Background: Diabetes Mellitus (DM) is a significant global health challenge, particularly in developing countries where it is prevalent and associated with high morbidity and mortality due to poor management and adherence to therapy. In Islamabad/Rawalpindi, the management of DM is compromised by gaps in knowledge and adherence regarding insulin use, which is crucial for effective disease control. Objective: This study aims to assess the patterns of insulin usage, adherence to therapy, and the impact of educational status on insulin management among patients with diabetes in Islamabad/Rawalpindi. Methods: A cross-sectional, descriptive, survey-based study was conducted from February to May 2023 among 240 ambulatory diabetic patients. Data were collected using structured questionnaires covering demographics, insulin usage patterns, adherence behaviors, and diabetes management knowledge. Statistical analysis was performed using SPSS version 25, employing descriptive statistics and Chi-Square tests to explore associations between variables. Results: The majority of participants (52.5%) were over 40 years old, with 55% having type 2 diabetes. Insulin pens were used by 47.1% of the participants, while 50% used syringes. Approximately 66.3% of the participants were also taking oral anti-diabetic medications. About 63.7% regularly attended routine checkups, 88.3% knew how to inject insulin, and 90.8% were aware of the timing for insulin injections. Educational interventions showed a significant impact on adherence and knowledge, with 77.5% demonstrating an understanding of diabetes. Conclusion: The study highlights the need for improved diabetes education and access to advanced insulin delivery methods to enhance adherence and management of diabetes in Islamabad/Rawalpindi. Emphasizing patient education on insulin use could lead to better disease outcomes and quality of life for diabetic patients in the region.