Incidental Activity Research Articles

Third place visits and associations with walking habit formation: an exploratory study extending Cognitive Chrono-Ethnography

ABSTRACT Third places play a crucial role in urban environments, acting as social spaces distinct from the home and workplace, contributing to citizens’ social and physical health. However, it remains unknown how they contribute to the formation of walking habits during different life phases. Therefore, this conceptual study explores the role of third places for students (n = 3), workers (n = 6), and retirees (n = 2). Building upon past studies that utilized Cognitive Chrono-Ethnography, a mixed-method approach examining people’s in-situ behaviour and decision-making processes, semi-structured interviews questioned the role of third place visits in the process of forming walking habits. The study revealed that students, workers, and retirees may display distinct patterns of walking habits. Moreover, three goal structures were identified, where walking was either considered as a primary goal alongside third place visits, as a secondary goal, or encountered as an incidental activity during third place visits. Furthermore, participants residing in areas with higher walkability were more likely to consciously engage in walking during third place visits. These findings lay the foundation for broader investigations employing the CCE methodology to consolidate and develop the findings made in this conceptual study and promote walking habit formation through third place visits.

Time to Elicit Physiological and Exertional Vigorous Responses from Daily Living Activities: Setting Foundations of an Empirical Definition of VILPA.

Vigorous intermittent lifestyle physical activity (VILPA) are bursts of incidental vigorous activity that occur during day-to-day activities outside of the exercise-domain. VILPA has shown promise in lowering risk of mortality and chronic disease. However, there is an absence of an empirically derived definition. Using physiological and effort-based metrics commonly used to define vigorous intensity, we investigated the minimum time needed to elicit physiological and perceived exertion responses to standardised activities of daily living. Seventy adults (Age = 58.0 ± 9.6y; 35 female) completed 9 VILPA activities of daily living in a randomised order, that included: fast walking, fast incline walking, stair climbing, stationary cycling, and carrying external weight equal to 5% and 10% of body weight. Metabolic rate (by continuous indirect calorimetry), heart rate (telemetry) and perceived effort (Borg Scale) were measured during exercise. Time to reach VILPA was assessed using %VO2max, %HRmax, and rating of perceived exertion thresholds. The mean time to elicit VILPA ranged from 65-95 seconds (mean ± sd = 76.7 ± 3.8 seconds) for %VO2max, 68 to 105 seconds (mean ± sd = 82.8 ± 6.8 seconds) for %HRmax, and 20 to 60 seconds (mean ± sd = 44.6 ± 6.7 seconds) for rating of perceived exertion. For each of the three indices, there was no difference in the time to elicit VILPA responses by sex or age (p > 0.08), and times were also consistent between activities of daily living tasks. For example, for females and males, the average time to elicit vigorous responses while walking on a flat surface was 85.8 (±16.9) and 80 (±13.9) seconds, respectively, and for stair climbing while carrying 10% of body weight the duration was 78.4 (±17.6) and 76.9 (±17.7) seconds. When participants undertook activities of daily living, VILPA elicited a physiological response at an average of 77-83 seconds for %VO2max and %HRmax, and 45 seconds for perceived exertion. The absence of a difference in the time to reach VILPA between sex and age suggests that a consistent behavioural VILPA translation can be used in interventions and population-based studies designed to assess the health effects of incidental physical activity.

‘It's just one step too far’: Negotiating physical activity for perinatal mental health

