Honey Dressings Research Articles

A Comparison of Honey and Standard Dressings on Microorganisms in Open Tibia Fractures

A Comparison of Honey and Standard Dressings on Microorganisms in Open Tibia Fractures

Outcomes of a honey and olive oil-based dressing material on wounds of women that have had a caesarean section in south-western Uganda.

Postpartum sepsis following caesarean sections among women in Uganda remains a risk. However, erratic supplies of standard dressing material make the risk a reality. Alternative wound dressing materials, therefore, remain a viable option. This study examined the outcome of a honey and olive oil-based dressing material on caesarean section wound healing. Using the Uganda Industrial Research Institute (UIRI), the study team created I-Dress, a wound dressing made of honey and olive oil. A case-series study was conducted on 25 women who received I-Dress following caesarean births at three health facilities in south-west Uganda. Vital signs (temperature, blood pressure, and heart rate) were measured, along with wound induration, dehiscence, and discharge. The primary outcome was the length of time it took for the wound to heal. The average age of the women who received I-Dress was 27.5 (±4.8) years. Following the application of I-Dress, all of the women (100%) had no wound induration or dehiscence, with only two (13%) experiencing wound discharge. The vast majority of the women (88%) had never had a Caesarean section before. The mean time required for wound healing was 2.2 (±0.7) days. The findings indicate that honey and olive oil-based dressings improve Caesarean section wound healing in terms of wound induration, dehiscence, and time to healing. These dressing materials can therefore supplement the standard dressing materials, especially in resource-constrained settings.

The Effect of Aloe Vera and Honey Dressings on Preventing Pressure Injuries in High-Risk Elderly ICU Patients: A Randomized Clinical Trial

Background: Today, due to the challenging treatment of pressure injuries, the preferred approach is prevention and care. One preventive measure is the use of specialized dressings, although very few studies have explored this area. Objectives: This study aimed to investigate the impact of using aloe vera and honey on the prevention of pressure injuries among elderly patients admitted to an intensive care unit in Qazvin, Iran, in 2022. Methods: In this randomized, single-blind clinical trial, 90 elderly patients at moderate to high risk of developing pressure ulcers were divided into three groups. Each group received a different preventive dressing on their sacral area twice a day for one week: The first group received aloe vera gel, the second group received honey, and the third group received plain gauze. Data were collected using a demographic information checklist, the Braden scale for predicting pressure injury risk, and a pressure injury grading tool. The data were analyzed using descriptive and analytical statistical tests and statistical software. Results: The mean Braden scale scores for patients in the aloe vera, honey, and simple dressing groups were 10.83 ± 1.41, 10.40 ± 1.52, and 10.30 ± 1.55, respectively (P = 0.40). Ten patients developed pressure injuries (0 in the aloe vera group, 3 in the honey group, and 7 in the simple dressing group). A statistically significant difference was found in the occurrence of pressure injuries between the aloe vera and honey groups compared to the control group (P = 0.015). Conclusions: The study revealed that aloe vera preventive dressing had a significant and favorable effect on pressure injury prevention. Further studies are recommended to validate these findings.

Effectiveness of different advanced wound dressings versus standard of care for the management of diabetic foot ulcers: a meta-analysis of randomized controlled trials for the development of the Italian guidelines for the treatment of diabetic foot syndrome.

