Increased Intake Of Vitamin Research Articles

Modification of Dietary Habits for Prevention of Gout in Japanese People: Gout and Micronutrient Intake or Alcohol Consumption

In Japan, most of gout patients are adults, and the prevalence of gout has increased markedly since the 1960s. This phenomenon is thought to be attributed to the westernization of the Japanese diet since 1955. Monitoring the intake of nutrients and foods in Japanese people is essential in the prevention of gout. The objective of this article is to propose a preventive method for gout through the evaluation of recent dietary habits in Japanese people. In this article, the author suggests the importance of micronutrient (vitamin and mineral) intake and alcohol consumption for prevention of gout in Japanese people referencing the results of clinical research reported. The author used the data of the Comprehensive Survey of Living Conditions in Japan for the number of gout patients (1986-2016) and the data of the National Health and Nutrition Survey in Japan (1946-2017) for the intake of micronutrients. The relationship between the number of gout patients and micronutrient intake in Japanese people was examined. Modification of micronutrient intake for the prevention of gout in Japanese people (especially adults) is suggested as follows: limiting or decreasing salt intake; increase intake of vitamin A, vitamin B₁, vitamin B₂, vitamin B₆, calcium, potassium, magnesium, and zinc; and limiting alcohol consumption.

Inadequate vitamin D level: association with low energy fractures of distal radius in young patients and its predictors in Karachi, Pakistan

<p class="abstract"><strong>Background:</strong> The objective of the study was to determine association of inadequacy of vitamin D level with low energy fractures of distal radius and its predictors in young patients in Karachi Pakistan.</p><p class="abstract"><strong>Methods:</strong> Cross-sectional study was conducted on 220 young patients, visited hospital with low energy fracture of distal radius. A questionnaire was designed and filled after taking consent includes details regarding age, gender, occupation, area of skin and sun exposure duration, dietary habits, type of clothing and residence used. Serum Vitamin D3 levels were determined and compared with serum calcium levels, serum phosphorus and alkaline phosphatase levels. </p><p class="abstract"><strong>Results:</strong> Among 220 patients ranging from 12-45 years, mean 28±23.33 SD. Female were 172 (78.18%). Mostly have history of fall 127 (57.72%) and RTA 63 (28.63). Sun exposure duration in majority of participant was 1-2 hour/day 132 (60%). Variable coloured clothes used by majority participant 135 (61.36%) and variable fabric 102 (46.36%). 202 (91.8%) patients had deficiency of vitamin D and correlated with duration of sunlight exposure significantly, also with exposure of large skin area, dietary consumption of vitamin D rich food and worn variable clothing colours. Serum phosphorus level and serum alkaline phosphatase level were negatively correlated with vitamin D significantly whereas positively correlated with serum calcium.</p><p class="abstract"><strong>Conclusions:</strong> Prevalence of vitamin D deficiency is very high in low energy fracture of distal radius in young population and sun exposure duration found to be most common predictor of inadequate D levels. A national food fortification program and campaign of public awareness to increase sunlight exposure and increase intake of vitamin D rich food are urgently needed.</p>

Correlation analysis of blood lipid level and nutritional status of elderly in Wuhan city

Objective To explore the relationship between blood lipid level and nutritional status of the aged population in Wuhan. Methods A total of 1 634 elderly people who had taken physical examinations between December 2015 and December 2016 were selected as the research objects.Medical examination and dietary structure investigation were carried out successively.The blood test results were recorded, and the dietary structure and the nutrient intake of hyperlipidemia patients and normal population, and the correlation between nutrient intake and the lipid levels were analyzed. Results Among the 1 634 elderly people, 632 were found as hyperlipidemia patients, and the levels of high density lipoprotein (HDL) cholesterol, total cholesterol (TC) and triglyceride (TG) of the male ones were shown to be significantly lower than female, with diastolic blood pressure (DBP) increased significantly, and the differences were statistically significant (P 0.05). The intake of milk, fish, fruits, vegetables, beans and bean products, and nuts of the elderly people was significantly less than the recommended intake, and the content of salt, edible oil, meat, cereals and potatoes were significantly increased, with statistically significant difference (P<0.05). Vitamin A, fat, protein and energy in the hyperlipemia group were increased significantly compared with normal group, yet the vitamin C intake was significantly reduced, and the differences were statistically significant (P<0.05). The higher the vitamin A, fat and protein, the greater the likelihood of occurrence of hyperlipidemia (P<0.05), and the higher the level of vitamin C, the smaller the likelihood of occurrence of hyperlipidemia (P<0.05). Conclusions Unbalanced diet is the leading cause of elevated blood lipid levels.The increasing intake of vitamin C and the reduced intake of vitamin A, protein and energy, improved dietary habits, and regular examinations can help to reduce the blood lipid levels. Key words: The aged; Blood lipid level; Nutritional status; Dietary survey; Protein

