Vegetation can reflect the ecological characteristics of soil, water and temperature, which is of great significance for protecting the ecological environment. Vegetation growth is affected by topographic features such as elevation, slope and aspect. Due to the autocorrelation of topography and vegetation index, the current research does not fully consider the influence of autocorrelation on the relationship between vegetation index and topographic factors. Therefore, it is necessary to eliminate the autocorrelation of topography and vegetation index through topographic correction, so as to truly reveal the relationship between vegetation and topography. Therefore, this study takes the loess hilly region as the research area, and conducts terrain correction based on Landsat8 OIL data to reveal the relationship between vegetation and different terrain factors ( elevation, slope, aspect ). The main contents and conclusions of this paper are as follows: (1) Analyze the spatial distribution of the corrected vegetation index ( NDVI, EVI ) and topographic factors (elevation, slope, aspect ), explore the law between vegetation index and topographic factors. (2) The response of the corrected vegetation index to topographic features tends to be more consistent. With the increase of elevation, it increases first and then decreases, reaching the maximum at 980~990 m. With the increase of slope, it shows a trend of continuous growth, reaching the maximum at 30 ~ 36 °. With the increase of aspect, there is a trend of growth-reduction-growth, reaching the maximum at 65 °.