BackgroundPhysical activity is recommended as a self-help strategy for some mild to moderate perinatal mental illnesses. Despite this, we know very little about how women remain active, or take up physical activity, in the context of changing family life and perinatal mental illness. We seek to explore: a) how women negotiate physical activity for their mental health during transitions into parenthood and the early years; and b) the experiences of women with perinatal mental illness in relation to physical activity. MethodsAn anonymous UK-wide qualitative online survey was used to better understand how physical activity may be used for perinatal mental health, barriers to activity and changes over time. 186 women with babies and children up to four years completed the survey. Reflexive thematic analysis was used to analyse the qualitative data and generate themes. ResultsThemes generated from this data were: 1) negotiating being active for perinatal mental health (the benefits and how these women remained active); 2) barriers to PA associated with mental illness (some women were active but still experienced general barriers to further PA, and there were several emotional barriers from mental illness); and 3) PA, guilt and the importance of valuing walking (guilt about not being active enough, guilt and feelings of failure exacerbated by questions about PA levels without support offered; regular walking not valued as PA exacerbating feelings of guilt). Conclusions and ImplicationsThis study provides new empirical data on the experiences of new mothers’, physical activity and mental health with important implications for physical activity messaging and support for women during this time through maternity care. Individualised conversations are important and the value of walking and incidental activity from activities that mothers and families find enjoyable should be promoted.

Seasonal differences in mobility and activity space in later life: a case study of older adults in the Northern Netherlands

Mobility is crucial for maintaining well-being in later life. Previous research has shown that older adults’ mobility fluctuates throughout the day, with a particular focus on afternoon outdoor movement. This paper takes a broader approach and explores the seasonal differences and similarities in mobility and activity space in later life, using older adults in the Northern Netherlands as a case study. Seventeen older adults participated in the study, for which we used a mixed-methods approach combining GPS-, activity diaries, and in-depth interview data analysed through grounded visualisation. We have collected data from each participant for a week, once during fall/winter and once during summer. The findings of this paper defy common expectations around older adult mobility; for instance, the participants walked less in summer and had a larger activity space in winter. Equally, we demonstrate that it is crucial to distinguish between daily and incidental activity spaces, particularly when factoring in seasonal variations. Yet our mixed-methods approach revealed discrepancies between perceived and measured mobility and activity space. We argue that the intricate interplay of seasonal influences, weather conditions, and personal factors significantly shapes mobility practices in later life, underscoring the need for holistic planning of age-inclusive environments.

The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux and macrophage-induced rifampicin tolerance

Tuberculosis treatment requires months-long combination chemotherapy with multiple drugs, with shorter treatments leading to relapses. A major impediment to shortening treatment is that Mycobacterium tuberculosis becomes tolerant to the administered drugs, starting early after infection and within days of infecting macrophages. Multiple lines of evidence suggest that macrophage-induced drug tolerance is mediated by mycobacterial drug efflux pumps. Here, using assays to directly measure drug efflux, we find that M. tuberculosis transports the first-line antitubercular drug rifampicin through a proton gradient-dependent mechanism. We show that verapamil, a known efflux pump inhibitor, which inhibits macrophage-induced rifampicin tolerance, also inhibits M.tuberculosis rifampicin efflux. As with macrophage-induced tolerance, the calcium channel-inhibiting property of verapamil is not required for its inhibition of rifampicin efflux. By testing verapamil analogs, we show that verapamil directly inhibits M. tuberculosis drug efflux pumps through its human P-glycoprotein (PGP)-like inhibitory activity. Screening commonly used drugs with incidental PGPinhibitory activity, we find many inhibit rifampicin efflux, including the proton pump inhibitors (PPIs) such as omeprazole. Like verapamil, the PPIs inhibit macrophage-induced rifampicin tolerance as well as intramacrophage growth, which has also been linked to mycobacterial efflux pump activity. Our assays provide a facile screening platform for M. tuberculosis efflux pump inhibitors that inhibit invivo drug tolerance and growth.

