Incidence Of Acute Respiratory Infections Research Articles

Air Purifiers and Acute Respiratory Infections in Residential Aged Care: A Randomized Clinical Trial.

The effectiveness of in-room air purification for the reduction of acute respiratory infections (ARIs) in residential aged-care facilities (RACFs) is unknown. To investigate the effectiveness of in-room air purifiers with high-efficiency particulate air (HEPA)-14 filters in reducing the incidence of ARIs among residents of RACFs. This randomized clinical trial used a multicenter, double-blind, 2-period, 2-treatment crossover design for 6 months from April 7 to October 26, 2023, in 3 RACFs with a bed capacity of 50 to 100 in New South Wales, Australia. The purposive sampling approach included permanent residents in private rooms in the enrolled RACFs. Data collection was performed every 2 weeks and required no additional follow-up beyond the final data collection on October 31, 2023. An air purifier containing a HEPA-14 filter was placed in rooms of participants in the intervention group, and an air purifier without a HEPA-14 filter was placed in rooms of the control participants. The groups crossed over after 3 months. The primary outcome was the incidence of ARIs, assessed with logistic mixed-model regression. Among 135 participants randomized (70 to the intervention-first group and 65 to the control-first group), 78 (57.8%) were female; mean (SD) age was 85.2 (8.6) years. In the intention-to-treat analysis, the use of air purifiers with HEPA-14 filters did not reduce ARIs compared with the control (OR, 0.57; 95% CI, 0.32-1.04; P = .07). Among the 104 participants who completed the entire study, the intervention reduced ARI incidence from 35.6% (37 participants) in the control group to 24.0% (25 participants) in the intervention group (OR, 0.53; 95% CI, 0.28-1.00; P = .048). In this clinical trial investigating use of air purifiers with HEPA-14 filters for reducing ARIs, no significant between-group difference was found in the intention-to-treat analysis. However, a significant reduction in ARIs was identified among participants who completed the entire study. These findings may help inform future large-scale studies of respiratory infectious diseases. ANZCTR identification: ACTRN12623000347662.

The Relationsip Between Environmental Conditions and Communitiy Behavior the Incidence of Acute Respiratory Tract Infections (ARI) in Toddlers at the Lapandew

This study aims to determine the relationship between environmental conditions and community behavior with ARI. The type of research used is a cross sectional study. The population in the study were all toddlers and the sample was 220 respondents. Data collection techniques using questionnaires. Results showed There is a relationship between house ventilation and the incidence of ARI in toddlers p value = 0.014. residential density and the incidence of ARI in toddlers p value = 0.023. smoking habits and the incidence of ARI in toddlers p value =0.000. Habit of using wood fuel for cooking and the incidence of ARI in toddlers p value =0.000. Conclusion that all research variables, were related to the incidence of acute respiratory infections

Evaluation of the preventive effectiveness of russian influenza vaccines in the epidemic seasons of 2018-2021

Monitoring the effectiveness of influenza vaccines annually enables the development of measures aimed at decreasing influenza incidence, hospitalization, and mortality rates. The epidemiological effectiveness of several Russian domestic influenza vaccines was evaluated in St. Petersburg in the 2018-2021 epidemic seasons. Male and female participants (N = 6912) aged 18-23 were monitored from 2018 to 2021. Sovigripp, Grippol Plus, Ultrix, and Ultrix Quadri inactivated influenza vaccines were used for immunization. In 2018-2019, when the vaccine strains fully matched the circulating influenza viruses, prophylactic vaccination resulted in a 2.7 to 7.1-fold reduction in influenza cases. The protective effectiveness of the vaccines against influenza and acute respiratory infections (ARIs) totalled 52.4%, reaching 73.0% effectiveness against influenza after laboratory confirmation. In the epidemic season 2019-2020, when the circulating viruses and vaccine strains did not fully match, the incidence of influenza and ARIs reduced twice due to vaccination; the total vaccine effectiveness against influenza and ARIs amounted to 50.0%. The Grippol Plus, Ultrix, and Ultrix Quadri vaccines proved to be the most effective, demonstrating a total effectiveness of 70.6%-75.0% and a 65.5%-83.5% effectiveness against influenza A and B. In the 2020-2021 epidemic season, no data on the preventive effectiveness of the influenza vaccines could be obtained due to the outbreak of COVID-19 and the absence of detectable influenza virus shedding in the study participants. The results obtained are consistent with WHO experts’ estimates which indicate that modern influenza vaccines reduce the incidence of influenza in adults by 70-90% if the vaccine strains match the circulating virus strains.

