Home-based Resistance Training Program Research Articles

Creatine supplementation and resistance training to preserve muscle mass and attenuate cancer progression (CREATINE-52): a protocol for a double-blind randomized controlled trial

BackgroundMuscle mass is important for metastatic prostate cancer survival and quality of life (QoL). The backbone of treatment for men with metastatic castration sensitive prostate cancer (mCSPC) is androgen deprivation therapy (ADT) with an androgen signaling inhibitor. ADT is an effective cancer treatment, but it facilitates significant declines in muscle mass and adverse health outcomes important to mCSPC survivors, such as fatigue, and reductions in physical function, independence, insulin sensitivity, and QoL. In non-metastatic CSPC survivors, resistance training (RT) preserves muscle mass and improves these related health outcomes, but the biggest barrier to RT in CSPC survivors of all stages is fatigue. Creatine monohydrate supplementation coupled with RT (Cr + RT) may address this barrier since creatine plays a critical role in energy metabolism. Cr + RT in cancer-free older adults and other clinical populations improves muscle mass and related health outcomes. Evidence also suggests that creatine supplementation can complement cancer treatment. Thus, Cr + RT is a strategy that addresses gaps in survivorship needs of people with mCSPC. The purpose of this parallel, double-blind randomized controlled trial is to test the effects of 52-weeks of Cr + RT compared with placebo (PLA) and RT (PLA + RT) on muscle mass, other related health outcomes, and markers of cancer progression.MethodsWe will carry out this trial with our team’s established, effective, home-based, telehealth RT program in 200 mCSPC survivors receiving ADT, and evaluate outcomes at baseline, 24-, and 52-weeks. RT will occur twice weekly with elastic resistance bands, and an established creatine supplementation protocol will be used for supplementation delivery. Our approach addresses a major facilitator to RT in mCSPC survivors, a home-based RT program, while utilizing a supervised model for safety.DiscussionFindings will improve delivery of comprehensive survivorship care by providing a multicomponent, patient-centered lifestyle strategy to preserve muscle mass, improve health outcomes, and complement cancer treatment (NCT06112990).

Home-based resistance training performed at either fast or slow speeds improves power output in older adults

PurposeWe investigated the effect of an unsupervised, body mass- home-based resistance training program in older adults performed at either a fast or slow contractile speed on changes to muscle-power, -volume, -architecture, and fatigue resistance of the knee extensors. MethodsThirty-two male older adults (age 65–88 years) were separated into 1) fast-speed exercise (Fast-group), 2) slow-speed exercise (Slow-group), and 3) no exercise (Control-group) groups. Participants in the exercise groups performed 30–45 repetitions of knee-extension and sit-to-stand exercises 3 times a week for 8 weeks with different exercise speed between the groups. Before and after the intervention period, the following variables were measured: Isotonic power, isometric strength, twitch contractile properties, muscle-activity, -architecture, and -quality, neuromuscular fatigue resistance of the knee extensors, and thigh muscle volume. ResultsPeak power was increased in both the Fast-group (+24 %, P < 0.01, d = 0.65) and Slow-group (+12 %, P < 0.05, d = 0.33) but not in the Control-group. Training increased pennation angle of the vastus lateralis in both the Fast-group (+8 %, P < 0.01, d = 0.42) and Slow-group (+8 %, P < 0.01, d = 0.42), while only the Fast-group showed increase in pennation angle of the rectus femoris (+12 %, P < 0.01, d = 0.64) and thigh muscle volume (+16 %, P < 0.01, d = 0.52). There was no time × group interaction effect for the other neuromuscular measures. ConclusionsUnsupervised, body mass- and home-based resistance training performed at either fast or slow speeds can improve muscle power in older adults, while fast-speed exercise may be preferable over slow-speed owing to the relatively greater improvement of muscle-power, −volume, −architecture, and better time efficiency.

Exercise leads to better sleep in children with inflammatory bowel disease.