THE CULTURAL ADAPTATION, RELIABILITY AND VALIDITY OF THE TURKISH VERSION OF THE SIMPLE PHYSICAL ACTIVITY QUESTIONNAIRE IN COMMON MENTAL DISORDERS

Purpose: This study aims to evaluate the validity and reliability of the Turkish version of the Simple Physical Activity Questionnaire (SIMPAQ-T) in patients with common mental disorders.
 Methods: A total of eighty-one patients (mean age: 40.14±13.05 years) were included in this study. The SIMPAQ-T was used to evaluate the participants' physical activity levels and sedentary behaviors. To be used as descriptive data, DSM-5 Level 1 Cross-Cutting Symptom Measure-Adult was used to evaluate mental health symptomatology. International Physical Activity QuestionnaireShort Form (IPAQ-SF) and Brief Psychiatric Rating Scale (BPRS) were used to test the validity of the questionnaire.
 Results: The items of the SIMPAQ-T exhibited excellent intercorrelation coefficient (ICC) values (time spent in bed (0.93 (95% CI: 0.90-0.96)), sedentary time 0.87 (95% CI: 0.80-0.92), walking time 0.98 (95% CI: 0.98-0.99), exercise time 0.99 (95% CI: 0.99-0.99), and incidental activity time 0.95 (95% CI: 0.92-0.97)). The SIMPAQ-T was moderately correlated with IPAQ-SF in terms of sedentary (rho=0.641, p=0.001) and walking time (rho=0.564, p=0.001), indicating good construct validity. However, the BPRS had a significant correlation with only the sedentary time of the SIMPAQ (rho=0.246, p=0.022), indicating convergent validity was poor.
 Conclusion: The SIMPAQ-T is semantically and linguistically adequate to quickly assess physical activity level and sedentary behavior in patients with common mental disorders.

Evidence that heat acclimation training may alter sleep and incidental activity

ABSTRACT This randomized cross-over study tested the hypothesis that heat acclimation training would detrimentally affect sleep variables and alter incidental physical activity compared to a thermoneutral training control condition. Eight recreationally trained males (V̇O2peak 49±4.9 mL.kg-1.min-1) completed two separate interventions separated by at least 31 days: 5 consecutive day training blocks of moderate-intensity cycling (60 min·day-1 at 50% peak power output) in a hot (34.9±0.7 °C and 53±4 % relative humidity) and a temperate (22.2±2.6 °C; 65±8 % relative humidity) environment. Wrist-mounted accelerometers were worn continuously for the length of the training blocks and recorded physical activity, sleep quality and quantity. Data were analysed in a Bayesian framework, with the results presented as the posterior probability that a coefficient was greater or less than zero. Compared to the temperate training environment, heat acclimation impaired sleep efficiency (Pr β<0 = .979) and wake on sleep onset (Pr β>0 = .917). Daily sedentary time was, on average, 35 min longer (Pr β>0 = .973) and light physical activity time 18 min shorter (Pr β>0 = .960) during the heat acclimation period. No differences were observed between conditions in sleep duration, subjective sleep quality, or moderate or vigorous physical activity. These findings may suggest that athletes and coaches need to be cognisant that heat acclimation training may alter sleep quality and increase sedentary behaviour. Highlights Five consecutive days of heat training negatively affected some objective measures of sleep quality and incidental physical activity in recreationally trained athletes. Athletes and coaches need to be aware of the potential unintended consequences of using heat acclimation on sleep behaviours.

Associations Between Planned Exercise, Walking, Incidental Physical Activity, and Habit Strength in Older People: A Cross-Sectional Study.

Habits play an important role in physical activity (PA) engagement; however, these associations in older people are not well understood. The present study aimed to investigate the relationship between engagement in types of PA and their automaticity in older people, using an observational, cross-sectional design. Current hours engaged in planned exercise (excluding walking), planned walking, and incidental activities and the automaticity of those PA behaviors were measured in 127 community-dwelling Australians aged 65 years and older via an online questionnaire. After controlling for demographic and health factors (age, gender, education level, body mass index, history of falls, and anxiety and depression symptoms), higher automaticity scores were associated with more hours undertaking planned walking and incidental activity but not planned exercise. Although preliminary, these findings indicate that the role of habit in maintaining PA in older people may, therefore, differ depending on the type of activity.

Young women's engagement with gambling: A critical qualitative inquiry of risk conceptualisations and motivations to gamble.