Effects of the Local Environment and Nutritional Status on the Incidence of Acute Respiratory Infections Among Children Under 5 Years Old in Indonesia.

This study aimed to map the incidence of acute respiratory infections (ARIs) among under-5 children in Indonesia, address the triple burden of malnutrition, and analyze the impact of malnutrition on ARIs, taking into account the environmental and wealth disparities in Indonesia. This study utilized an ecological design, analyzing aggregate data from the Indonesia Nutrition Survey, 2022. It encompassed 33 provinces and 486 districts/cities, involving a total of 334 878 children under 5 years of age. Partial least squares structural equation modeling was employed to investigate the relationships among wealth, environment, malnutrition (stunting, wasting, and underweight), and ARIs. The proportion of ARI cases in Indonesia was generally concentrated in central Sumatra, the western and eastern parts of Java, and eastern Papua. In contrast, the northern part of Sumatra, central Kalimantan, central Sulawesi, and central Papua had a higher proportion of malnutrition cases compared to other regions. Negative associations were found between malnutrition and ARIs (path coefficient =-0.072; p<0.01) and between wealth and environment (path coefficient =-0.633; p<0.001), malnutrition (path coefficient=-0.399; p<0.001), and ARIs (path coefficient=-0.918; p<0.001). An increasing wealth index is expected to contribute to reducing ARIs, malnutrition and environmental burdens in the future. This study emphasizes the necessity for focused strategies that address both immediate health challenges and the underlying socioeconomic determinants to improve child health outcomes in the Indonesian context.

The relationship between nutritional status and the incidence of ARI In toddlers aged 1-5 years

Background: Acute Respiratory Infection (ARI) is a disease that causes the highest number of deaths (mortality) and morbidity (morbidity) in children under five in both developed and developing countries, including Indonesia. The prevalence of ARI cases in Indonesia increases every year, according to the Indonesian Ministry of Health, ARI pneumonia cases reached 386,724 (38.78%) in 2022 with 69.2% (267,733 cases) of them occurring in the 1-5 year age group. Objective: This study aims to analyze the relationship between nutritional status and the incidence of ARI in toddlers aged 1-5 years in the working area of ​​the Mulyorejo Community Health Center, Surabaya, Indonesia. Method: This research uses an analytical observational study with a cross sectional approach. The samples in this research were toddlers who visited the Mulyorejo Community Health Center, Surabaya for the period November 2023-April 2024. The sampling technique used non-probability sampling, namely the purposive sampling method. The sample size was 100 toddlers. The research instrument is medical records. Research data was analyzed using the Mann-Whitney U Test. Result: Most (76%) respondents had normal nutritional status. The results of the Mann-Whitney U test to analyze the relationship between the nutritional status of toddlers and the incidence of ARI in toddlers obtained P Value = 0.492. Conclusion: These data show that there is no relationship between nutritional status and the incidence of ARI in toddlers aged 1-5 years in the working area of ​​the Mulyorejo Community Health Center, Surabaya, Indonesia.

Features of the impact of the COVID-19 pandemic on the prevalence of certain respiratory diseases of infections etiology