The aim of our study was to investigate the effect of an exercise program on health-related quality of life (HRQoL) and sleep quality in children with inflammatory bowel disease (IBD) in remission. A total of 42 pediatric IBD patients in remission were recruited to participate in a 6-month-long home-based exercise program. Their mean age was 15.3 years (with a range of ± 2.08 years) and there were 25 boys. With regard to disease type, 22 had Crohn's disease (CD), 18 had ulcerative colitis (UC), and two had unclassified inflammatory bowel disease (IBD-U). Prior to starting the program, and after its completion, HRQoL was assessed using the IMPACT III questionnaire, and sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Patients also wore a triaxial accelerometer for 5 consecutive days before and after the completion of the exercise program to assess physical activity (PA) objectively. Study participants experienced no significant increase in their IMPACT III score (from 147.6 ± 2.7 to 149.6 ± 2.7, p = 0.106) following the completion of the exercise program. The prevalence of impaired sleep quality (PSQI > 5) decreased significantly from 30.9 to 23.8% (p = 0.027). At the baseline, participants' time spent in light PA (LPA) correlated positively with their IMPACT III score (coefficient (coef.) 0.398, p = 0.013). Following the completion of the resistance training program, the changes in the IMPACT III score correlated positively with time spent in moderate-to-vigorous PA (MVPA) (coef. 0.329, p = 0.047) and negatively with changes in PSQI score (coef. -0.493, p = 0.001). The number of children with impaired sleep quality decreased significantly following the completion of a 6-month-long home-based resistance training program but improvements in HRQoL scores did not reach statistical significance.

A Home-based Resistance Training Program to Reduce Pre-frailty in Middle-aged Adults: a Proof-of-concept Randomised Controlled Trial

A Home-based Resistance Training Program to Reduce Pre-frailty in Middle-aged Adults: a Proof-of-concept Randomised Controlled Trial

Home-Based Resistance Training Programme in Fontan Patients: It Is Feasible, Safe, and Efficient

Home-Based Resistance Training Programme in Fontan Patients: It Is Feasible, Safe, and Efficient

12 WEEKS OF HOME-BASED RESISTANCE TRAINING DECREASE VISCERAL FAT AREA DURING THE COVID-19 LOCKDOWN: A CASE REPORT

Background: The covid-19 lockdown demands several spaces for physical exercise to be closed. However, physical exercise produces physical and mental health benefits and an adequate health state. Home-based resistance training emerges as a viable alternative. We report a case of the effects of home-based resistance training on the visceral fat area in a middle-aged woman during the covid-19 lockdown. Methods: One middle-aged woman (42 years old; body mass = 53.3kg; Height = 1.61m; Body mass index = 20.6kg/m2) carried out a home-based resistance training program in a city in the interior of the state of São Paulo. The visceral fat area was analyzed through bioimpedance. Results: There was a decrease in visceral fat area, in a large magnitude (baseline = 85.9cm2 vs. follow-up = 71.3cm2; ∆%=-17%). The home-based resistance training program was effective in decreasing the visceral fat area of a middle-aged woman. Conclusions: Therefore, it is concluded that the home training program with few resources can enable the reduction of visceral fat area.

Feasibility of an Online Delivered, Home-Based Resistance Training Program for Older Adults - A Mixed Methods Approach.

BackgroundPhysical inactivity and low muscle mass are risk factors for falls, fractures and overall poor health. However, physical activity is reduced with increased age and only a fraction of older adults engages in resistance training (RT). Thus, strategies that facilitate RT among older adults are needed. The aim of the present study was to evaluate the effectiveness and user experience, and explore barriers and motivators toward an online delivered, home-based RT program in older adults with low muscle mass.MethodsThirty men and women, 70–71 years of age with low muscle mass were assigned home-based RT with online exercise videos (3 times/week, 45 min/session for 10 weeks) accompanied with an initial supervised try-out session. Quantitative outcome measures included changes in lean body mass and physical function. Semi structured one-to-one interviews with a subset of the participants (n = 8) were also conducted to generate a greater understanding of the participants experience of the digitally supported RT. The material was transcribed and analyzed with qualitative content analysis.ResultsTwenty-seven participants (90%) completed the trial. Lean body mass increased by 0.39 kg (95% CI: 0.06–0.72, p < 0.05) and chair stand time improved by 1.6 s (95% CI: 0.8–2.3, p < 0.001). No significant improvements were seen for balance or gait speed. The theme “Engaging in Digital Resistance Training with Personal Adaptation Leads to a Sense of Strength and Vitality” captured the participants experience of the intervention, where a sense of how the body was changing toward a more active lifestyle was described. Instructions, feedback, and intrinsic motivation were identified as key elements for compliance.ConclusionThe online delivered RT program for older adults with low muscle mass was feasible based on high compliance, user satisfaction, increased lean mass and improved chair-stand time. The participant experiences may explain the high compliance to the intervention and effects on outcomes. Based on these results, online delivered RT could be an accessible exercise routine for older adults with low muscle mass. More research is needed to verify the present findings and assess changes in a long-term perspective.

