Increase In Physical Activity Research Articles

Online-Based Intervention as an Effort to Increase Physical Activity Among Adolescent

Background: Physical inactivity (PA) is an important contributor to morbidity and mortality globally. Adolescence is an important period of engaging in physical activity. 2 systematic reviews before 2022 concluded that studies need more methods and evaluations to prove the continued effect of Online-based interventions. It is therefore prudent to continue this research by considering how we can approach young people to grow healthy values into their day-to-day activities. Purpose: This study aims to determine online-based interventions for physical activity in adolescents. Method: A search of the literature databases Scopus, Science Direct and Springerlink using key words ‘Adolescents’, ’Teenagers’, ’E-health’, ’Internet-based’ , ‘Online-based’, and ’Physical Activity’ limited to 5 articles which fit the criteria for inclusion. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol was used, and papers were excluded if they were disease focused, not specific to adolescents or did not measure PA as an outcome. Results: All of studies had significant increases in PA as a result of an Online-Based intervention Studies include using various implementation mechanisms. The majority of studies use a mix of web- tutorials and based lessons for participants to work on in addition to goal setting via online, app-based (4/5). That remaining studies they were given an accelerometer as a measuring device and instructed online to perform the physical activity used for the rest of the study using online forums and PA experts to emphasize the effect of goal setting. Various intervention such as giving messages about PA or Health related issues were performed few a week for about 2-3 month. Conclusion: Online-based interventions are a very successful way to increase PA. More research is required to look at what theoretical principles are best to underpin interventions and also to assess the length of intervention required for optimal results after intervention. Ideas surrounding implementation require more studies to evidence base these interventions for schools, via intracurriculum or extracurriculum.

Urban Physical Environments Promoting Active Leisure Travel: An Empirical Study Using Crowdsourced GPS Tracks and Geographic Big Data from Multiple Sources

Specific environmental characteristics can encourage active leisure travel and increase physical activity. However, existing environment-travel studies tend to ignore the differences in environmental characteristics associated with route choice and travel distance, of which the latter could be more important for health benefits, since longer trips are associated with increased exercise. Additionally, the most recent studies focus on leisure walking and leisure cycling, and activities such as hiking, climbing, and running are examined less frequently. This study, therefore, compares the similarities and differences of the environmental factors associated with route selection and travel distance through non-parametric tests and Cox proportional hazard models. The results show that two intersecting sets of environmental elements relate to both the route chosen and the distance traveled. Land use diversity and varied topography are appealing for both leisure trips and trip length. In addition, the differences in environmental characteristics among specific leisure travels may be attributed to variations in physical activity requirements, preferences for landscape viewing, and/or sensitivity to crowding. Therefore, conclusions drawn without considering the different types of leisure travel could be skewed. Whether particular surroundings may effectively increase physical activity remains uncertain. A more holistic perspective could be beneficial when studying the connection between the environment, active travel, and health.

Effect of Gamification, Financial Incentives, or Both to Increase Physical Activity Among Patients at High Risk of Cardiovascular Events: The BE ACTIVE Randomized Controlled Trial.

