Individual Trajectories Of Change Research Articles

Investigating the developmental timing of self-regulation in early childhood

Self-regulation often refers to the executive influence of cognitive resources to alter prepotent responses. The ability to engage cognitive resources as a form of executive process emerges and improves in the preschool-age years while the dominance of prepotent responses, such as emotional reactions, begins to decline from toddlerhood onward. However, little direct empirical evidence addresses the timing of an age-related increase in executive processes and a decrease in age-related prepotent responses over the course of early childhood. To address this gap, we examined children’s individual trajectories of change in prepotent responses and executive processes over time. At four age points (24 months, 36 months, 48 months, and 5 years), we observed children (46% female) during a procedure in which mothers were busy with work and told their children they had to wait to open a gift. Prepotent responses included children’s interest in and desire for the gift and their anger about the wait. Executive processes included children’s use of focused distraction, which is the strategy considered optimal for self-regulation in a waiting task. We examined individual differences in the timing of age-related changes in the proportion of time spent expressing a prepotent response and engaging executive processes using a series of nonlinear (generalized logistic) growth models. As hypothesized, the average proportion of time children expressed prepotent responses decreased with age, and the average proportion of time engaged in executive processes increased with age. Individual differences in the developmental timing of changes in prepotent responses and executive process were correlated r = .35 such that the timing of decrease in proportion of time expressing prepotent responses was coupled with the timing of increase in proportion of time engaging executive processes.

Individual variations in 'brain age' relate to early-life factors more than to longitudinal brain change.

Brain age is a widely used index for quantifying individuals' brain health as deviation from a normative brain aging trajectory. Higher-than-expected brain age is thought partially to reflect above-average rate of brain aging. Here, we explicitly tested this assumption in two independent large test datasets (UK Biobank [main] and Lifebrain [replication]; longitudinal observations ≈ 2750 and 4200) by assessing the relationship between cross-sectional and longitudinal estimates of brain age. Brain age models were estimated in two different training datasets (n ≈ 38,000 [main] and 1800 individuals [replication]) based on brain structural features. The results showed no association between cross-sectional brain age and the rate of brain change measured longitudinally. Rather, brain age in adulthood was associated with the congenital factors of birth weight and polygenic scores of brain age, assumed to reflect a constant, lifelong influence on brain structure from early life. The results call for nuanced interpretations of cross-sectional indices of the aging brain and question their validity as markers of ongoing within-person changes of the aging brain. Longitudinal imaging data should be preferred whenever the goal is to understand individual change trajectories of brain and cognition in aging.

Upper Limb Performance in Daily Life Approaches Plateau Around Three to Six Weeks Post-stroke

Background. Wearable sensors allow for direct measurement of upper limb (UL) performance in daily life. Objective. To map the trajectory of UL performance and its relationships to other factors post-stroke. Methods. Participants (n = 67) with first stroke and UL paresis were assessed at 2, 4, 6, 8, 12, 16, 20, and 24 weeks after stroke. Assessments captured UL impairment (Fugl-Meyer), capacity for activity (Action Research Arm Test), and performance of activity in daily life (accelerometer variables of use ratio and hours of paretic limb activity), along with other potential modifying factors. We modeled individual trajectories of change for each measurement level and the moderating effects on UL performance trajectories. Results. Individual trajectories were best fit with a 3-parameter logistic model, capturing the rapid growth early after stroke within the longer data collection period. Plateaus (90% of asymptote) in impairment (bootstrap mean ± SE: 32 ± 4 days post-stroke) preceded those in capacity (41 ± 4 days). Plateau in performance, as measured by the use ratio (24 ± 5 days), tended to precede plateaus in impairment and capacity. Plateau in performance, as measured by hours of paretic activity (41 ± 6 days), occurred at a similar time to that of capacity and slightly lagged impairment. Modifiers of performance trajectories were capacity, concordance, UL rehabilitation, depressive symptomatology, and cognition. Conclusions. Upper limb performance in daily life approached plateau 3 to 6 weeks post-stroke. Individuals with stroke started to achieve a stable pattern of UL use in daily life early, often before neurological impairments and functional capacity started to stabilize.

