The agricultural frontier of the Brazilian Amazon, is undergoing significant changes in its land cover, primarily driven by the expansion of cattle ranching and cocoa cultivation. Through the analysis of Landsat 8 satellite images and the WorldCover 10m 2020 product, combined with climatic and socioeconomic data, this study investigated land use dynamics between 2015 and 2023, on the municipality of Brasil Novo. The results revealed a substantial reduction in forest cover, with the expansion of pasturelands as the main driver of deforestation. The temporal analysis of the Normalized Difference Vegetation Index (NDVI) indicated interannual variations in vegetation cover, associated with extreme weather events and anthropogenic pressure. Although the municipality still maintains 43.8% of forest cover, with the Arara Indigenous Land being a notable example, the pressure on natural resources demands the implementation of public policies and sustainable management practices to mitigate environmental impacts and ensure the conservation of Amazonian biodiversity. Keywords: Amazon, NDVI, remote sensing, climate change, livestock, land use.