Honey Drink Research Articles

Optimization of Pregnant Women's Knowledge about Nausea, Vomiting and the Use of Ginger Honey Drink to Reduce Nausea, Vomiting

Nausea and vomiting that occurs in the first trimester of pregnancy is caused by increased levels of the hormones Estrogen and Human Chorionic Gonadotropin (HCG) in the serum from the placenta. Nausea, vomiting often occurs when you wake up in the morning, which is also called morning sickness. The aim of this community service is to optimize pregnant women's knowledge about the benefits of ginger-honey drinks to reduce nausea and vomiting in pregnant women in the first trimester. This activity is carried out by providing education about nausea and vomiting in the first trimester of pregnancy by giving a pre-test questionnaire about nausea and vomiting before being given counseling and post test questionnaire about nausea and vomiting after being given counseling. Then they carried out a demonstration on making Honey Ginger leaf drink and immediately distributed it for pregnant women to drink. This counseling was carried out at the Mawar posyandu in the working area of the Karang Indah Community Health Center, Merauke district, which was attended by 23 pregnant women. The results of the counseling before the counseling was given were 13 pregnant women (57%) with good knowledge and after the activity there was an increase in knowledge to 22 pregnant women (96%) with good knowledge. It is hoped that there will be more emphasis on treating nausea and vomiting by utilizing the natural wealth around us, namely ginger and honey.

Al-Hijamah (Prophetic Wet Cupping Therapy) is a Novel Adjuvant Treatment for Viral Hepatitis That Excretes Viral Particles and Excess Ferritin Percutaneously, Synergizes Pharmacotherapy, Enhances Antiviral Immunity and Helps Better HCC Prevention and Treatment: A Novel Evidence-Based Combination with Prophetic Medicine Remedies.

Viral hepatitis progresses to liver cirrhosis and HCC. Several challenges are facing Sovaldi treatment to viral C hepatitis, eg, viral resistance, difficulty to treat all genotypes, and inability to access treatments in low-income countries. Also, current treatments to Hepatitis B are still challenging. Ideal treatments to viral hepatitis should decrease the viral load, enhance antiviral immunity and repair the viruses-induced tissue damage. That is still beyond reach. High serum ferritin in viral hepatitis correlates with chronicity, increased necro-inflammation, hepatotoxicity, progression to cirrhosis, progression to HCC, unresponsiveness to treatments and viremia. Previously, Al-hijamah (wet cupping therapy of prophetic medicine) significantly cleared thalassemic children of causative pathological substances (CPS), eg, excess ferritin, free radicals and serum lipids. Moreover, Al-hijamah significantly increased the antioxidant power and potentiated the natural antiviral immunity, eg, increasing CD4 count, CD8 count and CD4/CD8 ratio. Prophet Muhammad peace be upon him said: "If there is a benenvolence (benefit) in any of your medicines, benefit will be in shrtat mihjam (Al-hijamah), honey drink, and a stinge of fire compatible with disease and I do not like to cauterize". Likewise, the author suggests Al-hijamah as a novel promising adjuvant treatment for viral hepatitis (B and C) for percutaneous excretion of CPS as hepatitis viral particles, excess ferritin, inflammatory mediators, free radicals, and antigen-antibody complexes. Published reports proved that Al-hijamah exerted tissue-protective effects, and cleared blood through the fenestrated skin capillaries in a pressure-dependent and size-dependent manner (a kidney-like manner). That collectively may decrease the viral load for better HCC prevention and supports the evidence-based Taibah theory (Taibah mechanism). Same therapeutic benefits apply to other viral illnesses as AIDS. Even after HCC development, Al-hijamah is quite mandatory for excretion and clearance of CPS that favor malignancy, eg, lactate (Warburg effect), growth factors, metalloproteinases, and others. Al-hijamah-induced immune potentiation benefits HCC patients. Combining Al-hijamah with other natural antioxidant remedies of prophetic medicine, eg, nigella sativa, costus, natural honey, Zamzam water and others will maximize the therapeutic benefits. In conclusion, Al-hijamah and other prophetic medicine remedies are recommended adjuvants to current pharmacological treatments to viral hepatitis and HCC.