Physical activity is associated with a lower risk of major adverse cardiovascular events, but few individuals achieve guideline-recommended levels of physical activity. Strategies informed by behavioral economics increase physical activity, but their longer-term effectiveness is uncertain. We sought to determine the effect of behaviorally designed gamification, loss-framed financial incentives, or their combination on physical activity compared with attention control over 12-month intervention and 6-month postintervention follow-up periods. Between May 2019 and January 2024, participants with clinical atherosclerotic cardiovascular disease or a 10-year risk of myocardial infarction, stroke, or cardiovascular death of ≥7.5% by the Pooled Cohort equation were enrolled in a pragmatic randomized clinical trial. Participants received a wearable device to track daily steps, established a baseline, selected a step goal increase, and were randomly assigned to control (n=151), behaviorally designed gamification (n=304), loss-framed financial incentives (n=302), or gamification+financial incentives (n=305). The primary outcome of the trial was the change in mean daily steps from baseline through the 12-month intervention period. A total of 1062 patients (mean±SD age, 67±8; 61% female; 31% non-White) were enrolled. Compared with control subjects, participants had significantly greater increases in mean daily steps from baseline during the 12-month intervention in the gamification arm (adjusted difference, 538.0 [95% CI, 186.2-889.9]; P=0.0027), financial incentives arm (adjusted difference, 491.8 [95% CI, 139.6-844.1]; P=0.0062), and gamification+financial incentives arm (adjusted difference, 868.0 [95% CI, 516.3-1219.7]; P<0.0001). During the 6-month follow-up, physical activity remained significantly greater in the gamification+financial incentives arm than in the control arm (adjusted difference, 576.2 [95% CI, 198.5-954]; P=0.0028), but it was not significantly greater in the gamification (adjusted difference, 459.8 [95% CI, 82.0-837.6]; P=0.0171) or financial incentives (adjusted difference, 327.9 [95% CI, -50.2 to 706]; P=0.09) arms after adjustment for multiple comparisons. Behaviorally designed gamification, loss-framed financial incentives, and the combination of both increased physical activity compared with control over a 12-month intervention period, with the largest effect in gamification+financial incentives. These interventions could be a useful component of strategies to reduce cardiovascular risk in high-risk patients. URL: https://clinicaltrials.gov; Unique Identifier: NCT03911141.

88 Feasibility of a Home-based Physiotherapy Program to Increase Physical Activity Levels in Older Adults with Diabetes Mellitus

OBJECTIVES/GOALS: The objective of this study is to assess the feasibility and preliminary impact of a physiotherapy protocol for developing an individualized home-based physical activity program to increase physical activity (PA) levels in sedentary older adults with Type II Diabetes Mellitus (T2DM) living in Puerto Rico (PR). METHODS/STUDY POPULATION: This will be a pilot study with two phases. In phase 1, we will design a novel patient-centered home-based PA program protocol for adults ≥65 years with T2DM based on the Information-Motivation-Behavioral Skills model. Its content validity will be assessed through focus groups with 10 experts and 10 older adults and analyzed using a directed content analysis. Phase 2 we will be program implementation using a one-group, repeated measures design with 12 adults ≥65 years with T2DM. PA levels will be assessed by recording active minutes with a Fitbit. Risk of falls, balance, strength, and physical function will be assessed through standardized tests validated for this population. Statistical analysis will include descriptive statistics, comparisons via chi-square/Fisher’s exact test, and non-parametric tests. RESULTS/ANTICIPATED RESULTS: We expect to recruit a minimum of 12 participants and to administer the program for 12 weeks at a frequency of two visits per week. We anticipate that implementing and supervising the home-based PA protocol will be feasible as determined by recruitment and retention rates, patients’ satisfaction, and compliance with the program. We also expect that this protocol will increase physical activity levels, improve general strength, balance, physical function, and reduce the risk of falls in sedentary older adults with T2DM. DISCUSSION/SIGNIFICANCE: As the third cause of death in PR, T2DM represents a public health challenge. An effective home-based PA program may decrease morbidity and mortality rates in older adults by increasing PA and functional health. This study will provide data for planning a randomized controlled trial to assess its effectiveness in the outcomes of interest.

The ENJOY Seniors Exercise Park IMP-ACT project: IMProving older people’s health through physical ACTivity: a hybrid II implementation design study protocol