The aim of the study was to assess the impact of the COVID-19 pandemic on the incidence of respiratory infections of the population of Penza region in different age groups. Material and methods. The analysis of statistical reporting data (Form 12) on the number of diseases in the service area of the medical organization in Penza region was carried out. Information was sampled on respiratory diseases of infectious etiology for the period from 2015 to 2022 and on COVID-19 morbidity in the period from 2020 to 2022 among patients of different age periods. The data is presented as a calculation per 100 thousand population. Results. In 2020, compared to 2019, there was a pronounced increase in the number of respiratory diseases (p = 0.000) in adults; in 2021, the incidence decreased slightly, being higher until 2022 than in the period before the pandemic (p = 0.000). Among children and adults, there was an increase in the incidence of acute respiratory infections in 2022 compared to 2015 (p < 0.001). Peak incidence of croup and epiglottitis among children and adolescents was observed in 2020. The incidence of COVID-19 among adolescents (8339.6) and adults (7678.5) was significantly higher than the incidence among children (5949.9) (p = 0.000). Discussion. Respiratory diseases of infectious etiology have an acute course, so primary morbidity predominates. In adults, the proportion of primary morbidity is decreasing, which may be related to an increase in chronic diseases of the respiratory system. The weak impact of the pandemic on pediatric respiratory diseases incidence is supported by the low pediatric incidence of COVID-19. The increased incidence of COVID-19 among adolescents is alarming; it supports the assumption that child and young adult populations have proven to be major gateways for the spread of COVID-19 to adults. The high incidence of croup and epiglottitis in 2020 among children (p = 0.024) and adolescents could be one of the symptoms of COVID-19 characteristic of younger age. Conclusions. COVID-19 had no effect on the increase in respiratory disease among children, but children contributed to the spread of infection among adults. There is a trend towards an increase in chronic respiratory disease in adults. RBD of infectious etiology is almost impossible to predict, except for acute laryngitis and tracheitis among adults. In adolescents and children against the background of COVID-19 infection, a large number of more severe symptoms may appear.

Severe course of whooping cough in a month-old child

Acute respiratory diseases are more and more being registered among the population. According to Rospotrebnadzor, the incidence of acute respiratory infections in the Russian Federation in 2023 amounted to 15911.94 per 100.000 of population. Whooping cough plays a special role in the structure of acute respiratory infections. The largest increase is noted in the last months of 2023. In total, 20.497 cases of whooping cough were registered in the Russian Federation for 9 months of 2023. Whooping cough is an acute anthroponotic infection caused by whooping cough bacteria (Bordetella pertussis), accompanied by catarrhal phenomena in the upper respiratory tract and paroxysmal spasmodic cough. In young children, severe forms of whooping cough are still the most common, leading to a fatal outcome. One of the severe complications in children of the first years of life is encephalopathy, with persistent organic brain damage. In adolescents and adults, whooping cough often occurs in atypical forms and is manifested by a prolonged cough, for which they receive, as a rule, ineffective therapy from a pediatrician, therapist, allergist and otorhinolaryngologist. Whooping cough refers to diseases controlled by specific prevention. However, for children of an earlier age, infection from older children in the family or from adults is typical. This article presents a clinical observation of a severe course of whooping cough in a child aged 1 month, the disease proceeded with a paroxysmal cough, mainly nocturnal, with long reprises and redness of the face, ending with apnea of varying severity and duration. Determination of the severity of the course of pertussis infection is based on a complex of clinical and laboratory data. An early and effective method of etiological verification of whooping cough in children of the first year of life is PCR (polymerase chain reaction) of nasal/oropharyngeal smears.

Возможности консервативной тактики ведения пациентов с гипертрофией и воспалением глоточной миндалины

Patients who suffer from pharyngeal tonsil hypertrophy or inflammation are very common visitors in outpatient physicians’ practice. Hypertrophy of the pharyngeal tonsil may be accompanied by persistent difficulty in nasal breathing and complications whilst adenoditis in the absence of a significant impact on the child’s quality of life and associated complications had not been regarded as a ‘pathology’ in pediatric physicians’ practice until the patient is reached the age of 7 to 9 years old. The purpose of this research was to compare the regimens of the use of the homeopathic medications in patients with pharyngeal tonsil hypertrophy or inflammation. Materials and methods used: a single-center controlled randomized observation of the use of homeopathic medications of a single active substance had been conducted in pediatric patients aged 1 to 18 y/o with pharyngeal tonsil hypertrophy or inflammation. The study included patients with pharyngeal tonsil hypertrophy or inflammation who had previously taken homeopathic single-substance medications, including in combination with standard treatment. Depending on the choice of patients (repetition of the homeopathic single-substance medications intake or prophylactic regimen) the patients were then divided into comparison groups. All of the patients had undergone both the routine examination and the ENT endoscopy, the parents’/caregivers’ satisfaction with the treatment results was then assessed using the 5-point Likert scale as well as the incidence of acute respiratory infections (ARI) in children while taking homeopathic medicines (compared to the period without taking them) and the willingness to use homeopathic medicines in the future. Results: after the ENT endoscopy (reduction in the size of the pharyngeal tonsil in 38% of cases, p≤0.001) and the parents’/caregivers’ survey (reduction in the ARI frequency in 62% of cases and high satisfaction with the treatment results), the majority of parents/caregivers have assessed the repetition of the repetition of the homeopathic single-substance medications intake as rather more effective in treatment of patients with inflammation of the pharyngeal tonsil of varying degrees of hypertrophy. Conclusion: the use of homeopathic medicines in patients with pharyngeal tonsil hypertrophy or inflammation has showed good effectiveness. According to the ENT endoscopy results before v. after the treatment and the parents’/caregivers’ survey it is preferable to repeat the homeopathic single-substance medications intake in the next adenoiditis episode. The parents’/caregivers’ readiness to go on with the homeopathic medicines’ intake ranges from 50% to 78%.

