As a generalization and extension of the extensive tables of polarization asymmetries given in a previous work,1 we present here tables of helicity amplitudes for the scattering of two spin 1/2 particles in the colliding beam system (i.e. two incoming particles with opposite directions but not necessarily of equal momenta). The particles belonging to the same current may have different masses in order to describe particle excitations. The amplitudes are given for six different basic couplings connecting two vector vertices, a vector vertex at the one current and a derivative vector vertex at the other current, two derivative vector vertices, two tensor vertices, and two scalar vertices. The vertices include axial couplings by factors of type 1+cγ5. The amplitudes are written as expressions with 16 components in the six different reaction channels, namely the scattering of two fermions, of two antifermions, and of a fermion and an antifermion, the pair creation by pair annihilation, as well as the exchange scattering for two identical fermions or antifermions. The formulas may be used for an analysis which extracts the invariant coupling functions from the experimental data obtained in the colliding beam system directly without an intermediate transformation to the center of mass system.