IntroductionThe health benefits of physical activity are well established; however, most older people are not sufficiently physically active. Despite the availability of various physical activity interventions and programs, implementation of effective prevention strategies to reduce older people’s physical inactivity are lacking. The ENJOY IMP-ACT project is an implementation research project, based on a previous evidence-based physical and social activity program utilising specialised outdoor exercise equipment (the Seniors Exercise Park) for older people. The ENJOY IMP-ACT aims to increase participation in physical activity to improve health outcomes for older people in Victoria, Australia.MethodThe ENJOY IMP-ACT is a hybrid II implementation-effectiveness pre-post mixed method study design. Five local governments (6 public sites/parks) will undergo a 3-month control period followed by 9-months implementation intervention (TERM framework intervention: Training, Engagement, Resources development, Marketing and promotion), and a maintenance phase (3 months). Various methodologies will be employed throughout the project at each site and will include direct observations of park users, intercept surveys with park users, online access monitor platform (using an online app), interviews with stakeholders and exercise program leaders, a process evaluation of physical activity programs, a social return-on-investment analysis, and other related activities.DiscussionThrough the implementation framework design, the ENJOY IMP-ACT is uniquely placed to translate an evidenced-based physical and social activity program into real world settings and increase physical activity among older people. If successful, this program will inform scale up across Australia with the goal of improving the health and wellbeing of older people.Trial registrationThis registration trial is prospectively registered with the Australian New Zealand Clinical Trials Registry. Trial number ACTRN12622001256763. Date registered 20/09/2022.

Abstract P212: Adherence Trends to a Remotely Supervised Weight Loss and Exercise Training Intervention to Improve Rheumatoid Arthritis Cardiovascular Risk

Introduction: Individuals with rheumatoid arthritis (RA) have an increased risk for cardiometabolic disease. By improving traditional markers of cardiometabolic health, interventions that induce weight loss and increase physical activity may also reduce RA-related cardiometabolic disease risk. However, to achieve these health benefits, an individual must adhere to such interventions. To understand whether sustained behavioral modification is feasible for individuals with RA, assessing adherence to prescribed intervention components is needed. Hypothesis: We hypothesized that adherence to a daily step goal would be greater than adherence to more intensive intervention components. Methods: Older adults with RA and overweight/obesity (n = 20) were randomized and completed 16 weeks of “usual care” Counseling Health as Treatment (CHAT) or remotely Supervised Weight loss and Exercise Training (SWET). The SWET program consisted of caloric restriction (7% weight loss goal), aerobic training (AT; 150 minutes/week), and resistance training (RT; twice weekly). Both groups were given a daily goal of 6,000 steps. Pearson correlation analyses assessed for a relationship between baseline measures and average daily step count. Results: Participants were on average 66.7 ± 5.4 years old, Caucasian (65.0%), men (80.0%), with obesity (body mass index: 32.4 ± 2.9 kg/m 2 ). For SWET and CHAT, respectively, average daily step adherence was 117.8% (7065.6 ± 2117.0 steps/day) and 118.2% (7093.4 ± 2965.4 steps/day) (Figure 1A). Average adherence to SWET-only components was 84.0 ± 0.5% for AT, 83.0 ± 0.2% for RT, and 93.9 ± 0.1% for weigh-ins (Figure 1B). Step count adherence was unrelated to baseline measures. Conclusions: Step count adherence 1) was similar in both groups despite the intervention delivery strategy, and 2) exceeded other more intensive SWET intervention components (i.e., AT and RT). Findings highlight step counts as an achievable and sustainable RA exercise goal.

The Effectiveness and Cost-Effectiveness of the ‘Walk with Me’ Peer-Led Walking Intervention to Increase Physical Activity in Inactive Older Adults: Study Protocol for a Randomised Controlled Trial

Background: The proportion of the population aged 65 years or older is increasing. Typically, physical activity and health decline with age, which is why action to promote active ageing is a major public health priority, particularly due to health inequalities in older adults. The aim of this study is to assess the effectiveness and cost-effectiveness of the Walk with Me peer-led walking intervention for older adults. Methods: This study is a two-arm, assessor-blind, randomised controlled trial. The intervention is a 12-week peer-led walking intervention based on social cognitive theory. Participants in the control group will receive information on active ageing and healthy nutrition. The study will target 348 community-dwelling older adults, aged 60 years or over living in areas of socio-economic disadvantage communities. Trained peer mentors will deliver the intervention. The primary outcome will be a mean between-group change in moderate-to-vigorous physical activity at 12 months from baseline, measured using an Actigraph accelerometer. Secondary outcomes will include quality of life, mental wellbeing, blood pressure, BMI and waist circumference. An embedded process evaluation will involve focus groups and participant diaries. Discussion: Evidence-based, cost-effective interventions to promote physical activity in older adults living in socio-economically disadvantaged communities are needed to address health inequalities.