중학생의 창의인성 개인별 변화궤적 분류에 대한 교수 활동 피드백의 효과

중학생의 창의인성 개인별 변화궤적 분류에 대한 교수 활동 피드백의 효과

Trajectories of Changes in Renal Function in Patients with Acute Heart Failure

BackgroundChanges in renal function have been associated with differential outcomes in patients with acute heart failure (HF). However, individual trajectories of changes in renal function are unknown, and it is unclear whether they relate to different clinical characteristics and clinical outcomes. Our aim was to investigate the prognostic importance of individual trajectories of change in renal function in acute HF. MethodsThis was a retrospective, observational analysis from the double-blind, randomized, placebo-controlled PROTECT trial in patients with acute HF. We identified and internally validated 8 different renal trajectories among 1897 patients by visual inspection of inhospital serum creatinine changes. The primary outcome measure was all-cause mortality at 180 days. Mean age was 70 ± 12 years; 70% were male, and mean baseline estimated glomerular filtration rate was 49.0 mL/min/1.73m2. ResultsA total of 8 different trajectories was established. The most prevalent trajectories were an inhospital bump (19.0%), a sustained increase (17.6%) and a dip (14.5%) in serum creatinine. Overall, the clinical characteristics of patients in different trajectories were remarkably similar. Crude 180-day mortality rates ranged from 12.0% in the trajectory, with no significant changes to 18.3% in the trajectory of sustained increase without significant differences. Overall, after multivariable adjustment, there was no trajectory of changes in renal function that was associated with significantly better or worse outcomes. ConclusionsTrajectories of changes in renal function in acute HF differ considerably on the patient level. Despite these differences, clinical characteristics and outcomes were similar, therefore, questioning the prognostic importance of changes in renal function in acute HF.

Varieties of Religious and Pornographic Experience: Latent Growth in Adolescents’ Religiosity and Pornography Use

ABSTRACTThe relationship between adolescent religiosity and pornography use has been longitudinally tested only in the United States. Given the social relevance of hypothesized mechanisms underlying the association, this study offers a three-wave longitudinal assessment of parallel latent growth in the two constructs carried out in a Southern European country. Using responses of 1,041 Croatian adolescents from the capital city (Mage = 16.14 years, SD = .45; 64.6% of female students) and latent growth curve modeling approach, we explored links between individual trajectories of change in religiosity and pornography use over a period of 24 months. In the observed period, religiosity decreased and pornography use increased among both male and female adolescents, but their dynamics were independent of each other—pointing to other (unmeasured) processes responsible for both adolescents’ sexualization and secularization. Important to note, the findings also pointed to an important role of age at first exposure to pornography for its frequency of use in middle to late adolescence.

Trajectories of change in symptom distress in a clinical group of late adolescents: The role of maladaptive personality traits and relations with parents.

In this study, it was analysed whether trajectories of change in symptom distress could be identified in a clinical group of late adolescents with personality pathology. Furthermore, it was examined whether maladaptive personality traits and relations with parents were predictive of following one of these trajectories. Three latent classes emerged from growth mixture modelling with a symptom inventory (n = 911): a Stable High, a Strong Decreasing and a Moderate Decreasing trajectory. Subsequently, by using multinomial logistic regression analyses in a subsample of late‐adolescents (n = 127), it was revealed that high levels of Negative Affectivity and Detachment were predictive of following the Strong Decreasing, and high levels of Detachment were predictive of following the Stable High trajectory. Support from or Negative Interactions with parents were not predictive of any of the trajectories. The current results contribute to the notion of individual trajectories of change in symptom distress and provide suggestions for screening patients on personality traits to gain insight in the course of this change. © 2018 The Authors Personality and Mental Health Published by John Wiley & Sons Ltd

ACT-enhanced behavior therapy in group format for Trichotillomania: An effectiveness study

BackgroundThis study sought to investigate the effectiveness of group treatment for trichotillomania (TTM) in ordinary clinical settings. Treatment consisted of a combination of habit reversal training (HRT) and acceptance and commitment treatment (ACT). Both short- and long-term effects were explored, as well as individual change trajectories. MethodsThe sample consist of fifty-three patients with TTM. Treatment outcomes were evaluated at post-treatment and at one-year follow-up using self-report questionnaires (Massachusetts General Hospital Hair Pulling Scale, MGH-HS), structured clinical interviews (National Institute of Mental Health Trichotillomania Severity Scale, NIMH-TSS), and the Clinical Global Impression scale for TTM (CGI-TTM). ResultsAnalyses by mixed models for repeated measurements yielded a statistically significant effect of time (p<.001) for all outcome measures. There were large effect sizes, ranging from 1.76 to 2.33 at post-treatment and from 1.03 to 1.43 at one-year follow-up. Nearly 90% of patients scored below the diagnostic threshold at post-treatment on the CGI-TTM, and slightly more than 60% remained so at one-year follow-up. There were large and statistically significant differences in the change profiles across the patients from post-treatment to one year follow-up. ConclusionsACT-enhanced behavior therapy in a group format seems efficient for reducing symptoms of trichotillomania.

