Each year, approximately 40,000 Americans die in traffic crashes and almost three million are injured. In 2016, with a 90 percent national seat belt use rate, seat belts prevented 14,668 fatalities. In 2010, the medical and work loss combined cost for occupant fatalities in motor vehicle crashes was over $12 billion. Sadly, many of these fatalities, injuries, and costs could have been prevented if the victims had been wearing seat belts or were properly restrained in child seats. In 2015, only 52% of those killed in motor vehicle crashes were restrained. Despite an overall increase in seat belt use over the past decade, traffic crashes are still the leading cause of unintentional injury-related death in the United States. Primary seat belt laws have proven to be effective in increasing state’s seat belt use rate. When States upgrade their laws from secondary to primary, significant increases in safety belt use are often observed. This report will look at the National Highway Traffic Safety Administration’s Border to Border initiative aimed at addressing seat belt non-use. Border to Border (B2B) is a one-day seat belt-awareness effort coordinated by participating State highway safety offices and their respective law enforcement liaisons. The goal is to reduce seat belt fatalities in their regions by implementing the Click It or Ticket (CIOT) campaign brand. The B2B program aims to increase law enforcement participation by coordinating highly visible seat belt enforcement and providing seat belt fact sheets for drivers at heavily traveled and highly visible areas along state borders. The B2B initiative encourages cross-jurisdiction collaboration, across State borders, which will help law enforcement officers enforce seat belt laws. Since its inception in 2014, Region 2 has spearheaded the B2B program. Due to its size and success this year, NHTSA national headquarters is organizing the effort for 2018, which will include a 4-hour enforcement crackdown on May 21. This report will outline the expansion of the B2B program to a nationwide level. It will discuss state participation; engagement of law enforcement agencies, citations issued, and earned media. In addition to the results, it will look at the overall strengths and challenges of the initiative to inform future programs that require cross state collaboration by law makers, law enforcement, and public health programs globally.