Acceptability and Feasibility of the Telehealth Bariatric Behavioral Intervention to Increase Physical Activity Before Bariatric Surgery: A Single-Case Experimental Study (Part I).

Physical activity (PA) can play an important role in optimizing metabolic/bariatric surgery (MBS) outcomes. However, many MBS patients have difficulty increasing PA, necessitating the development of theory-driven counseling interventions. This study aimed to (1) assess the feasibility and acceptability of the TELEhealth BARIatric behavioral intervention (TELE-BariACTIV) trial protocol/methods and intervention, which was designed to increase moderate-to-vigorous intensity physical activity (MVPA) in adults awaiting MBS and (2) estimate the effect of the intervention on MVPA. This trial used a repeated single-case experimental design. Twelve insufficiently active adults awaiting MBS received 6 weekly 45-min PA videoconferencing counseling sessions. Feasibility and acceptability data (i.e., refusal, recruitment, retention, attendance, and attrition rates) were tracked and collected via online surveys, and interviews. MVPA was assessed via accelerometry pre-, during, and post-intervention. Among the 24 patients referred to the research team; five declined to participate (refusal rate = 20.8%) and seven were ineligible or unreachable. The recruitment rate was 1.2 participants per month between 2021-09 and 2022-07. One participant withdrew during the baseline phase, and one after the intervention (retention rate = 83.3%). No participant dropouts occurred during the intervention and 98.6% of sessions were completed. Participants' anticipated and retrospective acceptability of the intervention was 3.2/4 (IQR, 0.5) and 3.0/4 (IQR, 0.2), respectively. There was a statistically significant increase in MVPA [Tau-U = 0.32(0.11; 0.51)] from pre- to post-intervention. Despite a low recruitment rate, which could be explained by circumstances (COVID-19 pandemic), results support feasibility, acceptability, and preliminary efficacy of the TELE-Bari-ACTIV intervention for increasing MVPA in patients awaiting MBS.

Parent childhood experiences, parenting strategies, and youth health-related outcomes in Hispanic families with unhealthy weight: An intergenerational study

We aimed to examine whether (a) parents' childhood family mealtime experiences (CFM) (e.g., mealtime communication-based stress) and parents' socio-demographic characteristics (e.g., education level) predict parents' health-related parenting strategies (e.g., discipline), (b) health-related parenting strategies for eating and physical activity predict youth's health-related outcomes (e.g., dietary intake), (c) parenting strategies mediate the relationship between CFM and youth outcomes. A path model was used to examine the above-mentioned relationships. Data were obtained from the baseline assessment of a randomized clinical trial evaluating the efficacy of a family-based intervention to promote quality diet and increase physical activity. Participants were 280 Hispanic youth (52.1 % female, Mage = 13.01 ± 0.83) with unhealthy weight (MBody Mass Index %tile = 94.55 ± 4.15) and their parents (88.2 % female, Mage = 41.87 ± 6.49). Results indicated that childhood mealtime communication-based stress and mealtime structure were positively associated with control. Appearance weight control was positively associated with monitoring, discipline, limit-setting, and reinforcement. Parental mealtime control had positive associations with discipline, control, and limit-setting. Emphasis on mother's weight was positively associated with reinforcement. We also found positive associations between parental monitoring and youth's physical QOL and between parental discipline and fruits and vegetables intake. No mediating effect was found. Findings demonstrated significant effects of parents' childhood experience on parenting strategies, which in turn was associated with the youths' health-related outcomes. These results suggest the intergenerational effects of parent's childhood experience on their youth's health-related outcomes.

