Group Of Individuals Research Articles

Cranial Fluctuating Asymmetry and Schizophrenia in a contemporary Danish population

Post-mortem Computed Tomography (PMCT) scans in forensic medicine not only assists with case work but is also a useful data source for other imaging-based research, e.g. morphological studies on bones. PMCT 3D data can be combined with diagnostic information and help to elucidate how disease manifests in the body. For example, the skeleton can be influenced by developmental instability, which may result in a morphological change called fluctuating asymmetry (FA). Developmental instability also influences the risk of developing schizophrenia, which means that individuals with higher levels of developmental instability, and by extension FA, might have a higher risk of developing the disorder. This connection has been investigated in soft tissues but has not yet been investigated in bones. We used PMCT 3D models from a forensic cohort to compare levels of cranial FA between a group of individuals with diagnosed schizophrenia and a control group. Our sample included 48 individuals with diagnosed schizophrenia and 58 controls. We collected 27 landmarks from our 3D models. Levels of fluctuating asymmetry were analyzed using Procrustes ANOVA, and the two groups were compared using t-test and Wilcoxon rank sum test. Age and sex were tested as factors using Pearson correlation and two-way ANOVA. We found that there was no statistically significant difference in levels of cranial FA between the schizophrenic group and the control group, and that neither age nor sex was a factor. Our results confirm earlier studies that suggest that the multifactorial aetiology of FA and schizophrenia is difficult to capture comprehensively.

Research Review: Why do prospective and retrospective measures of maltreatment differ? A narrative review.

Childhood maltreatment contributes to a large mental health burden worldwide. Different measures of childhood maltreatment are not equivalent and may capture meaningful differences. In particular, prospective and retrospective measures of maltreatment identify different groups of individuals and are differentially associated with psychopathology. However, the reasons behind these discrepancies have not yet been comprehensively mapped. In this review, we draw on multi-disciplinary research and present an integrated framework to explain maltreatment measurement disagreement. We identified three interrelated domains. First, methodological issues related to measurement and data collection methods. Second, the role of memory in influencing retrospective reports of maltreatment. Finally, the motivations individuals may have to disclose, withhold, or fabricate information about maltreatment. A greater understanding of maltreatment measurement disagreement may point to new ways to conceptualise and assess maltreatment. Furthermore, it may help uncover mechanisms underlying maltreatment-related psychopathology and targets for novel interventions.

Using word cloud as a formative assessment classroom technique in physiology.

Formative assessment is a valuable tool in medical education as it allows students to reflect on their own learning and make necessary corrections. The use of innovative techniques in formative assessment can make it more engaging and effective for students, particularly utilizing electronic tools. A word cloud is a visual representation of data that is created using text inputs from a group of individuals. The resulting image shows the most frequently used words in a larger font, allowing quick understanding of the common themes and concepts in the group's responses. Mentimeter is an online platform for interactive presentations where students can provide their responses to a question, which can then be visualized as a word cloud. The study aims to explore the benefits and drawbacks of using word cloud formation as a formative assessment technique in the classroom, utilizing the online platform Mentimeter.NEW & NOTEWORTHY The current study was conducted to present a novel formative assessment classroom technique using Mentimeter. The benefit of this novel technique is that it is easy to implement, quick, anonymous, and strengthens student's conceptual learning. It also gives the teacher an opportunity to give feedback and stress commonly committed mistakes.