Phytochemical Phytochemical Compounds and Antihyperglycemic Activities from Beverage Composed Pluchea indica Less-Black Tea-Honey

Pluchea indica Less has been developed into tea bag because it contains a number of phytochemical compounds, such as lignin, terpenes, benzoids, phenylpropanoids, alkanes, saponins, catechins, alkaloids, tannins, sterols, phenolhydroquinones, and flavonoids, which have been shown to have several biological activities, such as antioxidants, anti-inflammatory, anticholesterol, and antihyperglycemic. In its development, pluchea tea can be combined with black tea to produce certain functional values. Consumption of pluchea-black tea in daily life can be done with the addition of lemon or honey to increase antihyperglycemic activity. However, this study focused on determining the profile of phytochemical compounds and antihyperglycemic activity of pluchea-black tea honey drink. The research design used was a Randomized Block Design (RAK) with one factor including honey concentration consisting of six treatment levels: 0, 1, 2, 3, 4 and 5% (v/v). Each treatment was repeated four times. Parameters carried out are the profile of phytochemical compounds and antihyperglycemic activity through in vitro analysis, namely the activity of inhibiting a-amylase and a-glucosidase enzymes. The results showed that the use of honey in the manufacture of pluchea-black tea had an effect on the profile of phytochemical compounds and antihyperglycemic activity. The use of honey with a concentration of 5% produced the highest antihyperglycemic activity, 73.21±3.57% for the ability to inhibit the alpha-amylase enzyme and 77.27±5.25% for the ability to inhibit the alpha-glucosidase enzyme, respectively

Total microbe, physicochemical property, and antioxidative activity during fermentation of cocoa honey into kombucha functional drink

Cocoa honey is a by-product of cocoa bean processing and is rich in sugars and minerals that is suitable as medium for fermentation, from which then it could be used for making potential kombucha functional drink. It is an approach to upgrading cocoa honey product. This study evaluated total microbes, physicochemical aspect, antioxidant activity, and phenolic and flavonoid compounds during the fermentation of cocoa honey kombucha. The fermentation time significantly affected the properties of cocoa honey functional beverages. Total acidity, cellulose weight, viable counts, and antioxidative activity increased during the 8-day fermentation. On the contrary, pH and total soluble solids decreased after 6 days of fermentation. Based on antioxidative activity, the good quality of kombucha was confirmed after 6 days of fermentation. During this time, the kombucha cacao honey drink demonstrated high antioxidant activity (70.14% ±1.15% DDPH and 43.49% ± 0.52% ABTS), which correlated with the high levels of phenols (144.75 ± 2.03 mg GAEq/mL) and flavonoids (1.776 mg QAEq/mL). It is expected to help in further research on the production of kombucha functional drink.

Effect of Acacia Honey Drink Consumed Pre and During Exercise on Glucose Metabolism, Total Antioxidant Status, and Running Performance in the Heat

Introduction: This study investigated the effects of Acacia honey drink on glucose metabolism, plasma total antioxidant status, selected physiological parameters and time trial running performance in the heat compared to a commercially-available sports drink. Materials and methods: Ten participants completed two endurance running trials in the heat with either honey drink (H) or sports drink (SPD) ingestion. Honey drink or sports drink was ingested one hour prior to the experimental trials. Participants warmed up for 5 min by running at 50% of their respective VO2max, and subsequently ran at 60% of their respective VO2max for 1hour. This was immediately followed by a 20 min time trial running performance. Participants drank 3 mL.kg body weight-1 of cool honey or sports drink every 20 min during the trials. Blood samples were collected for subsequent biochemical analysis. Results: Plasma glucose, insulin, cortisol, total antioxidant status and running performance were not statistically different between H and SPD trials. These findings indicated that Acacia honey drink and sports drink ingested before and during exercise elicited similar effects on glucose metabolism and endurance running performance. Conclusion: Acacia honey has potential to be used as an alternative ergogenic aid for athletes who train and compete in a hot and humid environment.

