Incidence Of Cutaneous Involvement Research Articles

Cutaneous Metastasis of Bladder Cancer

Skin meta stases (SM) are infrequent secondary locations of deepneoplasia that can sometimes be indicative of primary cancer. They represent 0.2 to 10% of metastases from solid tumors [1]. The most frequent primary tumors in men were carcinoma of the lung (24%), carcinoma of the large intestine (19%), melanoma (13%), and squamous cellcarcinoma of the oral cavity (12%). The most common primary tumors in women were carcinoma of the breast (69%), carcinoma of the large intestine (9%), melanoma (5%), and carcinoma of the ovary (4%) [2]. The incidence of cutaneous involvement by all urolo gicalm alignanciesis 1.1% to 2.5% [3]. The kidneyis the most common organ to serve as a source of meta stasis to the skin [4]. Bladder cancers are lesslikely to metastasize to the skin We report a new case of skin metastases presenting as a large tumor in the thoraciclevel in a patient followed for a urothelial carcinoma of the bladder.

Cutaneous CD4+/ CD56 hematodermic neoplasm

CD4+/CD56+ hematodermic neoplasm, formerly known as blastic NK cell lymphoma, is a rare and aggressive neoplasm with a high incidence of cutaneous involvement, risk of leukemic dissemination and poor prognosis. The characteristic features are expression of the T helper inducer cell marker CD4 and the NK-cell marker CD56 in the absence of other T cell or NKcell specific markers. Because of the rarity of this disease, we describe a 48 year old woman suffering from CD4+/CD56+ hematodermic neoplasm on her cheek without leukemic infiltration.

Nodular cutaneous B-cell lymphoma of the scalp in the acquired immunodeficiency syndrome

Aggressive B-cell non-Hodgkin's lymphoma frequently complicates human immunodeficiency virus type 1 infection. Although extranodal disease is an important feature of this condition, the incidence of cutaneous involvement has not been determined. A review of 754 published cases of B-cell non-Hodgkin's lymphoma associated with human immunodeficiency virus type 1 revealed an incidence of cutaneous extranodal involvement of 8.2%, approximately equal to that seen in non-Hodgkin's lymphoma not associated with human immunodeficiency virus. Lymphoma was the initial manifestation of acquired immunodeficiency syndrome in two thirds of these cases. In particular, although the head and neck are commonly involved in non-Hodgkin's lymphoma not associated with human immunodeficiency virus, scalp involvement is uncommon in human immunodeficiency virus-associated B-cell non-Hodgkin's lymphoma, and we report the second case. The natural history and proposed pathogenesis of human immunodeficiency virus-associated non-Hodgkin's lymphoma are discussed.

Cutaneous form of polyarteritis nodosa; report of a case.

KUSSMAUL and Maier 1 in 1866 first described the disease which is now called polyarteritis or periarteritis nodosa. The term of periarteritis is an obvious misnomer, for the essential pathologic picture is that of a panarteritis. The disease is a form of inflammatory, necrotizing and obliterative panarteritis of small arteries, arterioles and, occasionally, veins. General, systemic symptoms commonly accompany the disease, but the type and occurrence of regional symptoms depend on the organs involved. The primary macroscopic lesion is a nodule from 2 to 8 mm. in diameter which is of considerable diagnostic significance when the skin is affected. Alkiewicz 2 collected from the literature 36 cases with skin involvement reported to 1933. In 1939 Ketron and Bernstein 3 added 23 more to those published by Alkiewicz and found the incidence of cutaneous involvement to be approximately 25 per cent. In 1937 Carol and Prakken 4 reported a benign cutaneous form of polyarteritis nodosa in a 19 year old