Differential responses of positive affect, negative affect, and worry in CBT for generalized anxiety disorder: A person-specific analysis of symptom course during therapy

Introduction: Research indicates that individuals with generalized anxiety disorder (GAD) may experience deficits in positive affect (PA), and tend to dampen or intentionally suppress PA. Despite the presence of PA-related pathology in GAD, little is known about change in PA during GAD treatment. Objective: This study examines changes in PA, negative affect (NA) and worry in seven participants during cognitive behavioral therapy (CBT) for GAD. Method: Intensive repeated measures (i.e., time series) data were subjected to person-specific regression analysis to delineate individual change trajectories. Results: Significant improvement in worry was observed in all but one participant. Fear and irritability - indices of NA - each improved in 5/7 participants while sadness improved in 4/7 participants (worsening in one). Of all symptom domains, PA had the poorest treatment response: PA improved in only 2/7 participants and actually significantly worsened in 5/7 individuals even as NA and worry improved during therapy. Conclusion: These findings indicate that treatment gains from traditional CBT for GAD may not generalize to improvements in PA regulation, or even emotional functioning more broadly. This evidence is a call to increase the focus on PA regulation in treatment for GAD; perhaps PA could be a missing piece in our understanding of ways to bolster GAD treatment outcomes.

The impact of student teaching experience on pre-service teachers’ readiness for technology integration: A mixed methods study with growth curve modeling

Adopting a two-phase explanatory sequential mixed methods research design, the current study examined the impact of student teaching experiences on pre-service teachers’ readiness for technology integration. In phase-1 of quantitative investigation, 2-level growth curve models were fitted using online repeated measures survey data collected from 68 pre-service teachers doing their student teaching. The results revealed significant progress in readiness for technology integration during student teaching and significant variability in individual change trajectories of readiness for technology integration. Two dummy variables, prior-teaching (0 = “having no prior teaching experience”; 1 = “having prior teaching experience”) and grade-level (0 = “elementary level”; 1 = “secondary level”), were identified as significant in predicting the shape of individual change trajectories of readiness for technology integration. In phase-2 of qualitative investigation, follow-up interview data were collected from 11 pre-service teachers among those who participated in the online surveys. The interview data was analyzed both deductively and inductively yielding clues and insights for interpreting and understanding the quantitative results from phase-1. Based on its quantitative and qualitative results, this study made recommendations for future technology integration research and for improving pre-service teachers’ technology use experience during student teaching.

Advances in the Evaluation of Longitudinal Construct Validity of Clinical Outcome Assessments.

Historically, the assessment of longitudinal construct validity in the field of psychosocial measurement involved defining hypotheses and calculating correlation coefficients using scores based on 2 measures at 2 or more time points. In the context of patient-reported outcomes, this evolved into sensitivity to change and responsiveness, including the computation of effect size estimates of change, standardized response means, and indices such as Guyatt's statistic. Cross-sectional analyses or analyses based on 2 time points have been the standard practice. Evolving conceptualizations have incorporated more than 2 time points and have included depictions of individual trajectories of change in multiple measures, structural equation models, and mixed modeling techniques. The focus of this article is on methods to evaluate longitudinal construct validity. We describe a sample of these methods and provide considerations and recommendations for designing a thoughtful longitudinal construct validity evaluation of clinical outcome assessments.

Atypical working memory decline across the adult lifespan in autism spectrum disorder?

Whereas working memory (WM) performance in typical development increases across childhood and adolescence, and decreases during adulthood, WM development seems to be delayed in young individuals with autism spectrum disorder (ASD). How WM changes when individuals with ASD grow old is largely unknown. We bridge this gap with a cross-sectional study comparing age-related patterns in WM performance (n-back task: 3 load levels) among a large sample of individuals with and without ASD (N = 275) over the entire adult life span (19-79 years) as well as interindividual differences therein. Results demonstrated that, despite longer RTs, adults with ASD showed similar WM performance to adults without ASD. Age-related differences appeared to be different among adults with and without ASD as adults without ASD showed an age-related decline in WM performance, which was not so evident in adults with ASD. Moreover, only IQ scores reliably dissociated interindividual differences in age-gradients, but no evidence was found for a role of basic demographics, comorbidities, and executive functions. These findings provide initial insights into how ASD modulates cognitive aging, but also underline the need for further WM research into late adulthood in ASD and for analyzing individual change trajectories in longitudinal studies.

