Huge Role In Development Research Articles

استخدام الاعشاب في العلاجات البيطرية لمواشي المربين المحليين

The herbs have a huge role in development of pharmacology besides the role of veterinary medicine in development of human medicine The study aimed to evaluate the therapeutic efficacy of pomegranate peel and leaves of both thuja and tobacco in 5 cows, 15 sheep and 15 goats were brought to veterinary clinics on the outskirts of Baghdad suffering from health problems in the skin, upper respiratory tract and digestive system. Cases were treated topically or orally as a powder, aqueous solution, or ointment. The results showed that 66% of cases were cured. The cure rate was related to the severity of the infection or lesion, course of treatment, routes of administration and herbal formula. Also, the results did not show any side effects of the herbal during the treatment period. Pour- on using of tobacco leaf infusion for lice-infected goats gave a better result than in sheep. The thuja and peels of pomegranate have proven to healing as an ointment for wounds, sores and blisters. Also, the aqueous solution or powder of thuja and peel of pomegranate have proven effective in reducing symptoms in the digestive system and upper respiratory disorders. Both ointments of thuja and pomegranate gave acceptable results for the treatment of warts (papilloma). Therefore, the farmer can use these herbs in emergencies. Recommendation is conducting more clinical veterinary studies on pomegranate, thuja, and tobacco leaves and their medicinal propriety. Thus, the field of veterinary medicine is the best field for reviving biopharmaceutical research and comparative medicine.

დისტანციური მუშაობა საქართველოს უმაღლესი განათლების სისტემაში - გამოწვევები და შესაძლებლობები

Georgian universities as business entities are faced with new reality provoked by Covid-19. Distance learning became accompanying part of teaching as providing service to students. It is a challenge for university administrations to provide quality service and education and on the other hand, create pleasant working conditions for lecturers to perform uninterruptedly. This article identifies the challenges that arise from changes around the world and also offers few recommendations for managers/ administrations to manage their human resources effectively while telecommuting. 21st century is an era of changing environments and the progress is made in every field. The world is changing at a mile in a minute due to globalization, technological development, consumer habit changes, process reviews, pressure from new business entrants and competitors arising out of nowhere, focus on benefits and etc. These driving factors make us to be more changeable and adaptive to the current events. Popular directions of evolution and surviving, such as Darwinism, turned into one rule (simple and difficult at the same time) – if you want to survive, you need to change. Everything around us develops rapidly. This process has been accelerated by the Covid-19 pandemic. The pandemic has changed lifestyle, work and education style. While the whole world found itself surrounded by restrictions and limitations, the quality of life should have been stayed the same. Therefore, everything including education system has moved to a remote setup. Education system has a substantial impact on country’s economy and Georgia is part of this scheme. Since education plays a huge role in development, it is crucial to maintain the quality of distance learning. Covid-19 virus has covered enormous scales and has changed the daily lifestyle of the whole world. While the countries were under lockdown, they had to adapt an alternative working style, which is telecommuting. Working from distance became the main style of working which has covered all business units, including universities. At the current time, many researches have been carried out and many scientific literatures explaining telecommuting as a working practice. The number of universities that offer students online classes are growing fast. It is interesting how university’s administration manages their human resources on distance, because in a new reality it is a challenge. Communication between the employees and their supervisors is another important aspect that has significant effect of whole distance learning process. As it is known, communication and feedback are crucial for job satisfaction and performance of the employees. However, the type of personality plays a role in the telecommuting process and the satisfaction of the telecommuter, which is supported by the need of strong communication. For some people face-to-face communication is the most effective way to do their job. University administration should provide the same amount of feedback to lecturers that work from distance as for the lecturers who teaches at university. Problem of communication, feedback and lack of face-to-face interactions are solved by using modern technologies, such as video calls, conferences, classes and etc. However, this partly eliminates the issue, because lack of face-to-face communication remains one of the problematic topics and to overcome it, is a challenge for administrations. To sum up the discussion, it is without the doubt that by different kind of factors telecommuting is now the part of our daily life and organizations, especially higher educational organizations must have well-prepared procedures and tools to manage distance working process effectively. As we mentioned, to get higher education is one of the main priorities for many countries, because it educated people and labor force create and maintain strong economy. That is why higher education system should be in the center of attention in every aspect.

Endoplasmic reticulum stress induced by an ethanol extract of Coicis semen in Chang liver cells

BackgroundIt is well known that endoplasmic reticulum (ER) stress plays a huge role in development of metabolic diseases. Specially, ER stress-induced cellular dysfunction has a significant involvement in the pathogenesis of human chronic disorders.This study was designed to study to assess whether an ethanol extract of Coicis Semen (CSE) and coixol induces the ER stress in Chang liver cells.MethodsCoicis Semen was mixed with 95% ethanol at a ratio of 1:10 (w/v) and freeze dried. Chang liver cells were seeded to 96-well plates and treated with or without CSE (100, 200, 300, 500, or 1000 μg/mL) or coixol (100, 200, 300, 500, 750, or 1000 μg/mL). cell viability was analyzed with MTT assay. Effects of CSE and coixol on expression of the genes for ER stress markers were determined with qRT-PCR and the expression of the protein levels of ER stress markers were determined with western blotting.ResultsThe concentration causing 50% inhibition (IC50) for CSE and coixol was 250 and 350 μg/mL, respectively. The CSE and coixol increased the gene expression of BiP and CHOP in a dose-dependent manner. Furthermore, CSE and coixol dose-dependently increased the the expression of XBP1.ConclusionsCSE or coixol may have cytotoxic effect to Chang liver cells and, may induce ER stress and stimulate the UPR via activation of the PERK and IRE1 pathways in normal liver cells.

Using Historical Heritage as a Factor in Tourism Development

The historical and cultural heritage plays huge role in development of internal tourism. For many Russian regions use of historical and cultural heritage becomes one of real opportunities of economic, social and cultural recovery. Objects of historical and cultural heritage, being an important asset of the cities, make profit and significantly influence their economic development. Leveling seasonal fluctuations and providing additional job openings–the historical and cultural heritage plays huge role in the social sphere. Reviving local cultural values, developing national creativity, and traditions - the historical and cultural heritage promotes cultural lifting of local population. The article studies experiment of countries of Eastern Europe on use of historical heritage of cities for the purpose of social and economic development of region.