Article1 January 1939URINARY DIASTASE IN ACUTE PANCREATIC NECROSIS: AN EXPERIMENTAL INVESTIGATIONC. J. SMYTH, M.D.C. J. SMYTH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-7-932 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUntil recently, acute pancreatic necrosis has been considered a surgical emergency and universally regarded as an indication for immediate operation. At present the trend is toward more conservative treatment. Trasoff and Scarf1have reviewed this problem and analyzed the records of 16 patients with acute pancreatitis. Three of the four subjected to early operation died, whereas of 12 not operated upon, 9 recovered. Hartlieb2is opposed to surgical intervention, and has treated 9 patients expectantly, of whom 7 recovered. Mikkelsen3reported 39 examples of acute pancreatitis, all of which were treated conservatively with a mortality of only 7.5 per cent....Bibliography1. TRASOFFSCARF AM: Acute pancreatitis: a medical problem, Am. Jr. Med. Sci., 1937, cxciv, 470-474. CrossrefGoogle Scholar2. HARTLIEB G: Neuere Arbeiten über die operative Behandlung der akuten Pankreasnekrose bzw. der akuten Pankreatitis, Beitr. z. klin. Chir., 1933, clvii, 539-557. Google Scholar3. MIKKELSEN O: Pancreatitis acuta; schwere Fälle, besonders hinsichtlich ihrer konservativen Behandlung, Acta chir. Scandinav., 1934, lxxv, 373-415. Google Scholar4. NORDMANN O: Akute Pankreasnekrose und Cholecystitis, Chirurg., 1929, i, 721-726. Google Scholar5. ROST F: Über die Diastasewerte im Urin bei akuter Pankreasnekrose, München. med. Wchnschr., 1933, lxxx, 1971-1972. Google Scholar6. FOGED J: Diagnostic value of urine diastase, Am. Jr. Surg., 1935, xxvii, 439-446. CrossrefGoogle Scholar7. MCCAUGHAN JM: Value of estimations of amylase of blood in diagnosis of suspected pancreatic disease, Surg., Gynec. and Obst., 1934, lix, 598-609. Google Scholar8. MUSHIN M: Urinary diastase in acute pancreatitis, Australian and New Zealand Jr. Surg., 1932, ii, 133-140. CrossrefGoogle Scholar9. SCHMEIDENSEBENING VW: Surgery of the pancreas with especial consideration of acute pancreatic necrosis, Surg., Gynec. and Obst., 1928, xlvi, 735-751. Google Scholar10. COLP R: Acute pancreatitis, Ann. Surg., 1930, xci, 392-400. CrossrefGoogle Scholar11. ABELL I: Acute pancreatitis, Surg., Gynec. and Obst., 1938, lxvi, 348-353. Google Scholar12. WOHLGEMUTH J: Über eine neue Methode zur quantitativen Bestimmung des diastatischen Ferments, Biochem. Ztschr., Berl., 1908, ix, 1-9. Google Scholar13. BEIGLERMARCUS SKM: The clinical and laboratory diagnosis of acute pancreatic necrosis, Jr. Mich. Med. Soc., 1930, xxix, 289-293. Google Scholar14. FRIEDMANTHOMPSON IWR: Induced and spontaneous changes in blood amylase, Ann. Surg., 1936, civ, 388-402. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Ann Arbor, Michigan*Received for publication August 3, 1938.From the Department of Pathology, University of Michigan, Ann Arbor, Michigan. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie Krankheiten der BauchspeicheldrüseContributions made in 1939 to knowledge in regard to the pancreasRecent Advances in the Diagnosis and Treatment of Disease of the Pancreas 1 January 1939Volume 12, Issue 7Page: 932-937KeywordsAcute pancreatitisMortalityNecrosis ePublished: 1 December 2008 Issue Published: 1 January 1939 PDF downloadLoading ...