Purpose: Video capsule endoscopy (VCE) completion rates have varied from <10% to >30% for patients undergoing SB capsule endoscopy. Completion rates in hospitalized patients specifically have yielded inconsistent results, often with high incomplete rates, felt to be related to acute or confounding medical issues. We set out to determine incomplete rates in hospitalized patients undergoing small bowel VCE. Methods: Retrospective review of 113 inpatients undergoing VCE between 2008 and 2011 in an inpatient, community based hospital, using the Given Imaging Pillcam® SB2 capsule. Procedures were performed only during the daytime, using the standard ingestion protocol (liquid dinner, NPO afer midnight). No preps or prokinetics were used. All hospitalized patients were ambulated when medically feasible. No control for medications, such as anticholinergics, narcotics, laxatives or other bowel active medications. Age, sex, study indications, transit times, including completeness of capsule studies were reviewed and recorded. Results: 113 patients undergoing VCE had the complete study performed, with 9 patients having the capsule placed endoscopically. In all studies, VCE was performed after EGD/colon and radiographic studies, during the acute hospitalization. In 16 of the total 113 studies, the capsule did not reach the cecum, for a total incompletion rate of 14.2%. Indications for VCE included bleeding (66%), suspected IBD(11%), IDA(15%) and other (suspected tumor, intussception, suspected SB varices, previous SB surgery). In 11 of the 16 incomplete studies, the capsule remainded in the stomach, or had proglonged gastric emptying time preventing complete small bowel visualization. In 8/11 (73%) of these patients, past medical histories were positive for conditions that can cause gastric retention, including diabetes (4 patients), h/o mild gastroparesis (1pt), h/o proximal small bowel partial obstruction (2 pts), and hypothyroidism (1pt). Three of the 11 patients with gastric retention had been on opioid analgesics, and overall, a total of 9/11 patients (82%) had either a past medical history or medication that could explain prolonged gastric emptying or gastric retention. In the five remaining incomplete studies, the incomplete studies were due to prolonged SB transit in three patients, strictures in two. Conclusion: Our data suggests that performing VCE in hospitalized inpatients does not result in higher than expected incomplete small bowel examination completion rates (14.2%). Gastric retention and delayed gastric emptying appears to be the major contributory factor for incomplete examinations. Therefore, patients may be prescreened for the potential use of prokinetic agents or for endoscopic placement if these factors are present. Disclosure: Dr. Schmelkin- Consultant: Given Imaging.