Younger women's engagement with gambling has changed over recent decades due to a range of socio-cultural, environmental and commercial factors. However, younger women's distinct lived experiences with gambling have rarely been considered. The following critical qualitative inquiry explored factors that influenced younger women's engagement with gambling and their perceptions of gambling risks. Semi-structured interviews were conducted with 41 Australian women aged 18-40 years. Participants were asked questions relating to their reasons for gambling, and the perceived risks associated with gambling. Reflexive thematic analysis was used to interpret the data. Five themes were constructed from the data. First, women reported that they gambled to escape their everyday lives, with some women reporting gambling within their own homes. Second, women reported gambling for financial reasons, particularly to change their life circumstances and outcomes. Third, gambling was used by women as a way to connect with social network members. Fourth, gambling was an incidental activity that was an extension of non-gambling leisure activities. Finally, lower risk perceptions of participants' own gambling risk contributed to their engagement and continuation of gambling. Public health and health promotion initiatives should recognise that young women's gambling practices are diverse, and address the full range of socio-cultural, environmental and commercial factors that may influence younger women's engagement with gambling.

Short Daily-Life Walking Bouts and Poor Self-Reported Health Predict the Onset of Depression in Community-Dwelling Older People: A 2-Year Longitudinal Cohort Study.

This study aimed to assess whether the amount and quality of daily-life walking obtained using wearable technology can predict depression onset over a 2-year period, independently of self-reported health status. Longitudinal cohort study. Three-hundred twenty-two community-dwelling older people recruited in Sydney, Australia. Participants were assessed at baseline on (1) depressive symptoms using the Patient Health Questionnaire-9; (2) average weekly physical activity levels over the past month using the Incidental and Planned Activity Questionnaire, (3) clinical mobility tests (ie, short physical performance battery, timed up-and-go test, 6-m walk test); and (4) amount and quality of daily-life walking assessed with a trunk accelerometer (MoveMonitor, McRoberts) for 1week. Participants were followed up for onset of depressive symptoms for 2years at 6-monthly intervals. Daily-life walking (ie, gait intensity in the mediolateral axis, daily step counts, duration of longest walk) and self-rated health predicted the new onset of depressive symptoms at 2years in univariable logistic regression models. In multivariable models containing a self-rated health measure, clinical mobility tests were not predictive of the onset of depressive symptoms. In contrast, a measure of daily-life walking (duration of longest walking bout) was identified as a significant predictor of depressive symptom onset [standardized odds ratio (SOR) 2.44, 95% CI 1.62-3.76] independent of self-rated health (SOR 1.51, 95% CI 1.16-1.96), with these 2 measures achieving a satisfactory prediction accuracy (area under the curve= 0.67, sensitivity: 0.78, specificity: 0.52). A risk algorithm based on daily-life walking bouts and self-reported health demonstrated good accuracy for the prediction of depression onset in older people over 2years. Wearable sensor data compared favorably with clinical mobility screens and may add important independent information for screening for depression among older people.

Photography in the Arctic Archipelago during the First International Polar Year, 1882–1883

August 1, 1882, marked the start of the First International Polar Year, IPY-1, when natural science researchers conducted observations from stations positioned across the Arctic and Antarctic. IPY-1 took place as photography increasingly played a part in Arctic exploration, and with the polar year came an opportunity to further photographic experimentation and the emerging photographic documentation of Arctic lands. Here, I do a first review of the use of photography during three IPY-1 expeditions to the Arctic Archipelago, arguing that focused and strategic planning was key to the development of Arctic photography from an almost incidental expedition activity to a ubiquitous pursuit for images.

