Idiopathic Intervertebral Disc Calcification Research Articles

Pediatric idiopathic intervertebral disc calcification of the cervical spine.

Pediatric idiopathic intervertebral disc calcification of the cervical spine.

The Spectrum of Underlying Diseases in Children with Torticollis.

To investigate the underlying conditions in children with torticollis. Between May 2016 and December 2019, 24 patients (10 girls and 14 boys; mean age, 8 years) presenting with twisted neck, neck pain, weakness of extremities, imbalance, and gait disorder were evaluated retrospectively. Five of the patients had cranial pathologies (cerebellar anaplastic ependymoma and medulloblastoma, brain stem glioma, atypical teratoid rhabdoid tumor, and acute disseminated encephalomyelitis), and five of the patients had spinal pathologies (idiopathic intervertebral disc calcification, vertebral hemangiomatosis, compression fracture, multiple hereditary exostoses, and Langerhans cell histiocytosis at C4). Six of the patients had ocular pathologies (strabismus, Duane syndrome, and Brown syndrome each in two patients). Four patients had otorhinolaryngological infections (Sandifer syndrome, esophageal atresia, reflux, and spasmus nutans, with one patient each). Detailed clinical physical examination and necessary laboratory investigation were performed for all patients. Torticollis is a sign that is not always innocent and may herald an underlying severe disease. Misdiagnosis can lead to wrong and unnecessary surgical procedures and treatments, and sometimes, the results can be damaging due to underlying severe conditions if diagnosed late. In addition, we first report a case of vertebral hemangiomatosis and temporomandibular joint ankylosis that presented with torticollis in the English medical literature.

Pediatric Idiopathic Intervertebral Disc Calcification: Single-Center Series and Review of the Literature

To review pediatric idiopathic intervertebral disc calcification (PIIVDC) within a single center and within the literature to outline the disease course, management, and outcome. A retrospective chart review was performed spanning the period between January 2001 and February 2016 for diagnoses of PIIVDC. Patient age, sex, symptoms, and history and physical and neurologic findings were reviewed. Laboratory and imaging findings, management, follow-up, and outcome also were studied. Nine cases of PIIVDC were identified; they included 6 male and 3 female patients, with an age range of 23 months to 12 years. Two patients were asymptomatic, and PIIVDC was discovered incidentally. Of the remaining 7 patients, 5 presented with neck and/or back pain, 1 with painless torticollis, and 1 with painful torticollis. One patient reported neurologic symptoms of pain radiating along 1 dermatome. Disc spaces affected were 5 cervical, 4 thoracic, and 2 lumbar, with 2 patients having more than 1 space affected. All patients were managed conservatively. In 1 case, symptoms and lesions persisted after 5 years, but the remainder had complete symptom resolution, generally within 6 months. The etiology of PIIVDC remains unknown but appears to occur spontaneously, without preceding trauma or underlying medical condition. A conservative approach to patients without severe neurologic deficit with outpatient follow-up is supported.

PEDIATRIC IDIOPATHIC INTERVERTEBRAL DISC CALCIFICATION: A SINGLE INSTITUTION CASE SERIES OF A RARE DISORDER

Abstract BACKGROUND Paediatric idiopathic intervertebral disc calcification (PIIVDC) is a rare, poorly understood condition with just over 300 reported cases in the literature since the first report in 1924. The condition is characterized by calcification of an intervertebral disc which can progress to inflammation or extrusion and lead to neck or spinal pain in some patients. OBJECTIVES We report a series of patients seen at a single institution with PIIVDC and outline the disease course, management and outcome and review the literature. DESIGN/METHODS A retrospective chart review was performed at a single institution spanning the period between January 2001 and February 2016 for diagnoses of PIIVDC. Patient age, gender, symptoms, and medical history and physical and neurologic findings were reviewed. Laboratory and imaging findings, management, follow-up, and outcome were also studied. A literature review was carried out by MEDLINE and Embase, using the search terms “pediatric disc calcification” and “disc calcification in children” between the years 1997 and 2017, in the English language. Articles were reviewed and data was extracted. RESULTS Nine cases of PIIVDC were identified (6 males, 3 females) with an age range of 1 to 14 years. Two patients were asymptomatic and PIIVDC was discovered incidentally. Of the remaining patients, five presented with neck/back pain, one painless torticollis, and one painful torticollis. One patient was noted to have pain radiating along one dermatome. Disc spaces affected were five cervical, five thoracic, and two lumbar, with two patients having more than one space affected. All patients were managed conservatively. In one case, symptoms and lesions persisted after 5-years, but the remainder had complete symptom resolution, generally within 6 months. CONCLUSION Although the etiology of PIIVDC remains unknown it appears to occur spontaneously, without preceding trauma or underlying medical condition. A conservative approach to patients without severe neurologic deficit with out-patient close follow-up is supported.

