Native Research Articles

Exploring Demographic Representation and Reporting in Lung Cancer Clinical Trials with Canadian Sites from 2013 to 2023

This review evaluates the reporting of demographic characteristics and the diversity of participants of phase III lung cancer clinical trials with Canadian research sites. A literature search was conducted using the ClinicalTrials.gov registry to identify clinical trials conducted between 1 January 2013, and 31 December 2023. The demographic reporting practices and the representation of sex/gender, racial, and ethnic groups were assessed. The location of Canadian research sites was also examined for trends in reporting and representation. Associated publications were reviewed for demographic data collection methods. Of the 25 clinical trials, 24 reported race and 18 also reported ethnicity. All clinical trials reported sex/gender, and the city and province of the participating Canadian sites. Most participants were White (66.1%), identified as not Hispanic or Latino (81.4%), and were male (57.8%). The provinces with the most clinical trial sites were Ontario (43.6%) and Quebec (34.2%). Lung cancer clinical trials lack adequate demographic reporting and representation of females, diverse patient groups, and geographical locations in Canada with high lung cancer incidence rates. Specifically, the Indigenous Peoples of Canada and Nunavut require better representation in lung cancer clinical trials conducted in Canada. These findings highlight the need to improve diversity and demographic representation in clinical research.

Indigenous dance, sport-for-development, and settler colonial (de)choreographies in the Indian Residential School System

ABSTRACT The Department of Indian Affairs and church counterparts who administered Canada’s Indian Residential School System promoted Euro-Canadian physical activities to reform and replace traditional Indigenous physical culture practices like the Sundance and the potlatch. Administrators used Western forms of movement to compel obedience to Euro-Canadian culture, including spirituality. An observer wrote that the students ‘must not sing, dance, beat a drum, or pray in the Indian way. They may dance in the manner of the White people …’ (Sheridan, ca. 1930s). The use of sport for such social engineering, usually by colonial state and church missions, has been called sport-for-development. This paper examines how these institutions conceptually framed, and put into practice, their interventions into Indigenous physical cultures using the terrain of the body. I argue that the Indian residential school system imposed ‘settler colonial choreographies’ in a domestic sport-for-development process.

Prevalence of Trehalase Enzymopathy Genetic Determinants in Siberian and Russian Far East Populations.

. Using the Infinium iSelect HD Custom BeadChip biochip (Illumina, United States) on the iScan platform and real-time polymerase chain reaction on a Bio-Rad CFX96 Touch amplifier, genotyping of 1068 DNA samples was carried out, of which 667 represent 10 ethnic groups of the indigenous people of the North of Siberia and the Far East of the Russian Federation. Two reference groups (357 samples) of Russians (n=311) and Yakuts (n = 46) represent the "Caucasoid" and "Mongoloid" poles of the Russian population. : The reduced trehalase activity that the heterozygous GA*TREH genotype determines can manifest itself in 19.8-53.7% of indigenous northerners. An additional 1.0 to 19.7% of the population are carriers of the AA*TREH genotype, which is associated with apparent trehalose malabsorption. The carriers may experience nausea, abdominal pain, and other dyspeptic symptoms after eating trehalose containing foods. The total risk of trehalase enzymopathy among the indigenous northerners in the Asian part of the Russian Federation is very high and can reach 60-70%. There is a gradient in the A*TREH allele frequencies in the small-numbered indigenous northern groups of Russia from the west (Khanty, Mansi, Nenets) to the east (peoples of the Far East). : The results are consistent with previously reported data on the higher carriage of the A*TREH mutant allele in Mongoloid populations compared to Caucasoid groups. It was hypothesized that, while the initial A*TREH allele prevalence in Mongoloid groups was moderately high, an adaptation to a low-sugar protein-lipid "high-latitude" diet led to a weaker control over the maintenance of the carriage of the ancestral G* allele. Trehalose malabsorption requires special attention of specialists in the field of nutrition, gastroenterology, public health, and medical genetics working in high-latitude regions.

Lake-centred sedentary lifestyle of early Tibetan Plateau Indigenous populations at high elevation 4,400 years ago.

