Industrial Pharmacy Research Articles

EVALUATION OF STUDENTS' TRAINING LEVEL IN THE ELECTIVE DISCIPLINE "QUALITY SYSTEMS IN PHARMACY"

The pharmaceutical industry is rapidly developing and implementing new innovative approaches and legal regulation of the quality management system of medicinal products, which includes a set of methods, processes and resources that are necessary for quality management. Therefore, the study by students of the specialty 226 "Pharmacy, industrial pharmacy" of the elective discipline "Quality systems in pharmacy" is an important area of professional training of a qualified specialist who will master the methodology of quality management, normative-legislative and organizational-economic aspects of quality control of medicinal products at pharmaceutical enterprises. Training of domestic students in the field of drug technology is an important direction of pharmaceutical education today. The main tasks of studying the elective discipline "Quality Systems in Pharmacy" are: formation of students of higher education in general knowledge about the quality indicators of medicinal products according to the stage of their life cycle by fulfilling the requirements of proper pharmaceutical practices and developing documentation in accordance with their requirements; formation of practical skills; raising the level of general and scientific development of students of higher education, forming their outlook and perspective as modern qualified specialists in the field of pharmacy. The purpose of the work was to study the assessment of the level of training of domestic students in the elective discipline "Quality Systems in Pharmacy". Materials and methods. We used an empirical research method (questionnaire). Questionnaire was a key research method, as it allows to get answers from the student audience regarding the organization of the educational process. A survey was conducted to assess the level of preparation of domestic students of the 5th year of the Faculty of Pharmacy who completed the study of the selective discipline "Quality Systems in Pharmacy". 50 full-time students and 2 distance learning students took part in the survey. Out of all the respondents, only one studies on budget forms of education. Research results. According to the curriculum, the elective discipline "Quality Systems in Pharmacy" at the Faculty of Pharmacy of IFNMU is studied in the V course in the IX semester, at the stage when students have already acquired basic knowledge of pharmaceutical disciplines. The discipline is chosen by already formed specialists who possess a large stock of theoretical knowledge and practical skills and are motivated to study a new subject, so it remains for the teacher to systematize information for the proper conduct of the discipline study course. 3 ECTS credits are provided for the study of the discipline in the curriculum. The discipline includes 20 hours of lectures, 30 hours of practical classes, 40 hours of independent student work and ends with a module. Lecture and practical material taught at the level of modern scientific and practical data with the aim of forming students' program results. We conducted an analysis of problems in the organization of the educational process for students of the Faculty of Pharmacy of the Ivano-Frankivsk National Medical University during full-time education. The success of implementing the selective discipline "Quality Systems in Pharmacy" and ensuring a high level of training depends primarily on the quality of the work of scientific and pedagogical workers.

FORMATION OF CONCEPTUAL AND TERMINOLOGICAL APPARATUS AS A COMPONENT OF PROFESSIONALLY ORIENTED FUTURE PHARMACIST TRAINING

The article analyzes the process of forming the conceptual and terminological apparatus as a component of professionally oriented training of future pharmacists; based on generalization of theoretical foundations, the features, strategies, and methods, the formation of the conceptual and terminological apparatus that contribute to the efficient training of future pharmacists in the process of studying the discipline «Analytical Chemistry» are revealed. The following criteria for the selection of chemical terms and concepts are proposed: thematic affiliation (exclusion of terms from related fields), focus on the vocabulary, systematicity, completeness of terminology coverage, as well as synchronicity (time factor), usage (frequency), semantic value of the term, term-forming capacity, normativity, and connectivity. The article considers the holistic organization of work on the qualitative mastering of the terminological vocabulary of analytical chemistry, and the development of professionally oriented communicative competence of future specialists majoring in the specialty 226 «Pharmacy, Industrial Pharmacy». It involves the use of proven methods and techniques for the rational selection, semantization and presentation of terminological language units. The exercises are divided into types, and their sequence in working with terms is established: introduction of terminological vocabulary (preparatory exercises) – language exercises – communicative and linguistic exercises, which involve the simultaneous selection and functioning of pre-text, while-text, and post-text exercises in such work. Post-textual tasks and forms of application of exercises have been developed. They are the following: work in pairs, organizing a cluster based on reference material, sentence construction, terminological dictation, and crossword puzzles. microtext construction, formulating definitions of terms, working with mental maps, using multimedia, trainings, video presentations, and the game «Guess the term!». It has been concluded that the usage of various communicative and speech exercises aimed at mastering terminological vocabulary in the process of teaching analytical chemistry contributes to professional communication skills improvement in the discipline and, by forming terminological experience, increases the level of professional language competence of future pharmacy specialists.