Feasibility and Efficacy of Telehealth-Based Resistance Exercise Training in Adolescents with Cystic Fibrosis and Glucose Intolerance.

The aims of this study were to (1) determine the feasibility of a home-based resistance exercise training (RET) program in patients with cystic fibrosis and impaired glucose tolerance using virtual personal training and (2) observe the effects completion of the RET program had on glucose metabolism, pulmonary function, body composition, and physical fitness. The feasibility of the program was defined as 80% compliance. Ten participants (15.80 ± 2.20 yr, 25.1 ± 7.4 kg/m2) began a home-based resistance training program consisting of 36 sessions supervised via online videoconferencing. Compliance scores of 78.9% (all participants) and 81.8% (without one outlier) were observed. A significant increase was observed in 2-h C-peptide levels (2.1 ng/mL; p = 0.04), with a moderate decrease in fasting glucose (−5.2 mg/dL; p = 0.11) and a moderate increase in 2-h insulin (35.0 U/mL; p = 0.10). A small decrease in the fat percentage (−1.3%; p = 0.03) was observed in addition to increases in fat-free mass (1.5 kg; p = 0.01) and the fat-free mass index (0.4; p = 0.01). Small, yet statistically significant increases were observed in V̇O2peak (0.1 L/min p = 0.01), V̇CO2peak (0.1 L/min; p = 0.01), and ventilation (5.3 L/min; p = 0.04). Telehealth-based RET is feasible in adolescents with CF and impaired glucose tolerance and elicits small yet favorable changes in insulin secretion, body composition, and exercise capacity.

Home-Based Resistance Training for Older Subjects during the COVID-19 Outbreak in Italy: Preliminary Results of a Six-Months RCT.

Background. The aim of this study was to evaluate the effect of a six-month home-based resistance-training program on muscle health and physical performance in healthy older subjects during the unique condition of home confinement caused by the COVID-19 pandemic. Methods. This was a randomized-controlled study that enrolled older participants that were allocated to either an experimental group performing the six-months exercise prescription (EXE) or a control group (CON). At the beginning (PRE), and after 6 months (POST), participants were assessed for muscle strength, balance, gait assessment and body composition by dual energy X-ray absorptiometry and magnetic resonance imaging. Normality distribution of data was checked with the D’Agostino and Pearson test and changes between PRE and POST were assessed by paired Student’s t-test while percentage and absolute changes between groups at POST were tested by unpaired t-test. Results. Nine participants were included for the final analysis: EXE, n = 5 (age: 66 ± 4; BMI: 27.5 ± 3.7) and CON, n = 4 (age: 71 ± 9; BMI: 24.2 ± 4.1). Significant PRE-to-POST changes were observed in the EXE group only in the chair-stand test (+19.8%, p = 0.048 and ES:1.0, moderate) and in total fat mass (+5.0%, p = 0.035 and ES:1.4, large) with no between-group differences. Moreover, EXE had significantly higher absolute thigh CSA values than CON at POST (14.138 ± 2977 vs. 9039 ± 1015, p = 0.0178, ES = 1.7). No other within- and between-group differences were detected. Conclusions. The home-based resistance-training program during the lockdown period, caused by the COVID-19 outbreak, determined only within-group improvement in lower limb muscle strength but not in muscle mass and composition in older subjects. Home confinement may partially explain the increase in total body fat due to a reduced daily PA regime and altered diet pattern.

Chest Expander Spring a Low Cost Home Physiotherapy-Based Exercise Rehabilitation after Total Hip Arthroplasty

