According to the data of some geophysicists (1-4), from the end of the XXth century the full vector of the mag- netic field of the Earth, following jerks, periodic secular excursions, is gradually weakening. Accordingly the buffering properties of the Earth magnetosphere, which protects biosystems from excess solar proton-electron beams, are decreas- ing. Using modeled weakening of the geomagnetic field we had to answer the question: what are the possible biotropic consequences of pressing for further human development? The aim of the research was the prognostic evaluation of the possible genetically conditioned polyfunctional human reac- tions of healthy male volunteers (n-39) aged 18-20 years to repeated weakening of the magnetic field of the Earth and, if necessary, the development of preventive non-medicinal technologies. Results. Significant differences (P <0.05) between volunteers in the experimental and control groups on the dynamics of electric, psychophysiological and other parameters, coupled with the appropriate genetic markers (genes D4, B1, TNF), and intensity of factors at different stages of ontogeny of the examinees and their parents were showed . The phenomenon of heliophysical expression of genes, manifested at modeling of the short-term prolonged geomag- netic deprivation, was opened. It is shown, that drinking water AquaHelios has helioprotective properties and contrib- utes to significant positive inversion of the functional dependence of many human functional systems on heliogeophysical impacts, increasing at geomagnetic deprivation. The necessity for the creation of a global system of geoecological human life support in conditions of spreading heliogeophysical changes of our biosphere and long space missions are scientifi- cally substantiated.