Effects of relative humidity on atmospheric organosulfur species derived from photooxidation and nocturnal chemistry in a forest environment

The molecular composition of organic aerosols in ambient PM2.5 was investigated at the northern foothills of Qinling Mountain region in central China during the summer of 2022. The molecular characteristics of organic matter were analyzed using ultrahigh performance liquid chromatography coupled with high-resolution Orbitrap mass spectrometry. The number of molecular formula assignments was dominated by organosulfur species (OrgS, on average 28–47% in total). Both the number and peak area of OrgS increased significantly with higher relative humidity (RH), while those of CHO and CHON species decreased, indicating the different impacts of RH on individual organic groups. The entire study period was divided into two distinct stages, including a low RH and a high RH period (LRH and HRH). The enhanced formation of CHOS with O>7 in HRH was primarily attributed to photochemical oxidation, whereas the increase in CHONS with O>7 was driven by enhanced NO3 radical-initiated oxidation under elevated RH conditions. Nearly 50% of OrgS presented only in HRH had aliphatic structures with C≥9. Although isoprene-derived organosulfates dominated the peak area across the entire period, the monoterpenes and long-chain alkanes-derived organosulfates largely increased in HRH. The strong correlations between aerosol liquid water content and OrgS containing high oxygen content (O>7) indicate that aqueous-phase reactions played a crucial role in multigenerational oxidation of OrgS. This study highlights the important effects of RH on the formation of OrgS, particularly for organosulfates derived from monoterpenes and long-chain alkanes.

Patterns of HIV treatment preferences among people with diverse demographic, social, and behavioral characteristics who are living with HIV in the United States.

New dosage form and frequency options may improve HIV treatment outcomes and reduce disparities in access and use. People with HIV (PWH) in the US completed a demographic and discrete choice experiment survey of preference for 13 hypothetical HIV treatment options: daily and weekly oral tablets; 1-, 3-, or 6-monthly injections by self or a health care provider; yearly implant; or combinations. Best-worst scaling and a latent class model were used to analyze overall preference choices and for groups of individuals with similar patterns of preferences; the model also predicted uptake of products. Among the diverse 829 respondents, weekly oral tablets and 6-monthly injections by an HCP were significantly more favored than daily oral tablets. Convenience of the treatment and being tired of taking pills were the top drivers of preference responses. Latent class analysis identified four groups of respondents with distinct preference patterns; approximately two-thirds belonged to groups strongly preferring products other than daily oral tablets. The modelled uptake of a monthly pill, yearly implant, 6-monthly Health Care Provider (HCP) injection, oral daily pill, and 3-monthly HCP injection were 24%, 24%, 24%, 18%, and 11%, respectively. Patterns of HIV medication preference can inform development of new forms of HIV therapy products as the majority of patients do not prefer the currently most available treatment option of daily oral tablets. Looking beyond population-level preferences and into similar groups of PWH increases the ability to develop patient-centered products to fill gaps in care and increase treatment effectiveness.

The applications of Ursodeoxycholic acid in infant with cholestasis: A retrospective cohort analysis

Biliary atresia is the predominant etiology of cholestasis in early infancy. Impairment of bile fluid excretion results in elevated bilirubin levels, causing a yellowing of the skin. Ursodeoxycholic acid is well-established to enhance liver function when taken promptly. The application of ursodeoxycholic acid for treating cholestasis in pediatric patients remains contentious. The objective of this study is to assess the impact of ursodeoxycholic acid treatment on liver biomarkers in infant with cholestasis. This was retrospective cohort study in infant with cholestasis who underwent ursodeoxycholic acid treatment for two weeks. Secondary data including aspartate aminotransferase, alanine aminotransferase, total bilirubin, and direct bilirubin were extracted from the medical records of the outpatient clinic in the Department of Child Health at Dr. Soetomo General Hospital, Indonesia (January 2020 - December 2023). The data was devided into two groups based on biopsy and examined utilizing SPSS version 23. This study included 64 participants. Statistics show an equal gender ratio. Ursodeoxycholic acid treatment in paediatric cholestasis patients can lower liver biomarker level. Levels of total bilirubin and direct bilirubin diminished in individuals both groups. Notable levels were recorded in individuals with normal biopsy outcomes (p=0.007 and p=0.012). Administration of ursodeoxycholic acid markedly elevated ALT levels in both the normal and abnormal liver biopsy outcome groups (p=0.031 and p=0.006). Ursodeoxycholic acid has been shown to be effective in improving liver function in infant with cholestasis. In order to avoid negative effects, the medication must be carefully administered to people who already have liver fibrosis.