FIP Cape Town 2024: Industrial Pharmacy

Accepted abstracts under the theme: Industrial Pharmacy (n=6)

Raman spectroscopic imaging – practical applications in industrial pharmacy and medical diagnostics: a review.

Currently, Raman imaging as a non-destructive technique providing knowledge on structural characterization of the investigated samples is gaining more and more interest among industrial formulation and process scientists. In the pharmaceutical sector, the creation of novel products and formulations necessitates flexible and adaptable analysis, and increasingly also imaging capabilities. In this paper, the attention is directed toward the research progress, that has occurred in the application of non-invasive Raman chemical imaging techniques in industrial pharmacy and medical diagnostics in recent years. This work aims to explore the potential of Raman imaging as a knowledge discovery method for the non-destructive evaluation of pharmaceutical formulations as well as human cells to support medical diagnostics in clinical practice. A review of the latest scientific papers indicates that the applications of Raman imaging in pharmaceutical sciences and medical diagnostics are diverse and far-reaching from ensuring the quality of pharmaceutical formulations to studying complex drug delivery systems, monitoring manufacturing processes, and medical diagnostics of cancers and other diseases. As technology continues to evolve, the integration of Raman imaging into pharmaceutical and clinical practices is expected to expand, providing new insights and solutions to the challenges faced by the pharmaceutical industry and medical diagnostics.

FEATURES OF THE FOREIGN STUDENTS TRAINING IN THE ELECTIVE DISCIPLINE "QUALITY SYSTEMS IN PHARMACY"

The pharmaceutical industry is rapidly developing and implementing new innovative approaches and legal regulation of the drugs quality management system, which includes a set of process methods and resources that are necessary for quality management. Therefore, the mastery by students of the specialty 226 "Pharmacy, Industrial Pharmacy" of the elective discipline "Quality Systems in Pharmacy" is an important issue of their professional training which will help them to master the methodology of quality management, normative-legislative and organizational-economic aspects of quality control of medicinal products at pharmaceutical enterprises. The elective discipline "Quality Systems in Pharmacy" is closely connected to some other disciplines, such as “Pharmacy and Industrial Technology of Drugs”, and “Technology of Cosmetic Drugs”. Training takes place according to the credit-module system in accordance with the basic requirements of the Bologna Convention.
 The main tasks of the elective discipline "Quality Systems in Pharmacy" are: providing the students with general knowledge about the quality indicators of medicines depending on the stage of their life cycle by fulfilling the requirements of good pharmaceutical practices and developing documentation in accordance with their requirements; formation of practical skills related to the rules and requirements for the creation, manufacture, research, distribution, sale, and storage of medicines in accordance with the requirements of good pharmaceutical practices operating in the European Union; improvement of the level of general and scientific development of students, formation of their outlook and perspective as modern qualified specialists in the field of pharmacy.
 The aim of the research is to study the peculiarities of the training of foreign students of the specialty 226 "Pharmacy, Industrial Pharmacy" in the Ivano-Frankivsk National Medical University (IFNMU) in the elective discipline "Quality Systems in Pharmacy". The subject of study of the discipline "Quality Systems in Pharmacy" is the methodology of pharmaceutical development, the components of the quality assurance system of medicines, including the requirements of the Guidelines of good practices in pharmacy for each stage of the life cycle of a medicinal product. The discipline is usually chosen by the well formed specialists.
 Teaching the elective discipline "Quality Systems in Pharmacy" at the specialty 226 "Pharmacy, Industrial Pharmacy" of IFNMU is necessary for students to thoroughly master the quality management system of medicines, it contributes to the optimization of the educational process and the improvement of the new principle of problem-oriented education of students and its control. This discipline orients students to the importance of the following issues: ensuring the quality of medicines at all stages of their life cycle; regulatory activities in the field of quality control of medicines; implementation of medicines; optimization and monitoring of pharmaceutical quality systems processes. This discipline forms the important competencies, knowledge, skills, abilities, and aspirations of students for self-development, while their teacher also develops and improves in the professional field together with students. Taking into account the trend of the European development of the pharmaceutical industry, the quality management system of medicines also should be harmonized with European standards.