Tackling poor nutrition, lack of physical activity, and obesity in the general population

Background: Addressing the critical public health issues of poor nutrition, lack of physical activity, and obesity is essential for reducing non-communicable diseases. These factors contribute significantly to global morbidity and mortality, necessitating a comprehensive approach to improve dietary habits and increase physical activity among the general population. Methods and Materials: Utilizing an online survey targeted at medical students aged 19-25 from Kursk State Medical University, this study analyzes dietary habits, physical activity levels, and obesity perception. The survey, supplemented by academic literature and expert consultation, offers a multidimensional view of the prevailing health behaviors among students. Results: The findings indicate a concerning prevalence of unhealthy dietary choices, insufficient physical activity, and a notable perception of obesity among the participants. Statistical analysis of the survey results highlights the need for targeted interventions to address these health issues. Conclusion: The study underscores the importance of integrated strategies to promote healthy eating and regular physical activity. It calls for educational campaigns, policy measures, and individual behavioral changes to combat the growing challenge of obesity and associated health risks in the general population.

Sedentary Habits and Their Detrimental Impact on Global Health: A Viewpoint

With limited areas where people can work out, an increase in sedentary work with the growing popularity of desk jobs and television and video devices, inactive lifestyles are becoming more and more common around the world. The objective of the current review is to explore the role of sedentary habits in the causation of different diseases and their impact on global health standards. Consequently, the associated health problems are becoming more serious. Inactivity has a significant influence on the human body in numerous ways. It disrupts lipolysis, transporter proteins, muscle glucose, the metabolic process, and lipoprotein lipase functionality. Prolonged sedentary behavior directly impacts the gravity, body weight balance, and can lead to fluid retention, obesity, and an increase in oxidative stress. An inactive lifestyle has a range of adverse impacts on our bodies, including a surge in all-cause mortality, coronary heart disease mortality, and the probability of contracting diseases like diabetes mellitus, hypertension, and dyslipidemia, in addition to physical ailments like arthralgia and osteoporosis, mental health issues like depression, and mental retardation. Consequently, to advance public health, we need to reduce sedentary practices and increase physical activity.

Integrating a Gamified Digital Application in Naturebased Settings to Improve Physical Activity and Health Outcomes Among Central Pennsylvanians: Using a Socioecological, Cross-disciplinary Guiding Framework

Objectives: We evaluated the effectiveness of a community-facilitated, digital application intervention at increasing physical activity in central Pennsylvania. Methods: We employed a game-based digital application within partnership- guided, nature-based programming to encourage physical activity. Partnerships with local healthcare and park/ recreation entities were established to facilitate recruitment and intervention sustenance. Self-reported psychological and physiological changes were evaluated in a repeated-measures design, contextualized by thematic coding of qualitative responses, and interpreted via the Park Prescription Theory of Change. Results: Partnerships were formed among 3 local healthcare entities, Berks Nature, and community organizations to conduct the intervention. There were increases in physical activity duration and time spent outdoors. We identified positive, consistent trends in perceptions of healthful behaviors and quality of life, health satisfaction, and perceived accessibility and barriers. There were low rates of allergies or wheezing. The game-based application improved sentiments of belongingness and familial engagement. These findings mostly aligned with the Park Prescription Theory of Change. Conclusions: An innovative, cross-disciplinary means to improve physical activity can inform approaches at the regional or national level, as well as guide legislative efforts in public health, environmental policy, and urban planning.