to assess the effects of advanced wound dressings (AWD) commonly used in the treatment of predominantly neuropathic diabetic foot ulcers (DFU) The present meta-analysis was designed to support the development of the Italian Guidelines for the Treatment of Diabetic Foot Syndrome (DFS). A Medline and Embase search were performed up to April 1st, 2024 collecting all RCTs including diabetic patients or reporting subgroup analyses on diabetic patients with DFU comparing AWD with placebo/standard of care (SoC), with a duration of at least 12 weeks. Prespecified endpoints were: ulcer healing (principal), time-to-healing, frequency of dressings change, major and minor amputation, pain, and all-cause mortality. AWD assessed were: alginates; foam, hydrocolloids, hydrogels, hyaluronic acid, hemoglobin spray, silver-impregnated, sucrose octasulfate-impregnated, honey-impregnated, micro-organism-binding, and protease-modulating matrix dressings. Mantel-Haenzel Odds ratios and 95% confidence intervals (MH-OR, 95% CIs) were either calculated or extracted directly from the publications. Weighted mean differences (WMD) and 95% CIs were calculated for continuous variables. Fifteen studies fulfilled all inclusion criteria. Participants treated with AWD had a significantly higher ulcer healing rate and shorter time-to-healing in comparison with SoC/placebo (MH-OR 1.50 [0.80, 2.79], p = 0.20 and WMD:: - 24.38 [- 42.90, - 5.86] days, p = 0.010). No other significant effect on the above reported prespecified endpoints were observed. For the primary endpoint, the quality of evidence was rated as "moderate". In conclusion, AWD, particularly sucrose-octasulfate, hydrogels, hyaluronic acid, and honey dressings, can actively promote wound healing and shortening time-to-healing in patients with DFU.

The use of antimicrobial dressings for the management of diabetic foot ulcers: A survey of podiatrists in Aotearoa New Zealand.

Diabetic foot ulcers (DFUs) are commonly contaminated with pathogenic organisms and precede most diabetes-related amputations. Antimicrobial dressings are used in the treatment of DFUs; however, recent guidelines do not support their use. There are no data describing the experience of antimicrobial dressing use among podiatrists in Aotearoa New Zealand (AoNZ). This study aimed to (i) determine which antimicrobial dressings podiatrists in AoNZ use for the management of diabetic foot ulcers; and (ii) determine what factors influence AoNZ podiatrists' use of antimicrobial dressing when managing DFUs. An anonymous cross-sectional web-based survey was undertaken. Participants were AoNZ registered podiatrists who managed DFUs in their practice. The survey included questions relating to personal and professional demographic characteristics and DFU management and dressing practices. Descriptive statistics were computed to address the research aims. Responses from 43 AoNZ podiatrists were included. Participants reported both cadexomer iodine and silver dressings were the most common antimicrobial dressings used, with honey dressings being the least frequently used. The most influential factors in choosing antimicrobial dressings when managing DFUs were the presence of current infection, ulcer exudate and ability to prevent future infection. The least influential factors in choosing antimicrobial dressings when managing DFUs were patient preferences, cost of dressings and comfort of dressing/pain on removal. AoNZ podiatrists managing DFUs primarily use antimicrobial dressings containing cadexomer iodine or silver as active ingredients, while lower-cost options, such as honey and povidone iodine are less often used. Current recommendations highlight the lack of evidence to support positive outcomes from any particular antimicrobial dressing over another and advocate that exudate control, comfort and cost be prioritised in decision-making. As cost has been an increasing burden to our healthcare funding, clinicians and organisations may consider this before purchasing and stocking expensive dressings.

Outcome of Honey and Ghee Dressing as Compared to Regular Dressing Materials: A Comparative Study

Background: Ghee and honey has been advocated and used as dressing for infected wounds by Sushruta (600BC). The gratifying results observed with the dressing have prompted this study which aims to establish its efficacy in chronic infected wounds over one year period A standardised ghee and honey dressing was used to treat: chronic post- operative wounds and infected per op wounds, Honey and ghee dressing markedly reduces the foul odour and discharge, significantly improving the quality of life. The study will tell us comparative result of honey and ghee dressing as compared to expensive vacuum dressing and the regular dressing materials. Innumerable Randomised Control Trials (RCTs) reported on honey dressing for infected wounds, there is substantial evidence that ghee and honey dressing has at least comparable results to other modes of treatment. The easy availability and low cost of this treatment makes it significant in developing countries. Specially in rural population, Required permission has been from the HOD of orthopaedics. Material and Methods: Total 20 patients with compound fracture and chronic infected wound, were studied during the period of March 2023 to June 2023 at BVP RMC Loni, Maharashtra. Honey and ghee were taken from a fresh sealed box in 50:50 portion according to size of wound and mixed well then it was applied on the wound directly and covered with gauge and, the dressing was changed is cleaned with sterile normal saline as compared to normal dressing materials ie betadin, povidon iodine ointment, spirit. All Patients data was collected and compiled in Microsoft excel and were statistically analysed using appropriate statistical test using SPSS software. Results: Majority patient were males. Mean duration of wound healing among honey and ghee dressing was 15.3 and of regular dressing was 8.9 days. Conclusion: Honey is one alternative solution that can be used for non-pharmacological therapy. Honey can be used as a topical dressing .........