Incidence of laboratory-confirmed influenza and RSV and associated presenteeism and absenteeism among healthcare personnel, Israel, influenza seasons 2016 to 2019.

BackgroundHealthcare personnel (HCP) are at high risk for respiratory infections through occupational exposure to respiratory viruses.AimWe used data from a prospective influenza vaccine effectiveness study in HCP to quantify the incidence of acute respiratory infections (ARI) and their associated presenteeism and absenteeism.MethodsAt the start and end of each season, HCP at two Israeli hospitals provided serum to screen for antibodies to influenza virus using the haemagglutination inhibition assay. During the season, active monitoring for the development of ARI symptoms was conducted twice a week by RT-PCR testing of nasal swabs for influenza and respiratory syncytial virus (RSV). Workplace presenteeism and absenteeism were documented. We calculated incidences of influenza- and RSV-associated ARI and applied sampling weights to make estimates representative of the source population.ResultsThe median age of 2,505 participating HCP was 41 years, and 70% were female. Incidence was 9.1 per 100 person-seasons (95% CI: 5.8-14.2) for RT-PCR-confirmed influenza and 2.5 per 100 person-seasons (95% CI: 0.9-7.1) for RSV illness. Each season, 18-23% of unvaccinated and influenza-negative HCP seroconverted. The incidence of seroconversion or RT-PCR-confirmed influenza was 27.5 per 100 person-seasons (95% CI: 17.8-42.5). Work during illness occurred in 92% (95% CI: 91-93) of ARI episodes, absence from work in 38% (95% CI: 36-40).ConclusionInfluenza virus and RSV infections and associated presenteeism and absenteeism were common among HCP. Improving vaccination uptake among HCP, infection control, and encouraging sick HCP to stay home are important strategies to reduce ARI incidence and decrease the risk of in-hospital transmission.

Hubungan Kebiasaan Merokok dengan Penyakit ISPA pada Pasien di Puskesmas Mandai Kabupaten Maros

This study aims to analyze the relationship between smoking habits and the incidence of Acute Respiratory Tract Infection (ARI) in patients at Puskesmas Mandai, Maros Regency. Using quantitative methods with a correlation analytic approach and cross-sectional design, data were collected from 105 respondents from September to October 2022. The results showed that most ARI patients were children under 10 years old (51.4%), with a higher prevalence in males (58.1%). In terms of smoking status, all secondary smokers (50.5%) and the majority of tertiary smokers (37.1%) experienced ARI, while only 7.6% of primary smokers experienced ARI. Statistical analysis showed a significant association between smoking and ARI incidence (p-value less than 0.05). This finding confirms that smoking, especially in the family environment, contributes significantly to the increased incidence of ARI. It is recommended that Puskesmas Mandai conduct socialization about the dangers of smoking and further research with more respondents for more specific and comprehensive results.