Daily activity patterns in older adults receiving initial support: the association between daily steps and sitting in bouts of at least 60 min

BackgroundAging has a significant impact on health, underlining the importance of maintaining physical function and reducing time spent sitting among older adults. To understand how to reduce prolonged sitting or increase physical activity, factors related to the daily living and observed daily activity patterns should be explored. This study aimed to investigate the association between daily steps, self-rated health, physical activity, sedentary behavior, motivation to exercise and fear of falling among older adults receiving initial support.MethodCross-sectional design with total population questionnaire data from adults aged ≥ 60 years (n = 917), living at home with initial support from municipal care in southern Sweden. The older adults were offered to participate in a follow-up study measuring daily activity patterns with accelerometers (n = 72). Linear regression was used to analyze associations between daily steps and possible predictors.ResultsThe linear model (\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ {R}^{2}= $$\\end{document}0.478) showed that sitting in unbroken bouts of > 60 min (β = -0.313, p < 0.05), walking independently outdoors (β = 0.301, p < 0.05), intending to increase physical activity (β = -0.294, p < 0.05), sex (β = 0.279, p < 0.05), relative autonomy index (β = 0.258, p < 0.05), fear of falling (β = -0.238, p < 0.05), and self-rated health (β = 0.213, p < 0.05) predicted daily steps.ConclusionThe model of predictors brings new understanding regarding daily steps among community-dwelling older adults. The association between sitting in bouts of > 60 min and daily steps is interesting as 35% of participants had a number of sitting bouts that on average, showed 30% less steps taken. Minimizing long sitting bouts and maintaining physical functioning to promote independence when walking outdoors can be tools for clinical practitioners devising interventions to break prolonged sitting among community-dwelling older adults. Future research should prioritize studying older adults’ outdoor walking independence, including its relation to walking with or without assistive devices and its impact on physical activity and sedentary behavior.

Societal discrimination and mental health among transgender athletes: a systematic review and Meta-analysis

BackgroundDiscrimination and inequality have been identified as significant problems faced by transgender individuals in sports participation. However, uncertainties remain regarding the effectiveness of interventions aimed at promoting equality.ObjectivesThis systematic review and meta-analysis aimed to examine the experiences of transgender athletes in sports, focusing on mental health issues and factors contributing to inequality among transgender and other sexual minorities.MethodsThe study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and searched 10 electronic databases, including PubMed, Google Scholar, and Web of Science, to identify eligible studies published between 2005 and 2022. The search yielded 1430 articles, of which only 12 studies met the inclusion criteria for this review.ResultsThe meta-analysis of the 12 studies included in this review revealed that transgender athletes faced social discrimination and inequality in sports participation, resulting in mental health problems and higher rates of suicide. From a cohort of 21,565 participants in the studies, 7152 (33%) were subjected to discrimination in sports participation and healthcare, with a rate of 0.61 (95% confidence interval [CI]: 0.35, 0.81). However, transgender athletes who felt welcomed and embraced by their respective teams accounted for 0.39 (95% CI: 0.19, 0.65). These results indicated significant differences between how transgender athletes are treated in healthcare settings and when participating in sports.ConclusionThe study findings underscore the need for policies, cultural research, and interventions to address discrimination and inequality faced by transgender athletes in sports participation. Promoting equality and safeguarding the rights of transgender athletes can mitigate the risk of mental health problems and increase physical activity among sexual minorities.

Guidelines to conduct research in computer-prompt software studies to decrease sedentary behaviors and increase physical activity in the workplace.

Computers are ubiquitous in the workplace and facilitate prolonged sitting, which has adverse health consequences. Various computer-prompt software programs are designed to decrease sedentary behaviors and increase physical activity in the workplace. However, specific guidelines that would improve research in this area have not been published. The objective of this article is to present recommendations for improving computer-prompt software research, to decrease sedentary behaviors and increase physical activity in the workplace. Ten domains were identified based on deficiencies in the current literature combined with quality assessment tools to reduce the risk for bias. The ten domains include composition of the research team, behavioral sciences theoretical frameworks, research design, alert types, outcome measures, confounding factors, intervention duration, carryover effects, racial/ethnic composition, and organizational culture. Specific recommendations are presented for each domain. The research team should include all stakeholders contributing as copartners in designing the intervention. For theory, a systems science framework was presented. Clustered randomized controlled trials were recommended, rather than randomization at the individual level. Distinct types of alerts (visual, auditory, or both) and frequency of alerts (hourly, randomly generated, or based on prolonged sitting patterns) are described. Outcome measures include average duration of sitting bouts, longest sitting bout, and number of sitting bouts. Prolonged sitting and physical inactivity at work lead to major health problems. Adherence to the recommendations presented here should facilitate high-quality research and improve the health of desk-based workers by decreasing sedentary behaviors and increasing physical activity.

