To examine patients' expectations, the level of satisfaction, and the oral health-related quality of life (OHRQoL) with regard to the implants' immediate loading protocol (ILP) in edentate individuals. This pilot trial used a pre-post design to assess patient-centered outcomes in 18 edentate individuals (mean age 62.4±7.7years) who have received a 2-implant (unsplinted) mandibular overdenture through an ILP. Visual analog scales, the McGill denture satisfaction questionnaire, and the oral health impact profile (OHIP-20) questionnaire were used to evaluate patients' expectations, satisfaction, and OHRQoL at baseline, 2weeks, 1month, and 4months after surgery. Personality trait and socio-demographic information were obtained using the revised NEO personality inventory and a self-administered questionnaire, respectively. Non-parametric methods and Brunner-Langer approach were used to analyze the data. The participants had a wide range of expectations regarding the ILP. Expectations included short-term positive impact on aesthetics (83.3%) and social life (55.7%), as well as negative effects on comfort (5.6%), the ability to chew (11.1%), and the ability to clean the lower denture (11.1%). The ILP satisfied 94.4% of the participants, regardless of socio-demographic and personality profiles. There was a statistically significant improvement in overall satisfaction, comfort, perceived aesthetics, stability of the overdenture, and ability to chew from baseline to 2-week, 1-, and 4-month follow-up (P<0.001). There was 100% agreement among patients on recommending this procedure to others. There was a statistically significant decrease in the total OHIP scores and all its domains (P<0.001) from baseline to 2weeks. These differences remained statistically significant at 4-month follow-up. The ILP improved patients' OHRQoL, regardless of the implant loss, the socio-demographic characteristics, and personality traits. The ILP of two unsplinted implants with a mandibular overdenture significantly improved satisfaction and short-term OHRQoL, and appears to meet expectations in edentulous elders. There was 100% agreement among patients on recommending this procedure to others.