BackgroundAtrial fibrillation (AF) is the most common arrhythmia worldwide. Data regarding 30‐day readmission following index admission for AF in the developing world are poorly described. ObjectivesThe study aimed to assess the rate, predictors, and trends of 30-day readmission after index admission for AF in Syria. MethodsWe included adult patients who had an index admission with AF to Latakia’s tertiary center between June 2021 and October 2023. Patients were monitored for readmission for 30 days after index discharge. Data were taken from patients’ medical notes. ResultsA total of 661 patients were included in the final analysis, of which 282 (43%) were readmitted to hospital within 30 days following index admission. Cardiac causes were the most common cause of readmission in 72% of patients, of which 60% were AF. Readmitted patients had a higher median age (62 vs 57; P=0.001) and fewer males (58% vs 51%; P=0.001). In multivariate analysis, factors that independently increased 30-day readmission risk were older age (HR: 1.5, 95% CI: 1.1-1.9), female sex (HR: 1.3, 95% CI: 1.02-1.4), diabetes mellitus (DM) (HR: 1.7, 95% CI: 1.3-2.3) and congestive heart failure (CHF) (HR: 2.2, 95% CI: 1.7-2.9). Most cardiac readmissions happened during the first 15 days (79%). ConclusionAlmost one in two patients were readmitted within 30 days after an index admission for AF. Female sex, advancing age, DM and CHF were independently associated with an increased risk of 30-day readmission.