Analysis of the Causes and Conditions for the Formation of a High Incidence of Acute Respiratory Infections in the Population of the Altai Krai (Part 2. Environmental factors, diagnosis of coxiellosis and tick­borne rickettsiosis)

Relevance. Altai Krai (AK) is one of the least prosperous subjects of the Russian Federation in terms of the incidence of acute respiratory infections (ARI). Results of studying long-term and intra-annual dynamics of the incidence of ARI and community-acquired pneumonia (CAP) in various population groups of the AK in 2011–2021 led to a conclusion about possible connection between the characteristics of the epidemic process of ARI and environmental factors, primarily air pollution, as well as the widespread distribution of natural and atropurgic foci of tick-borne transmissible and zoonotic infections in the territory of the AK, along with the problems of diagnostics. Aim. Assessment of the possible influence of environmental factors on the formation of a high level of registered incidence of ARI in the Altai Territory, as well as diagnostics of some natural focal and zoonotic infections with fever and respiratory symptoms. Materials and methods. A retrospective epidemiological study was conducted based on annual and monthly official statistical reporting during 2011–2021 about the morbidity of the population, demographic and environmental features of the territory of the AK for each of the municipalities (MU), the average long-term incidence rates of ARI, VBP, tuberculosis, Siberian tick typhus (STT), ixodid tick-borne borreliosis, tick-borne viral encephalitis were calculated; appeals of the population regarding tick bites; population density and annual average sulfur dioxide (SO2) emissions. Pearson correlation coefficient was used to assess the strength of the relationship between the analyzed indicators; and seasonality coefficients and the method of trend-seasonal decomposition were used to assess the intra-annual dynamics of the incidence of ARI and CAP (for the period 2011-2019). To study seroprevalence of antibodies to C. burnetii, R. sibirica and SARS-CoV-2 in febrile patients with symptoms of ARI blood samples were collected in October 2022 from ten rural districts of the AK. Results and discussion. It was established that there was a significant direct correlation between the incidence of ARI and the amount of SO2 emissions into the atmosphere (r = 0.61, p < 0.001), as well as between the incidence of ARI and population density (r = 0.53, p < 0.001). The largest share (69%) of the total number of ARI cases in the Altai Territory in 2011–2021 was attributed to the cities of Barnaul, Biysk, Rubtsovsk, Zarinsk and Novoaltaisk, which are characterized by maximum SO2 emissions and population density. An additional contribution (8% total) to the incidence of ARI in the Altai Territory was attributed to 7 rural areas with the highest levels of SO2 emissions. Regardless of the ranking for the incidence of ARI and CAP, in 9 out of 10 areas selected for the study, patients had both anamnestic and diagnostic titers of antibodies to C. burnetii and/or R. sibirica. At the same time, coxiellosis cases in these areas were not registered for 12 years, and the number of cases of STT was much less than the probable number based on the proportion of patients which were seropositive to R. sibirica and had symptoms of ARI. IgM to SARS-CoV-2 were detected in 5 out of 203 examined samples, IgG – in 188 out of 203 examined samples, moreover 13.8% of samples had 118 to 499 BAU/ml, 40.9% of samples had 500 to 5000 BAU/ml, and the rest of samples had more than 5000 BAU/ml. Conclusion. Among all the variables analyzed in the study, the greatest role in the formation of the high level of registered incidence of ARI in the AK for many years belong to the high level of air pollution with SO2 emissions, high population density and, especially, their combination. Underdiagnosis of tick-borne rickettsioses and coxiellosis is of particular importance due to the unavailability of test kits for laboratory verification. Starting from 2020, a new coronavirus infection made some contribution to the registered incidence of ARI.

Analysis of the Incidence of Acute Respiratory Infections in Children Under Five at Community Health Centres

There are still high cases of ARI in children under five, ARI is one of the 10 most common diseases in the first place in health services at the health centre. This study aims to determine the factors associated with the incidence of ARI in children under five at the Pegayut Health Centre, Ogan Ilir Regency in 2024. Quantitative analytical survey research design with a cross-sectional approach. The sampling technique used purposive sampling technique, using the slovin formula. The research sample totalled 80 respondents. Inclusion criteria are parents of children under five who visit for treatment at the Puskesmas, while the exclusion criteria are parents of children under five who are not willing to be respondents. This study was conducted on 01-28 February 2024 Data collection techniques by interview using questionnaire r. Bivariate data analysis using chi-Square test and multivariate logistic regression. The results showed that there was a relationship between occupation (p value 0.005), smoking behaviour (p value 0.017), the use of mosquito repellent (p value 0.04), the use of stove cooking utensils (p value 0.005) and the distance between the house and the highway (p value 0.02) to the incidence of ARI in children under five at the Pegayut Health Centre, Ogan Ilir Regency in 2024. The most dominant factor with the incidence of ARI in children under five at the Pegayut Health Centre, Ogan Ilir Regency in 2024 is smoking behaviour in the house (p value 0.016), (OR 0.140). The conclusion is that there is a relationship between employment, smoking behaviour, the use of mosquito repellents, the use of stove cooking utensils and the distance of the house from the highway to the incidence of ARI in children under five at the Pegayut Health Centre. Suggestions for the Puskesmas provide education related to smoking behaviour in the community, with existing programs and activities at the Puskesmas.