How to improve sustainability of nutrient dense diets for children and adolescents: an exemplary assessment in Germany.

The global climate crisis requires a paradigm shift in dietary concepts, respecting the needs of children. A global reference diet has been suggested by the EAT-Lancet Commission. On this basis, the detailed "Planetary Health Diet Index" (PHDI) has been proposed. The objective of this assessment is (1) to apply the PHDI to the Food-Based Dietary Guidelines, the so-called Optimized Mixed Diet (OMD) for children and adolescents in Germany in its original composition and (2) to check how the planetary value of the OMD could be improved by modifying food selection within meals while keeping the high nutrient densities of the guideline diet. The PHDI specifies 16 food groups and their proportion of total daily energy intake. The PHDI of the original OMD was calculated by assigning the foods of the 7-day menu to the PHDI food groups in order to score them. In this way, it became apparent which food groups had the potential to improve the sustainability. The diet was then updated by either reducing or increasing individual foods from these food groups in the meals and deriving the resulting PHDI. The nutrient densities of the original and updated daily OMD were calculated. The original diet obtained a PHDI score of 68.24 points, representing 45.5% of the theoretical maximum of 150 points. The following food groups achieved 9.9 to 10 out of 10 points: fruits, total vegetables, fish&seafood, vegetable oils, chicken (and substitutes). Conversely, food groups receiving a zero score included tubers&potatoes, dairy, red meat, animal fat, and added sugars. The updated diet resulted in increased consumption of 'nuts&peanuts', 'legumes', 'green vegetables', 'whole grains', and decreased consumption of 'tubers&potatoes' and 'red meat'. Overall, the PHDI increased from 68.24 to 81.51 points with the updated OMD, reflecting a 13.27% increase compared to the original diet. The nutrient densities were not significantly affected, but even slightly increased for most nutrients. The PHDI was applied to demonstrate how the sustainability of the guideline diet for children and adolescents in Germany could be improved through changes in individual food groups that can be easily implemented in practice while maintaining high nutrient densities and acceptability for children. NA.

“Roses, Bruises, Wholeness” Development and Implementation of a Psychological Healing Program on Depression of Women Victims of Intimate Partner Violence

The study aimed to develop and implement an intervention program for the psychological healing of depression of women victims of intimate partner violence. To lay the groundwork and come up with the data needed to develop an intervention program, the study used the Sequential Explanatory Design. This mixed method suggests gathering and evaluating the quantitative data and qualitative data in two consecutive phases. The data-gathering tools used in the study included the Beck Depression Inventory (BDI-II) to measure the depression level of the participants; a Semi-structured interview and a focus group discussion were conducted to provide the data needed for the qualitative phase. A pretest of the BDI-II was administered to the participants. Results showed that the participants were found to have depression during the time of the administration of the test. The BDI’s results provided the formation of the experimental and the control groups while the individual interview and focus group discussion provided the themes used in the development of the intervention program. These themes were categorized based on Physical Violence, Psychological Violence, Sexual Violence, and Neglect according to the Diagnostic Manual for Mental Disorders 5 (DSM5-TR). The experimental group participated in the eight-session intervention program and the control group did not participate in the sessions. Subsequently, a posttest was administered to the experimental and the control groups. Results showed that the six experimental group participants decreased their depression level significantly, except for one participant who got a four-point increase in her posttest score. There was no significant difference in the pretest and post-test scores of the control group.

The Influence of Facial Injury during the First World War on the Development of Plastic and Reconstructive Surgery in Britain and Germany.

