As the penetration of renewable energy sources (RESs), particularly wind power, continues to rise, the uncertainty in power systems increases. This challenges traditional optimal power flow (OPF) methods. This paper proposes a Calibrated Safety Constraints Optimal Power Flow (CSCOPF) model that uses the Improved Acceleration Coefficient-Based Bee Swarm algorithm (IACBS) in combination with the equivalent current injection (ECI) model. The proposed method addresses key challenges in wind-integrated power systems by ensuring preventive safety scheduling and enabling effective power incident safety analysis (PISA). This improves system reliability and stability. This method incorporates mixed-integer programming, with continuous and discrete variables representing power outputs and control mechanisms. Detailed numerical simulations were conducted on the IEEE 30-bus test system, and the feasibility of the proposed method was further validated on the IEEE 118-bus test system. The results show that the IACBS algorithm outperforms the existing methods in both computational efficiency and robustness. It achieves lower generation costs and faster convergence times. Additionally, the CSCOPF model effectively prevents power grid disruptions during critical incidents, ensuring that wind farms remain operational within predefined safety limits, even in fault scenarios. These findings suggest that the CSCOPF model provides a reliable solution for optimizing power flow in renewable energy-integrated systems, significantly contributing to grid stability and operational safety.