Efficacy of Honey-Based Wound Dressing Versus Hydrogel-Based Wound Dressing in Wound Healing Process: A Literature Review

Introduction: Wound dressing is a fundamental aspect of modern healthcare, encompassing a diverse range of materials and techniques aimed at optimizing the healing process while safeguarding against infection and further injury. By understanding the specific benefits of different types of wound dressings, healthcare professionals can optimize the healing process and improve patient outcomes Methods: This literature review was compiled using information from various open access online databases. Data were collected and analyzed. Results and Discussions: Honey dressing demonstrates superior efficacy compared to hydrogel dressing in wound management. Its multifaceted properties, such as potent antimicrobial activity, tissue regeneration promotion, and anti-inflammatory effects, render it a superior option for wound healing throughout all stages. Additionally, honey is more cost-effective than hydrogel and more easily accessible. Conclusion: The efficacy of honey dressing surpasses that of hydrogel dressing in wound management. Honey's multifaceted properties, including its potent antimicrobial activity, ability to promote tissue regeneration, and anti-inflammatory effects, make it a superior choice for wound healing across all phases.

Honey Dressing of Cutaneous Wounds on Limbs in the Traumatology Orthopaedics Department of Bouaké University Hospital

Honey Dressing of Cutaneous Wounds on Limbs in the Traumatology Orthopaedics Department of Bouaké University Hospital

Honey Therapy in Diabetic Foot Ulcers: A Promising Strategy for Effective Wound Healing

Diabetic foot ulcers (DFUs) are considered a major problem for public health, leading to high rates of lower-limb amputations. Moreover, due to the high prevalence rate of predisposing factors, the incidence rate of DFU is still rising. Although DFUs are complex in nature, foot ulceration usually precedes diabetic foot amputations. These impaired chronic wounds usually promote a microbial biofilm, commonly characterized by the presence of multidrug-resistant microorganisms, hampering the efficacy of conventional antibiotic treatments. Honey has been shown to be an effective antibacterial component, including against multidrug-resistant bacteria. Honey’s physical–chemical characteristics, such as the presence of hydrogen peroxide, its low pH levels, and its high sugar and phenolic contents, promote anti-inflammatory and antioxidative activities, improving wound healing. This review aims to explore honey’s effects in wound healing, especially for DFUs, and to show how the different physical–chemical features among different honey types might influence the treatment’s effectiveness. For this, the mechanisms by which honey can promote wound healing and the potential use of honey dressings in diabetic wounds were investigated in animal models and humans. After revising the diabetic wound impairment mechanisms, we found that most of the clinical studies that treated DFUs with honey in animal models or humans reported accelerated wound healing, greater wound contraction, and lower amputation or hospitalization rates; however, few studies characterized the features of honeys used for wound treatment, hindering the possibility of extensively comparing the different types of honey and identifying characteristics that most successfully promote wound healing. According to this review, honey is a cost-effective and safe option for DFU management.

Harnessing the sweet potential: the revival of honey dressing in modern wound care

Honey dressings have found wide application in the past and are currently experiencing a resurgence due to their beneficial properties, which aid professionals in their daily practices. Manuka honey possesses properties that are suitable for debridement of chronic wounds, stoma-therapy, and burns. This cultural article aims to review the major literature and benefits of medical honey dressing and underline five important implications (i.e., alternative care for individuals experiencing antibiotic resistance, ease of application, faster healing, shorter hospital stays, and economic convenience in countries characterized by high financial constraints) that at this stage are underdeveloped in the literature.