The onset of sedentism on the Tibetan Plateau is often presumed to be associated with the dispersal of agriculture or farmers from archaeological sites located in the low elevation margins of the plateau. Previous studies of the plateau assumed that all foragers were probably mobile, but few systematic excavations at forager sites have been conducted to inform us about their settlement patterns. Here we report the world's highest elevation sedentary way of living exhibited by the Mabu Co site at 4,446 metres above sea level, deep in the interior of the Tibetan Plateau 4,400-4,000 years ago. Our interdisciplinary study indicates that the site was occupied by Indigenous inhabitants of the plateau, representing the earliest known DNA evidence of foragers who predominantly harbour the southern plateau ancestry. The evidence shows that they had a sedentary lifestyle primarily supported by fishing at nearby lakes, supplemented by mammal and bird hunting, as well as small-scale exchanges of millet and rice crops.

The Need for Decolonized Education: A Textual Analysis of Existing Literature in the Public Domain in Support of the Canadian National Inquiry Documents Calls for Education

The significance of this study sits in the importance of restorying for decolonial education. The textual analysis of literature in public domain in support of the Canadian national inquiry documents (2015, Truth and Reconciliation Calls (TRC) and the Murdered and Missing Indigenous Women and Girls (MMIWG) Calls, 2019) highlighted the magnitude of story to curriculum and Indigenous culture. Barriers included contemporary issues in mainstream schooling. The prominence of culture within the interconnected relationship with land-based learning in curriculum development and programming for wellness/well-being on Turtle Island (North America) are paramount. The present-day state of affairs in the mainstream educational Canadian landscape is not aligned with Indigenous appropriate methodologies and culture as a subjective measure and therefore falls short. Cultural, societal and land-linked factors must be considered as indicators.

A summary framework for effective engagement of IPLCs and rangers

In this paper we focus on the pressing need to effectively engage with Indigenous Peoples and Local Communities (IPLCs) and the need to strengthen the capacity of rangers originating from these communities. Opportunities for full participation and leadership by IPLCs are improved by enhancing the role of Indigenous and local rangers in fostering relationships while integrating cultural knowledge into the work on the ground. This also strengthens local benefits. We emphasize the invaluable contribution of IPLCs to conservation, often honed over generations, and explore current models of partnership and engagement. Particularly, we spotlight the vital role of IPLC rangers, who leverage unique skills, local knowledge, and cultural practices in their conservation work. The roles of both IPLCs and local Indigenous rangers are essential if we are to meet our goals for conserving 30% of the earth’s lands and waters by 2030 as promoted at the COP15 meeting of the Convention on Biological Diversity (CBD), achieve the objectives for development of IPLC rangers as stated of Chitwan Declaration of 2019 (CD), or meet the related targets set by the Universal Ranger Support Alliance (URSA). We advocate for a partnership model with IPLCs that applies the principles of Collective Impact to improve outcomes and secure enduring benefits at all levels. To aid stakeholders in conservation projects involving IPLCs (including governments, businesses, and non-governmental organizations), we propose a straightforward summary framework that outlines stages for the development of relationships and projects. It integrates the work of others, including foundation principles, management systems for partnerships, and good practices, and stresses the need for pre-project training, learning and other forms of preparation. Altogether, these principles and accompanying recommendations help lay the groundwork for effective intergenerational projects involving IPLCs with long-term benefits.

Threats to Indigenous Tribal Peoples in Brazil during the Reign of Jair Bolsonaro and Ways to Combat Them

Threats to Indigenous Tribal Peoples in Brazil during the Reign of Jair Bolsonaro and Ways to Combat Them

Conflict potential of Central Asian immigration (using the example of the Yaroslavl region)

The article is devoted to the problem of conflict potential arising as a result of immigration to Russia of the indigenous population of the Central Asian states. Most researchers of labor migration from Central Asian countries to Russia have so far studied the problems of adaptation of migrants and their integration into Russian society. In addition, xenophobia towards migrants by the indigenous population of the Russian Federation is a common research topic, while the radicalization of migrants themselves in Russia and their participation in extremist movements remain poorly studied. The proposed study focuses on the conflict potential created by both temporary, labor, and permanent, long-term migration of the indigenous population of Central Asian countries to Russia. The relevance of the study is related to the sharp aggravation of the problem of Central Asian migration in Russia. Signs of this aggravation appeared even during the COVID-19 epidemic in the form of a sharp increase in the number of conflicts involving migrants, and became especially acute after the terrorist attack in Crocus City Hall. The practical significance of studying the conflict-causing potential of Central Asian immigration is due to the need to timely identify the social risks associated with it and develop measures to neutralize them.