Background: The demand for total hip arthroplasty (THA) is rising. Postoperative exercise rehabilitation helps patients recover normal joint functions by strengthening the muscles surrounding the replaced hip joint. In the face of rapidly increasing health care costs, ensuring widespread, cost-effective rehabilitation is a priority. However, the high cost of professionally supervised exercise rehabilitation programs limits access to program participation and, thus, to optimal recover of normal joint functions. Therefore, the development of an effective home-based, self-monitored exercise rehabilitation program is critical to promote the optimal recovery of THR patients. Purpose: The aim of this study was to assess the feasibility, evaluate the effectiveness of a specific Progressive Resistance Exercise program for improving hip muscles strength, resorting hip joint mobility and address the functional needs of the patient treated with primary total hip arthroplasty. Additionally; spreading the idea of a low-cost post-operative rehabilitation program using chest expander spring. Study Design: Prospective case series study. Patients and Methods: This was a prospective single-center clinical study with a 12-week intervention program carried out in an outpatient clinic and in home based. 120 patients (84 males) had been enrolled in this study to which primary total hip arthroplasty had been done. Patients were evaluated preoperatively, at baseline, 2 weeks postoperative, one week following last visit of follow-up and at 6 months postoperatively. Clinical outcome measures involved: Harris Hip Score (HHS), Oxford Hip Score (OHS), WOMAC activity score, range of hip movements (ROM), Timed Get Up and GO Test and 6 Minutes walking test. Results: The study included 120 patients (84 males). The mean age 65.3 years (range = 53-76 years). Results of clinical functional outcomes showed a progressive improvement at follow ups regarding : Harris Hip Score, Oxford Hip Score, WOMAC activity score ( related to pain, stiffness and physical functions), range of hip motions, time effect for Get up-and-go test and 6-minute walking distance test. The improvement is more achieved in last follow up visit and after 6 months postoperative. Conclusions: The study demonstrates that this novel low-cost solution holds promise in rehabilitation after THA, ensuring better clinical outcomes than conventional rehabilitation while reducing dependence on human resources. Considering the low cost and convenience of a home-based resistance training program, health professionals should consider this and similar exercise programs when providing guidance to THR patients particularly in low-income countries.

Safety and feasibility of a home-based six week resistance training program in juvenile idiopathic arthritis

BackgroundJuvenile idiopathic arthritis (JIA), among the most common chronic diseases of childhood, can be associated with attenuated physical activity levels, reduced fitness, decreased functionality and pain. This pilot study aimed to determine the safety, feasibility and effect of a six week resistance training program in children with JIA.MethodsYouth (8-18 years) with JIA participated in a home-based resistance training program. Participants reported pain on an electronic diary once a day for one week prior to training, then once a day on non-exercise days and three times a day (before-exercise, after-exercise, and end-of-day) on exercise days for the subsequent six weeks of training. Secondary outcome measures included inflammation (assessed by ultrasound), muscle size (assessed by ultrasound), muscle strength (assessed by dynamometer) and functional ability (assessed by childhood health assessment questionnaire), measured at baseline and post-training. Participants were also instructed to wear an accelerometer one week prior to training to estimate baseline physical activity levels. Statistical analyses included safety (pain changes and any adverse events), feasibility (adherence to program and modifications made to exercises) and effect of program (differences in secondary measures pre and post training). An alpha level of p < 0.05 was accepted as significant.ResultsSeven participants completed an average of 12.7 ± 3.4 (range 8-17) exercise sessions out of a possible 18 (70.6%). No adverse events were reported and pain did not increase over the seven weeks. Secondary measures revealed a significant increase in vastus lateralis thickness from pre to post training (p < 0.05). End-of-day pain intensity was correlated to end-of-day stiffness, fatigue and mood (r = .864, r = .581, r = -.637, respectively, p < 0.001). Pain intensity was also correlated with ratings of perceived exertion of the exercise (r = 0.324, p < 0.01). Only two children met the recommended 60 minutes of moderate to vigorous physical activity per day.ConclusionsA six week home-based resistance training program is both safe (absence of pain changes or adverse events over the six weeks) and feasible (comparable adherence rates to other exercise studies involving JIA and individually modifiable) in children with JIA.

Effects of high-velocity resistance training on muscle function, muscle properties, and physical performance in individuals with hip osteoarthritis: a randomized controlled trial

Objective: To investigate the effects of high-velocity resistance training on muscle function, muscle properties, and physical performance in patients with hip osteoarthritis by comparison with those of low-velocity resistance training. Design: Single-blind randomized controlled trial. Setting: Home-based exercise programmes. Subjects: A total of 46 women with hip osteoarthritis were randomly assigned to the high-velocity (n = 23) or low-velocity (n = 23) training group. Interventions: Both groups underwent an eight-week daily home-based resistance training programme using an elastic band. Exercises involved hip abduction, extension, and flexion and knee extension. Participants in the high-velocity group performed the concentric phase of each repetition as rapidly as possible and returned to the initial position eccentrically in 3 s. Participants in the low-velocity group performed both the concentric and eccentric phases in 3 s. Main measures: The following outcome measures were evaluated: isometric muscle strength, muscle power, muscle thickness, muscle echo intensity, maximum walking speed, Timed Up and Go test, 3-minute walking test, Harris Hip Score, and hip pain. Results: Decreases in the time for performing the Timed Up and Go test (mean changes: high-velocity group −0.46 s, low-velocity group −0.23 s) and echo intensity of the gluteus maximus (mean changes: high-velocity group −6.8, low-velocity group −1.0) were significantly greater in the high-velocity group than in the low-velocity group. No significant difference was observed in changes of other outcome measures between the groups. Conclusion: This study revealed that high-velocity training for patients with hip osteoarthritis has partially a greater effect on muscle properties and physical performance than low-velocity training.