IMPACT OF HONEY DRESSING ON CHRONIC ULCER

Purpose: This study aims to highlight the significance of honey in wound treatment by focusing on its healing properties, main compounds responsible for healing capacity, its effectiveness in non-healing wounds, cost-effectiveness, and challenges coming its way. Background: Honey is an ancient treatment that is increasingly earning its place in modern wound care. Honey has been found to exert antioxidant, anticarcinogenic, anti-inflammatory, and antibacterial effects without antibiotic resistance, promote moist wound healing, and facilitate debridement. Composed of 80% sugar and 17% water, this supersaturated natural substance makes a splendid wound dressing. Its high osmolarity, phytochemicals, and enzymatic production of hydrogen peroxide inhibit bacterial growth, while its acidic pH and autolytic debridement, decrease inflammation and improve blood circulation to enhance epithelialization and healing with minimal scar tissue. Clinical observations suggest that honey holds significant promise as an effective treatment for several medical conditions, particularly in managing non-healing wounds. Large, contaminated wounds are difficult and expensive to treat. Thus, using honey can be an effective and economical approach to managing large wounds. Methods:A prospective observational study was conducted in the Department of General Surgery at Silchar Medical College and Hospital from August 2022 to April 2023, to evaluate the significance of honey dressing and related complications. This study included 25 cases with an average age of 38.18 (range 17-63) years, of these 19 were males and 6 were females. Result:In the results of the study, it was reported that honey in acute and chronic wounds provided rapid epithelization and wound contraction in wound healing, had anti-inflammatory and debridement effects, decreased pain, ensured infection control, shortened the time of wound healing, and was cost-effective.

Assessment framework for the selection of a potential interactive dressing material for diabetic foot ulcer

Diabetic foot ulcer is a chronic health issue leading to lower leg amputations in approximately 15% of patients with diabetics. There are many factors directly or indirectly involved in the physiology of wound healing but being a multisystem disorder, wound healing in diabetic patients retard or worsen with heavy exudates and severe microbial infections. Wound management is of prime importance and is an emerging area to incorporate wound regenerative materials in natural or synthetic dressing materials along with proper microbial control. The article aim to identify suitable dressing materials which exhibit inherent wound healing properties at the same time flexible to be used as drug carriers for slow, consistent and effective delivery of ‘functional drugs’ to the wound environment. The authors selected nine materials from the popular and well accepted dressings of patient choice, analyzed them using graph theoretic approach and ranked them on the basis of graph index values obtained. A critical review has also been done on the basis of their ranking, providing insights to the advantages, disadvantage and potential of top 5 ranked candidate materials. Alginate, Honey, Medifoam, Saline, and Hydrogel dressings were the top five candidate materials ranked respectively, even then, the authors suggests that ‘modified hydrogels’ can have the potential to be used as a future candidate in DFU treatment as it is the only material (among the top ranked ones) which can effectively used as regenerative drug carrier, while providing all other wound healing properties in relative proportions. The proposed framework can be modified and applied in the selection and ranking of materials for any kind of applications both in industry and medical fields by identifying factors influencing the final outcome of study and by listing the characteristics of the materials selected.

Healing Diabetic Ulcers with Pure Honey dressing: Literature Review

Poor peripheral circulation in patients with diabetes mellitus causes wounds to be difficult to heal. Therefore, patients with diabetes mellitus with diabetic ulcers require wound care to reduce the risk of amputation. One alternative material that can be used for wound care is the topical application of pure honey. The purpose of the study was to determine the effect of honey dressing on the healing process of diabetic ulcers through a literature review. The databases used include PubMed, ScienceDirect, Google Scholar, and Garuda. Keywords using (((honey) OR honey dressing) AND wound healing) AND diabetic ulcer) OR diabetic foot ulcer. The library sources used are from 2010-2020. The search results obtained 9,507 articles. Furthermore, articles were selected based on inclusion and exclusion criteria, obtained 11 articles. The assessment of articles uses a checklist on the JBI (Joanna Briggs Institute) assessment list. Eleven articles that met the assessment criteria were then analyzed one by one. The results showed that eleven articles showed the effect of giving honey dressing on the healing process of diabetic ulcers. A total of 3 articles showed wound healing based on changes in score, 2 articles based on changes in grade, 5 articles based on changes in wound characteristics, and 2 articles based on healing time. Of the eleven journals analyzed, honey dressing on diabetic ulcers were most effectively used in wound Grade I and II (Wagner Classification) ulcer patients who received drug therapy with a GDS <200 mg/dL and received daily wound care for 1 month. Healthcare professionals may consider using honey dressings for the treatment of diabetic ulcers. In addition to a more affordable price, honey has good benefits for wound healing. Further research is needed on the type of honey that is more effective as an ingredient in wound care.