Geographical Analysis of Acute Respiratory Infection in Cold Desert Ladakh - India: Unraveling Spatio-temporal Dynamics and Risk Factors.

Acute respiratory infection (ARI) represents a pervasive global health concern, contributing to significant morbidity and mortality. Our findings reveal a notably high prevalence of ARI in Ladakh. Employing a cross-sectional design, the total number of households surveyed was 401, among them, the total population was 2107; males, 1153, and females, 954. The highest incidence rate of 160.26/1000 persons was observed in the age group below 14 years, followed by those above 59 years (47.76), while the age group of 14-59 exhibited the lowest incidence rate at 21.23. To explore the factors contributing to ARI in Ladakh, we employed binary logistic regression modeling. Our analysis highlights significant associations between ARI incidence and various socioeconomic and environmental determinants. Notably, primary occupation, family type, kitchen ventilation, domestic fuel consumption, crowding, and smoking behaviors within families were found to be statistically significant determinants of ARI among the sample population of Ladakh.

The Relationship between Physical Environmental Sanitation and the Incidence of Acute Respiratory Infections (ARI) in Toddlers in the Lepo-Lepo Health Center Working Area, Kendari City

Introduction : Acute Respiratory Infections are very big impact if it is not treated, especially if it attacks children. Besides being able to interfere with the child's growth and development, it can also cause death. The prevalence of ARI in 2020 was 28.3%, in 2021 it decreased to 25.3%, and in 2022 it increased again to 29.65% and in 2023 it increased to 30.8%. The aim of the research is to determine the relationship between sanitation of the physical environment in the home with the incidence of Acute Respiratory Tract Infections (ARI) in children under five in the Lepo-Lepo Health Center, Kendari City. Method : This type of research is quantitative research with a Cross Sectional Study design. The population is all 2,998 children under five at the Lepo-Lepo Health Center in 2023 and the sample is 71 children under five taken using the accidental sampling technique. Sample identity data were obtained using a questionnaire. Data on ventilation area, temperature, humidity, lighting and dust particles are carried out by observation. Result : The Chi-Square test results obtained a p value of 0.000, φ = 0.636 (ventilation area), a p value of 0.000, φ =0.611 (temperature), a p value of 0.000 and φ = 0.58 (humidity). p value 0.000, φ =0.579 (lighting),, p value 0.000 and φ =0.731 (dust particles). Conclusion: The relationship between the area of air ventilation, temperature, humidity, lighting, dust particles, with the incidence of ARI in toddlers.

The Relationship between Home Environmental Sanitation and ISPA Incidence in Toddlers in Kaleroang Village, South Bungku District, Morowali Regency

Background: Acute Respiratory Infection (ARI) is the main cause of death in toddlers which is still a health problem in Indonesia, especially in the Kaleroang Health Center UPT work area which is increasing every year. Namely, in 2020 the prevalence of ARI cases is as much as (21.7%) in 2021 as many as (28.5%) and in 2022 the prevalence will increase (28.9%). The purpose of this study was to determine the relationship between home environmental sanitation and the incidence of ARI in toddlers in Kaleroang Village, South Bungku District, Morowali Regency. Methods: This type of research is a quantitative study with a cross sectional study design. The population in this study were all mothers who had toddlers in Kaleroang Village, namely 106 people, the total sample was 84 people who were taken by random sampling . Retrieval of data using observation sheets and questionnaires. Data were analyzed statistically using the Chi-Square test. Results: The results of this study indicate that there is a relationship between home ventilation and the incidence of ARI in toddlers with a value of X2 counts (5.841) > X2 tables (3.841), house occupancy density2 counts (7.171) > X2 tables (3.841), members smoking habits family X2 counts (4,701) > X2 tables (3,841), use of mosquito coils X2 counts (10,903) > X2 tables (3,841), and immunization status X2 counts (5,409) > X2 tables (3,841). Conclusions: it can be concluded that house ventilation, house occupancy density, smoking habits of family members, use of mosquito coils, and immunization status are related to the incidence of ARI in toddlers in Kaleroang Village. It is suggested to the UPT Kaleroang Health Center to further increase education related to the risk of ARI transmission based on the environment.