Effects of Acacia Honey Drink after Exercise-Induced Dehydration on Selected Physiological Parameters and Subsequent Running Performance

This study examined the effect of honey supplementation on exercise performance and biochemical markers in comparison to plain water and sports drink in the heat. Ten recreational athletes (Age: 22.2 ± 2.0 years, weight: 65.7 ± 5.3 kg; height: 170.4 ± 3.5 cm; VO2max: 51.5 ± 3.7 mL.kg−1.min−1) participated in this study. Participants ran at 70% of their VO2max for 1 h in a pre-load phase (Run-1), followed by a rehydration phase for 2 h and then a 20 min self-paced time trial (Run-2). After Run-1, participants drank either Acacia honey, sports drink or plain water with an amount equivalent to 150% of body weight loss. Subsequently, the participants performed the 20 min self-paced time trial. Acacia honey elicited an improved running time trial performance with a significantly (p<0.05) longer distance ran compared to plain water trial, but it was not different from the sports drink trial. In addition, there was no significant difference in running performance between sports drink and plain water trials. Plasma glucose, insulin and free fatty acids were significantly (p<0.05) higher in H and sports drink compared to the W trial during the rehydration phase. There were no significant differences in body weight changes, oxygen uptake, heart rate, rate of perceived exertion, tympanic temperature, plasma volume changes, plasma cortisol, urine osmolality, volume, and specific gravity among the three trials. Thus, Acacia honey can be recommended to be used as a rehydration drink for individuals who train and compete in the heat.

The Effect of Dehydration on the Development of Endothelial Dysfunction in Young Athletes: a Comparative Analysis of the Effectiveness of a New Honey Isotonic Drink and Standard Means of Restoring Hydro-Electrolytic Balance

Aim of the research. To prove the effectiveness of using isotonic honey drink “Gold F25 IsoDrink Light” (IsoDrink-L) based on the study of the hydration process and endothelial function in young athletes. Materials and methods. A randomized controlled study was performed in young athletes under the age of 18 years. Athletes of the main group (n = 40) consumed IsoDrink-L for a month; athletes of the control group (n = 34) consumed water and isotonic drink “X”. A bioimpedance-based device was used to determine the total amount of water, the absolute and relative proportions of intra- and extracellular water, as well as the ratio of extracellular water to the total amount of water. Hematocrit, specific gravity and color of morning urine, samples with reactive hyperemia and hyperventilation in the brachial artery, including the determination of the endothelial sensitivity index were assessed. Results. All athletes had dehydration in the form of extracellular dehydration, cellular hyperhydration, “blood thickening”, hyponatremia, increased specific gravity and urine color, as well as endothelial dysfunction. All symptoms disappeared after using IsoDrink-L for 1 month. No dynamics was observed in the control group, where 95 % of the athletes took water and 5 % – isotonic drink “X”. ROC analysis showed that the endothelial sensitivity index with a sensitivity of 95.8 % and a specificity of 99.4 % detects endothelial dysfunction. The canonical correlation coefficient between the set of hydration-dependent and endothelium-dependent signs was R = 0.71 (p < 0.0001). We established the danger of uncontrolled water consumption for rehydration in young athletes, as well as the high efficiency of isotonic honey drink and the evidence for its use for the correction of dehydration and endothelial dysfunction. A low awareness of athletes, doctors and coaches about the importance of using effective methods of rehydration in children’s sports was revealed. Conclusion. It was found that water imbalance in young athletes directly or indirectly contributes to the development of endothelial dysfunction, thereby increasing cardiovascular risk. Original approaches to the development of honey isotonic drink for young athletes with proven hydrating and endothelium-protective properties are proposed.

