minimum sea level pressure), initial SST values before storm arrival, and latitude. The best-performing SST cooling equations are broken up into two ocean regimes: when the ocean heat content is less than 60 kJ cm−2 (greater spread in SST cooling values) and when the ocean heat content is greater than 60 kJ cm−2 (SST cooling is always less than 2°C), which demonstrates the importance of the prestorm oceanic thermal structure on the in-storm SST value. The new equations are compared to what is currently used in a statistical–dynamical model. Overall, since the ocean providing the latent heat and sensible heat fluxes necessary for TC intensification, the results highlight the importance for consistently obtaining accurate in-storm upper-oceanic thermal structure for accurate TC intensity forecasts. Significance Statement The ocean provides the heat and moisture necessary for tropical cyclone (TC) intensification. Since the heat and moisture transfer depend on the sea surface temperature (SST), we create statistical equations for the prediction of SST underneath the storm. The variables we use combine the initial SST before the storm arrives, the upper-ocean thermal structure, and the strength and translation speed of the storm. The predictive equations for SST are evaluated for how well they improve TC intensity forecasts. The best-performing equations can be used for prediction in operational statistical models, which can aid intensity forecasts.