Abstract The Ordos block is a rigid portion of the North China Craton lying within the India-Eurasia collision zone that experiences little internal deformation, but is surrounded by active faulting, extensional grabens, and seismicity. In the surrounding region, geodetic studies have imaged complex crustal deformation, while seismic studies have suggested that the lithosphere is encountering regional modification by mantle convection. The Ordos block thus presents a valuable opportunity to compare seismic and geodetic constraints and investigate geodynamic processes affecting the region’s lithosphere. We here robustly image vertical land motion and horizontal strain rates using observations from the geographically extensive Global Navigation Satellite System and leveling networks in and around the Ordos block. Our results indicate that the Ordos block uplifts with some lateral variability at 0.5–2.0 mm/yr. In the northeastern Ordos block and Datong volcanic area, the crustal uplift rates are 2.0–4.0 mm/yr on average, much faster than those elsewhere on the block. We correct for non-tectonic vertical motion from surface hydrological loading and glacial isostatic adjustment, finding that these do not explain the vertical rate anomalies. Horizontal crustal extension and uplift are accompanied by a pattern of crustal contraction at the Datong volcanic field. Additionally, we find uplift west of and subsidence east of the Qinling Orogenic Belt, which are inconsistent with eastward crustal extrusion along it, suggesting instead a negligible migration of crustal materials especially to the east of 106°E. Comparing the geodetic measurements to evidence from seismic velocity anomalies and numerical simulation, we argue that the motions are consistent with lithospheric re-equilibration resulting from the heterogeneous thinning of the lithosphere by convective mantle upwelling and radial flow as well as shortening from the India-Eurasia collision.