Caracterización sociocultural y económica de producción de ovinos en comunidades indígenas, Tungurahua - Ecuador

Sheep production in Ecuador is mostly for self-consumption in rural areas and especially in indigenous communities, although some marketing practices may eventually be implemented with products derived from sheep farming, such as milk and wool, which, in addition come into play in the processes of sustaining cultural traditions. Starting from this conviction, this article aims to describe the sociocultural and economic characteristics of sheep production in the indigenous communities of the province of Tungurahua, among which the communities stand out, within the study area: Quisapincha, Tomabela, Chibuleos and the Salasacas. The methodology that guides the research is qualitative, with a documentary and field design, since it is, on the one hand, exposing some sociocultural features of the study population, as well as specifying economic variables of sheep production in the region. . The theoretical review shows the importance of sheep farming as a source of income for a good number of people from the indigenous communities in the country, also representing a factor of preservation of the native cultures settled in regions such as the Tungurahua Province. Among the conclusions derived from empirical observation, it can be added that in the indigenous sectors of the province, there is evidence of a lack of knowledge of the basic health systems that must be implemented on their farms, which affects production and the economic strength of production.

Relational Ontology in the Mapuche Thinking: Possibilities for Indigenous Well-Being Amidst Colonial Settings

The imposition of a colonial mindset over indigenous peoples and their relational understanding of life is a common experience in the Global South. Forced displacement and subordination are also part of history in which cultural manners to preserve balance with the environment were severely altered. This article delves into the case of the Mapuche people, an indigenous group from Latin America that faces old and new expressions of colonialism. Because of structural discrimination, the health outcomes of the Mapuche people have been affected, including mental health. In this scenario, intercultural health experiences have been implemented to address the needs of the Mapuche population. Intercultural health policy emerges as an arena in which indigenous understanding of well-being is once again subjugated. From the author’s indigenous position, possibilities for well-being come through the negotiation of meanings and power that complicate indigenous life in colonial settings. Moreover, the subalternization of indigenous perspectives within scientific spaces is acknowledged as an obstacle to achieving horizontality in academic networks and to constructing meaningful interventions.

Transcriptomic Analysis of the Effects of Changes in Temperature and Flow Velocity on Reproductive Ability of Coreius guichenoti

ABSTRACTThe establishment of reservoirs, which alter water temperature and flow dynamics, significantly affects the indigenous fish population, yet the underlying molecular mechanisms remain unclear. To investigate effects of the changing water temperature and flow rate on fish ovaries, we subjected female Coreius guichenoti to the combination of different water temperatures (17°C, 20°C and 23°C denoted as L, N and H, respectively) and flow velocities (0 and 0.5 m/s denoted as S and V, respectively). After 30‐day experiment period, we identified 393, 545, 300 and 657 differentially expressed transcripts in HV versus NV, LV versus NV, HS versus NV and LS versus NV, respectively. The transcriptome results showed that both environmental factors could significantly influence oogenesis, with water temperature exerting a more pronounced effect than flow velocity. In particular, the higher temperature (HV and HS) led to a tendency towards masculinization and even infertility in females, which were consistent with the histopathology results. By contrast, the lower temperature (LV and LS) promoted the progression of desirable female attributes, where static water conditions (LS) had a greater effect compared with flowing water (LV). These findings were of great significance for the adaptive operation of reservoirs to create reasonable and precise ecological flows for managing fish reproduction.

Sulat Pasa: Its Implications to Local Divorce Practice among the Sama of Tawi-Tawi, Philippines

This study investigates Tawi-Tawi’s sulat pasa (traditional divorce paper), particularly as it relates to Sama divorcees, and if it provides a workable way to end their marriage. Through qualitative-descriptive research, it reviews the characteristics of local divorce documents, the processes involved in getting them, and their effects and implications on local divorce practice. With the institutionalization of the Code of Muslim Personal Laws of the Philippines, Muslim Filipinos should follow the divorce procedures laid in it. However, this legal hybridity is seen as inadequate because it looks insensitive to the long-standing customs and beliefs of the Muslims, jeopardizing their autonomy and self-instituting cultural traditions about divorce. Furthermore, because divorce conflicts and their resolution have been entirely integrated into the Philippine judicial system, the existing system does not provide speedy resolution to the satisfaction of the Muslim divorcee/s. Despite the implementation of the Muslim Code, the study found that Sama in Tawi-Tawi continued to present and bring their divorce cases to the traditional authority for enforcement. Given the Code’s lax implementation, local divorce cases outside Shari’ah court proceedings remain critical. The study proposes a measure through direct parliament action, such as adding a provision to the existing Bangsamoro Organic Law once the Muslim Code is upgraded, and, in the interim, this can be done through collaboration with the National Commission on Muslim Filipinos, Ministry of Indigenous Peoples Affairs, local religious and elective officials, and women’s organizations to institutionalize the traditional divorce paper as also legal, and binding taking into account issues of accessibility, affordability, practicability, and feasibility.