Differential changes in functional disability and pain intensity over the course of psychological treatment for children with chronic pain

Patients presenting for treatment of chronic pain often believe that pain reduction must be achieved before returning to normal functioning. However, treatment programs for chronic pain typically take a rehabilitative approach, emphasizing decreasing pain-related disability first with the expectation that pain reduction will follow. This information is routinely provided to patients, yet no studies have systematically examined the actual trajectories of pain and disability in a clinical care setting. In this study of youth with chronic pain (N=94, 8 to 18 years), it was hypothesized that 1) functional disability and pain would decrease over the course of psychological treatment for chronic pain and 2) functional disability would decrease more quickly than pain intensity. Participants received cognitive behavioral therapy (CBT) for pain management (M=5.6 sessions) plus standard medical care. The Functional Disability Inventory and a Numeric Rating Scale of average pain intensity were completed by the child at every CBT session. Hierarchical linear modeling was conducted to examine the longitudinal trajectories of disability and pain. Standardized estimates of the slopes of change were obtained to test differences in rates of change between pain and disability. Results showed an overall significant decline in functional disability over time. Although pain scores reduced slightly from pretreatment to posttreatment, the longitudinal decline over treatment was not statistically significant. As expected, the rate of change of disability was significantly more rapid than pain. Evidence for variability in treatment response was noted, suggesting the need for additional research into individual trajectories of change in pediatric pain treatment.

Modeling Change in the Presence of Nonrandomly Missing Data: Evaluating a Shared Parameter Mixture Model

In longitudinal research, interest often centers on individual trajectories of change over time. When there is missing data, a concern is whether data are systematically missing as a function of the individual trajectories. Such a missing data process, termed random coefficient-dependent missingness, is statistically nonignorable and can bias parameter estimates obtained from conventional growth models that assume missing data are missing at random. This article describes a shared parameter mixture model (SPMM) for testing the sensitivity of growth model parameter estimates to a random coefficient-dependent missingness mechanism. Simulations show that the SPMM recovers trajectory estimates as well as or better than a standard growth model across a range of missing data conditions. The article concludes with practical advice for longitudinal data analysts.

Mapping the individual-level dynamics of perceived discrimination and attitudes toward multiculturalism and cultural maintenance: A pre-post study of migration

This three-wave study among ethnic migrants from Russia to Finland (N=136) investigated the stability and change of attitudes toward cultural diversity, i.e., support for multiculturalism and preference for cultural maintenance, over the course of migration. More specifically, we expected changes in these attitudes to be a result of changes in perceived ethnic discrimination. We were also able to look at the empirical relationship of these conceptually linked attitudes over time. A latent change modeling approach was employed to examine individual change trajectories in discrimination and the two attitudes of interest, while controlling for expectations related to them in the pre-migration stage. The results indicated that, on average, the variables of interest were rather positive over time. With regard to the observed changes, individual changes in support for multiculturalism were associated with changes in cultural maintenance in the post-migration stage, but changes in perceived discrimination were not associated with changes in these two attitudes. Thus, the results of the present longitudinal study speak for the robustness of attitudes toward cultural diversity in the face of adversity.

Change Patterns of Homeless Individuals with Mental Illness: A Multiple Case Study

This multiple case study illuminates the individual change trajectories of four homeless men with mental illnesses who participated in a manualized life skills intervention to improve housing retention. Readiness-to-change, life skills knowledge and trauma symptoms were measured at baseline, post-intervention and at 3-6 months follow-up. Cluster analysis identified two patterns of readiness-to-change: engaged and pre-engaged. Change is non-linear and baseline readiness is not necessary to benefit from the intervention. Examining individuals' lives in context illuminated the change process and demonstrated that varied patterns can lead to successful outcomes for housing stability and community reintegration.

Maternal Intrusiveness, Family Financial Means, and Anxiety Across Childhood in a Large Multiphase Sample of Community Youth

Intrusive parenting has been positively associated with child anxiety, although examinations of this relationship to date have been largely confined to middle to upper middle class families and have rarely used longitudinal designs. With several leading interventions for child anxiety emphasizing the reduction of parental intrusiveness, it is critical to determine whether the links between parental intrusiveness and child anxiety broadly apply to families of all financial means, and whether parental intrusiveness prospectively predicts the development of child anxiety. This study employed latent growth curve analysis to evaluate the interactive effects of maternal intrusiveness and financial means on the developmental trajectory of child anxiety from 1st grade to age 15 in 1,121 children (50.7% male) and their parents from the NICHD SECCYD. The overall model was found to provide good fit, revealing that early maternal intrusiveness and financial means did not impact individual trajectories of change in child anxiety, which were stable from 1st to 5th grade, and then decrease from 5th grade to age 15. Cross-sectional analyses also examined whether family financial means moderated contemporaneous relationships between maternal intrusiveness and child anxiety in 3rd and 5th grades. The relationship between maternal intrusiveness and child anxiety was moderated by family financial means for 1st graders, with stronger links found among children of lower family financial means, but not for 3rd and 5th graders. Neither maternal intrusiveness nor financial means in 1st grade predicted subsequent changes in anxiety across childhood. Findings help elucidate for whom and when maternal intrusiveness has the greatest link with child anxiety and can inform targeted treatment efforts.