The Acti-Pair program helps men with prostate cancer increase physical activity with peer support: a mixed method pilot study.

Although the health benefits of physical activity (PA) are recognized, prostate cancer patients do not follow PA recommendations. Barriers to PA, whether physical, environmental or organizational, are known. Furthermore, even when these barriers are overcome, this achievement is not systematically accompanied by lifestyle change. Many strategies have shown to be effective in increasing patient adherence to PA. This study aims to assess the feasibility and the viability of the Acti-Pair program which combines three strategies: peer support, a personalized and realistic PA project, and support from health and adapted physical activity professionals in a local context. We conducted a pilot study utilizing a mixed qualitative and quantitative methodology, employing feasibility and viability assessments. Quantitative assessments included recruitment, retention adherence rates, process and potential effectiveness (PA and motivation) indicators; while qualitative methods were used to evaluate the program's practicality, suitability and usefulness. Indicators of potential effectiveness were assessed before and after the intervention using a Wilcoxon test for matched data. Qualitative data were collected through semistructured interviews conducted by two researchers with various program stakeholders. The study lasted for 3 years. Twenty-four patients were recruited over a 25-month period. Forty-two percent of patients completed the program 3 months after the beginning. We recruited 14 peers and trained nine peers over a 10-month period. The program was coordinated extensively by adapted PA professionals, while health professionals were involved in recruiting patients and peers. Self-reporting of moderate to vigorous PA was increased after the Acti-Pair program initiation [42.86 (30.76) at baseline to 53.29 (50.73)]. Intrinsic motivation significantly increased after participation in the Acti-Pair program [1.76 (1.32) before the intervention vs. 2.91 (1.13) after the intervention]. The key player to support the Acti-Pair program in the field has been the PA support system. The main challenge has been the difficulty of health professionals in promoting PA. This pilot study has shown that the Acti-Pair program is feasible and viable. It will allow us to extend the peer support intervention to other contexts and assess the effectiveness of this intervention and its generalization.

Suggestions on prevention throughout whole life cycle to curb the rapidly increasing prevalence of noncommunicable diseases in the population

Chronic non-communicable diseases (NCDs) have become diseases that seriously threaten the health and quality of life of the Chinese population, and also become a major public health problem affecting the national economic and social development. With the intensification of China's population aging, the economic burden caused by NCDs will further increase. More and more evidence has shown that NCDs could be prevented, and the prevention and control of NCDs have been considered as a core task of building a healthy China. Therefore, precise personalized nutrition and the prevention of NCDs from the age of zero, which is called the "Double Zero Strategy", would provide a well-consolidated basis for body tissue structure, and prevention of NCDs should also begin at age zero, and then extend to the first 1 000 days of life. The "Double Zero Strategy" preventive intervention can improve the nutritional status, balance diet and nutrition, and increase physical activity among children, adolescents, adults, and the elderly, all of which can reduce the risk of chronic disease, disability, and death. Therefore, launching the "Double Zero Strategy" for full life cycle prevention will help to achieve China's health goals in the new era, and provide more comprehensive measures and plans for implementing the goal of a healthy China.