Decolonizing decolonization projects: neoliberalism, Indigenous services, and Indigenous strategic change in Taiwan and Canada

ABSTRACT This article argues that though decolonization is an ongoing struggle globally, neoliberalism blunts the impacts of state and institutional decolonization projects. Drawing on the literature and three examples, the article explores the unintended consequences of decolonizing efforts in human services and universities, specifically how they reinforce neoliberalism and perpetuate aspects of ongoing colonialism. The analysis shows that adherence to managerial metrics and logics erases important aspects of decolonization such as Indigenous self-determination, sovereignty, and cultural safety. The article identifies five elements that should be present if decolonization is to be advanced decisively and shows that in each example, neoliberalism is foregrounded rather than the sovereignty of Indigenous people. We conclude that the examples analysed are a form of neoliberal colonialism rather than colonialism’s undoing.

Challenges in Making Inclusive and Comprehensive Public Policy on Ethno-educational Processes

This article presents the results of intercultural processes stemming from challenges in making inclusive and comprehensive public policies on ethno-educational matters based on the current public policies in Latin American countries, particularly Colombia. This qualitative, ethnographic research examined the perceptions of Indigenous educators vis-à-vis (sustituir por: in face of) the contemporary public policies on aboriginal communities. In doing so, this study employed individual and focus-group interviews and drew on a descriptive, analytical design that also considered a systematic review of antecedents to such policies. The findings evidence that the realities of Indigenous classroom practices and approaches are distant from those of urban settings and the principles and norms established in Colombia’s legislation and other countries. Lastly, the study highlights the need for constructing public policies that benefit Indigenous communities in Latin America and Colombia.

Knowledge, attitudes, and practices towards COVID-19 prevention among indigenous population in Malaysia: A cross-sectional study

The COVID-19 pandemic has become a significant challenge to humanity, especially marginalized groups such as indigenous people. This study aimed to assess the knowledge, attitude, and practice towards COVID-19 prevention among the indigenous population in Lipis district, Pahang, Malaysia. A cross-sectional study was conducted among the indigenous population and the data were collected through face-to-face interviews using a validated questionnaire. The mean score of knowledge, attitude, and practice were 2.35 (SD 1.104), 32.84 (SD 4.756), and 9.64 (SD 3.227), respectively. In the bivariable analysis, the younger the age (p < 0.001), and the higher the education level (p = 0.001) of the participants, the higher the knowledge score on COVID-19. Meanwhile, the female participants (p = 0.043) and the higher the household income, the higher the attitude score of the participants (p = 0.006). Factors that contributed to a higher score of practice towards COVID-19 prevention were younger age (p = 0.013), female (p < 0.001), no religion (p = 0.026), unemployed (p < 0.001), and higher household income (p = 0.012). There was a positive correlation between knowledge score and practice score (p = 0.001) and a positive correlation between attitude score and practice score (p < 0.001), respectively. Multivariable regression analysis showed that the younger age (p < 0.001) was significantly associated with a higher knowledge score. Furthermore, female (p = 0.018), unemployed (p = 0.001), higher knowledge score (p < 0.001), and higher attitude score (p < 0.001) were significantly associated with a higher score of practice towards COVID-19 prevention among the participants, respectively. Indigenous people in Malaysia have a good knowledge, attitude, and practice towards COVID-19. However, strategic planning and programmes related to preventive practices against infectious disease outbreaks need to be conducted continuously to reduce the outbreaks in the future.

O USO DOS RITMOS E DANÇAS NA EDUCAÇÃO ESCOLAR

This text is an excerpt from the Master’s Dissertation that addresses THE TRIPLE BORDER OF BRAZIL, PERU AND COLOMBIA: CULTURAL DIVERSITY AS A TEACHING TOOL IN A 3RD YEAR CLASS OF PIO VEIGA STATE SCHOOL IN THE MUNICIPALITY OF ATALAIA DO NORTE. Brazil is a country made up of great cultural diversity made up of different peoples, Africans, Europeans and indigenous people, each with their own customs, values ​​and beliefs, a mixture of different cultures. Schools located on borders, for example, are schools considered to have a higher rate of cultural diversity, as they are influenced by neighboring cities/countries. It is worth highlighting that Brazil has intense borders with several South American countries. Among these intense borders, in this study we will highlight the Triple Border: Brazil, Peru and Colombia. Although the school is a favorable environment for working with cultural diversity, what has been seen in the school environment is the great difficulty teachers have in integrating these diversities into their pedagogical practices. In this way, the school must assume the role of intermediary, for the study and knowledge of existing cultures within the school environment, through meaningful pedagogical practices. Thus, this study aimed to analyze how the cultural diversity of the triple border can contribute to the student training process.