Effect of honey dressing in the management of diabetic foot ulcers: A meta-analysis.

A meta-analysis study to assess the effect of honey dressing (HD) in the management of diabetic foot ulcer (DFU). A comprehensive literature examination till January 2023 was implemented and 1794 linked studies were appraised. The picked studies contained 882 subjects with DFUs were in the picked studies' baseline, 424 of them were using HD, and 458 were using a control. Odds ratio (OR) in addition to 95% confidence intervals (CIs) were used to calculate the consequence of HD in the management of DFUs after DFU by the dichotomous and continuous styles and a fixed or random model. The HD applied to DFUs caused a significantly higher wound healing rate (OR, 2.06; 95% CI, 1.45-2.93, P< .001) and lower wound healing time (MD, -10.42; 95% CI, -16.27- -4.58, P< .001) compared with the control. The HD applied to DFUs caused a significantly higher wound healing rate and lower wound healing time compared with the control. Although precautions should be taken when commerce with the consequences since most of the picked studies for this meta-analysis was with low sample sizes.

Topical Intervention of Natural Products Applied in Patients with Pressure Injuries: A Scoping Review.

Pressure injuries (PIs) represent a major medical and nursing problem in individuals with decreased or limited mobility. This scoping review aimed to map the controlled clinical trials with topical interventions of natural products applied to patients with PIs and to verify the existence of phytochemical similarities among these products. This scoping review was developed according to the JBI Manual for Evidence Synthesis. Controlled trials were searched in the following electronic databases from their inceptions until February 1, 2022: Cochrane Central Register of Controlled Trials, EMBASE, PubMed, SciELO, Science Direct, and Google Scholar. Studies involving individuals with PIs, individuals treated with topical natural products compared to a control treatment, and outcomes with wound healing or wound reduction were included in this review. The search identified 1,268 records. Only six studies were included in this scoping review. Data were independently extracted using a template instrument from the JBI. The authors summarized the characteristics of the six included articles, synthesized outcomes, and compared similar articles. Honey and Plantago major dressings were the topical interventions that significantly reduced wound size. The literature suggests that the effect on wound healing of these natural products may be related to the presence of phenolic compounds. The studies included in this review show that natural products can positively impact the healing of PIs. However, there are limited controlled clinical trials addressing natural products and PIs in the literature.

Comparative Study between Glycerin Magnesium Sulfate and Honey Dressing for Cellulitis

Comparative Study between Glycerin Magnesium Sulfate and Honey Dressing for Cellulitis

Effect of Honey Dressing on Wound Healing among Patients with Diabetic Foot Ulcer at Al-Ahsa, Saudi Arabia

Background: Diabetic foot ulcer (DFU) is a serious infection in people with diabetes mellitus. DFU is caused by vascular disease with diabetic neuropathy, and severe DFU leads to disability or even death. Mostly, povidone iodine dressing (PID) is used for DFU. The honey dressing (HD) may also improve wound healing in DFU as a complementary therapy. Aim: The study aimed to determine the effect of HD on the wound-healing process for DFU. Materials and Methods: A prospective observational study was conducted in the diabetic centres of selected hospitals in eastern Saudi Arabia. A total of 126 patients with DFU below grade three according to Wagner’s classification were selected by randomization and equally divided into HD (n = 63) and control (n = 63) groups. The patients were followed up with regularity, and 60 from each group were analysed, because the remaining patients lost their follow-up. Demographic variables and clinical parameters including random blood sugar and haemoglobin A1C were measured at the initial visit before intervention. The Bates-Jensen wound assessment tool was used before and after the intervention. Intervention group received HD and control group received PID for 6 weeks. The results are presented using frequency, mean, chi-squared test, independent ‘t’ test and Wilcoxon signed-rank test. Results: Among 120 patients, the demographic variables, and clinical parameters in the HD and control were homogeneous. The overall mean wound score was 41.07 ± 2.95 and 29.78 ± 2.2 before and after the intervention in the HD group respectively which was significant (p &lt; 0.0001). Mean score of control was 41.13 ± 2.43 before intervention and 38.53 ± 3.29 after intervention which was also significant (p = 0.00062). Conclusion: HD is best alternative cost-effective dressing method that promotes faster healing in DFU. It should be further promoted in healthcare settings.