ПРАКТИЧЕСКИЙ ОПЫТ ПРИМЕНЕНИЯ ИНТЕРАКТИВНЫХ ЗАНЯТИЙ В МАГИСТРАТУРЕ «ПРОМЫШЛЕННАЯ ФАРМАЦИЯ»

Education of Master's degree students at the Institute of Pharmacy is carried out under the educational program "Industrial Pharmacy". Training is oriented to practical activity and forms professional competencies. The purpose of training in the Master's program is to learn to control the requirements for the production of medicines in pharmaceutical production, to implement the rules of the pharmaceutical quality system of production and quality control of medicines, to improve the pharmaceutical quality system of production of medicines. The set goals in training are achievable with the introduction of interactive methods in the classroom. Master's degree teacher is obliged not only to be competent in the issues of the discipline he teaches, but also must improve the learning process according to the modern requirement of the time. Interactive learning is characterized by joint activity of students and teacher. One of the interactive teaching methods is a round table. At the round table class the student consolidates the previously acquired knowledge, expands it by supplementing the missing information, learns to solve problems in the course of discussion. For this purpose, the teacher creates comfortable conditions when all students are involved in the learning process, they understand the material of the topic, know it and think about solving the problem posed by the teacher in the class. The study analyzed the experience of conducting an interactive lesson in the form of a round table in the discipline of pharmaceutical chemistry and drug analysis. The authors conducted a questionnaire survey of master's degree students. According to the results of the survey it was found out that the use of interactive methods in the educational process increased the effectiveness of learning for the majority of students. Almost all master's students participated in the discussion at the class, even those who previously behaved passively in learning. The majority of students noted that their uncertainty in front of the audience disappeared, communication with the teacher and other students during the round table facilitated rapid and productive assimilation of the material. The results of the study can be used in the professional activities of university teachers.

The Relevance of Acquiring of Legal Knowledge Concerning Labor Protection, Fire Safety, Sanitary and Epidemiological Regime for Health Care Professionals

The acquisition of legal knowledge pertaining to labor protection, fire safety, and sanitary and epidemiological regime is crucial for healthcare professionals, underscoring a multifaceted relevance in their field. Primarily, such knowledge ensures the safety and well-being of both healthcare workers and patients. Understanding labor protection laws helps healthcare professionals recognize their rights and responsibilities, leading to safer work environments. This knowledge is pivotal in preventing occupational hazards, which are prevalent in healthcare settings, including exposure to infectious diseases, chemical substances, and physical strain. Furthermore, legal knowledge in these areas enhances the professional competency of healthcare workers, promoting a comprehensive approach to patient care and facility management. It empowers healthcare professionals to advocate for better working conditions and patient safety, reflecting their commitment to ethical and legal standards in healthcare. The key aspects of the work program under the normative educational component "Occupational safety and occupational safety in the industry" in the training of specialists of the second (master's) level of higher education in the specialty 226 "Pharmacy, industrial pharmacy", specialization 226.01 "Pharmacy" of the field of knowledge 22 "Health care" were analyzed I". The training of future occupational health and safety specialists is aimed at the formation of professional skills and knowledge necessary for effective work in the modern pharmaceutical environment of occupational safety and health. The study determined the priority directions of the educational process: legislative regulation in the field of labor protection, fire safety, and the sanitary-epidemiological regime in pharmacy. The relevance of acquiring legal knowledge of labor protection, fire safety, sanitary and epidemiological regime by future healthcare sector specialists were substantiated. The presented conclusions and recommendations can serve as a basis for further improvement of the educational process and training of masters who will successfully implement their knowledge in practice, ensuring a high level of safety and efficiency in the pharmaceutical industry.

Exploring Perceptions of Pharmaceutical Vocational High School (VHS) Students toward the Importance of English for Their Future Career

Vocational High Schools (VHS) prepare their students to be ready to work in their fields after graduation. In this globalization era, understanding English will be beneficial and a plus point for the students when looking for a job. Thus, this descriptive qualitative research aimed to explore the perceptions of pharmaceutical VHS students regarding the significance of English for their future careers. The participants, consisting of eight twelfth-grade students who had high English scores and majored in Industrial Pharmacy, were interviewed and the findings revealed that they believed that English proficiency was crucial for their future careers as it helps in accessing international job opportunities and resources, benefiting from professional development and in-house training, and overcoming language barriers in a globalized world. Thus, it is suggested that the English curriculum should be tailored to meet the specific language needs of the pharmaceutical field and future research could explore the expectations of pharmaceutical industry employers regarding the English skills of job applicants.

