This study aims to analyze the influence of macroeconomic variables and world oil prices in influencing stock price movements on the Indonesian Sharia Stock Index (ISSI) in 2018-2022. In this case, stock price movements can be influenced by several factors, one of which is macroeconomics. The research methodology used in this study is to use a quantitative research approach and secondary data type, with quarterly samples from each year 2018 to 2022 which amounted to. The research model carried out is log linear regression panel data analysis conducted through the chow test and classical assumptions using Eviews 10 tools. Based on the results of this study, it states that partially shows the variables of Inflation, BI Interest Rate Economic Growth (GDP) and Money Supply. While simultaneously all variables did not have a significant effect on the Indonesian Sharia Stock Index (ISSI).