PurposeHow does the interplay between entrepreneurship policies and both formal and informal gender equality affect women’s inclination towards self-employment in contrast to men?Design/methodology/approachThis study introduces and validates a comprehensive multi-level model underpinned by symbolic interactionism, institutional theory, and the nuances of gendered institutions. Employing innovative analytical techniques and leveraging data from 66 countries, we scrutinize how formal and informal gendered institutional arrangements either inhibit or facilitate an environment favorable to women’s entrepreneurial activities.FindingsSignificantly, our research delves into the nuanced effects of specific entrepreneurship policies across diverse nations. While these policies can bridge the gendered resource gap, a profound understanding of broader gender dynamics is crucial for fostering an inclusive entrepreneurial landscape.Originality/valueOur insights advocate for a more integrated approach to bolster women’s participation in entrepreneurship, thus furthering their socio-economic progression.