Literature review: The effect of honey in pressure ulcer wound healing acceleration

Background: Pressure ulcers occur due to prolonged pressure and friction in areas of bony prominences that result in tissue injury with varying depths. To date, there is no standardized wound dressing for these ulcers. From the review of the availability and affordability aspects, honey can be used as a wound dressing because it contains anti-oxidants, anti-inflammatory, and anti-bacterial properties. This article investigates the advantages of honey dressing over other modern dressings. Methods: Literature search from online databases using relevant keywords. A total of three articles were discussed in this review article. Results: All articles agreed that giving honey to pressure ulcer wounds reduced wound size and pain. Honey-soaked gauze provided quicker pain relief during treatment and reduced discomfort with each dressing change. Wound healing was proven to be four times faster with honey compared to other topical dressings. The anti-bacterial effect of honey could not be significantly confirmed in this study. Nonetheless, honey dressings succeeded in accelerating wound healing in patients with pressure ulcers. Conclusion: Honey can be a promising alternative to topical dressings in patients with pressure ulcers.

The Efficacy of Honey Compared to Silver Sulfadiazine for Burn Wound Dressing in Superficial and Partial Thickness Burns—A Systematic Review and Meta-Analysis

Burn dressings play a vital role in protecting the patient from infection and aiding in the wound healing process. At present, the best burn wound dressing remains unknown. This study aimed to assess the efficacy of honey versus silver sulfadiazine dressing (SSD) for the treatment of superficial and partial thickness burns. We performed a systematic review and meta-analysis using the PubMed, MEDLINE and Embase databases to find relevant randomised control trials (RCTs) for inclusion. The outcomes measures included complete burn wound healing time, the proportion of wounds rendered sterile and subjective pain relief associated with the respective dressing type. This review was completed in line with PRISMA guidelines and has been registered with PROSPERO (Study ID: CRD42022337433). All studies in the English language that assessed honey versus SSD for patients with superficial or partial thickness burns were included. Quality and risk of bias assessments were performed using the Cochrane RoB2 tool. Seven studies were identified: totalling a population of 582 patients. From three studies, meta-analysis showed no significant difference in complete wound healing time (p = 0.06). Meta-analysis from five studies highlighted an overall significant difference favouring honey dressing in the proportion of wounds rendered sterile at day 7 post-injury (OR 10.80; 95% CI [5.76, 20.26]; p &lt; 0.00001; I2 = 88%). We conclude that honey dressings may be as or more effective than SSD in the treatment of superficial and partial thickness burn injuries. However, due to the low quality of available studies in this field, further research is necessary to establish the optimum burn dressing. Ideally, this should be conducted in the form of prospective three-arm RCTs in accordance with the CONSORT statement.

Complete Healing of a Heel Bedsore using Argania Honey Dressing: Case Report

Background: Chronic wounds and injuries represent a significant burden for health care professionals due to the difficulties related to their management. The selection and use of appropriate dressings have become essential for successful treatment. Honey has been used for thousands of years as a biological treatment because its bioactive components contribute to the healing process. Objective: This case report aims to demonstrate the efficiency of Argania honey dressing on pressure ulcers. Case Presentation: The wound care was achieved using pure raw Argania honey with no additives, pasteurization, or manipulation. A previous mechanical debridement process was necessary before the application of honey dressings to a right heel bedsore in a 69-year-old man who suffered an ischemic stroke. Results: This case report describes for the first time the complete healing of a right heel bedsore using Argania honey dressing. Bedsore demonstrated rapid recovery and complete healing over approximately 18 weeks (124 days, between June and October 2021). Conclusion: With the rise of natural medicines and some pathologies that are resistant to conventional treatments, Argania honey can be an asset for its therapeutic effects on the skin, but more studies are needed to explain and identify the complexity of mechanisms involved to ensure this complete healing process.