Purpose. Evaluation of the importance of spatial proximity for undertaking business cooperation in a tourist region. Method. Agglomeration economy analysis was combined with the network approach (i.e. Social Network Analysis). The method of case study was used – cooperation between various entities (actors) in five tourist municipalities united in the “Beskid Five” agreement. Semi-structured interviews were conducted with 225 entities selected in purposeful sampling. Additionally, using the appropriate software, based on postal address and data on GPS coordinates of the location of the interviewed entities, were obtained. To analyse the data, some parameters of network analysis were used (i.e. the degree centrality – i.e. in-out and out-degree) and multidimensional data analysis. In particular, the logistic regression method was used, i.e. binary logic regressions were carried out in order to determine the significance of spatial proximity for undertaking cooperation and its intensity in a tourist region. In addition, Moran Ii local statistics were determined in order to measure the occurrence and direction of spatial autocorrelation (spatial correlation coefficient within Local Indicators of Spatial Associations, LISA). Visualisation techniques were also implemented in the work. Findings. In the research, it has been shown that spatial proximity is an important factor affecting cooperation in a tourist region, because it increases the likelihood of cooperation, although this relationship is not linear. Research and conclusion limitations. The study did not cover all entities from the region, but only the so-called key actors in a network. The region selected for research is so specific that the obtained results cannot be considered as representative for other regions in Poland or in the world. In addition, cooperation was analysed without division into various forms, which may also have influence on the obtained results. Practical implications. Entrepreneurs wishing to gain economic benefits regarding cooperation should consider the location and spatial arrangement of connections between potential partners of this cooperation, taking its various forms into account. In addition, by stimulating cooperation between entrepreneurs, local authorities should look at their (municipality office) location in the tourist region and the resulting spatial and functional structure of links between entities, which may determine the scope, intensity and level of effectiveness of the cooperation undertaken. Originality. To show the importance of geographic proximity with reference to intensity of cooperation in a tourist region, analysis of the agglomeration economies and social networks was combined for the first time. Type of paper. An article presenting the results of empirical research.