A home-based resistance training program for survivors of prostate cancer: A pilot randomized controlled trial

Introduction: Men with prostate cancer experience a range of disease and treatment-related physical effects. Trials of resistance training (RT) with prostate cancer survivors have demonstrated the potential to improve many of the most common and debilitating symptoms. However, these trials have mainly comprised supervised programs often conducted at hospitals, limiting access for rural participants and capacity for sustainability. Home-based RT programs have the potential to overcome these limitations.Method: Get PHITT (Prostate Health Improved Through Training) was a 12 week, home-based RT program for men with prostate cancer. Men attended one face-to-face session to receive instruction from an exercise specialist and a home-based RT program (3 sessions/week), a behaviour-change support manual, and an elastic resistance device (Gymstick). The support manual incorporated evidence- and theory-informed behaviour change strategies aligned with social cognitive theory. The theoretical constructs operationalised within the support manual included self-efficacy, outcome expectations, social support, and intentions. We aimed to establish feasibility, acceptability and preliminary efficacy via a pilot wait-list RCT. Men (n=39) were recruited via local media and an existing prostate cancer support group. Participants provided patient-reported (quality of life, fatigue, depression/anxiety, acceptability [5 point likert scale SD-SA]) and objectively assessed (muscular strength, body composition, waist circumference, BMI, agility) data. We assessed recruitment and retention rate, and analysed RT log books to assess adherence.Results: The recruitment target was met within 3 days. The program achieved good fidelity (72%) and retention (90%). Intervention participants (n=18) reported that the program was enjoyable (χ¯=4), informative (χ¯=4.6), useful (χ¯=4.5), relevant (χ¯=4.2), that using the Gymstick was enjoyable (χ¯=4.7), and that they would recommend the program to other prostate cancer survivors (100%). Preliminary analyses identified improvements in global quality of life and muscular strength, and decreased fatigue amongst intervention participants that were not observed amongst control participants. Findings of all outcomes will be presented.Discussion: The Get PHITT program has demonstrated acceptability, feasibility and preliminary efficacy. The next step is evaluation in a fully powered trial. Introduction: Men with prostate cancer experience a range of disease and treatment-related physical effects. Trials of resistance training (RT) with prostate cancer survivors have demonstrated the potential to improve many of the most common and debilitating symptoms. However, these trials have mainly comprised supervised programs often conducted at hospitals, limiting access for rural participants and capacity for sustainability. Home-based RT programs have the potential to overcome these limitations. Method: Get PHITT (Prostate Health Improved Through Training) was a 12 week, home-based RT program for men with prostate cancer. Men attended one face-to-face session to receive instruction from an exercise specialist and a home-based RT program (3 sessions/week), a behaviour-change support manual, and an elastic resistance device (Gymstick). The support manual incorporated evidence- and theory-informed behaviour change strategies aligned with social cognitive theory. The theoretical constructs operationalised within the support manual included self-efficacy, outcome expectations, social support, and intentions. We aimed to establish feasibility, acceptability and preliminary efficacy via a pilot wait-list RCT. Men (n=39) were recruited via local media and an existing prostate cancer support group. Participants provided patient-reported (quality of life, fatigue, depression/anxiety, acceptability [5 point likert scale SD-SA]) and objectively assessed (muscular strength, body composition, waist circumference, BMI, agility) data. We assessed recruitment and retention rate, and analysed RT log books to assess adherence. Results: The recruitment target was met within 3 days. The program achieved good fidelity (72%) and retention (90%). Intervention participants (n=18) reported that the program was enjoyable (χ¯=4), informative (χ¯=4.6), useful (χ¯=4.5), relevant (χ¯=4.2), that using the Gymstick was enjoyable (χ¯=4.7), and that they would recommend the program to other prostate cancer survivors (100%). Preliminary analyses identified improvements in global quality of life and muscular strength, and decreased fatigue amongst intervention participants that were not observed amongst control participants. Findings of all outcomes will be presented. Discussion: The Get PHITT program has demonstrated acceptability, feasibility and preliminary efficacy. The next step is evaluation in a fully powered trial.