In the First World War (WW1), different types of injuries became both political and economic factors for the main belligerent countries. This work illustrates the special role facial injuries played during and after the war and the profound impact they had on the field of Plastic Surgery in Britain and Germany.This is a historical work based on primary and secondary sources. English and German material was used to compile an overview of the development of Plastic and Reconstructive Surgery as a specialty during WW1 and up to the Second World War (WW2).Plastic and Reconstructive Surgery had the task of reconstructing male beauty and personalities, restoring the most intense, disfigured reminders of a terrible war in homes and the public. Looking at the significant role the specialty played during the war, remarkably, most of the contributors struggled to find financial support to develop designated specialized departments in the inter-war period. The specialty's connection to the emotional subject of facial disfigurement did not work in its favor at a time when people wanted to forget the horrors of the war.The developments in Britain and Germany during the WW1 were less isolated than often described and the inter-war period saw much effort for international collaboration. The different developments of WW2 further illustrate how essential the efforts of a strong group of individuals and support from authorities were for the evolution of Plastic Surgery as a specialty.

Faktor-faktor Yyng Mempengaruhi Rendahnya Motivasi Belajar Siswa

The low motivation to learn varies depending on the goals to be achieved in the learning process at school. The level of motivation can be seen from the attitude of students during teaching and learning activities. Motivation to learn can arise or change influenced by various factors. According to Dimyati & Mudjiono (2002) factors that influence learning motivation include students' ideals or aspirations, individual abilities, personal conditions, student environment, dynamic elements in the learning process, and teacher efforts in teaching. This study aims to describe: 1) Factors that influence students' low motivation to learn in terms of factors: a. students' ideals or aspirations, b. students' abilities, c. students' conditions, d. students' environmental conditions, e. dynamic elements in learning and teaching, f. teachers' efforts in teaching students. The method used in this study is quantitative with a descriptive research type. The research sample was 69 students of SMK Pariwisata Aisyiyah Padang in grades X, XI, and XII who were registered in the 2024/2025 academic year who were selected based on the Total Sampling technique. Data were obtained by distributing research instruments in the form of questionnaires on factors that influence low student learning motivation that have been tested for validity and reliability. Data were processed using the Percentage Technique. The results of this study indicate that: 1) factors that influence low student learning motivation are reviewed from the following factors: a. Student ideals or aspirations: difficulty in determining interests and talents (56.62%), b. Student abilities: difficulty focusing on processing lesson materials (47.83%), c. Student conditions: difficulty attending school due to health problems (44.93%), d. Student environmental conditions: avoid talking to deskmates (39.13%), d. Dynamic elements in learning and teaching: easily distracted by things around them that hinder the ability to focus on lesson materials (46.38%), e. Teacher efforts in teaching students: teachers do not provide good examples in learning discipline (44.93%). The implications of guidance and counseling services that can be provided are information services, individual counseling services and group counseling services.

The state of cancer care in Russia: malignant tumors of the skin (C44). One- and five-years survival of patients, age characteristics. Part II.

In the first part of our study, we presented an analysis of the prevalence, quality of primary registration, annual mortality, and the peculiarities of changes in the localization and histological structure of malignant neoplasms (C44) of the skin. In the second part of our research, special attention will be focused on assessing the effectiveness of anti-cancer measures concerning observed and relative one-year and cumulative five-year survival rates in the Northwestern Federal District of Russia (NWFD). The database created in 2019 for the population cancer register (PCR) at the federal district level has significantly expanded the possibilities for conducting analytical research, including the potential to study rare tumors. In this work, we will pay special attention to the new opportunity to conduct an in-depth analysis of the dynamics of localization and histological structure. We will examine the survival of patients with skin neoplasms from any affected area (lips, ears, face, back, extremities, and other parts), which is not feasible when evaluating prevalence based on state reporting forms, not to mention calculating patient survival rates. The aim of this research is to study the patterns of one-year and five-year survival of patients with skin neoplasms (C44) taking into account the main parameters of the registration card. The conducted research revealed a positive trend in the one-year observed survival of patients with skin neoplasms (C44) in the Northwestern Federal District of the Russian Federation, which increased from 95.6% to 96.2% between 2000 and 2019, with higher rates for the female population at 96.3% and 96.9%, respectively. The specificity of the level and dynamics of individual age groups of patients was identified. For the first time, the one-year survival of patients with skin neoplasms was calculated based on detailed tumor localizations and the respective one-year survival rates, as well as the one-year survival calculated separately for each tumor histotype. The highest survival rate was observed for the histotype M-8090/3 at 97.4%, while the lowest was for M-8390/3 at 59.1%.