Exploring the impact of public transport including free and subsidised on the physical, mental and social well-being of older adults: a literature review

ABSTRACT Physical activity is one of the most important interventions to improve the health and well-being of populations. Gaining sufficient physical activity can often be difficult for older people, who are less likely to be involved in formal exercise. Older people are also more likely to suffer from social isolation. Active transport is an ideal opportunity to increase both the physical and social well-being of older populations. This literature review investigates the impact of public transport on the health and well-being of older adults and discusses policy implications. A literature search was conducted in CINAHL, Medline, Scopus, Web of Science and ProQuest Social Science databases to identify relevant articles. Fifty-eight articles were identified. Despite the prevalence of public transport including free and subsidised services worldwide, there is only a small body of research on the impact on older people. While limited, the literature on free and subsidised public transport and older people highlights that access has clear benefits for health and well-being. Public transport both promote active transport by encouraging older people to incorporate incidental activity into daily routines. We review literature showing that active transport positively affects older people’s physical health, as well as their mental health by enabling them to maintain social networks, thus reducing social isolation.

Do Automatic Habits Predict Physical Activity Engagement in Older People?

Sufficient physical activity is crucial to maintaining independence, health and wellbeing during ageing, yet physical inactivity is common in older people. Identifying factors associated with physical activity engagement is essential to develop novel approaches to increase activity in older people. Automatic, context-dependent habits may play an important role in physical activity behaviour. The current study aimed to investigate the relationship between physical activity behaviours and their automaticity in older people. 123 community dwelling Australians aged over 65 – 88 years (M=72.2; 81 women), recruited from participant registries, hospital noticeboards and community groups, completed an online questionnaire. Current physical activity levels were measured using the Incidental and Planned Exercise Questionnaire, and automaticity of those physical activity behaviours were measured using the Self-Report Habit Automaticity Index. Participants also reported demographic information, body mass index (BMI), medical history and current mood symptoms. Participants reported an average of 2.28 hours planned walking (SD=2.33), 5.81 hours planned moderate/vigorous exercise (SD=4.02), and 20.5 hours incidental activity (SD=15.52) per week. Multiple regression analyses revealed that after controlling for age, gender, BMI and depression symptoms, higher automaticity scores were associated with more hours per week of planned walking (p=.012), moderate/vigorous exercise (p=.038), and incidental activity (p=.017). Supporting older people to make their physical activity more habitual could therefore be an effective approach to increase levels of physical activity in this population.

The role of automatic habit in physical activity behaviours in older people: A new target for lifestyle interventions for dementia risk reduction?

AbstractBackgroundPhysical inactivity is a key risk factor for dementia, yet physical inactivity is common in older adults. Increasing physical activity levels in this population is an urgent health priority. Automatic, context‐dependent habits may play an important role in physical activity behaviour. This study aimed to investigate the relationship between physical activity behaviours and their automaticity in older people.Method123 community dwelling Australians aged over 65 years (M=72.2; 81 women), recruited from participant registries, local hospital noticeboards and community groups, completed an online questionnaire. Current physical activity levels were measured using the Incidental and Planned Exercise Questionnaire, and automaticity of those physical activity behaviours were measured using the Self‐Report Habit Automaticity Index. Participants also reported demographic information, falls and medical history, and current mood symptoms.ResultParticipants reported an average of 2.28 hours planned walking (SD=2.33), 5.81 hours planned moderate/vigorous exercise (SD=4.02), and 20.5 hours incidental activity (SD=15.52) per week. Multiple regression analyses revealed that after controlling for age, gender, BMI and depression symptoms, higher automaticity scores were associated with more hours per week of planned walking (p=.012), moderate/vigorous exercise (p=.038), and incidental activity (p=.017).ConclusionIn a sample of active older Australians, participants who engaged in higher levels of physical activity reported their activity to be more automatic than those reporting lower levels of activity, regardless of the type of physical activity engaged in. Supporting older people to make their physical activity more habitual could therefore be an effective approach to increase levels of physical activity in this population.

"Follow the Whistle: Physical Activity Is Calling You": Evaluation of Implementation and Impact of a Portuguese Nationwide Mass Media Campaign to Promote Physical Activity.