Blood immune function parameters in response to combined aerobic dance exercise and honey supplementation in adult women

To date, information on the effectiveness of combined aerobic dance exercise with honey supplementation on immune function in women is lacking. The present study investigated the effects of 8 weeks of combined aerobic dance exercise and honey supplementation on blood immune function parameters in adult women. In this study, forty four healthy sedentary women (25–40 year-old) were assigned into four groups with n = 11 per group: sedentary without supplementation control (Con), honey supplementation (H), aerobic dance exercise (D) and combined aerobic dance exercise with honey supplementation (HD) groups. Aerobic dance exercise was carried out for one hour per session, three sessions per week for eight weeks. Honey drink was consumed by H and HD groups, in a dosage of 20 g of honey diluted in 300 ml of plain water, consumed 7 days a week for 8 weeks. In HD group, the participants were required to consume honey drink 30 min before performing exercise. Before and after 8 weeks of experimental period, blood samples were taken to determine the concentrations of immune parameters which include full blood counts and immunophenotyping measurements. It was found that after 8 weeks of experimental period, there were statistically significant increases in T cytotoxic (CD8) (p < 0.05) in HD group. Additionally, the percentages increase in total lymphocyte counts, T helper (CD4), and T cytotoxic (CD8) counts after 8 weeks were the highest in HD group among all the groups. As conclusion, combined aerobic dance and honey supplementation may have potential to enhance immune functions in women.

Carboxymethyle Cellulose (CMC) Addition In Term of Taste, Aroma, Color, pH, Viscosity, and Turbidity of Apple Cider Honey Drink

Apple cider honey drink was modified product from fresh honey with apple cider, but there were pectin and tannin in apple cider effected agglutination and needed stabilizier as CMC. The result objective of this study was to know the best consentration of CMC addition in term of taste, aroma, color, pH, viscosity, and turbidity of apple cider honey drink. The experiment design used was completely randomized design consist four treatments and four replications. The treatments were CMC addition P0 (no addition of CMC), P1 (CMC 0.05 %), P2 (CMC 0.1 %), and P3 (CMC 0.15 %). Conclussion of the hedonic test for taste 7.06; aroma 6.61; pH 6.45; lightness (L*) 21.775; redness (a*) 9.4; yellowness (b*) 10.4; viscosity 1.039 Cp; and turbidity 185.750 NTU

Effects of Preoperative Honey Drink on Gastric Content, Perioperative Discomfort and Insulin Resistance in Patients Undergoing Open Colorectal Surgery a Randomized, Controlled Trial

Background and Aims: Preoperative fasting and surgery cause uncomfortable condition, metabolic stress and insulin resistance for the patient. A recent study in colorectal patients indicates that even small elevations of insulin resistance increase the risk of complications. Preoperative carbohydrate can reduce perioperative discomfort and insulin resistance. We investigated the effects of honey as preoperative carbohydrate-rich drink on the residual gastric contents, Original Research Article Sudiyatmo et al.; BJMMR, 14(7): 1-8, 2016; Article no.BJMMR.24374 2 perioperative discomfort, and insulin resistance. Methods: Randomized, prospective, controlled study. Thirty colorectal cancer patients who underwent elective open colorectal surgery were randomized and divided into the treatment or control group. Patients in treatment group (n = 15) received 250 ml water containing 50 ml honey on the evening and 2-3 hours preoperatively. Control patients (n = 15) underwent overnight fasting. Three different discomfort variables (thirst, hunger and tiredness), residual gastric content, plasma glucose, insulin concentrations and insulin resistance index were recorded during the perioperative period. Results: Patient and operative characteristics did not differ between groups. There was no statistical difference between the two groups with respect to gastric residue content. Subjective wellbeing was significantly better in the treatment group. Plasma glucose, serum insulin levels and insulin resistance index were found to remain significantly lower in the treatment group. Conclusion: The preoperative honey drink does not appear to alter the volume of residual gastric contents, suggesting that this is safe procedure. Preoperative honey intake is advantageous due to reducing perioperative discomfort and insulin resistance.

Effect of Gum Arabic on Organoleptic, Color, pH, Viscosity, and Turbidity of Apple Concentrated Honey Drink