Characterizing Research Teams

Abstract Research in health professions education (HPE) is often executed by teams—groups of individuals working together to solve a problem, reconceptualize an issue, or conduct a study. Teams frequently involve individuals from different disciplinary backgrounds or professions1,2 who work collaboratively to accomplish specific scholarly goals. Matching team composition to research goals is critical for ensuring the team has the skills and perspectives necessary to generate, integrate, and mobilize the desired knowledge. Drawing on literature,3,4 we describe the who, what, how, and when of 4 types of research teams.

The European Rare Kidney Disease Reference Network

Rare kidney diseases encompass awide range of congenital, inherited and acquired conditions. Two million Europeans are affected by rare kidney diseases. The European Rare Kidney Disease Reference Network (ERKNet) aims to improve the clinical management of patients with these diseases. ERKNet encompasses 95highly specialized adult and pediatric nephrology units at 72sites in 24European Union (EU) member states, as well as agroup of patient advocates (European Patient Advocacy Group, ePAG). ERKNet centers care for more than 65,000 rare kidney disease patients and pursues avariety of activities. An online consultation service helps improve the management of complex cases. Expert working groups develop clinical practice guidelines for individual groups of rare kidney diseases. In a3-year postgraduate program, junior physicians at ERKNet centers are trained by experts in the diagnosis and treatment of rare kidney diseases through webinars and case-based eLearning modules. Information brochures and online texts on rare kidney diseases for patients, relatives and the general public are produced and disseminated. Clinical research is supported by aEuropean Registry for Rare Kidney Diseases (ERKReg), which provides important information on demographics and disease progression and facilitates the identification of patient cohorts for therapeutic studies. In addition, the registry provides clinical performance statistics of reference centers and allows benchmarking to promote the harmonization and standardization of care for rare kidney disease patients across Europe.

The Processuality of ‘Sex’ in Biomedicine: Exploring Stem Cell Research, Cancer Medicine and Vaccine Safety Research

Incorporating sex into biomedical research is envisioned as key to addressing inequalities in health. However, feminist research suggests that it is a complicated task. This is, we argue, especially the case with research that seeks to mobilise sex across different scales involving bodies, samples and populations to provide a basis for personalised biomedical prevention and treatment. Through case studies from stem cell research, cancer medicine and vaccine safety research, we analyse how sex is enacted, foregrounded and sidelined at different stages of research. We argue that sex becomes suspended between individual bodies, samples and population groups, and that this postpones biomedical analysis of sex differences in health. Yet, research on sex differences in complex embodied processes, such as drug metabolism or immunity, appears as a future potentiality. This potentiality shapes research practices that may open biomedicine towards multi-disciplinary study settings that bring together physiological and social dimensions of bodily difference.

Life After EBPs: Characterizing Subsequent Engagement in Evidence-Based Psychotherapy After Completion of an Initial Trauma-Focused EBP in a National Sample of VA Patients.

Many Veterans who complete prolonged exposure (PE) or cognitive processing therapy (CPT) report residual symptoms, but it is unclear how to best address the mental health needs of these individuals. Examining patterns of mental health service utilization following completion of these two treatments may provide insight into how to best serve this group of individuals. In a large cohort of Veterans (N = 12,514) who sought treatment in the Veterans Health Administration during Fiscal Years 2015-2019, logistic regression models were used to assess the odds of initiating an additional course of trauma-focused (i.e., PE or CPT) or depression-focused psychotherapy in the year following completion of PE or CPT based on demographic, psychiatric, and treatment effectiveness-related variables. Approximately 9% of Veterans engaged in either trauma-(6%) or depression-(3%) related psychotherapy in the year following discharge from PE or CPT. Factors associated with increased odds of trauma-focused treatment initiation included having a sleep disorder diagnosis (OR = 1.23), a substance use disorder diagnosis (OR = 1.27), or experiencing military sexual trauma (OR = 1.64). Factors associated with increased odds of depression-focused treatment initiation included having a depression diagnosis (OR = 2.02). This study suggests that certain subgroups of Veterans who engage in PE or CPT (e.g., Veterans with comorbid sleep or substance use problems) are more likely to seek additional evidence-based treatment and may require augmentations to maximize clinical benefits, either during the initial course of treatment or subsequent to PTSD treatment.