Understanding and attitude toward upcycling according to the survey of students of various specialities

The attitude to upcycling technologies of undergraduate students of five specialities (design, clothing industry technology, vocational education and training, industrial pharmacy and psychology) and their teachers was investigated using the questionnaire method. Students’ pReferences practically do not depend on specialities. For all students, subgroups of upcycling enthusiasts and sceptics are observed which regularly resort to upcycling or almost do not use it. An almost complete misunderstanding and imperception of the benefits and importance of upcycling is a key and common problem. Social factors have a minimal influence on the opinion of respondents, which may indicate a lack of understanding in society of the role and importance of waste management. All the shortcomings and problems in understanding upcycling are common to students and teachers. In general, the positive attitude towards upcycling and the intention to use upcycling in life in the answers most likely has an unconscious and artificial character (like a fashion trend) because the attitude towards other formative factors does not support it. The identified problems are related to the shortcomings of secondary school and undergraduate curricula, which hinder the formation of the necessary competencies for sustainable development. Methods of their solution are proposed and discussed.

FIP Brisbane 2023: Industrial Pharmacy

Accepted abstracts under the theme: Industrial Pharmacy (n=13)

Modern approaches to the introduction of higher education degrees for the speciality 226 Pharmacy, industrial pharmacy

The main direction of the development of the education system in Ukraine is the introduction of European standards, technologies, norms, and perspectives to ensure competitiveness in the market of European education services.
 The study aimed to highlight modern approaches to the standardization of higher education in the context of shaping professional competences of future pharmacists, to identify peculiarities and possibilities of applying a systemic approach to the development of a higher education standard for the specialty of 226 Pharmacy, Industrial Pharmacy of the second (master’s) level.
 The research materials consisted of references containing information on the development, approval, and implementation of higher education standard. The following methods were used in the study: synthetic, analytical, information search, descriptive, and generalization.
 The pharmaceutical industry is socially significant, and the specialty of 226 Pharmacy, Industrial Pharmacy, as well as all the specialties in the field of study 22 Health, are regulated. Therefore, professionals in this field should possess integrated knowledge and skills, be able to solve complex tasks and problems in the field of pharmacy and healthcare, both in practice and during the learning process. This involves conducting research, implementing innovations, and is characterized by uncertain conditions and requirements. A modern approach also involves the use of highly efficient technologies in the national and international educational and scientific environments, which ensure the preparation of competitive, highly qualified pharmaceutical professionals with moral and spiritual values, social responsibility, and community orientation. They are capable of providing quality pharmaceutical care to people and possess «soft skills».
 Upon the development of the approved higher education standard for the specialty of 226 Pharmacy, Industrial Pharmacy by the Ministry of Education and Science of Ukraine, the educational and professional programs Pharmacy and Perfume and Cosmetic Technologies were revised, and a list of competences as well as program learning outcomes for future pharmaceutical professionals was specified. These were aligned with the demands of the labor market and a professional-oriented approach, based on the concept of competences for a modern pharmacist and the variable components of educational and professional training programs

Pharmacoinformatics: the latest IT technologies in the educational process, scientific and practical pharmacy

It has been established that the developed information systems and databases make it possible to create a single information space that will unite drug manufacturers, intermediaries, pharmacies and consumers, government structures, pharmaceutical enterprises and pharmaceutical companies. Such a unified information space will create an opportunity to conduct various researches in real time. It has been proven that the study of the course "Pharmacoinformatics" in higher education institutions of Ukraine for students of specialty 226 "Pharmacy, industrial pharmacy" of two specializations 226.01 "Pharmacy" and 226.02 "Industrial pharmacy" is a fundamental process on the way to the realization of future specialists in the pharmaceutical industry.