Apple concentrated honey drink was modified product from fresh honey with apple concentrated to increase the taste, but there was aglutination because of pectin and tannin in apple concentrated and needed stabilizer as gum arabic. The purpose of this research was to find out the best consentration of gum arabic on apple concentrated honey drink in terms of taste, arorganoleptic (taste and aroma), color (L*, a*, b*), pH, viscosity, and turbidity. The treatments were without gum arabic (P0); gum arabic 0.05% (P1); gum arabic 0.1% (P2); and gum arabic 0.15% (P3). The method of this research was experiment with Completely Randomized Design (CRD) by using 4 treatment and 4 times replication. The data were analyzed by ANOVA and would be continued by Duncan’s Multiple Range Test (DMRT). The result of this research showed that consentration of gum arabic gave highly significant different effect on aroma, pH, viscosity, and turbidity, gave significant different effect on yellowness (b*), and gave no different effect on taste, lightness (L*) and redness (a*). Conclusion of this research was the adding of gum arabic 0.15% (P3) on apple concentrated honey drink gave the best quality of apple concentrated honey drink for taste 4.54±0.65, aroma 6.00±1.01, lightness (L*) 21.73±0.43, redness (a*) 9.78±0.76, yellowness (b*) 5.68±0.80, pH 6.68±0.13, viscosity 1.112±0.003 cP, and turbidity 165.13±1.55 NTU.

Effects of Post-Exercise Honey Drink Ingestion on Blood Glucose and Subsequent Running Performance in the Heat

Background:Glycogen depletion and hypoglycemia have been associated with fatigue and decrement of performance during prolonged exerciseObjectives:This study investigated the effectiveness of Acacia honey drink as a post-exercise recovery aid on glucose metabolism and subsequent running performance in the heat.Patients and Methods:Ten subjects participated in this randomized cross-over study. All subjects performed 2 trials. In each trial, all subjects went through a glycogen depletion phase (Run-1), 2-hour rehydration phase and time trial running phase (Run-2). In Run-1, subjects were required to run on a treadmill at 65% VO2max in the heat (31°C, 70% relative humidity) for 60 min. During 2-hour rehydration phase, subjects drank either plain water (PW) or honey drink (HD) with amount equivalent to 150% of body weight loss in 3 boluses (60%, 50% and 40% subsequently) at 0, 30 and 60 min. In Run-2, the longest distance covered in 20 min was recorded for determining running performance. Two-way repeated measured ANOVA and paired t-test were used for analysis.Results:Running distance in Run-2 covered by the subjects in the honey drink HD trial (3420 ± 350 m) was significantly (P < 0.01) longer compared to plain water PW trial (3120 ± 340 m). In general, plasma glucose, serum insulin and osmolality were significantly (P < 0.05) higher in HD compared to PW during the rehydration phase and Run-2.Conclusions:These findings indicate that rehydration with honey drink improves running performance and glucose metabolism compared to plain water in the heat. Thus, honey drink can be recommended for rehydration purpose for athletes who compete in the heat.

Effects of Post-Exercise Honey Drink Ingestion on Blood Glucose and Subsequent Running Performance in The Heat

Background: Glycogen depletion and hypoglycemia have been associated with fatigue and decrement of performance during prolonged exercise Objectives: This study investigated the effectiveness of Acacia honey drink as a post-exercise recovery aid on glucose metabolism and subsequent running performance in the heat. Patients and Methods: Ten subjects participated in this randomized cross-over study. All subjects performed 2 trials. In each trial, all subjects went through a glycogen depletion phase (Run-1), 2-hour rehydration phase and time trial running phase (Run-2). In Run-1, subjects were required to run on a treadmill at 65% VO2max in the heat (31°C, 70% relative humidity) for 60 min. During 2-hour rehydration phase, subjects drank either plain water (PW) or honey drink (HD) with amount equivalent to 150% of body weight loss in 3 boluses (60%, 50% and 40% subsequently) at 0, 30 and 60 min. In Run-2, the longest distance covered in 20 min was recorded for determining running performance. Two-way repeated measured ANOVA and paired t-test were used for analysis. Results: Running distance in Run-2 covered by the subjects in the honey drink HD trial (3420 ± 350 m) was significantly (P < 0.01) longer compared to plain water PW trial (3120 ± 340 m). In general, plasma glucose, serum insulin and osmolality were significantly (P < 0.05) higher in HD compared to PW during the rehydration phase and Run-2. Conclusions: These findings indicate that rehydration with honey drink improves running performance and glucose metabolism compared to plain water in the heat. Thus, honey drink can be recommended for rehydration purpose for athletes who compete in the heat.