With the rapid development of the Internet, e-commerce business has gradually emerged. However, its logistics distribution route planning method has problems such as redundancy of logistics data, which cannot achieve centralized planning of distribution paths, resulting in low e-commerce logistics distribution efficiency and long distribution distances, higher cost. Therefore, in order to improve the ability of logistics distribution path planning, this paper designs an e-commerce logistics distribution path planning method based on improved genetic algorithm. Optimize the analysis of e-commerce logistics distribution nodes, establish a modern logistics distribution system, and optimize the total transportation time and transportation cost under the location model of the logistics distribution center. Using hybrid search algorithm and improved genetic algorithm parameters, an improved genetic algorithm distribution path planning model is established to select the optimal path of logistics distribution, and realize e-commerce logistics distribution path with high accuracy, low error and good convergence. planning. According to the experimental results, the method in this paper can effectively shorten the distance of e-commerce logistics distribution path, reduce the number of distribution vehicles, reduce distribution costs, improve distribution efficiency, and effectively achieve centralized planning of logistics distribution. Therefore, the e-commerce logistics distribution route planning method based on improved genetic algorithm has high practical application value.