NASAL ADMINISTRATION OF SILVER NANOPARTICLES AND SILVER IONS REDUCED COGNITIVE PERFORMANCE IN ADULT RATS

Background: Silver nanoparticles (AgNPs) have shown adverse effects and a toxic impact on human cell bodies. Passing the blood-brain barrier and increasing oxidative stress can change different parts of the brain such as the hippocampus. Therefore, the purpose of this investigation was to explore the possible neurotoxicity of AgNPs in adult rats. Method: Neurotoxicity was created in rats by treating them with 15 mg/kg NP3 and silver ions (AgAc) intra-nasally every two days for 20 days. The animals were divided into five groups: control, vehicle, NP3, NP15, and AgAc. Behavioral assessments such as Morris water maze and elevated plus maze, and assessment of biomarkers such as malondialdehyde assay were used to evaluate cognitive impairment and molecular changes induced by silver. Result: The results revealed that NP15 and AgAc significantly impaired spatial memory. Moreover, NP3, NP15, and AgAc increased anxiety in animals. Additionally, MDA was significantly increased by NP3 and NP15. Conclusion: The findings showed that AgNPs and AgAc, particularly NP15, result in neurotoxicity and behavioral impairments. Peer Review History: Received: 26 February 2023; Revised: 13 March; Accepted: 28 April 2023, Available online: 15 May 2023 Academic Editor: Dr. Nuray Arı, Ankara University, Turkiye, ari@ankara.edu.tr Received file: Reviewer's Comments: Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewers: Dr. Sally A. El-Zahaby, Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Salman International University, Egypt, sally.elzahaby@yahoo.com Dr. Robert Tungadi, State University of Gorontalo, Indonesia, rtungadi@yahoo.com

State of health of medical students

This article discusses the state of health of young students studying Pharmacy, Industrial Pharmacy at the Volyn Medical University. The purpose of the article is to determine the state of health of students of higher education in the medical profession. The results of the analysis of students' medical records allow us to state the presence of problems in their state of health. Each student of higher education during the academic year, on average, was ill 2–3 times and missed 10–15 days of study at the institute (depending on age and gender).
 Most often, students are sick with viral respiratory diseases (43-51 cases per 100 examined), diseases of the digestive organs (10-18 cases), vision (3-15 cases) and excretory system (5-12 cases), injuries (10-20 cases ) and infectious diseases (7– 14 cases).
 One of the integral criteria of adaptation is the assessment of the state of health on the basis of morbidity indicators, the level of which allows to most objectively reflect the degree of health loss, as well as to determine the priorities of prevention. Given the fact that the environmental factor has priority in the development of diseases in young people (up to 30%), the dominance of the specified pathologies may indicate the formation of an environmental maladaptation syndrome. Along with that, today the range of factors of the internal student environment has significantly expanded, which determine up to 12.5% of cases of illness in junior courses.
 According to the results of our research, the largest group in the structure of students' diseases is acute respiratory viral diseases. Influenza among students of higher education, of various ages, is registered in one-third to one-half of cases.
 In connection with the deterioration of students' health, it is necessary to introduce special, health-improving classes into the educational process, which would allow providing individual assistance to students in the prevention of diseases and health preservation.

Optimization, Fabrication and Characterization of Novel Meloxicam-Loaded Surface Attached Solid Dispersions to Ameliorate its Aqueous Solubility and Dissolution Employing Spray-Drying Technique

Objective: To formulate unmodified crystalline meloxicam solid dispersions by the use of surfactants and polymer. This polymeric particulate system is named as meloxicam-loaded surface attached solid dispersion (MSDs). Methodology: This experimental study was conducted at Lab of Physical and Industrial Pharmacy, Hanyang University, South Korea. The duration of this study was around seven months. The first phase of this study (optimization and fabrication) was completed within 3 months, while, solubility, dissolution and physicochemical characterization was completed in next 4 months. These surfaces attached solid dispersions were prepared by using spray drying technology. Moreover, HPMC and SLS were used as hydrophilic carriers. Various MSDs were prepared using carriers/drug, and were evaluated for aqueous solubility and dissolution studies. Results: Amongst different formulation prepared, MSDs3 having Meloxicam/HPMC/SLS in a (1:0.5:0.5) gave the highest solubility and dissolution (i.e. from 0.25 ±0.17ug/ml of meloxicam to 153 ±5.3ug/ml). Moreover, dissolution was enhanced from 2.96 ±0.55% to 47 ±1.07% at 15 minutes. Furthermore, physicochemical characterization was performed by scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and powder X-ray diffraction (PXRD). Conclusion: In conclusion we can predict a better solubility and dissolution of meloxicam in surface attached solid dispersion. Keywords: Meloxicam, solubility enhancement, spray drying, surface attached, solid dispersion