To raise perceived capability (C), opportunity (O) and motivation (M) for physical activity (PA) behaviour (B) among adults, the Portuguese Directorate-General of Health developed a mass media campaign named “Follow the Whistle”, based on behaviour change theory and social marketing principles. Comprehensive formative and process evaluation suggests this media-led campaign used best-practice principles. The campaign adopted a population-wide approach, had clear behavioural goals, and clear multi-strategy implementation. We assessed campaign awareness and initial impact using pre (n = 878, 57% women) and post-campaign (n = 1319, 58% women) independent adult population samples via an online questionnaire, comprising socio-demographic factors, campaign awareness and recall, and psychosocial and behavioural measures linked to the COM-B model. PA was assessed with IPAQ and the Activity Choice Index. The post-campaign recall was typical of levels following national campaigns (24%). Post-campaign measures were higher for key theory-based targets (all p < 0.05), namely self-efficacy, perceived opportunities to be more active and intrinsic motivation. The impact on social norms and self-efficacy was moderated by campaign awareness. Concerning PA, effects were found for vigorous activity (p < 0.01), but not for incidental activity. Overall the campaign impacted key theory-based intermediate outcomes, but did not influence incidental activity, which highlights the need for sustained and repeated campaign efforts.

Brown fat does not cause cachexia in cancer patients: A large retrospective longitudinal FDG-PET/CT cohort study.

BackgroundBrown adipose tissue (BAT) is a specialized form of adipose tissue, able to increase energy expenditure by heat generation in response to various stimuli. Recently, its pathological activation has been implicated in the pathogenesis of cancer cachexia. To establish a causal relationship, we retrospectively investigated the longitudinal changes in BAT and cancer in a large FDG-PET/CT cohort.MethodsWe retrospectively analyzed 13 461 FDG-PET/CT examinations of n = 8 409 patients at our institution from the winter months of 2007–2015. We graded the activation strength of BAT based on the anatomical location of the most caudally activated BAT depot into three tiers, and the stage of the cancer into five general grades. We validated the cancer grading by an interreader analysis and correlation with histopathological stage. Ambient temperature data (seven-day average before the examination) was obtained from a meteorological station close to the hospital. Changes of BAT, cancer, body mass index (BMI) and temperature between the different examinations were examined with Spearman’s test and a mixed linear model for correlation, and with a causal inference algorithm for causality.ResultsWe found n = 283 patients with at least two examinations and active BAT in at least one of them. There was no significant interaction between the changes in BAT activation, cancer burden or BMI. Temperature changes exhibited a strong negative correlation with BAT activity (ϱ = -0.57, p<0.00001). These results were confirmed with the mixed linear model. Causal inference revealed a link of Temperature ➜ BAT in all subjects and also of BMI ➜ BAT in subjects who had lost weight and increased cancer burden, but no role of cancer and no causal links of BAT ➜ BMI.ConclusionsOur data did not confirm the hypothesis that BAT plays a major role in cancer-mediated weight loss. Temperature changes are the main driver of incidental BAT activity on FDG-PET scans.

Effects of incidental physical activity on morphosyntactic processing in aging.

Older adults have difficulties in sentence comprehension when working memory (WM) load increases (e.g., multiple embedded clauses). Structured physical activity has been related to improvements in cognition; however, incidental physical activity (PA, i.e., unstructured daily physical activities), particularly incidental vigorous activity has been poorly studied in relation to its effects on behavior. Furthermore, no positive effect on language has been reported in either form of physical activity. The aim of this study was to evaluate how two levels of PA (high or low) affect WM processing and how this, in turn, may affect morphosyntactic processing in older adults. Individuals with high PA (n = 18) had a higher WM load effect than those with low PA (n = 18), both behaviorally (greater differences between high and low WM loads in correct responses) and in terms of event-related potentials (only subjects with high PA showed LAN and P600b amplitude differences between high and low WM loads). These findings suggest that PA promotes cognitive strategies to face WM loads and morphosyntactic processing.

Relationships between incidental physical activity, exercise, and sports with subsequent mood in adolescents.