Hauora hinengaro o takatāpui: analysing the effectiveness of mental health policies in addressing the needs of Takatāpui in Aotearoa New Zealand

Many studies have documented the effect that colonisation has had on takatāpui, that is, Māori (the Indigenous peoples of New Zealand) with diverse gender identities, sex characteristics and sexualities. In this paper, we explore whether current Aotearoa New Zealand (hereafter Aotearoa) mental health policies meet the needs of takatāpui. We identified five mental health policy needs, informed by the literature. We then explored policy documents from government ministries, district health boards and non-government organisations to see the extent to which policy met these needs. Four themes were present in the literature analysed: an overall lack of acknowledgment of takatāpui and intersectionality; promising engagement with the needs of takatāpui by NGOs; symbolic commitment to Te Tiriti o Waitangi; and some limited engagement with Māori health models. The findings show promise in some areas but demonstrate a lack of engagement by policy to meet the needs of takatāpui.

Decolonizing the National Park: Unsettling public space through Indigenous urbanism

ABSTRACT Despite warnings of decline, public space continues to play a pivotal role for social movements and democracies. Yet, because liberal concepts of public space are rooted in settler colonialism, they avoid critical engagement with histories and contemporary expressions of Indigenous urban life. The occupation of Bogotá’s National Park by Indigenous communities presents an opportunity to reexamine the limits of public space. While government officials espoused conventional definitions about public space, Indigenous occupants described the National Park in entirely different terms. They relied on a praxis known as the minga for sustenance, communication, spatial organization, community building, and political mobilization. Drawing on Indigenous urbanism, this article frames the occupation of the National Park as a practice of decolonization, which challenges the historical legitimacy of stolen land and the supremacy of property. It considers the minga as a practice of Indigenization and an epistemologically distinct form of citymaking.

Mapping forest-based natural climate solutions

Natural climate solutions are critical actions of ecosystem stewardship to mitigate climate change. However, prioritizing locations and possible actions is challenging. We demonstrate a generalizable approach for identifying potential opportunities for natural climate solutions by creating a spatial hierarchy of land management restrictions. Global forest carbon stocks and flux models were then used to explore forest-based natural climate solutions in the high-carbon density coastal temperate rainforests of western North America. Our results show 13 million hectares are available for action, an area that holds 4,900 ± 640 megatonnes of carbon dioxide equivalent and represents 45% of regional and 0.5% of global aboveground forest carbon stocks. Based on historical trends, a 10% reduction in average annual forest carbon loss through improved forest management and conservation could reduce forest carbon emissions by 9.1 megatonnes of carbon dioxide equivalent per year, corresponding to 5.2% of the 2030 land-based climate commitments made by the United States and Canada. Large-scale implementation of natural climate solutions will require collaborative planning with forest-dependent communities, industry, governments, and Indigenous peoples.

Continuity or Disruption? Rethinking Engagement in Multi-Stakeholder Forums Through the Lens of Boundary Objects

Multi-stakeholder forums (MSFs) are crucial for managing complex decision-making; yet ways for evaluating engagement, especially for Indigenous peoples, remain ambiguous. This study examines the Honduran Mosquitia, where conflict over the illegal occupation of Indigenous lands led to the creation and eventual dissolution of an MSF. It questions whether the continuity of formal dialogue structures signifies genuine engagement or if disruption might better indicate it. The study applies the lens of boundary objects—concepts or devices that enable collaboration among actors with differing agendas—to assess engagement. In Mosquitia, territorial governance served as a boundary object, fostering the establishment of an MSF. Government, donor, and Indigenous stakeholders had their distinct interests in supporting territorial governance. Indigenous stakeholders exited the MSF when their aims for securing land tenure were unmet, turning to civil disobedience to assert territorial governance. The MSF’s dissolution prevented the co-optation of territorial governance by government and donors, remaining a contentious term that more accurately reflected the tensions among stakeholders. This case shows how engagement might paradoxically be reflected in the MSF’s disruption.