The ternary NiTi+3Cu parts were produced using selective laser melting (SLM) with the addition of 3 wt% Cu nanoparticles. The incorporation of Cu nanoparticles resulted in the precipitation of nano-sized Ti2Cu second phase, the refinement of B2 matrix, the elimination of texture, and a transition from columnar to equiaxed grains. The SLM-fabricated NiTi+3Cu parts exhibited excellent antibacterial properties, achieving an antibacterial rate of 70.83 % due to the persistent release of Cu ions. The NiTi+3Cu deposits demonstrated stable tensile performance in both the transverse and longitudinal directions, and they performed better than their NiTi counterparts, primarily due to the effects of B2 grain refinement and the presence of nano-sized Ti2Cu precipitates. As the B2 phases transformed from columnar to equiaxed grains, the anisotropic rate of ultimate tensile strength and elongation to fracture was reduced from 16.3 % to 1.64 % and 16.1–3.07 %, respectively. Furthermore, the wear resistance was also enhanced by the incorporation of Cu nanoparticles, and the wear mechanism shifted from abrasive to delamination wear. These findings indicate that the crack-free ternary NiTi+3Cu shape memory alloys can be fabricated using SLM, synchronously achieving excellent antibacterial, mechanical, and wear properties through microstructural tailoring.