Using Individual Growth Curve Models to Predict Recovery and Activities of Daily Living After Spinal Cord Injury: An SCIRehab Project Study

ObjectiveTo evaluate change in functional outcomes over 1 year after spinal cord injury (SCI). DesignObservational longitudinal secondary analysis. SettingSix rehabilitation facilities participating in the SCIRehab project. ParticipantsPatients (N=1146) with SCI enrolled from 2007 to 2010. InterventionsNot applicable. Main Outcome MeasuresFIM instrument 13-item and 11-item motor, 3-item transfer, 6-item self-care, 3-item self-care upper-extremity, and 3-item self-care lower-extremity subscores modeled as trajectories of change. ResultsPatients were on average 37 years old, non-Hispanic white, with high school or higher education, a body mass index of 25, and a Comprehensive Severity Index score of 20. Most were men with paraplegia (37%) or high tetraplegia (27%). Median time frames were 22 days from injury to admission, 46 days from admission to discharge, 407 days from admission to follow-up, and 44 days for rehabilitation length of stay. The motor subscores were higher on admission for paraplegia and American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade D groups, and recovered faster for the AIS grade D group. Lower function at admission was associated with older age, higher Comprehensive Severity Index score, longer length of stay, fewer physical therapy and therapeutic recreation hours, and more occupational therapy hours. Slower recovery rates were associated with older age, more days from injury to admission, and fewer physical therapy hours per week. ConclusionsLongitudinal outcomes modeled as individual trajectories of change are clinically meaningful. Individual growth curve models could facilitate recovery prediction and outcome evaluation at individual and group levels. However, assessment of the effects of treatment on outcome trajectories will require the addition of outcome measures at time points during intervention and may require the use of outcome measures specific to aspects of rehabilitation, such as mobility and self-care.

Working memory ability predicts trajectories of early alcohol use in adolescents: the mediational role of impulsivity

(i) To evaluate the role of pre-existing weakness in working memory ability (WM) as a risk factor for early alcohol use as mediated by different forms of impulsivity and (ii) to assess the adverse effects of progressive alcohol use on variations in WM over time. A community sample of 358 adolescents [48% males, mean(age) (baseline) = 11.4 ± 0.87 years] from a longitudinal cohort design, assessed annually over 4 consecutive years with less than 6% attrition. Repeated assessments were conducted for the following key variables: WM (based on performance on four separate tasks), frequency of alcohol use (AU) and three forms of impulsivity, namely sensation seeking (SS), acting without thinking (AWT) and delay discounting (DD). Latent growth curve modeling procedures were used to identify individual trajectories of change for all key variables. Weakness in WM (at baseline) predicted significantly both concurrent alcohol use and increased frequency of use over the four waves (P < 0.05). This effect was entirely mediated by two forms of impulsivity, AWT and DD, both of which were characterized by underlying weakness in WM. No individual variation was observed in the slopes of WM, which suggests that individual variations in alcohol use were not associated with changes in WM in our early adolescent sample. Early adolescent alcohol use may be a consequence of (pre-existing) weaknesses in working memory (WM) rather than a cause of it. Efforts to reduce early alcohol use should consider the distinct roles of different impulsivity dimensions, in addition to WM, as potential targets of intervention.

A Preliminary Assessment of the Local Diversity of Family Farms Change Trajectories Since 1950 in a Pyrenees Mountains Area

In agriculture and environmental sustainability research, assessment of local diversity of individual farm dynamics and farmers' behaviors appears of special interest for enlightening changes in ecological, social, and economical functions related to farming in rural communities and landscapes. It also includes challenges due to current methodology limitations. In this study, we developed a method for assessing the variety in individual change trajectories since 1950 of farms in a case study area in the Pyrenees (France). Changes in individual farms and households over the period were described at a five-year step using a set of indicators selected in reference to a social-ecological model of family farm dynamics. They were respectively categorized using a spatial-temporal multivariate analysis method. Results gained on a 24-farm sample showed four contrasted farm-development trajectories that could be related to lifecycle patterns of individual households. This opens new prospects for integrated assessment of individual farms' dynamics within a local agricultural system.