Introduction: This prospective cohort study is to evaluate the effectiveness of the Gold STAMP (Success Through Assessment, Management and Prevention) intervention on reducing pressure ulcer (PU) incidence rates among nursing home residents in New York State. Methods: Nursing home residents (n = 2,480) who did not have PU at baseline were followed to calculate PU incidence. Gold STAMP educational intervention included care assessment, care practice, communication, and collaboration. Covariates included socio-demographics, selected health conditions, and functional status. Kaplan Meier survival analyses were conducted after propensity score matching (PSM) to assess the impact of the Gold STAMP intervention on PU incidence rate reduction. Results: Prevalent conditions were urinary incontinence (83%), bowel incontinence (73%), and arthritis (37%). The Kaplan-Meier survival analyses indicated that the case group had a higher percentage of residents with no PUs after 6 months of follow-up compared to the control group (94% vs. 85%; p = .06). Conclusions: The 9% PU incidence rate reduction is both clinically and financially meaningful. We suggest a longer study period to monitor the long-term effects of the Gold STAMP intervention in reducing PU incidence.