Physical activity is beneficial for human physical health and well-being. Accordingly, the association between physical activity and mood in everyday life has been a subject of several Ambulatory Assessment studies. This mechanism has been studied in children, adults, and the elderly, but neglected in adolescents. It is critical to examine this mechanism in adolescents because adolescence plays a key role in human development and adolescents' physical activity behavior translates into their behavior in adulthood. We investigated adolescents' mood in relation to distinct physical activities: incidental activity such as climbing stairs; exercise activity, such as skating; and sports, such as playing soccer. We equipped 134 adolescents aged 12-17years with accelerometers and GPS-triggered electronic diaries to use in their everyday life. Adolescents reported on mood repeatedly in real time across 7days, and these data were analyzed using multilevel-modeling. After incidental activity, adolescents felt better and more energized. After exercise, adolescents felt better but less calm. After sports, adolescents felt less energized. Analyses of the time course of the effects confirmed our findings. Physical activity influences mood in adolescents' everyday life, but has distinct effects depending on the kind of physical activity. Our results suggest incidental and exercise activities entail higher post-bout valence compared to sports in competitive settings. These findings may serve as an important empirical basis for the targeted application of distinct physical activities to foster well-being in adolescence.

Factors influencing incidental 18F-FDG uptake in the gallbladder in a large cohort of patients: A retrospective study

ObjectivesThis study aims to assess the incidence of incidental activity in the gallbladder and the factors that may contribute to it in a large cohort of patients undergoing 18F-fluorodeoxyglucose-PET/CT for cancer evaluation. Methods8096 PET/CTs were retrospectively reviewed. Data pertaining to patient demographics and PET/CT parameters were collected. Patients' records were reviewed for gallbladder disorders for up to 3 years after the exam. The presence/absence of gallbladder uptake was visually assessed. Findings were classified as focal, diffuse increased and diffuse increased wall uptake, or no uptake. Volumetric measurements of the gallbladder and SUVmax of the gallbladder, liver and blood pool were measured. Chi-square and Student's t-test were used for statistical analysis. Results54 cases (0.67%) of incidental gallbladder uptake were detected (uptake group). 162 exams without uptake were selected as control (no uptake group). The injection-to-scan interval, SUVmax of the liver and blood pool, and the gallbladder volume did not differ significantly between both groups. Higher blood glucose levels were observed in the uptake (109.9 ± 32.5) vs. no uptake group (97.4 ± 18) (p = 0.01), with levels >150 mg/dL more common in the uptake group (p = 0.004). The incidence of gallbladder disease within 3 years after imaging was higher for the uptake group (12/36) compared to the no uptake group (15/115) (p = 0.02). Diffuse increased wall uptake was more likely in the group who later developed a pathology (4/12) (p = 0.03). ConclusionIncidental gallbladder uptake in patients is independent of the injected FDG dose, injection-to-scan interval or gallbladder volume, but may be related to blood glucose level. There's a higher incidence of gallbladder pathology three years after the exam particularly in cases of diffuse increased wall uptake.

Constancy bias: When we \u201cfill in the blanks\u201d of unattended or forgotten stimuli

Our ability to form predictions about the behavior of objects outside our focus of attention and to recognize when those expectations have been violated is critical to our survival. One principle that greatly influences our beliefs about unattended stimuli is that of constancy, or the tendency to assume objects outside our attention have remained constant, and the next time we attend to them they will be unchanged. Although this phenomenon is familiar from research on inattentional blindness, it is currently unclear when constancy is assumed and what conditions are adequate to convince us that unattended stimuli have likely undergone a change while outside of our attentional spotlight. Using a simple change-detection task, we sought to show that unattended stimuli are strongly predisposed to be perceived as unchanging when presented on constant, unchanging backgrounds; however, when stimuli were presented with significant incidental visual activity, participants were no longer biased towards change rejection. We found that participants were far more likely to report that a change had occurred if target presentation was accompanied by salient, incidental visual activity. We take these results to indicate that when an object is not represented in working memory, we use environmental conditions to judge whether or not these items are likely to have undergone a change or remained constant.