Hubungan Penerapan Perilaku Hidup Bersih dan Sehat (PHBS) Keluarga terhadap Kejadian Infeksi Saluran Pernapasan Akut (ISPA) pada Balita di Puskesmas Mandai Kabupaten Maros

This study aims to explore the relationship between the implementation of clean and healthy living behaviors (PHBS) in the family with the incidence of Acute Respiratory Infections (ARI) in toddlers at Puskesmas Mandai, Maros Regency. Using a quantitative approach with a correlation analytic method, this study involved 58 toddlers aged 0-5 years who were diagnosed with ARI. The results showed that 58.6% of respondents were male, with the largest age group 0-12 months (25.9%). 74.1% of the toddlers were not exclusively breastfed, and 80.9% were underweight. In addition, 75.7% of respondents did not have the habit of washing hands with soap, and 94.8% lived in an environment with active smokers. Bivariate analysis showed a significant association between the PHBS variables and the incidence of ARI, with P values less than 0.05 for all variables. These results suggest that the implementation of exclusive breastfeeding, routine weighing of toddlers, hand washing with soap, and not smoking in the house play an important role in reducing the incidence of ARI. Therefore, health centers are advised to increase the socialization of PHBS and education about the dangers of smoking, as well as encourage the community to apply clean living behavior in everyday life. This study is expected to be the basis for improving health programs at Puskesmas Mandai and increasing public awareness about the importance of PHBS in preventing ARI.

DOMINANT RISK FACTORS FOR THE INCIDENCE OF “ACUTE RESPIRATORY INFECTION” “ARI” IN TODDLERS

Background: Acute Respiratory Infection (ARI) is a contagious illness affecting diverse age groups, including toddlers, and is among the top ten reasons for Community Health Center visits. Purpose: This study aims to analyze the influence of dominant risk factors on the incidence of ARI in toddlers. Methods: This study used an observational, analytic-cross sectional approach, at Puskesmas Kampung Lalang, Medan, in 2023. The total population was 394 toddlers (aged 0-59 months). In the determination of the number of samples using the sample size estimation formula, 198 samples were obtained by purposive sampling. Data analysis used Chi-Square test and Multiple Logistic Regression Enter Methods, with a significance level of 95%. Results: The results showed that the variables of Vitamin A administration (OR = 0.27, 95% CI: 0.10-0.77) and immunization status (OR = 0.36, 95% CI: 0.14-0.93) were associated with a decreased risk of ARI in toddlers. In contrast, exclusive breastfeeding (OR = 2.35, 95% CI: 1.11-5.01) was associated with increased risk, while the physical environment of the house (OR = 2.92, 95% CI: 1.28-6.64) was associated with increased risk of ARI. Conclusion: Vitamin A administration and immunization reduce the risk of respiratory tract infection among under-fives at Puskesmas Kampung Lalang. Exclusive breastfeeding and home conditions increased the same risk. Improving these risk factors is essential to reduce the prevalence of childhood respiratory infections in the area.

Vitamin D supplementation for prevention of acute respiratory infections in older adults: A systematic review and meta-analysis.