Effect of a Low–Resource-Intensive Lifestyle Modification Program Incorporating Gymnasium-Based and Home-Based Resistance Training on Type 2 Diabetes Risk in Australian Adults

OBJECTIVE—The purpose of this study was to assess the effectiveness of a low–resource-intensive lifestyle modification program incorporating resistance training and to compare a gymnasium-based with a home-based resistance training program on diabetes diagnosis status and risk.RESEARCH DESIGN AND METHODS—A quasi-experimental two-group study was undertaken with 122 participants with diabetes risk factors; 36.9% had impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) at baseline. The intervention included a 6-week group self-management education program, a gymnasium-based or home-based 12-week resistance training program, and a 34-week maintenance program. Fasting plasma glucose (FPG) and 2-h plasma glucose, blood lipids, blood pressure, body composition, physical activity, and diet were assessed at baseline and week 52.RESULTS—Mean 2-h plasma glucose and FPG fell by 0.34 mmol/l (95% CI −0.60 to −0.08) and 0.15 mmol/l (−0.23 to −0.07), respectively. The proportion of participants with IFG or IGT decreased from 36.9 to 23.0% (P = 0.006). Mean weight loss was 4.07 kg (−4.99 to −3.15). The only significant difference between resistance training groups was a greater reduction in systolic blood pressure for the gymnasium-based group (P = 0.008).CONCLUSIONS—This intervention significantly improved diabetes diagnostic status and reduced diabetes risk to a degree comparable to that of other low–resource-intensive lifestyle modification programs and more intensive interventions applied to individuals with IGT. The effects of home-based and gymnasium-based resistance training did not differ significantly.

Health Perceptions As Predictors of Exercise Adherence in Older Women

Purpose : To determine if health perceptions, measured by SF-36 subscales, could identify women more likely to adhere to exercise, particularly during exercise adoption and maintenance phases. Design and Methods: Subjects (Age = 67 ± 5 yr, BMI = 24.4 ± 3 kg/m2) were 189 estrogen-taking, postmenopausal women in a 2-year home-based resistance-training program. Results : Vitality, role-emotional, bodily pain, social functioning, and mental health subscales of the SF-36 were significantly (p<.05) predictive of exercise adoption. Vitality, role-emotional, general health, and bodily pain subscales were significantly (p<.05) predictive of exercise maintenance. Implications: Women who perceived themselves as having more energy, fewer emotional problems, less pain, fewer social problems, less feelings of nervousness and depression were more likely to start exercising. Women who perceived themselves as having more energy, fewer emotional problems, excellent health, less pain were more likely to continue exercising. Additionally, the present study indicated that different components of the SF-36 affected different behavior phases of adherence during the exercise program.

SIX-WEEK HOME-BASED RESISTANCE TRAINING IMPROVES MUSCLE POWER IN ADULT PATIENTS WITH GH-DEFFICIENCY

1305 GH-defficient patients have poor physical performance and lack of muscular strength and power. It is unknown how resistance training affects these individuals. Our aim was to quantify the effects of a resistance training program on their muscle power. Seven GH-defficiency adult patients (4 men/3 women) [age: 22 to 54 y.], without GH replacement and no other hormonal defficiency, had anthropometric data - height, body weight, skinfolds and girths - and muscle power measured pre- and post-six weeks of training. Muscle power were determined (Fitrodyne, Bratislava) for five exercises: seated chest press, rear lat pulldown, triceps press down, knee extension, and standing upright row. Based on evaluation, a serie of 13 exercises - 2 sets × 6 reps each -, to be performed each other day, were prescribed for home training using simple materials. Habituation effects in the testing were minimized by repeating twice - two weeks apart - before training and the values averaged for further analysis. Anthropometric data were unaffected by training, except for sum of skinfolds that decreased [182±23 vs 167±24 mm; p=.01]. Maximal muscle power increased for: rear lat pulldown [138±27 vs 196±25 W; p=.01], triceps press down [82±12 vs 129±26 W; p=.02] and standing upright row [125±27 vs 139±25 W; p=0.03]. We conclude that in GH-defficient patients a short and simple home-based resistance training program improves maximal muscle power in most exercises, despite no changes in limb girths. These data, if confirmed with large sample and long-term training programs, have potential clinical implications in therapeutic approach of adult GH-defficient patients. Partial financial support from CAPES