Primary scrotal lipoma is an exceptionally rare finding, typically detected incidentally but posing diagnostic dilemmas when presenting as a substantial mass. Often mistaken initially for inguinal-scrotal hernias or testicular malignancies due to clinical similarities, accurate differentiation is essential for appropriate management. Here, we present a case of a middle-aged male with a massive scrotal swelling, initially raising concerns of malignancy. However, thorough clinical evaluation and imaging studies guided by suspicion for lipomatous origin facilitated the correct diagnosis. Histopathological examination confirmed the presence of a primary scrotal lipoma, highlighting the importance of considering lipomas in the differential diagnosis of scrotal masses. Surgical excision remains the mainstay of treatment to alleviate symptoms, prevent complications, and confirm the benign nature of the lesion. This case underscores the need for heightened awareness among clinicians managing scrotal pathologies to ensure timely diagnosis and effective management strategies in urological practice.
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