Abstract Introduction For reconstruction of the esophagus in children colon interposition and reconstruction of the esophagus by stomach should are most often used. This work aims to compare the quality of life of patients in these groups to determine the optimal method for esophageal reconstruction in children. Material and methods. For 6 years 167 esophageal replacement was performed at the Filatov Children's Hospital. Of these, 57 children were evaluated for quality of life through a questionnaire, which was carried out when the child was re-admitted for follow-up examinations. All operations were performed by the same team of surgeons. We compiled the questions in the questionnaires specifically for this group of patients, which are shown in the table 1. The questionnaire for children under 14 years of age was completed by parents. Older children 14-year-olds filled out the questionnaire independently. The respondents were divided into 2 groups. Group 1 – 26 children who underwent reconstruction of the esophagus by stomach. The 2nd group included 29 children after colonic interpositions. In terms of gender, age and indications for surgery were comparable in both groups. Patients were interviewed from 6 months to 5 years after surgery. Results Tab. 1 Comparative analysis of results interviewed patients in two groups Despite the fact that esophageal reconstruction by stomach is easier to perform and it is even possible to perform this operation laparoscopically, as can be seen from the table above, children have significantly more problems in many indicators affecting the quality of life. Conclusions Reconstruction of the esophagus by stomach should be used for: reoperations after failed colon interposition; malformations and other pathologies of the colon and the “loose” type of blood supply to the colon. The operation of choice, in our opinion, is colon interposition, which demonstrates the best indicators of quality of life.