Multilevel paediatric idiopathic intervertebral disc calcification: a case study

Paediatric idiopathic intervertebral disc calcification (PIIDC) is a rare, mostly self-limiting condition in children that was first described by Baron in 1924. The aetiology is unknown and to date fewer than 400 cases have been described. PIIDC is characterised by calcifications mainly affecting the nucleus pulposus of the intervertebral disc. Most often lesions are located within the lower cervical spine, followed by the thoracic spine. The most common reported symptoms include low grade fever, localised tenderness, torticollis and decreased range of motion of the spine in the affected region. We present a case of multiple level idiopathic intervertebral calcifications in a 12-year-old male.Level of evidence: Level 5

Pediatric Idiopathic Intervertebral Disc Calcification

Pediatric Idiopathic Intervertebral Disc Calcification

Idiopathic Intervertebral Disc Calcification in a Child: An Atypical Case Involving Many Segments.

A seven-year-old girl presented to the emergency department with severe neck pain and restricted movement of sudden onset. A basic neurological examination supplemented by radiography showed calcification within the intervertebral disc at the C6-C7 level. Computed tomography and magnetic resonance imaging of the spine confirmed the diagnosis and revealed additional calcification within the spine at the C3-C4, C7-T1, T1-T2, T4-T5, and T5-T6 levels. Idiopathic intervertebral disc calcification is a rare condition in children, and its etiology remains unclear. In this report, we present a rare case of idiopathic intervertebral disc calcification at numerous levels in a seven-year-old girl. The clinical and radiographic findings, laboratory examination, and follow-up are discussed.

Acute spinal cord injury associated with multilevel pediatric idiopathic intervertebral disc calcification: case report.

Pediatric idiopathic intervertebral disc calcification (PIIVDC) is a rare condition; most cases are reported to be selflimited with conservative management. In this study, we describe a case of PIIVDC presenting with acute incomplete spinal cord injury with Brown-Séquard-plus syndrome that was treated with surgery and demonstrate the subsequent rehabilitation time course.

Acute Spinal Cord Injury Associated with Multi-level Pediatric Idiopathic or Inflammatory Intervertebral Disc Calcification (PIIVDC)

Acute Spinal Cord Injury Associated with Multi-level Pediatric Idiopathic or Inflammatory Intervertebral Disc Calcification (PIIVDC)

Two karate kids with pediatric idiopathic intervertebral disc calcification

Two karate kids with pediatric idiopathic intervertebral disc calcification

Idiopathic Intervertebral Disc Calcification in Childhood: An Atypical Case of an Uncommon Entity for Pediatric Pathologists

Calcification of the intervertebral disc is a common occurrence in the adult population, but it is rare in children. However, its radiological and clinical findings are well described in the pediatric age group, with close to 150 publications on record. In contrast, little information is available regarding the histological features of this entity, which may prove to be challenging to surgical pathologists. Here we provide a detailed description of a young patient with an inflammatory retropharyngeal mass originating in a calcified intervertebral disc. A review of the pathological features described in the literature in English, with pathogenic considerations, is presented.

Intervertebral disc calcification in children: Case description and review of relevant literature

SummaryBackground:Intervertebral disc calcification is a rare condition in children; in most cases, it is asymptomatic and therefore not diagnosed.Case Reports:In our study, we present a case of idiopathic intervertebral disc calcification within the cervical segment, at the level of C2/C3 and C4/C5 vertebrae in a 5-year-old girl with torticollis. Basic neurological examination supplemented by X-ray examination was performed, showing calcification within the cervical segment at the level of C2/C3 and C4/C5 vertebrae.Conclusions:In order to complement the diagnostics, a CT scan of the cervical spine was performed; the scan confirmed the diagnosis and revealed additional calcification of the anterior longitudinal ligament at the level of C4/C5 vertebrae.

Idiopathic intervertebral disc calcification in childhood

An 11-year-old girl presented with a 1-month history of back pain. Physical and neurological examinations were normal. Laboratory tests showed a mild increase in acute phase reactants, while x rays...