Acute respiratory infections (ARIs) have a substantial impact on morbidity, healthcare utilization, and functional decline among older adults. Therefore, we systematically reviewed evidence from randomized controlled trials (RCTs) to evaluate the efficacy and safety of vitamin D supplementation in preventing ARIs in older adults. PubMed, Embase, the Cochrane Library, and ClinicalTrials.gov were searched until 1 February 2024. RCTs evaluating the use of vitamin D supplements to protect older adults from ARIs were included. Two reviewers independently screened papers, extracted the data and assessed the risk of bias. Data were summarised as relative risks (RRs) or odds ratios (ORs) with corresponding 95% confidence intervals (CIs). Random effects meta-analyses were used to synthesise the results. GRADE was used to evaluate the quality of evidence. All the analysis were performed with Stata version 17. Twelve trials (41552 participants) were included in the meta-analysis. It showed that vitamin D supplementation probably does not reduce the incidence of ARIs (RR, 0.99; 95% CI, 0.97-1.02, I2 = 0%; moderate certainty). No significant effect of vitamin D supplementation on the risk of ARI was observed for any of the subgroups defined by baseline 25(OH)D concentration, control treatments, dose frequency, study duration, and participants' condition. However, there was a possibility, although not statistically significant, that vitamin D may reduce the risk of ARI in patients with a baseline 25(OH)D concentration <50 nmol/L (OR, 0.90; 95% CI, 0.79-1.04, I2 = 14.7%). Additionally, vitamin D supplements might result in little to no difference in death due to any cause, any adverse event, hypercalcinemia, and kidney stones. Vitamin D supplementation among older adults probably results in little to no difference in the incidence of ARIs. However, further evidence is needed, particularly for individuals with vitamin D deficiency and populations residing in low and middle income countries. This study was registered on PROSPERO (CRD42023451265).

Risk Factors for The Incidence of Acute Respiratory Infection (ARI) in Toddlers in The Working Area of Tarus Primary Health Center, Kupang District

AbstractIntroduction: ARI is an acute infection that attacks one or more parts of the respiratory tract, from the nose to the deep tissues of the lungs. The number of ARI in toddlers in the Tarus primary health center in 2020 was 1.352 people and in 2021 there was a decrease of 97 people recorded, in January 2022 to February 2023, the number of ARI in toddlers increased by 1.141 cases.Methods: This research used a case-control study design. The case group is toddlers who experience ARI events, while the control group is toddlers who do not experience ARI events. The total population of toddlers in the Tarus Primary Health Center for the period January 2022 to February 2023 was 5,370 toddlers with a case group population of 1,141 toddlers and a control group population of 4,229 toddlers. The sample obtained for the case group was 117 toddlers and for the control group was 117 toddlers with a total of 234 samples.Results: The results showed no significant relationship between age (p=1.000; OR=1.000), and gender (p=0.428; OR=0.738) with the incidence of ARI in toddlers. There was a significant relationship between immunization status (p=0.000; OR=25.143), exclusive breastfeeding history (p=0.000; OR=25.016), house occupancy density (p=0.000; OR=15.416), house ventilation (p=0.000; OR=9.079) and smoking habits of family members (p=0.000; OR=9.775) with the incidence of ARI in toddlers.Conclusion : The incidence of ARI in toddlers can occur due to several risk factors such as immunization status, exclusive breastfeeding history, house occupancy density, house ventilation, and smoking habits of family members

Descriptive Epidemiology of Pathogens Associated with Acute Respiratory Infection in a Community-Based Study of K-12 School Children (2015-2023).

School-based outbreaks often precede increased incidence of acute respiratory infections in the greater community. We conducted acute respiratory infection surveillance among children to elucidate commonly detected pathogens in school settings and their unique characteristics and epidemiological patterns. The ORegon CHild Absenteeism due to Respiratory Disease Study (ORCHARDS) is a longitudinal, laboratory-supported, school-based, acute respiratory illness (ARI) surveillance study designed to evaluate the utility of cause-specific student absenteeism monitoring for early detection of increased activity of influenza and other respiratory viruses in schools from kindergarten through 12th grade. Eligible participants with ARIs provided demographic, epidemiologic, and symptom data, along with a nasal swab or oropharyngeal specimen. Multipathogen testing using reverse-transcription polymerase chain reaction (RT-PCR) was performed on all specimens for 18 respiratory viruses and 2 atypical bacterial pathogens (Chlamydia pneumoniae and Mycoplasma pneumoniae). Between 5 January 2015 and 9 June 2023, 3498 children participated. Pathogens were detected in 2455 of 3498 (70%) specimens. Rhinovirus/enteroviruses (36%) and influenza viruses A/B (35%) were most commonly identified in positive specimens. Rhinovirus/enteroviruses and parainfluenza viruses occurred early in the academic year, followed by seasonal coronaviruses, RSV, influenza viruses A/B, and human metapneumovirus. Since its emergence in 2020, SARS-CoV-2 was detected year-round and had a higher median age than the other pathogens. A better understanding of the etiologies, presentations, and patterns of pediatric acute respiratory infections can help inform medical and public health system responses.