Cataract Forestalling by Antioxidant Activity of Vitamin C; Amelioration of Cataract by Nutritional Intervention

Cataract is the ocular disease that lessens the vision by making the lens opaque. It is a dysfunction of the lens resulting from opacification, which impedes the transmission of light. Oxidative stress is the main culprit of this disease which leads to clouding of the human lens. The prevention of the oxidative stress and other factors that worsen this disease can be minimizing by the intake of vitamin c and its anti-oxidative activity is helpful in reducing its outbreak in future. Whereas increase intake of vitamin C in the diet may have increases the availability in the fluid around the lens, providing extra protection.

Modest reversal of metabolic syndrome manifestations with vitamin D status correction: a 12-month prospective study

Numerous cross-sectional studies have noted significant negative associations between circulating levels of 25-hydroxyvitamin D and cardiometabolic risk factors, highlighting potential extraskeletal functions of this sterol hormone. Prospective studies, however, have been limited; and hence, no cause-and-effect relations can be inferred. This study aims to determine whether vitamin D status correction can reverse already established manifestations of the metabolic syndrome (MetS). A total of 59 adult nondiabetic, overweight, and obese Saudis (31 male, 28 female) were prospectively enrolled in this 1-year interventional study. Anthropometry and biochemical evaluation were performed, including determination of serum 25-hydroxyvitamin D, calcium, and phosphorous concentrations, as well as fasting blood glucose and lipid profile. Subjects were advised to regularly expose themselves to sunlight and increase intake of vitamin D–rich foods. All measurements were repeated 6 and 12 months later. At the initial baseline visit, the prevalence of both low high-density lipoprotein cholesterol and hypertension was significantly increased among patients with 25-vitamin D deficiency (P < .05), even after adjusting for sex and body mass index. Overall prevalence of MetS patients by the modified National Health and Nutrition Examination Survey Adult Treatment Panel III definition decreased from 25.2% to 13.0%; and this was largely due to a parallel decrease in the prevalence of low high-density lipoprotein cholesterol, triglycerides, and hypertension. Optimization of vitamin D status through sun exposure and increased intake of a vitamin D–rich diet can lead to an improved cardiometabolic profile, offering a promising nonpharmacologic approach in the prevention of MetS manifestations.

Association between metabolic syndrome (MetS) and serum Vitamin D concentrations in rheumatoid arthritis

Numerous cross-sectional studies have noted significant negative associations between circulating levels of 25-hydroxyvitamin D and cardiometabolic risk factors, highlighting potential extraskeletal functions of this sterol hormone. Prospective studies, however, have been limited; and hence, no cause-and-effect relations can be inferred. This study aims to determine whether vitamin D status correction can reverse already established manifestations of the metabolic syndrome (MetS). A total of 59 adult nondiabetic, overweight, and obese Saudis (31 male, 28 female) were prospectively enrolled in this 1-year interventional study. Anthropometry and biochemical evaluation were performed, including determination of serum 25-hydroxyvitamin D, calcium, and phosphorous concentrations, as well as fasting blood glucose and lipid profile. Subjects were advised to regularly expose themselves to sunlight and increase intake of vitamin D–rich foods. All measurements were repeated 6 and 12 months later. At the initial baseline visit, the prevalence of both low high-density lipoprotein cholesterol and hypertension was significantly increased among patients with 25-vitamin D deficiency (P < .05), even after adjusting for sex and body mass index. Overall prevalence of MetS patients by the modified National Health and Nutrition Examination Survey Adult Treatment Panel III definition decreased from 25.2% to 13.0%; and this was largely due to a parallel decrease in the prevalence of low high-density lipoprotein cholesterol, triglycerides, and hypertension. Optimization of vitamin D status through sun exposure and increased intake of a vitamin D–rich diet can lead to an improved cardiometabolic profile, offering a promising nonpharmacologic approach in the prevention of MetS manifestations.