Quality Analysis of Various National and International Brands of Glimepirides Available in Pakistan

Objective: The primary focus of this research is to ascertain that these different generic drug products from national and multinational companies competing in the local market are equivalent in quality. Material and Methods: A comparative quality analysis was executed on national and multinational brands of glimepiride tablets obtained from local pharmacies of Hyderabad. A cumulative of 6 glimepiride brands were selected and internationally accepted in-vitro tests were carried out at Industrial pharmacy laboratory of Department of Pharmaceutics, Faculty of Pharmacy, University of Sindh, Jamshoro, during time period August 2021 to August 2022 to compare with Pharmacopoeia standards. Results: All the drug products (Glimepiride tablets) obtained from local market were meeting the standards laid by BP for tests of weight uniformity, diameter, thickness, hardness, friability, disintegration, and content uniformity/assay. Conclusion: Every generic of glimepiride tablets from various local and multinational manufacturers are pharmaceutical equivalents and can be prescribed interchangeably. Keywords: National, International, Brand, Glimepiride, Quality, Pharmaceutical Equivalents

A questionnaire based survey among pharmacy practitioners to evaluate the level of knowledge and confidence towards antimicrobial stewardship.

Our study aimed to assess the knowledge, understanding and confidence of the practicing pharmacists in UAE as an antimicrobial Stewards. Antimicrobial resistance threatens the achievements of modern medicine globally, and it's highly required for the AMS principles to be implemented in our communities. A cross-sectional online- questionnaire based survey was used among UAE pharmacy practitioners from different areas of practice who are holding pharmaceutical degrees and/or licensed pharmacists. The questionnaire was sent to the participants via social media platforms. The questionnaire was validated, and reliability assessment was made prior to the conduct. A total of 117 pharmacists responded to this study, out of which (70.9%, n=83) were females. Pharmacists which are from various practice fields participated in the survey, but the majority were pharmacists in Hospital pharmacies or Clinical pharmacists (47%, n=55), also community pharmacists (35.9%, n=42), while only (16.9%, n=20) ware from other areas of pharmacy including industrial pharmacy and academia. The majority of participants 88.9% (n= 104) were interested in pursuing their career as an Infectious disease pharmacist or getting a certificate in antimicrobial stewardship. The mean scores in the knowledge towards antimicrobial resistance was 3.75 (poor: 1-1.6, moderate: 1.7-3.3. 3.4-5), indicates that the pharmacists have a good level of knowledge towards AMR. A total of 84.3% of participants succeeded in Identifying the correct intervention for antibiotic resistance. The findings also showed that the total mean score of hospital pharmacists (mean=10.6±1.12), and the average of the scores of community pharmacists (mean=9.8±1.38), were non-significant between the different area of practice. 52.3% of the participants had a training on antimicrobial stewardship during their experiential rotation which reflected on their confidence in their performance and knowledge assessment (p value < 0.05). The study concluded good knowledge and high confidence levels among practicing pharmacists in UAE. However, the findings also identify areas of improvement in the practicing pharmacist, and the significant relationship between the knowledge and confidence scores reflects the ability of the practicing pharmacists to integrate the AMS principles within the UAE, which aligns with the attainability of the improvement.

METHODS OF ORGANIZING AND CONDUCTING LABORATORY WORK IN TEACHING PHARMACEUTICAL CHEMISTRY FOR STUDENTS MAJORING IN «PHARMACY, INDUSTRIAL PHARMACY»

Therelevanceofthescientifictopicisbasedonfindingandsolvingtheproblemsofselectingandimproving themethodologyoforganizationandconductinglaboratoryworkintheteachingofpharmaceuticalchemistryfor students of the «Pharmacy, industrial pharmacy» specialty. The purpose of the article is to study the peculiaritiesoftheprocessofteachingthediscipline«PharmaceuticalChemistry»forstudentsofthe«Pharmacy,industrial pharmacy»specialty.Themethodologicalapproachoftheresearchisbasedonthemethodsofanalysis,synthesis, comparison,andgeneralization.Intheprocessofconductinga surveyoffull-timestudents,problemsduringthe study of pharmaceutical chemistry were identified and ways to improve the methodology of teaching laboratory work were outlined. A methodological toolkit was developed to improve the level of teaching pharmaceutical chemistry forpharmacy students, namely: the use of multimedia interactive lectures; development of electronic courses; method ofrole-playing games; preparation and defence of term papers; application of lectures or laboratory-practical classes with consideration of various professional situations, with proposed false formulas, definitions, possible mechanismsofreactions.Intheprocessofconductingtheformativestageoftheexperiment,theuseofa virtualeducational environment and multimedia lectures took place. Prospective directions for improving the methodology of organizingand conducting laboratory work in teaching pharmaceutical chemistry for students majoring in «Pharmacy, industrial pharmacy» have been formed. The practical value of the work lies in the improvement of organizational methods and conducting laboratory work on a specific topic

