A hybrid CFD–ML model for the prediction of sea spray icing, SPICE2, was developed in Part 1 of this study in Deshpande et al., 2024. The SPICE2 model is an extension of the ML model, SPICE, where some of the variables required for icing rate predictions: local wind speed, spray duration, spray period, and spray flux, are computed from CFD simulations. These, along with the air and water temperatures, and the salinity from the metocean data are used for the prediction of icing rates at different locations on a moving vessel. The existing full-scale icing measurements proved to be not detailed enough for the purpose of the verification of sea spray icing prediction models and the verification of the SPICE2 required distribution of sea spray icing data on the vessel surface in addition to the vessel design for simulation. A full-scale sea spray icing test was conducted in 2018 by Sundsbø et al. on a fully enclosed lifeboat equipped for the Goliat field in the Barents Sea. The 3D design of the same lifeboat, together with the corresponding metocean conditions and ship characteristics was used for the simulation of the vessel-specific parameters required for the verification of the icing rate and distribution prediction from the SPICE2 model against the measured distribution of sea spray icing rates on the lifeboat surface. The availability of the 3D model of this lifeboat, in addition to the fact that the icing measurements from this test were detailed enough to attempt a model verification served the purpose of validating the SPICE2 model. The icing rates measured on this lifeboat are used for the full-scale validation of the SPICE2 model that is proposed in Part 1 of this study. It was seen that the icing rates predicted by SPICE2 concurred with 9 of 13 selected locations on the lifeboat. The ones which did not showed very little deviation from the measurements. The icing rate and distribution prediction with SPICE2 were satisfactorily validated against full-scale icing measurements. This is a first attempt in modelling sea spray generation using CFD and further research into CFD for the estimation of spray flux is suggested.