Shared orbitofrontal dynamics to a drug-themed movie track craving and recovery in heroin addiction.

Movies captivate groups of individuals (the audience), especially if they contain themes of common motivational interest to the group. In drug addiction, a key mechanism is maladaptive motivational salience attribution whereby drug cues outcompete other reinforcers within the same environment or context. We predicted that while watching a drug-themed movie, where cues for drugs and other stimuli share a continuous narrative context, fMRI responses in individuals with heroin use disorder (iHUD) will preferentially synchronize during drug scenes. Thirty inpatient iHUD (24 male) and 25 healthy controls (16 male) watched a drug-themed movie at baseline and at follow-up after 15 weeks. Results revealed such drug-biased synchronization in the orbitofrontal cortex (OFC), ventromedial and ventrolateral prefrontal cortex, and insula. After 15 weeks during ongoing inpatient treatment, there was a significant reduction in this drug-biased shared response in the OFC, which correlated with a concomitant reduction in dynamically-measured craving, suggesting synchronized OFC responses to a drug-themed movie as a neural marker of craving and recovery in iHUD.

Factors associated with self-initiated moves during the formal eviction process

Abstract Housing eviction is a common occurrence, affecting hundreds of thousands of Europeans annually. It is well known that it primarily impacts the most vulnerable groups in society and is associated with adverse outcomes. However, previous research heavily relies on enforced removals registered in official statistics, thus missing eviction outcomes that do not undergo or disrupt the formal eviction process. This exploratory study, based on unique national Swedish register data on evictions with a sample of over 60,000 individuals, examines self-initiated moves and contrasts them with enforced removals and lease regain. Results from univariable and multivariable multinomial logistic regression analyses indicate that economic hardship and living in a single household are associated with both self-initiated moves and enforced removals. However, distinct factors associated with self-initiated moves are aged under twenty-five, living as a couple with children, residing in a non-metropolitan municipality, and having a native background. Gender-stratified analysis highlights strong associations for young women and native-background women with self-initiated moves. The results underscore the significance of implementing preventive social services interventions that address the specific needs of this larger group of individuals who face evictions under a broader definition. Further implications for research, policy, and social work practice are discussed.

Latent characterisation of the complete BATSE gamma ray bursts catalogue using Gaussian mixture of factor analysers and model-estimated overlap-based syncytial clustering

Abstract Characterising and distinguishing gamma-ray bursts (GRBs) has interested astronomers for many decades. While some authors have found two or three groups of GRBs by analyzing only a few parameters, recent work identified five ellipsoidally-shaped groups upon considering nine parameters T50, T90, F1, F2, F3, F4, P64, P256, P1024. Yet others suggest sub-classes within the two or three groups found earlier. Using a mixture model of Gaussian factor analysers, we analysed 1150 GRBs, that had nine parameters observed, from the current Burst and Transient Source Experiment (BATSE) catalogue, and again established five ellipsoidal-shaped groups to describe the GRBs. These five groups are characterised in terms of their average duration, fluence and spectrum as shorter-faint-hard, long-intermediate-soft, long-intermediate-intermediate, long-bright-intermediate and short-faint-hard. The use of factor analysers in describing individual group densities allows for a more thorough group-wise characterisation of the parameters in terms of a few latent features. However, given the discrepancy with many other existing studies that advocated for two or three groups, we also performed model-estimated overlap-based syncytial clustering (MOBSynC) that successively merges poorer-separated groups. The five ellipsoidal groups merge into three and then into two groups, one with GRBs of low durations and the other having longer duration GRBs. These groups are also characterised in terms of a few latent factors made up of the nine parameters. Our analysis provides context for all three sets of results, and in doing so, details a multi-layered characterisation of the BATSE GRBs, while also explaining the structure in their variability.