РОЗВИТОК НАВИЧОК САМОДОПОМОГИ У КОНТЕКСТІ ПРАКТИЧНОЇ ПІДГОТОВКИ МАГІСТРІВ ФАРМАЦІЇ З ПИТАНЬ ПСИХІЧНОГО ЗДОРОВ'Я

Background. The aftermath of the war in Ukraine highlights the harmful effects of stressful situations on both the local population and pharmaceutical professionals. Undertaking preventative measures to maintain the mental well-being of the population, while also establishing selfhelp mechanisms in the workplace for issues related to mental health, will improve the quality of pharmaceutical care in the field of drug sales and curb early professional burnout among pharmacists. The purpose of this study is to perform a comparative analysis of educational and professional programmes in the specialty of 226 Pharmacy, Industrial Pharmacy, with the objective of assessing the level of masters of pharmacy training in facilitating their own mental health. The study will further investigate the incorporation of relevant course components in the curriculum. Methods. To attain the research goal, the authors utilized scientific literature, worldwide documents, official websites of academic Hiher education institutions, educational and professional programmes within the specialty of 226 Pharmacy, Industrial Pharmacy employing comparative analysis, systematisation, and generalisation methods. Results. The article presents a comparative analysis of educational and professional courses for Masters of Pharmacy in the 226 Pharmacy, Industrial Pharmacy Speciality. The documents and research findings of international scholars have been systematised to tackle the training of pharmacists to handle stressful situations and emergencies. Conclusions. The research conducted indicates that self-help in the workplace of pharmacists is a prevalent global practice, and it has been incorporated into specialised mental health education programmes in various countries. The authors believe that incorporating the best educational practices from Masters of Pharmacy training to include self help for mental health issues in the workplace into national educational and professional programmes in the 226 Pharmacy, Industrial Pharmacy specialty shows promise.

PHYSICAL HEALTH OF STUDENTS AND DIGITALIZATION OF HIGHER MEDICAL EDUCATION: RISK FACTORS.

The aim: To study the dynamics of gadget use by higher education students of the Bogomolets National Medical University and to assess technological impact on the physical health of students. Materials and methods: To accomplish the tasks set using theoretical and experimental methods of scientific research: systematic analysis, comparison and generalization of the bibliosemantic method, questionnaires, and interviews with students. Quantitative data collected during the survey of students studying in the «Dentistry», «Pediatrics», «Medicine», «Pharmacy, Industrial Pharmacy», «Physical Therapy, Occupational Therapy», and «Medical Psychology» specialties were processed using the MedCalc statistical software, and there was carried out comparative analysis afterwards. Results: During the quarantine and martial law, medical university students were forced to study distantly or in a mixed format using various gadgets and computers. It is obvious that the physical condition of a person is affected by the duration of their use of various devices. In this paper, therefore, the risks and the researched dynamics of gadget use by higher education students of the Bogomolets National Medical University were identified. Thus, the technological impact on the physical health of students was also defined. Moreover, the data based on the results of height and weigh calculation of higher education students, which used to diagnose types of obesity by anthropometric indicators, were also collected. Conclusions: According to the results of the research, it was established that the students of the Bogomolets National Medical University spent a significant part of their study time sitting in the classroom or at the computer (40 hours weekly average). We found that in the process of distance learning, prolonged sitting at a PC or other gadget (as well as general sedentary lifestyle) has affected the female higher education students majoring in 222 «Medicine» course their body mass index. The time spent using gadgets both in the educational and non-formal education (self-education) processes has increased significantly. We attribute this fact to the emergence of a significant number of online educational resources in the public domain, the growing number of webinars, trainings, and master classes conducted by both domestic and foreign experts online.