Medication Adherence and Physical Activity in Relation to Blood Pressure in Hypertension Patients

In the 21st century, it is estimated that there will be a rapid increase in the incidence and prevalence of NCDs. It is estimated that the countries that will feel the impact the most are developing countries, including Indonesia. One of the NCDs that is currently a very serious health problem is hypertension. This study aims to determine the relationship between medication adherence and physical activity on blood pressure in hypertension patients. This research is an analytical study with a cross-sectional design. Data collection was carried out by conducting interviews with patients, filling out questionnaires by the patient, viewing the patient's medical record data and carrying out blood pressure checks in September 2023 to October 2023. Bivariate analysis showed that there was an influence of medication attendance (p value = 0.0001; PR = 7.667) and physical activity (p value = 0.0001; PR = 26.156) on blood pressure. Multivariate analysis showed that physical activity (p value = 0.0001; aPR = 23.726) had more influence on blood pressure than medication adherence (p value = 0.007; aPR = 6.622). It is important for health workers to always educate patients regarding medication compliance and increase physical activity in an effort to achieve normal blood pressure.

THE INTERTISSUE COMMUNICATION BETWEEN THE HYPOTHALAMUS AND WHITE ADIPOSE TISSUE IN MAMMALIAN AGING AND LONGEVITY CONTROL

Abstract Recent studies in model organisms have demonstrated that the intertissue communications play a critical role in the regulation of aging and longevity. Our major goal is to understand the systemic regulation of aging and longevity in mammals and translate that knowledge into an effective anti-aging intervention that could make our later lives as healthy and productive as possible (“productive aging”). In mammals, we have previously demonstrated that the intertissue communication between the hypothalamus and adipose tissue, particularly mediated by extracellular vesicles-contained extracellular nicotinamide phosphoribosyltrasferase (eNAMPT), the rate-limiting NAD+ biosynthetic enzyme in mammals, functions to counteract age-associated physiological decline and promote longevity in mice. We have recently found that Ppp1r17-positive neurons in the dorsomedial hypothalamus (DMHPpp1r17 neurons) regulate white adipose tissue (WAT) function, including lipolysis and eNAMPT secretion, through the sympathetic nervous system (SNS), and the feedback loop between DMHPpp1r17 neurons and WAT plays a critical role in the regulation of aging and longevity in mice. Within DMHPpp1r17 neurons, the phosphorylation and subsequent nuclear-cytoplasmic translocation of Ppp1r17, regulated by cGMP-dependent protein kinase (PKG; Prkg1), affect gene expression regulating synaptic function, causing synaptic transmission dysfunction and impaired WAT function. Both DMH-specific Prkg1-knockdown, which suppresses age-associated Ppp1r17 translocation, and the chemogenetic activation of DMHPpp1r17 neurons significantly ameliorate age-associated WAT dysfunction, increase physical activity, decrease age-associated mortality rate, and extend lifespan. Thus, these findings clearly demonstrate the importance of the intertissue communication between the hypothalamus and WAT in mammalian aging and longevity control and provide critical insights into the development of effective anti-aging interventions.

A Literature Review: Applying Behavioral Change Theory to Promote Sedentary Behavior Reduction and Physical Activity Among Truck Drivers

Sedentary behavior has become a major cause of several diseases. Commercial drivers are at risk of high levels of sedentary behavior, especially truck drivers. Working conditions are an important barrier to healthy behaviors. The total sitting time for truck drivers might be higher than for other occupations. Limited evidence exists of the total sitting time for truck drivers. Therefore, interventions to reduce sedentary behaviors and increase physical activity are needed among truck drivers. The objectives of this article are 1) to review the theory-guided intervention in truck drivers and 2) to describe and provide an example of intervention using an integrated behavior model for reducing sedentary behaviors and increasing physical activity. The review found diverse interventions aimed at reducing sedentary behavior and promoting physical activity across age groups (children, adolescents, adults, or older adults) and settings (community, hospital, or worksite), addressing various health conditions. Delivery methods, including face-to-face and online approaches, vary. These interventions typically incorporate multiple components such as health education, self-monitoring, behavioral targets, or goal-setting. The principal guiding theories are social cognitive theory and the transtheoretical model. The integrated behavior model can serve as a guiding framework for interventions targeted at truck drivers, and the results may be utilized for other commercial drivers.