Trends in Exercise-Related Internet Search Keywords by Sex, Age, and Lifestyle: Infodemiological Study.

Exercise prescription by physicians is beneficial for initiating or intensifying physical activity. However, providing specific exercise prescriptions is challenging; therefore, few physicians prescribe exercise. This infodemiological study aimed to understand trends in exercise-related internet search keywords based on sex, age, and environmental factors to help doctors prescribe exercise more easily. Search keyword volume was collected from Yahoo! JAPAN for 2022. Ten exercise-related terms were analyzed to assess exercise interest. Total search activities were analyzed by sex and age. Characteristic scores were based on the Japanese prefecture. By performing hierarchical cluster analysis, regional features were examined, and Kruskal-Wallis tests were used to assess relationships with population and industry data. The top-searched term was "Pilates" (266,000 queries). Male individuals showed higher interest in activities such as "running" (25,400/40,700, 62.4%), "muscle training" (65,800/111,000, 59.3%), and "hiking" (23,400/40,400, 57.9%) than female individuals. Female individuals exhibited higher interest in "Pilates" (199,000/266,000, 74.8%), "yoga" (86,200/117,000, 73.7%), and "tai chi" (45,300/65,900, 68.7%) than male individuals. Based on age, search activity was highest in the 40-49 years age group for both male and female individuals across most terms. For male individuals, 7 of the 10 searched terms' volume peaked for those in their 40s; "stretch" was most popular among those in their 50s; and "tai chi" and "radio calisthenics" had the highest search volume for those in their 70s. Female individuals in their 40s led the search volume for 9 of the 10 terms, with the exception of "tai chi," which peaked for those in their 70s. Hierarchical cluster analysis using a characteristic score as a variable classified prefectures into 4 clusters. The characteristics of these clusters were as follows: cluster 1 had the largest population and a thriving tertiary industry, and individuals tended to search for Pilates and yoga. Following cluster 1, cluster 2, with its substantial population, had a thriving secondary industry, with searches for radio calisthenics and exercise bike. Cluster 4 had a small population, a thriving primary industry, and the lowest search volume for any term. Cluster 3 had a similar population to that of cluster 4 but had a larger secondary industry. Male individuals show more interest in individual activities, such as running, whereas female individuals are interested in group activities, such as Pilates. Despite the high search volume among individuals in their 40s, actual exercise habits are low among those in their 30s to 50s. Search volumes for instructor-led exercises are higher in cluster 1 than in other cluster areas, and the total number of searches decreases as the community size decreases. These results suggest that trends in search behavior depending on sex, age, and environment factors are essential when prescribing exercise for effective behavioral change.

Perceptions des gestantes sur le vaccin contre la COVID-19 à Kinshasa, R.D. Congo. Etude qualitative multicentrique menée dans la Zone de santé de Binza Ozone

The aim of this study was to understand pregnant women's perceptions of vaccination against COVID-19. The study was conducted using a qualitative approach. Data was collected through individual interviews and focus groups. Data analysis consisted of a thematic analysis of the content of the interviews. The target population was made up of pregnant women who had attended the maternity units selected for the study in the Binza Ozone Health Zone. The main results showed that pregnant women's willingness to be vaccinated was hampered by fear and concern about serious adverse post-vaccinal events, congenital malformations in the unborn baby, premature deliveries and low birth weight babies. Vaccinating pregnant women against COVID-19 is one of the effective strategies that can be put in place to protect them from the fatal complications of COVID-19.