Background: The significant increase in home healthcare (HHC) driven by technological advancements, an ageing population, and heightened disease outbreaks—especially evident during the COVID-19 pandemic—has created an urgent need for improved medical waste management. Methods: This paper presents the development of a decision support system with a web-based interface designed for efficient medical waste collection in the HHC sector. Results: The system utilises Flask for backend operations, with HTML and CSS for the user interface, and manages data using JSON files. Its flexible design supports real-time adjustments for various vehicle types and changing waste production locations. It incorporates dynamic routing by employing two sophisticated metaheuristic algorithms: the Strength Pareto Evolutionary Algorithm (SPEA-2) and the Non-Dominated Sorting Genetic Algorithm (NSGA-II). This setup supports different dataset sizes and vehicle fleets, including Internal Combustion Engine (ICE) vehicles and Electric Vehicles (EVs). Conclusions: The automation reduces uncertainties in waste collection by minimising human intervention. The system is built to be easily adaptable for other sectors with minor modifications and can be expanded to test various scenarios with new selectable parameters.
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